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The map label for this gene is yfhA [H]

Identifier: 78355926

GI number: 78355926

Start: 909072

End: 910538

Strand: Direct

Name: yfhA [H]

Synonym: Dde_0879

Alternate gene names: 78355926

Gene position: 909072-910538 (Clockwise)

Preceding gene: 78355925

Following gene: 78355928

Centisome position: 24.37

GC content: 59.99

Gene sequence:

>1467_bases
ATGTCGGAAATTGCAACACCTGCAGCCATGGTGCACAGCGGCAGGCTGTGCCTGCTGATTGTGGATGACGAGCGGGATTT
TGCCAGCGGTCTTGCGCGGCTTATTTCCAGCCGGTTCCGCGATATTGATGTGGTGCCTGTTTTCAGCGCCAAAGAAGCGC
TGGAAGTGCTGGCAGAGCGCAGTGTGCACCTGATGATGACCGACCTGCGCATGCCGGAAATGGGCGGTATGCAGCTTTTG
CGGCAGGCGCTTGAGGTGCAGCCCGGCCTCAGCATGGTGGTGCTGACGGCGCACGGCACCATAGAAACGGCCGTGGAGGC
TTTGCAGTCAGGGGCGTATGATTTTCTGACCAAGCCCATCGAGCCGGACCAGCTTTTCAGCGCGGTGGCCAAAGGGCTGG
AACGCAGCAGGCTGCTGGAAGAGAACAACAGGCTGCGCCAGATCATCTCGGCCGGAGGCGAGCCGGGCGAACTGGTGGGT
GAGGGCCGTGCCATGCAGCAGCTCAAGCGCACCATAGCTGCTGTGGCCCAGTCTGATTATACCGTGCTGGTGCGGGGCGA
ATCCGGCACGGGCAAAGAGCTGGTGGCGCGTCTGGTGCACCGGCTGGGCAATCGGGCGGGCAGACCGTTTATGGCTGTCA
ACTGCCCGGCAATCCCTGAAAATCTTCTGGAAAGCGAGCTTTTCGGTCACGTAAAGGGCGCCTTTACCGGAGCGGACAGG
GATCACAAGGGACTTTTTGCCGTGGCGGACAAAGGCACCCTGCATCTGGATGAAATAGGTGATATTTCCGCGCCCATCCA
GACAAAGTTGCTGCGCTGTCTTCAGGACGGTGAAATACGCCCGGTGGGGGCCAGCCGGTCGGAGACTGTGGATGTGCGTG
TGGTGGCCTCTACCAATCAGGACCTTGAGGCGCGCATAGCCGATAAATCATTCCGCGAAGATCTTTATTACCGGCTTAAT
GTGCTTACGGTAACGCTGCCCCCGCTGCGTGAGCGTGTGGAAGACATTCCGCTGCTGGTGCACTATCTGCTGCGCAAGGC
ATGCACCGAGATGGGGCTGGAAGAAAAGGAAATTTCGCCGGATGTCGTGGAGTGGATGACCCGCCGCACATGGCCCGGCA
ACGTGCGTGAACTGCAGAACTTTGTACGCAGACTCACGGTGTTCTGTGCCGGACGGCTGGTCGATATGGACATTATCCGC
ATGGTGGAGCAGGGCAGCGGCGGGGCAATGCCGCCGGTGGTCGCCGGCGGTCTGTCTCCGGGCGGTTTTCGCAGCGGTGA
AGGCTTTGTGCCCTACAAAGATGCCAAGGCAAAGGTGGTTGACGATTTTACCACGGCGTATCTGCGTGATCTGCTGACGT
CCGCAGGGGGCAATGTTTCCGAGGCGGCCCGCATGTCCGGTCTGTCCCGTGTGGCCCTGCAGAAAATTCTCACCCGTCTG
GACATTAACGTGGCACGATACCGCTGA

Upstream 100 bases:

>100_bases
GCGCGCTGTTTACTGTGCTGCTGCCTGCCGAAGACGGACCGGAAACGGACGGCGCGGCGTAACGCCGGCGCGTACCGGTC
AGAACAAAAGCGGAGTACGC

Downstream 100 bases:

>100_bases
GTATGTGGCTCTGTATATTGTAATTAAGAAAAGCCCGCGAACTTGTTCGCGGGCTTTTGCGGTATGACGGGACAGGGGAA
ATACATCCGGACATGCCGGT

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MSEIATPAAMVHSGRLCLLIVDDERDFASGLARLISSRFRDIDVVPVFSAKEALEVLAERSVHLMMTDLRMPEMGGMQLL
RQALEVQPGLSMVVLTAHGTIETAVEALQSGAYDFLTKPIEPDQLFSAVAKGLERSRLLEENNRLRQIISAGGEPGELVG
EGRAMQQLKRTIAAVAQSDYTVLVRGESGTGKELVARLVHRLGNRAGRPFMAVNCPAIPENLLESELFGHVKGAFTGADR
DHKGLFAVADKGTLHLDEIGDISAPIQTKLLRCLQDGEIRPVGASRSETVDVRVVASTNQDLEARIADKSFREDLYYRLN
VLTVTLPPLRERVEDIPLLVHYLLRKACTEMGLEEKEISPDVVEWMTRRTWPGNVRELQNFVRRLTVFCAGRLVDMDIIR
MVEQGSGGAMPPVVAGGLSPGGFRSGEGFVPYKDAKAKVVDDFTTAYLRDLLTSAGGNVSEAARMSGLSRVALQKILTRL
DINVARYR

Sequences:

>Translated_488_residues
MSEIATPAAMVHSGRLCLLIVDDERDFASGLARLISSRFRDIDVVPVFSAKEALEVLAERSVHLMMTDLRMPEMGGMQLL
RQALEVQPGLSMVVLTAHGTIETAVEALQSGAYDFLTKPIEPDQLFSAVAKGLERSRLLEENNRLRQIISAGGEPGELVG
EGRAMQQLKRTIAAVAQSDYTVLVRGESGTGKELVARLVHRLGNRAGRPFMAVNCPAIPENLLESELFGHVKGAFTGADR
DHKGLFAVADKGTLHLDEIGDISAPIQTKLLRCLQDGEIRPVGASRSETVDVRVVASTNQDLEARIADKSFREDLYYRLN
VLTVTLPPLRERVEDIPLLVHYLLRKACTEMGLEEKEISPDVVEWMTRRTWPGNVRELQNFVRRLTVFCAGRLVDMDIIR
MVEQGSGGAMPPVVAGGLSPGGFRSGEGFVPYKDAKAKVVDDFTTAYLRDLLTSAGGNVSEAARMSGLSRVALQKILTRL
DINVARYR
>Mature_487_residues
SEIATPAAMVHSGRLCLLIVDDERDFASGLARLISSRFRDIDVVPVFSAKEALEVLAERSVHLMMTDLRMPEMGGMQLLR
QALEVQPGLSMVVLTAHGTIETAVEALQSGAYDFLTKPIEPDQLFSAVAKGLERSRLLEENNRLRQIISAGGEPGELVGE
GRAMQQLKRTIAAVAQSDYTVLVRGESGTGKELVARLVHRLGNRAGRPFMAVNCPAIPENLLESELFGHVKGAFTGADRD
HKGLFAVADKGTLHLDEIGDISAPIQTKLLRCLQDGEIRPVGASRSETVDVRVVASTNQDLEARIADKSFREDLYYRLNV
LTVTLPPLRERVEDIPLLVHYLLRKACTEMGLEEKEISPDVVEWMTRRTWPGNVRELQNFVRRLTVFCAGRLVDMDIIRM
VEQGSGGAMPPVVAGGLSPGGFRSGEGFVPYKDAKAKVVDDFTTAYLRDLLTSAGGNVSEAARMSGLSRVALQKILTRLD
INVARYR

