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The map label for this gene is rihA [H]

Identifier: 78355807

GI number: 78355807

Start: 786970

End: 788058

Strand: Direct

Name: rihA [H]

Synonym: Dde_0760

Alternate gene names: 78355807

Gene position: 786970-788058 (Clockwise)

Preceding gene: 78355806

Following gene: 78355808

Centisome position: 21.1

GC content: 62.17

Gene sequence:

>1089_bases
GTGACGGCACAGCATAACGACACCTGCGGTGCTGCGTGTCCGCCCCCTTTGCGCAGGGCAGAAGCTCCGGTAAAGGTGCT
GCTGGACATTGACAACGCCATGGGGTTGCCCGTGCGCGATGCCGATGACGGCGTGGCTCTGGCTCTGGCGCTGTGGTCGC
CGGAATTCGAGCTGACAGCCTGCACCACCTGTTCCGGAAACTGCCGGGCATCGGCTTCGGCGCAGAACACGCTGCGCATG
CTGGAACTGGCCGGTGCAGACGCGGTACCGGTGGCAGCCGGCACCGATACACCGCTGGGGGGTGAGGACAGAGCGCGGCA
TCATGCCTTTCTGGACGCCAAAGCTTCAGGAGCCGGAGCCTCGCTGTGGGACGATGTGTCGCTGCCGGCGCCTTCTGCCC
GTCAGGCCTCTGCTCCTGCCTGCAGGCTTATCATAGAAACGGTGCGCCGCCACCCGCACGAGGTGGTGCTGGTAATGGAA
GGCGCATTGACTAATCTGGCTCTTGCCCTGCGACATGCCTCTGACATTGCTCCGCTTATCGGCGCGGTTGTGCATATGGG
CGGTGTGTTTGCGCCCCGCTGTCCCGAAGAAATGGCACCGCAGTGGAAAACCCCCGACATACCTGAATATGTGTGGCGGC
ATGCGCTGCGTTTCAATACATGGTATGACCCGCAGGCCACCGAGGAAGTGGTACGGGCGGGGCTGCCGCTGTGCTTTGTG
CCTGTCAATGTGACCAGCCGGACATGTCTTTCTTCGCATCAGATCGCGCAGATGCGCACCGCGGACGATCCGCTGCGGTG
TTTTGTGCGCCGGACGCTGCTGCCCTGGGCGCGCTGGAGCGAACAGGTCAGAGGTCTGGACGGCGCACACATGCATGATG
CGCTGGCGCTTGCGGTGGCCGCCATGCCGCACCTGTGCAGCTGGAAGCCGTTCTGCTTTGATGTTCAGGCATTTCGGGAT
GGTAGGGATTTTCTACTGCCTTTTGGTGACAAACCCTACCATCGGGTGTGGGTGGCCACTGCGGTGGACGCGGCTGCTTT
TCATGCATGGCTGCTTGCGACCATGGGTATAGATGTATCGGCTTTGTAA

Upstream 100 bases:

>100_bases
CTGAAAAACTGGCCGAACACGCCGTGCCGGAAATTCCCGCCCTCTGGCTGGAAGCCATTGAAGAAGGCTGGGACAGACAT
GTGCTGCGGCAGAACCGGCA

Downstream 100 bases:

>100_bases
TACAAGTGTATACTTTTCAACATTTTGTTTTCTGGCATGGGAATGTTCAATGTTTTTGCGCCTCGTTTTACCCCAAGTGC
ACGGCACCCAAGGAGAAAAA

Product: inosine-uridine nucleoside N-ribohydrolase-like

Products: D-ribose; purine

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTAQHNDTCGAACPPPLRRAEAPVKVLLDIDNAMGLPVRDADDGVALALALWSPEFELTACTTCSGNCRASASAQNTLRM
LELAGADAVPVAAGTDTPLGGEDRARHHAFLDAKASGAGASLWDDVSLPAPSARQASAPACRLIIETVRRHPHEVVLVME
GALTNLALALRHASDIAPLIGAVVHMGGVFAPRCPEEMAPQWKTPDIPEYVWRHALRFNTWYDPQATEEVVRAGLPLCFV
PVNVTSRTCLSSHQIAQMRTADDPLRCFVRRTLLPWARWSEQVRGLDGAHMHDALALAVAAMPHLCSWKPFCFDVQAFRD
GRDFLLPFGDKPYHRVWVATAVDAAAFHAWLLATMGIDVSAL

