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The map label for this gene is atoS [H]

Identifier: 78355925

GI number: 78355925

Start: 906511

End: 909033

Strand: Direct

Name: atoS [H]

Synonym: Dde_0878

Alternate gene names: 78355925

Gene position: 906511-909033 (Clockwise)

Preceding gene: 78355924

Following gene: 78355926

Centisome position: 24.3

GC content: 58.18

Gene sequence:

>2523_bases
ATGGCTGTGCGGGGGGCTTCTTTCGCGGCTGAGGCGCAGTCAGAAAAAAGTCTTCCGGCAATTACAAAAGGCGGCAGCTC
CGGACACGCAATGCATATTCACAAACCCACAAGCCTTCAGGCAAAATTTTTATCCGGTCTCGCCGTCGCGTGCCTCACTC
TGGGCGTTCTTTTTGCGGGCGGGTTCTACATTCACATGCGCAATGTGCTGGAAGAAGAGGTGCGCGACAAAGCGCGGCTC
ATCTTCACCCATGTGGATTCCATTCAGAATTATGTGCGGCAGGTGCTGCGCCCCACCATGTACGAACAGCTGCCCGACAC
GTTTGTCATTCAGGCCATGTCGTCGTCCTTTGTTTCCCGCAGCGTCATGAGCCGTCTTAATAACGGGCCGGACGGCACCA
TATACCGCCGTGTGGCCATAGATGCACGCAATCCCGAATACGAAGCCAACGAAAGAGAACTGGAACTCATCGATTACTTC
AGGGGCCATCCGGAAAGCGGCATCTGGCGCGGATATAAAAATATCAACGGCGACCGCTACTATGTGATGGCCCGGCCGGT
GCGCTTTGTTGAAAGCTGCATGTACTGCCACGGCGAACCGGCGGATGCCCCTGCCGACCTTGTGCGCATGTACGGCAACA
GAGGATTCGGCAAGGAACAGGATTCCATTGCCGGTGTCGACTTTGTGGGGCTGTCCGTTGACGGCAGCGTTGGGCGCCTG
CAGCGCACCATCCTGACGTATTTTGTTTTTTTCACGGTCGGAGCCGTTATCTTTTTTTCCACGACAAACCTGCTTTTCAA
GGTGCTGGTGGTCAACAATCTTAAGCGCCTGACCAATGTGTTCCGGCGCAACGTGGCCGATGCCGAGGGCAGCGCCCTGC
TGCGCAAACTGGAACAGGGTGACGAAATAGAAGAGCTGGTGGAAGGGATGGAACAGATGGGCGAGCATCTGTACGAGGCC
CGCAGCCAGCTGCAGCTGTACGCAGAGAATCTGCGCGGCATGGTTGACCAGCGCACGCAGGCGCTTTCGCGCGAGGTGGA
GGCCCGCAGGGCCGATGTGGCTCTTTTTGTCAGCCTGCTGTCTGATATGCGCAGCAGCACGTCGCGCGCCGACCTGTGGC
AGCTGGCGCTGCCTCAGATATGCCGGCGGTTCAGAGCGCGGCGCATTGCCTATGTGTGCACCATGGCCTCTCAGAATTAT
TTTTCGTGGCCGGAAAACATGGGCCGGCCCGAACTGCCGGATGACCTCGTGGGGGTGCTTACATCCGGCGCCTGTGTGGT
GCTGGGTAACAAAGCCTACATTCCGGTGGAATCAAGCGTTGGTAATGCTGAAGGTATCCTGTGCCTTTTCTGGGATACGG
ATGCCGAAGCCAACACCCATGACCGGGCAGTGCTGCAGGCACTGGGCAGACAGCTGGGCACCGTGGCGGAAAACATGACC
GCCATAGACAGCCTGATGCGGCAGATGAACGTGCTGCAGACCATTGTGGAAGGCATAACAGACCCTCTGGCGCTCATGGA
TTCCAACTGCGCTGTGCTTACTGTGAATGAGGCCGCGCGCAAACTGACTGCCGAACTTACGGGCGGCAGGCGTTCCGACG
GCAACCTGCTGCCGCTCTTTTTCGGGGCGGAACTGGATCACTGCCCCATGGTGGATGCCATCAAGCGTGGTACTCCCGAC
CTGCGCGAAGAAACTCTGCCGTGTGGCCGGTCGTTTTCTCTGTCCATGTATCCGGTGCGCGCAAAGGATGGCACAACAGG
TCGTGTTGTTGTGTATGTGCGTGAAACCACAATGGAAAAAAGGATGATGGTGCAGGTGCGCCAGTCTGAAAAGATGGCCA
CCGTGGGCAAACTGACTGCGGGGCTGGCACATGAAATCAACAACCCGCTGGGTGTCATTCTGTGTTATGCCGAGCTGTTG
CGGCAGAACATAAGCGATCCTCAGCAGGGGGCCGACCTTGATGTCATTGTGCGACATACCAGACAGGCGCAGCGGGTGCT
GCGTGATCTGCTGAATTTTGCCCGGCCCAAGGCCGCGGGGTCGGGACTGGCCGATGCCTGTGCCGTTGCCGGTTCCGTCA
CGGAAGTGTTTTCTGTGCAGGCCATGAAAAAAGGGGTGACACTGTCTTTGCAGTGTCCGTCCGATCTGCCGCGGGTGCGT
ATAGGTTTGAACGAACTGGAGCAGGTACTGGGCAATCTGGTGATAAACGCGCTGGATGCCTGTCCCGATGCAGACGGCGA
GGTGCTTGTGCGCATTTCCCCGCGCAGCGGCGGCATGATTGCCATCGAGGTGGCGGATAACGGGCCGGGTATTCTGCCTG
ACGATATGTCCCATGTGTTTGACCCGTTTTTCTCAACCAAGGAGACAAACGCCGGTACCGGACTGGGATTAACGGTTGTG
TACGGCATGATTACCGATGTCGGGGGCACGGTGGAAGCCGGAGCTTCTGCCGAACTGGGCGGCGCGCTGTTTACTGTGCT
GCTGCCTGCCGAAGACGGACCGGAAACGGACGGCGCGGCGTAA

Upstream 100 bases:

>100_bases
AGAATAACTCCGGCAGTGTCCGCAGACGCTGCTCTTCCGTTTTCCGGGTGCTTGATTAGCACCGGCGAAATGGCTATCAA
CCCCTTCGCCGACAGACCGC

Downstream 100 bases:

>100_bases
CGCCGGCGCGTACCGGTCAGAACAAAAGCGGAGTACGCATGTCGGAAATTGCAACACCTGCAGCCATGGTGCACAGCGGC
AGGCTGTGCCTGCTGATTGT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 840; Mature: 839

Protein sequence:

>840_residues
MAVRGASFAAEAQSEKSLPAITKGGSSGHAMHIHKPTSLQAKFLSGLAVACLTLGVLFAGGFYIHMRNVLEEEVRDKARL
IFTHVDSIQNYVRQVLRPTMYEQLPDTFVIQAMSSSFVSRSVMSRLNNGPDGTIYRRVAIDARNPEYEANERELELIDYF
RGHPESGIWRGYKNINGDRYYVMARPVRFVESCMYCHGEPADAPADLVRMYGNRGFGKEQDSIAGVDFVGLSVDGSVGRL
QRTILTYFVFFTVGAVIFFSTTNLLFKVLVVNNLKRLTNVFRRNVADAEGSALLRKLEQGDEIEELVEGMEQMGEHLYEA
RSQLQLYAENLRGMVDQRTQALSREVEARRADVALFVSLLSDMRSSTSRADLWQLALPQICRRFRARRIAYVCTMASQNY
FSWPENMGRPELPDDLVGVLTSGACVVLGNKAYIPVESSVGNAEGILCLFWDTDAEANTHDRAVLQALGRQLGTVAENMT
AIDSLMRQMNVLQTIVEGITDPLALMDSNCAVLTVNEAARKLTAELTGGRRSDGNLLPLFFGAELDHCPMVDAIKRGTPD
LREETLPCGRSFSLSMYPVRAKDGTTGRVVVYVRETTMEKRMMVQVRQSEKMATVGKLTAGLAHEINNPLGVILCYAELL
RQNISDPQQGADLDVIVRHTRQAQRVLRDLLNFARPKAAGSGLADACAVAGSVTEVFSVQAMKKGVTLSLQCPSDLPRVR
IGLNELEQVLGNLVINALDACPDADGEVLVRISPRSGGMIAIEVADNGPGILPDDMSHVFDPFFSTKETNAGTGLGLTVV
YGMITDVGGTVEAGASAELGGALFTVLLPAEDGPETDGAA

Sequences:

>Translated_840_residues
MAVRGASFAAEAQSEKSLPAITKGGSSGHAMHIHKPTSLQAKFLSGLAVACLTLGVLFAGGFYIHMRNVLEEEVRDKARL
IFTHVDSIQNYVRQVLRPTMYEQLPDTFVIQAMSSSFVSRSVMSRLNNGPDGTIYRRVAIDARNPEYEANERELELIDYF
RGHPESGIWRGYKNINGDRYYVMARPVRFVESCMYCHGEPADAPADLVRMYGNRGFGKEQDSIAGVDFVGLSVDGSVGRL
QRTILTYFVFFTVGAVIFFSTTNLLFKVLVVNNLKRLTNVFRRNVADAEGSALLRKLEQGDEIEELVEGMEQMGEHLYEA
RSQLQLYAENLRGMVDQRTQALSREVEARRADVALFVSLLSDMRSSTSRADLWQLALPQICRRFRARRIAYVCTMASQNY
FSWPENMGRPELPDDLVGVLTSGACVVLGNKAYIPVESSVGNAEGILCLFWDTDAEANTHDRAVLQALGRQLGTVAENMT
AIDSLMRQMNVLQTIVEGITDPLALMDSNCAVLTVNEAARKLTAELTGGRRSDGNLLPLFFGAELDHCPMVDAIKRGTPD
LREETLPCGRSFSLSMYPVRAKDGTTGRVVVYVRETTMEKRMMVQVRQSEKMATVGKLTAGLAHEINNPLGVILCYAELL
RQNISDPQQGADLDVIVRHTRQAQRVLRDLLNFARPKAAGSGLADACAVAGSVTEVFSVQAMKKGVTLSLQCPSDLPRVR
IGLNELEQVLGNLVINALDACPDADGEVLVRISPRSGGMIAIEVADNGPGILPDDMSHVFDPFFSTKETNAGTGLGLTVV
YGMITDVGGTVEAGASAELGGALFTVLLPAEDGPETDGAA
>Mature_839_residues
AVRGASFAAEAQSEKSLPAITKGGSSGHAMHIHKPTSLQAKFLSGLAVACLTLGVLFAGGFYIHMRNVLEEEVRDKARLI
FTHVDSIQNYVRQVLRPTMYEQLPDTFVIQAMSSSFVSRSVMSRLNNGPDGTIYRRVAIDARNPEYEANERELELIDYFR
GHPESGIWRGYKNINGDRYYVMARPVRFVESCMYCHGEPADAPADLVRMYGNRGFGKEQDSIAGVDFVGLSVDGSVGRLQ
RTILTYFVFFTVGAVIFFSTTNLLFKVLVVNNLKRLTNVFRRNVADAEGSALLRKLEQGDEIEELVEGMEQMGEHLYEAR
SQLQLYAENLRGMVDQRTQALSREVEARRADVALFVSLLSDMRSSTSRADLWQLALPQICRRFRARRIAYVCTMASQNYF
SWPENMGRPELPDDLVGVLTSGACVVLGNKAYIPVESSVGNAEGILCLFWDTDAEANTHDRAVLQALGRQLGTVAENMTA
IDSLMRQMNVLQTIVEGITDPLALMDSNCAVLTVNEAARKLTAELTGGRRSDGNLLPLFFGAELDHCPMVDAIKRGTPDL
REETLPCGRSFSLSMYPVRAKDGTTGRVVVYVRETTMEKRMMVQVRQSEKMATVGKLTAGLAHEINNPLGVILCYAELLR
QNISDPQQGADLDVIVRHTRQAQRVLRDLLNFARPKAAGSGLADACAVAGSVTEVFSVQAMKKGVTLSLQCPSDLPRVRI
GLNELEQVLGNLVINALDACPDADGEVLVRISPRSGGMIAIEVADNGPGILPDDMSHVFDPFFSTKETNAGTGLGLTVVY
GMITDVGGTVEAGASAELGGALFTVLLPAEDGPETDGAA

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=372, Percent_Identity=28.494623655914, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=31.063829787234, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790300, Length=351, Percent_Identity=29.0598290598291, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=30.3571428571429, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=246, Percent_Identity=28.4552845528455, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=28.8702928870293, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1790567, Length=335, Percent_Identity=26.5671641791045, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=302, Percent_Identity=25.1655629139073, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=225, Percent_Identity=28, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI48994928, Length=276, Percent_Identity=23.9130434782609, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91821; Mature: 91690

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRGASFAAEAQSEKSLPAITKGGSSGHAMHIHKPTSLQAKFLSGLAVACLTLGVLFAG
CCCCCCCHHHHHHCCCCCCCEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
GFYIHMRNVLEEEVRDKARLIFTHVDSIQNYVRQVLRPTMYEQLPDTFVIQAMSSSFVSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SVMSRLNNGPDGTIYRRVAIDARNPEYEANERELELIDYFRGHPESGIWRGYKNINGDRY
HHHHHHCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
YVMARPVRFVESCMYCHGEPADAPADLVRMYGNRGFGKEQDSIAGVDFVGLSVDGSVGRL
EEEECHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHH
QRTILTYFVFFTVGAVIFFSTTNLLFKVLVVNNLKRLTNVFRRNVADAEGSALLRKLEQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
DEIEELVEGMEQMGEHLYEARSQLQLYAENLRGMVDQRTQALSREVEARRADVALFVSLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDMRSSTSRADLWQLALPQICRRFRARRIAYVCTMASQNYFSWPENMGRPELPDDLVGVL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHCCCCCCCHHHHHHH
TSGACVVLGNKAYIPVESSVGNAEGILCLFWDTDAEANTHDRAVLQALGRQLGTVAENMT
HCCCEEEECCEEEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AIDSLMRQMNVLQTIVEGITDPLALMDSNCAVLTVNEAARKLTAELTGGRRSDGNLLPLF
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECHHHHHHHHHHCCCCCCCCCEEEEE
FGAELDHCPMVDAIKRGTPDLREETLPCGRSFSLSMYPVRAKDGTTGRVVVYVRETTMEK
ECCCCCCCCHHHHHHCCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCEEEEEEECHHHHH
RMMVQVRQSEKMATVGKLTAGLAHEINNPLGVILCYAELLRQNISDPQQGADLDVIVRHT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
RQAQRVLRDLLNFARPKAAGSGLADACAVAGSVTEVFSVQAMKKGVTLSLQCPSDLPRVR
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
IGLNELEQVLGNLVINALDACPDADGEVLVRISPRSGGMIAIEVADNGPGILPDDMSHVF
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHH
DPFFSTKETNAGTGLGLTVVYGMITDVGGTVEAGASAELGGALFTVLLPAEDGPETDGAA
HHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
AVRGASFAAEAQSEKSLPAITKGGSSGHAMHIHKPTSLQAKFLSGLAVACLTLGVLFAG
CCCCCCHHHHHHCCCCCCCEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
GFYIHMRNVLEEEVRDKARLIFTHVDSIQNYVRQVLRPTMYEQLPDTFVIQAMSSSFVSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
SVMSRLNNGPDGTIYRRVAIDARNPEYEANERELELIDYFRGHPESGIWRGYKNINGDRY
HHHHHHCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
YVMARPVRFVESCMYCHGEPADAPADLVRMYGNRGFGKEQDSIAGVDFVGLSVDGSVGRL
EEEECHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHH
QRTILTYFVFFTVGAVIFFSTTNLLFKVLVVNNLKRLTNVFRRNVADAEGSALLRKLEQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
DEIEELVEGMEQMGEHLYEARSQLQLYAENLRGMVDQRTQALSREVEARRADVALFVSLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDMRSSTSRADLWQLALPQICRRFRARRIAYVCTMASQNYFSWPENMGRPELPDDLVGVL
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHCCCCCCCHHHHHHH
TSGACVVLGNKAYIPVESSVGNAEGILCLFWDTDAEANTHDRAVLQALGRQLGTVAENMT
HCCCEEEECCEEEEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AIDSLMRQMNVLQTIVEGITDPLALMDSNCAVLTVNEAARKLTAELTGGRRSDGNLLPLF
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECHHHHHHHHHHCCCCCCCCCEEEEE
FGAELDHCPMVDAIKRGTPDLREETLPCGRSFSLSMYPVRAKDGTTGRVVVYVRETTMEK
ECCCCCCCCHHHHHHCCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCEEEEEEECHHHHH
RMMVQVRQSEKMATVGKLTAGLAHEINNPLGVILCYAELLRQNISDPQQGADLDVIVRHT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
RQAQRVLRDLLNFARPKAAGSGLADACAVAGSVTEVFSVQAMKKGVTLSLQCPSDLPRVR
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHH
IGLNELEQVLGNLVINALDACPDADGEVLVRISPRSGGMIAIEVADNGPGILPDDMSHVF
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCHHHHH
DPFFSTKETNAGTGLGLTVVYGMITDVGGTVEAGASAELGGALFTVLLPAEDGPETDGAA
HHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]