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The map label for this gene is zraR [H]

Identifier: 78355744

GI number: 78355744

Start: 711457

End: 714015

Strand: Direct

Name: zraR [H]

Synonym: Dde_0697

Alternate gene names: 78355744

Gene position: 711457-714015 (Clockwise)

Preceding gene: 78355738

Following gene: 78355748

Centisome position: 19.07

GC content: 60.84

Gene sequence:

>2559_bases
ATGTTTCTGGAAAAAAAGCCTATCTCTCAGATTCTTCTGTTATTCACTGCACCTTTGCTGCTTTTGCTGGTGGGGTTGCA
GGGCGGCGTTGCGTTGTATTTTTCGTTCGATGCGCTGCAGATGGCTCTGGGACGGGCAGTACAGACGCGCACCATGGCCG
TTTCGTACGAGATAAGCAGCTATCTGCAGAAAGTACGGTATAATGCCCTGCTGCTGGCTGACTTTGCCGCAACTGATGAA
GGGCTGGGCGGCTATCTGAACAGAGTGGGCGGACTGGTGGAAAGCAACGCCGTGGAAGTGGTTGTGGTGCTGGCCGACGG
TCGCCGGGCGCACTATGTGCGCAGTGGCGAGCATGCTTCCGGTGTCTGGCGTGATTCTGGCGAGATAGGCGGACGTCCGG
ACGGATACGATTTTTTATCGAGAGATATTAAAGGATTAAGGGTTGGCGAGGTTGCAGTTTCCCGTGTGGTTCCTGCGCGG
GTACTTGTGCAGGGCCCTTTTGAAAGCGAGCTGACCAGCATGCCCGTTATCCGTTTTTCCACACCGGTGAAAGGGCCTGA
CGGCGGGGTGGGCGGTGCTCTTTCGCTGCTGGTGGCTGCCGATCATCTGGGTACGATTCTCACATACCTGCAGTCCGACG
ATTCGCCGCTGCAGTCTTTTCAGCGGCGGCCCGCAAGGCGGTTCAGCTATTTTGCCGACCCCCGCGGATGGATTTTGTAC
GAATCTGCCAGCGAACAGAACAAAACCTGCCAGCCGGTGCAGTCCCGTCAGGATGTGCGCGGCACGCTGGGACTGCCGGG
CATGGCCGGTGCGTTTCTGCCGTCCGACGAATACCGCAGCTTCTGGAGCGGTATCGCCGGAGCCAGAAAAAAAGAACCCT
CACTTACCCAGCACTGGGAGCACGGGGACGGGCTGTTTTTTCCCACCATCATGATGGAGGCGGGGGCACCTGTTCTGTAC
CGCATCAGCGACGATGCCCCGCCGCAGGTGTGGGGGGTGGCCTTCAGTGTTGACCGCAGTCTGCTGCCGCATGTGCTGGG
CAGCAGGCAGGCGGCCATTCTGTGTGCCGTGGGCGTGGCGGTGCTGGCTGTAAGCGCGCTGGTGCTGTATTTTGTCGGGC
GCTTTTGCGGTGCCCCCCTGCTGCGTCTTGCCCGCAGGGTGGAATCTGCCGCTCTGCAGCCGTCGCCCGAGCCGGTGGAA
GAGGTTTTCAGGGGCTACGAGGTGCAGACATTGCAACGGGCCGTCAATGCCATGATACGGACCATGGGGTTGCAGGCTGC
CGAGATAGAGGAAAAAACACGCAAGCTCACACACTATGCCAATCTGCAACAGGTCGACTTTGCAGAGGAACTCAGTCCGG
CACAGGAGTTTGAACATTCCGCGCTGGGGGTACTTAAAGGCTCCAGCGAGTCCATCCGGCGGCTCAAGGCCGACATAGGC
AGGGCCGCACAGGTGGATGCCGATATTCTGATTGAAGGCGAAACCGGAACCGGCAAACAGCTGACAGCCGAAGCCGTGCA
TAAAGCCAGCAGGCGCTGCAACGGTCCGCTGGTACCCATAAATTGCGGCGCACTGGATGAAAATCTGCTGCTGGACGCGC
TGTTCGGTCATCGCAAGGGTGCTTATTCGGGGGCGGAGACAGACAGAGACGGGGCGTTTGTGCATGCCCACGGCGGCACA
TTGTTTCTGGACGAAATCCAGTCAGCTTCCTCCAAGGTGCAGCAGGCGCTGCTGCGGGCCATCGCCAGCCGCCGGATACG
GCCTTTGGGAGCCGATGCGGAGTATGCGGTGGATGTGCGGGTTATCTGCGCCACCAACGTTGACCTGCAGGAGGAGATAG
CCGCCGGCAGGTTCCGGCAGGACCTTTACTACCGTATCAAGGTGCTTTCGCTGCGCACTCCCCCGCTGCGTGAGCATCTG
GAAAGCATTCCGGCACTGACGGCGTTTTTTCTGGACCGTGCGCGTGAAGTGCTGGGGCTGCCGCATCTGGCACTGACCAA
AGGAGCCATGCAGACGCTGATGCAGTACTCATGGCCCGGCAATGTGCGTGAGCTGGAAAACTGCATTCTGCAGGCCGCCG
TCAATGCGCGCGAGGGGCTGATACATTCTGCGGATATCCCTGTGGGCAGAGCTGGAGAGCCGGCCGCCGGGGCATCGCAG
TGGCGGCCTTTTGCCGCCGGGCAGGGCCACGGGGCCGATGGTGAGCGCCGCGATGCCGGAAGAGCTTCCGTTCCCGCGGG
GGGGCAGGGTGATGAGCCGTTTTCTGCCACAGGACAGGCAATGCCGGAAGCGCCGCCTGCCCGCGGTCCTGTGCGGGGCG
GGCAGGTAGTGCCGGCAGGTGTGAAAGATGCAGGGCTGCAGGGGCTCAATGAGCGTCAGATAAAGGCTCTGGAGCATCTG
CGAACGCACCGGAGCATGACACGGCGTGAATACATGGCATTGTTCACATATGATATTTCTGACCGCACGGCAGGCAGAGA
CCTGCAGGGGCTGTTCGAACGGGGGCTGGTGACCAGAAGCGGAGCCGGACCGGCCACTGCGTACCGGCTGGCTGTGTAG

Upstream 100 bases:

>100_bases
AAAAATATTGAGTCGGAATGCGGCAGGTGCTATGGCTTGATGTGTCTTCTTATATTCTGCGACGTATGTCCTGAAAGGCC
TGCTGGCGGCGAGGTTGTCC

Downstream 100 bases:

>100_bases
CGGGTCAGTCCAGTGTTTTGCTGTATCTTTTGAGTGCCAGCACCACGGCAGCCAGCCAGAATACGAGTATGGGCCACAGC
GAAGGCCATGAAGCCTCAAA

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 852; Mature: 852

Protein sequence:

>852_residues
MFLEKKPISQILLLFTAPLLLLLVGLQGGVALYFSFDALQMALGRAVQTRTMAVSYEISSYLQKVRYNALLLADFAATDE
GLGGYLNRVGGLVESNAVEVVVVLADGRRAHYVRSGEHASGVWRDSGEIGGRPDGYDFLSRDIKGLRVGEVAVSRVVPAR
VLVQGPFESELTSMPVIRFSTPVKGPDGGVGGALSLLVAADHLGTILTYLQSDDSPLQSFQRRPARRFSYFADPRGWILY
ESASEQNKTCQPVQSRQDVRGTLGLPGMAGAFLPSDEYRSFWSGIAGARKKEPSLTQHWEHGDGLFFPTIMMEAGAPVLY
RISDDAPPQVWGVAFSVDRSLLPHVLGSRQAAILCAVGVAVLAVSALVLYFVGRFCGAPLLRLARRVESAALQPSPEPVE
EVFRGYEVQTLQRAVNAMIRTMGLQAAEIEEKTRKLTHYANLQQVDFAEELSPAQEFEHSALGVLKGSSESIRRLKADIG
RAAQVDADILIEGETGTGKQLTAEAVHKASRRCNGPLVPINCGALDENLLLDALFGHRKGAYSGAETDRDGAFVHAHGGT
LFLDEIQSASSKVQQALLRAIASRRIRPLGADAEYAVDVRVICATNVDLQEEIAAGRFRQDLYYRIKVLSLRTPPLREHL
ESIPALTAFFLDRAREVLGLPHLALTKGAMQTLMQYSWPGNVRELENCILQAAVNAREGLIHSADIPVGRAGEPAAGASQ
WRPFAAGQGHGADGERRDAGRASVPAGGQGDEPFSATGQAMPEAPPARGPVRGGQVVPAGVKDAGLQGLNERQIKALEHL
RTHRSMTRREYMALFTYDISDRTAGRDLQGLFERGLVTRSGAGPATAYRLAV

Sequences:

>Translated_852_residues
MFLEKKPISQILLLFTAPLLLLLVGLQGGVALYFSFDALQMALGRAVQTRTMAVSYEISSYLQKVRYNALLLADFAATDE
GLGGYLNRVGGLVESNAVEVVVVLADGRRAHYVRSGEHASGVWRDSGEIGGRPDGYDFLSRDIKGLRVGEVAVSRVVPAR
VLVQGPFESELTSMPVIRFSTPVKGPDGGVGGALSLLVAADHLGTILTYLQSDDSPLQSFQRRPARRFSYFADPRGWILY
ESASEQNKTCQPVQSRQDVRGTLGLPGMAGAFLPSDEYRSFWSGIAGARKKEPSLTQHWEHGDGLFFPTIMMEAGAPVLY
RISDDAPPQVWGVAFSVDRSLLPHVLGSRQAAILCAVGVAVLAVSALVLYFVGRFCGAPLLRLARRVESAALQPSPEPVE
EVFRGYEVQTLQRAVNAMIRTMGLQAAEIEEKTRKLTHYANLQQVDFAEELSPAQEFEHSALGVLKGSSESIRRLKADIG
RAAQVDADILIEGETGTGKQLTAEAVHKASRRCNGPLVPINCGALDENLLLDALFGHRKGAYSGAETDRDGAFVHAHGGT
LFLDEIQSASSKVQQALLRAIASRRIRPLGADAEYAVDVRVICATNVDLQEEIAAGRFRQDLYYRIKVLSLRTPPLREHL
ESIPALTAFFLDRAREVLGLPHLALTKGAMQTLMQYSWPGNVRELENCILQAAVNAREGLIHSADIPVGRAGEPAAGASQ
WRPFAAGQGHGADGERRDAGRASVPAGGQGDEPFSATGQAMPEAPPARGPVRGGQVVPAGVKDAGLQGLNERQIKALEHL
RTHRSMTRREYMALFTYDISDRTAGRDLQGLFERGLVTRSGAGPATAYRLAV
>Mature_852_residues
MFLEKKPISQILLLFTAPLLLLLVGLQGGVALYFSFDALQMALGRAVQTRTMAVSYEISSYLQKVRYNALLLADFAATDE
GLGGYLNRVGGLVESNAVEVVVVLADGRRAHYVRSGEHASGVWRDSGEIGGRPDGYDFLSRDIKGLRVGEVAVSRVVPAR
VLVQGPFESELTSMPVIRFSTPVKGPDGGVGGALSLLVAADHLGTILTYLQSDDSPLQSFQRRPARRFSYFADPRGWILY
ESASEQNKTCQPVQSRQDVRGTLGLPGMAGAFLPSDEYRSFWSGIAGARKKEPSLTQHWEHGDGLFFPTIMMEAGAPVLY
RISDDAPPQVWGVAFSVDRSLLPHVLGSRQAAILCAVGVAVLAVSALVLYFVGRFCGAPLLRLARRVESAALQPSPEPVE
EVFRGYEVQTLQRAVNAMIRTMGLQAAEIEEKTRKLTHYANLQQVDFAEELSPAQEFEHSALGVLKGSSESIRRLKADIG
RAAQVDADILIEGETGTGKQLTAEAVHKASRRCNGPLVPINCGALDENLLLDALFGHRKGAYSGAETDRDGAFVHAHGGT
LFLDEIQSASSKVQQALLRAIASRRIRPLGADAEYAVDVRVICATNVDLQEEIAAGRFRQDLYYRIKVLSLRTPPLREHL
ESIPALTAFFLDRAREVLGLPHLALTKGAMQTLMQYSWPGNVRELENCILQAAVNAREGLIHSADIPVGRAGEPAAGASQ
WRPFAAGQGHGADGERRDAGRASVPAGGQGDEPFSATGQAMPEAPPARGPVRGGQVVPAGVKDAGLQGLNERQIKALEHL
RTHRSMTRREYMALFTYDISDRTAGRDLQGLFERGLVTRSGAGPATAYRLAV

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=248, Percent_Identity=45.9677419354839, Blast_Score=217, Evalue=3e-57,
Organism=Escherichia coli, GI87082152, Length=244, Percent_Identity=46.7213114754098, Blast_Score=203, Evalue=4e-53,
Organism=Escherichia coli, GI1788905, Length=234, Percent_Identity=45.2991452991453, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1788550, Length=279, Percent_Identity=38.7096774193548, Blast_Score=192, Evalue=8e-50,
Organism=Escherichia coli, GI1789233, Length=233, Percent_Identity=42.4892703862661, Blast_Score=185, Evalue=1e-47,
Organism=Escherichia coli, GI87082117, Length=243, Percent_Identity=41.9753086419753, Blast_Score=182, Evalue=8e-47,
Organism=Escherichia coli, GI1790299, Length=274, Percent_Identity=37.5912408759124, Blast_Score=180, Evalue=4e-46,
Organism=Escherichia coli, GI1789087, Length=238, Percent_Identity=41.1764705882353, Blast_Score=176, Evalue=5e-45,
Organism=Escherichia coli, GI1786524, Length=246, Percent_Identity=40.2439024390244, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI87081872, Length=226, Percent_Identity=40.7079646017699, Blast_Score=172, Evalue=1e-43,
Organism=Escherichia coli, GI1787583, Length=233, Percent_Identity=39.9141630901288, Blast_Score=166, Evalue=6e-42,
Organism=Escherichia coli, GI1789828, Length=301, Percent_Identity=31.5614617940199, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87081858, Length=235, Percent_Identity=34.468085106383, Blast_Score=118, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 92154; Mature: 92154

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLEKKPISQILLLFTAPLLLLLVGLQGGVALYFSFDALQMALGRAVQTRTMAVSYEISS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHEEEHHHHHH
YLQKVRYNALLLADFAATDEGLGGYLNRVGGLVESNAVEVVVVLADGRRAHYVRSGEHAS
HHHHHHHCEEEEEEHHCCCCCHHHHHHHHCCHHCCCCEEEEEEEECCCEEEEEECCCCCC
GVWRDSGEIGGRPDGYDFLSRDIKGLRVGEVAVSRVVPARVLVQGPFESELTSMPVIRFS
CCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCHHHEEECCCHHHHHCCCEEEEC
TPVKGPDGGVGGALSLLVAADHLGTILTYLQSDDSPLQSFQRRPARRFSYFADPRGWILY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHCCCCCCEEEE
ESASEQNKTCQPVQSRQDVRGTLGLPGMAGAFLPSDEYRSFWSGIAGARKKEPSLTQHWE
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCC
HGDGLFFPTIMMEAGAPVLYRISDDAPPQVWGVAFSVDRSLLPHVLGSRQAAILCAVGVA
CCCCEEHHHHHHHCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHH
VLAVSALVLYFVGRFCGAPLLRLARRVESAALQPSPEPVEEVFRGYEVQTLQRAVNAMIR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHH
TMGLQAAEIEEKTRKLTHYANLQQVDFAEELSPAQEFEHSALGVLKGSSESIRRLKADIG
HHCCCHHHHHHHHHHHHHHCCCHHHCCHHHCCHHHHHHHHHHHEECCCHHHHHHHHHHHC
RAAQVDADILIEGETGTGKQLTAEAVHKASRRCNGPLVPINCGALDENLLLDALFGHRKG
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCC
AYSGAETDRDGAFVHAHGGTLFLDEIQSASSKVQQALLRAIASRRIRPLGADAEYAVDVR
CCCCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
VICATNVDLQEEIAAGRFRQDLYYRIKVLSLRTPPLREHLESIPALTAFFLDRAREVLGL
EEEECCCCHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PHLALTKGAMQTLMQYSWPGNVRELENCILQAAVNAREGLIHSADIPVGRAGEPAAGASQ
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCHHH
WRPFAAGQGHGADGERRDAGRASVPAGGQGDEPFSATGQAMPEAPPARGPVRGGQVVPAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCC
VKDAGLQGLNERQIKALEHLRTHRSMTRREYMALFTYDISDRTAGRDLQGLFERGLVTRS
CCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHCCCEECC
GAGPATAYRLAV
CCCCCCEEEECC
>Mature Secondary Structure
MFLEKKPISQILLLFTAPLLLLLVGLQGGVALYFSFDALQMALGRAVQTRTMAVSYEISS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHEEEHHHHHH
YLQKVRYNALLLADFAATDEGLGGYLNRVGGLVESNAVEVVVVLADGRRAHYVRSGEHAS
HHHHHHHCEEEEEEHHCCCCCHHHHHHHHCCHHCCCCEEEEEEEECCCEEEEEECCCCCC
GVWRDSGEIGGRPDGYDFLSRDIKGLRVGEVAVSRVVPARVLVQGPFESELTSMPVIRFS
CCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCHHHEEECCCHHHHHCCCEEEEC
TPVKGPDGGVGGALSLLVAADHLGTILTYLQSDDSPLQSFQRRPARRFSYFADPRGWILY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHCCCCCCEEEE
ESASEQNKTCQPVQSRQDVRGTLGLPGMAGAFLPSDEYRSFWSGIAGARKKEPSLTQHWE
CCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCC
HGDGLFFPTIMMEAGAPVLYRISDDAPPQVWGVAFSVDRSLLPHVLGSRQAAILCAVGVA
CCCCEEHHHHHHHCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHH
VLAVSALVLYFVGRFCGAPLLRLARRVESAALQPSPEPVEEVFRGYEVQTLQRAVNAMIR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHH
TMGLQAAEIEEKTRKLTHYANLQQVDFAEELSPAQEFEHSALGVLKGSSESIRRLKADIG
HHCCCHHHHHHHHHHHHHHCCCHHHCCHHHCCHHHHHHHHHHHEECCCHHHHHHHHHHHC
RAAQVDADILIEGETGTGKQLTAEAVHKASRRCNGPLVPINCGALDENLLLDALFGHRKG
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCC
AYSGAETDRDGAFVHAHGGTLFLDEIQSASSKVQQALLRAIASRRIRPLGADAEYAVDVR
CCCCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
VICATNVDLQEEIAAGRFRQDLYYRIKVLSLRTPPLREHLESIPALTAFFLDRAREVLGL
EEEECCCCHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PHLALTKGAMQTLMQYSWPGNVRELENCILQAAVNAREGLIHSADIPVGRAGEPAAGASQ
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCHHH
WRPFAAGQGHGADGERRDAGRASVPAGGQGDEPFSATGQAMPEAPPARGPVRGGQVVPAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCC
VKDAGLQGLNERQIKALEHLRTHRSMTRREYMALFTYDISDRTAGRDLQGLFERGLVTRS
CCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHCCCEECC
GAGPATAYRLAV
CCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]