Specific function: Probable member of a two-component regulatory system yfhA/yfhK [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=479, Percent_Identity=39.4572025052192, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1790299, Length=476, Percent_Identity=39.0756302521008, Blast_Score=315, Evalue=5e-87,
Organism=Escherichia coli, GI1790437, Length=470, Percent_Identity=38.2978723404255, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1788550, Length=474, Percent_Identity=37.5527426160338, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1789233, Length=256, Percent_Identity=53.125, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI87082117, Length=261, Percent_Identity=45.9770114942529, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789087, Length=269, Percent_Identity=44.6096654275093, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI87082152, Length=232, Percent_Identity=47.4137931034483, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1786524, Length=254, Percent_Identity=42.5196850393701, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=44.5887445887446, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787583, Length=326, Percent_Identity=34.9693251533742, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1789828, Length=246, Percent_Identity=33.739837398374, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI87081858, Length=212, Percent_Identity=33.0188679245283, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1790102, Length=111, Percent_Identity=35.1351351351351, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53559; Mature: 53427

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIATPAAMVHSGRLCLLIVDDERDFASGLARLISSRFRDIDVVPVFSAKEALEVLAER
CCCCCCCHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHC
SVHLMMTDLRMPEMGGMQLLRQALEVQPGLSMVVLTAHGTIETAVEALQSGAYDFLTKPI
CHHEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCHHHHCCCC
EPDQLFSAVAKGLERSRLLEENNRLRQIISAGGEPGELVGEGRAMQQLKRTIAAVAQSDY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCC
TVLVRGESGTGKELVARLVHRLGNRAGRPFMAVNCPAIPENLLESELFGHVKGAFTGADR
EEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
DHKGLFAVADKGTLHLDEIGDISAPIQTKLLRCLQDGEIRPVGASRSETVDVRVVASTNQ
CCCCEEEEECCCCEECCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCEEEEEEEECCCC
DLEARIADKSFREDLYYRLNVLTVTLPPLRERVEDIPLLVHYLLRKACTEMGLEEKEISP
CHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCH
DVVEWMTRRTWPGNVRELQNFVRRLTVFCAGRLVDMDIIRMVEQGSGGAMPPVVAGGLSP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHCCCCCC
GGFRSGEGFVPYKDAKAKVVDDFTTAYLRDLLTSAGGNVSEAARMSGLSRVALQKILTRL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DINVARYR
CCHHHCCC
>Mature Secondary Structure 
SEIATPAAMVHSGRLCLLIVDDERDFASGLARLISSRFRDIDVVPVFSAKEALEVLAER
CCCCCCHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHC
SVHLMMTDLRMPEMGGMQLLRQALEVQPGLSMVVLTAHGTIETAVEALQSGAYDFLTKPI
CHHEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCHHHHCCCC
EPDQLFSAVAKGLERSRLLEENNRLRQIISAGGEPGELVGEGRAMQQLKRTIAAVAQSDY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCC
TVLVRGESGTGKELVARLVHRLGNRAGRPFMAVNCPAIPENLLESELFGHVKGAFTGADR
EEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCC
DHKGLFAVADKGTLHLDEIGDISAPIQTKLLRCLQDGEIRPVGASRSETVDVRVVASTNQ
CCCCEEEEECCCCEECCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCEEEEEEEECCCC
DLEARIADKSFREDLYYRLNVLTVTLPPLRERVEDIPLLVHYLLRKACTEMGLEEKEISP
CHHHHHHHHHHHHHHHEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCH
DVVEWMTRRTWPGNVRELQNFVRRLTVFCAGRLVDMDIIRMVEQGSGGAMPPVVAGGLSP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHCCCCCC
GGFRSGEGFVPYKDAKAKVVDDFTTAYLRDLLTSAGGNVSEAARMSGLSRVALQKILTRL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
DINVARYR
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]