Sequences:

>Translated_362_residues
MTAQHNDTCGAACPPPLRRAEAPVKVLLDIDNAMGLPVRDADDGVALALALWSPEFELTACTTCSGNCRASASAQNTLRM
LELAGADAVPVAAGTDTPLGGEDRARHHAFLDAKASGAGASLWDDVSLPAPSARQASAPACRLIIETVRRHPHEVVLVME
GALTNLALALRHASDIAPLIGAVVHMGGVFAPRCPEEMAPQWKTPDIPEYVWRHALRFNTWYDPQATEEVVRAGLPLCFV
PVNVTSRTCLSSHQIAQMRTADDPLRCFVRRTLLPWARWSEQVRGLDGAHMHDALALAVAAMPHLCSWKPFCFDVQAFRD
GRDFLLPFGDKPYHRVWVATAVDAAAFHAWLLATMGIDVSAL
>Mature_361_residues
TAQHNDTCGAACPPPLRRAEAPVKVLLDIDNAMGLPVRDADDGVALALALWSPEFELTACTTCSGNCRASASAQNTLRML
ELAGADAVPVAAGTDTPLGGEDRARHHAFLDAKASGAGASLWDDVSLPAPSARQASAPACRLIIETVRRHPHEVVLVMEG
ALTNLALALRHASDIAPLIGAVVHMGGVFAPRCPEEMAPQWKTPDIPEYVWRHALRFNTWYDPQATEEVVRAGLPLCFVP
VNVTSRTCLSSHQIAQMRTADDPLRCFVRRTLLPWARWSEQVRGLDGAHMHDALALAVAAMPHLCSWKPFCFDVQAFRDG
RDFLLPFGDKPYHRVWVATAVDAAAFHAWLLATMGIDVSAL

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=267, Percent_Identity=28.0898876404494, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788486, Length=280, Percent_Identity=25.7142857142857, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786213, Length=317, Percent_Identity=27.1293375394322, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022975 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: 3.2.2.1

Molecular weight: Translated: 39196; Mature: 39065

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQHNDTCGAACPPPLRRAEAPVKVLLDIDNAMGLPVRDADDGVALALALWSPEFELTA
CCCCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCEEEE
CTTCSGNCRASASAQNTLRMLELAGADAVPVAAGTDTPLGGEDRARHHAFLDAKASGAGA
EEECCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHEEECCCCCCCC
SLWDDVSLPAPSARQASAPACRLIIETVRRHPHEVVLVMEGALTNLALALRHASDIAPLI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
GAVVHMGGVFAPRCPEEMAPQWKTPDIPEYVWRHALRFNTWYDPQATEEVVRAGLPLCFV
HHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEE
PVNVTSRTCLSSHQIAQMRTADDPLRCFVRRTLLPWARWSEQVRGLDGAHMHDALALAVA
ECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHH
AMPHLCSWKPFCFDVQAFRDGRDFLLPFGDKPYHRVWVATAVDAAAFHAWLLATMGIDVS
HHHHHCCCCCCEEEHHHHHCCCCEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCC
AL
CC
>Mature Secondary Structure 
TAQHNDTCGAACPPPLRRAEAPVKVLLDIDNAMGLPVRDADDGVALALALWSPEFELTA
CCCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCEEEE
CTTCSGNCRASASAQNTLRMLELAGADAVPVAAGTDTPLGGEDRARHHAFLDAKASGAGA
EEECCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHEEECCCCCCCC
SLWDDVSLPAPSARQASAPACRLIIETVRRHPHEVVLVMEGALTNLALALRHASDIAPLI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
GAVVHMGGVFAPRCPEEMAPQWKTPDIPEYVWRHALRFNTWYDPQATEEVVRAGLPLCFV
HHHHHHCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEE
PVNVTSRTCLSSHQIAQMRTADDPLRCFVRRTLLPWARWSEQVRGLDGAHMHDALALAVA
ECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHH
AMPHLCSWKPFCFDVQAFRDGRDFLLPFGDKPYHRVWVATAVDAAAFHAWLLATMGIDVS
HHHHHCCCCCCEEEHHHHHCCCCEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCC
AL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-D-ribosylpurine; H2O

Specific reaction: an N-D-ribosylpurine + H2O = D-ribose + a purine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA