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The map label for this gene is paaK [H]

Identifier: 78355587

GI number: 78355587

Start: 551514

End: 552779

Strand: Direct

Name: paaK [H]

Synonym: Dde_0540

Alternate gene names: 78355587

Gene position: 551514-552779 (Clockwise)

Preceding gene: 78355586

Following gene: 78355588

Centisome position: 14.78

GC content: 55.69

Gene sequence:

>1266_bases
ATGACCCGTAAAGACAGAACAGAAGGCATATACAGCCGTCGTGAAGTGCTGGACGAGAGCGAGCGCAAGCAATATTACCT
CATTCAACTCAAGGACCTGCTGTCCTATGCGTACCGCTACTCCGAAGACGTGAAAAAGCGTTTCGACCGTGCGCAGTTCA
ATGTCGAAAAATTCAAGACGCTGACCGACCTGAAGCATATTCCCATTCTGAAAAAGAAGGAGCTCATCTTTCTGCAGTCC
ATGGGGCCGCGGCTGGGCGGACTGCTGACCAAAGACCTCGGCGAACTCAAGCGCGTGTTCCTTTCGCCCGGGCCCATATT
CGACCCCGAAGACCGTCAGGACGATTACTGGGGATACACCGAGGCTTTTTATTCCGCAGGGTTCCGTTCGGGCGATGTTT
CGCAGATAACCTTCAACTATCATCTGGCGCCTGCCGGTCTGATGTTTGAAGAGCCGCTGCGCAATCTCGGCTGCGCCACC
ATACCAGCCGGACCGGGCAACGCCGCCACCCAGCTGGAAATCATGCAGAAGCTGCGCGTGACCGGCTATGTGGGCACCCC
CAGCTATCTGATGCACCTTGCCCAGAAAGCCGAGGAAAAAGGCCTGAATCTGCGTAAGGATCTTTTCCTTGAAGTGGCGT
TTGTCACGGGTGAAAAGTTTTCTGAAAAAATGCGCAACCAGCTTGAGAAAAAATTCGATCTGGTCATGCGGCAGGGGTAC
GGCACGGCCGACGTGGGCTGTGTGGGCTACGAGTGTTATCACAAGACCGGTCTGCACATAGCCAACCGCGCCTATGTTGA
AATATGCCACCCTGATACCGGCATTCCGCTGAAAGACGGTGAAGTGGGTGAAATTGTCGTCACGGCGTTTAACAAGACGT
ATCCGCTTATCCGTCTTGCCACGGGCGATCTTTCATACATTGACCGTTCGCCCTGCCCCTGCGGCCGGACAAGCCCGCGT
CTGGGCAACATCGTCGGCCGTGTGGACACCACCGCCCGCATCAAGGGCATGTTCGTGTATCCGCATCAGGTGGAACAGGT
CATCTCGCGTTTTGAAGATATCAAGCGCTGGCAGATAGAAGTGACCAACCCCGGCGGTATCGACGAAATGACTCTGTTTA
TTGAGGCGAGCAACTTCAAGCGGGAAGACGAACTGCTGCACGCGTTCCGCGAGCGCATCAAACTGCGGCCCGAGCTCAAG
GTGCTTGCACCCGGTTCGCTGCCTCCGCAGATCCGTCCCATCGAGGACAAGAGAGTATGGGACTAG

Upstream 100 bases:

>100_bases
AATGTATGGTAAAAAATAATTTTTCTTGATTTATGCTTTGGGATGCCGTATACTGATTAACTACCATTGTGTAGGCTTAT
TTCATCTCTGGAGCAGAAGC

Downstream 100 bases:

>100_bases
CCTTCAGGCTTGCCATACTCGGCCTGCTGATTCTGACGGCAGGCGGGTGCGCCGTTATGCGCCCGCCTGCCTCTTTCCGG
CCGCCGGAGCGTGAAGAACA

Product: phenylacetate-coenzyme A ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTRKDRTEGIYSRREVLDESERKQYYLIQLKDLLSYAYRYSEDVKKRFDRAQFNVEKFKTLTDLKHIPILKKKELIFLQS
MGPRLGGLLTKDLGELKRVFLSPGPIFDPEDRQDDYWGYTEAFYSAGFRSGDVSQITFNYHLAPAGLMFEEPLRNLGCAT
IPAGPGNAATQLEIMQKLRVTGYVGTPSYLMHLAQKAEEKGLNLRKDLFLEVAFVTGEKFSEKMRNQLEKKFDLVMRQGY
GTADVGCVGYECYHKTGLHIANRAYVEICHPDTGIPLKDGEVGEIVVTAFNKTYPLIRLATGDLSYIDRSPCPCGRTSPR
LGNIVGRVDTTARIKGMFVYPHQVEQVISRFEDIKRWQIEVTNPGGIDEMTLFIEASNFKREDELLHAFRERIKLRPELK
VLAPGSLPPQIRPIEDKRVWD

Sequences:

>Translated_421_residues
MTRKDRTEGIYSRREVLDESERKQYYLIQLKDLLSYAYRYSEDVKKRFDRAQFNVEKFKTLTDLKHIPILKKKELIFLQS
MGPRLGGLLTKDLGELKRVFLSPGPIFDPEDRQDDYWGYTEAFYSAGFRSGDVSQITFNYHLAPAGLMFEEPLRNLGCAT
IPAGPGNAATQLEIMQKLRVTGYVGTPSYLMHLAQKAEEKGLNLRKDLFLEVAFVTGEKFSEKMRNQLEKKFDLVMRQGY
GTADVGCVGYECYHKTGLHIANRAYVEICHPDTGIPLKDGEVGEIVVTAFNKTYPLIRLATGDLSYIDRSPCPCGRTSPR
LGNIVGRVDTTARIKGMFVYPHQVEQVISRFEDIKRWQIEVTNPGGIDEMTLFIEASNFKREDELLHAFRERIKLRPELK
VLAPGSLPPQIRPIEDKRVWD
>Mature_420_residues
TRKDRTEGIYSRREVLDESERKQYYLIQLKDLLSYAYRYSEDVKKRFDRAQFNVEKFKTLTDLKHIPILKKKELIFLQSM
GPRLGGLLTKDLGELKRVFLSPGPIFDPEDRQDDYWGYTEAFYSAGFRSGDVSQITFNYHLAPAGLMFEEPLRNLGCATI
PAGPGNAATQLEIMQKLRVTGYVGTPSYLMHLAQKAEEKGLNLRKDLFLEVAFVTGEKFSEKMRNQLEKKFDLVMRQGYG
TADVGCVGYECYHKTGLHIANRAYVEICHPDTGIPLKDGEVGEIVVTAFNKTYPLIRLATGDLSYIDRSPCPCGRTSPRL
GNIVGRVDTTARIKGMFVYPHQVEQVISRFEDIKRWQIEVTNPGGIDEMTLFIEASNFKREDELLHAFRERIKLRPELKV
LAPGSLPPQIRPIEDKRVWD

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=403, Percent_Identity=26.5508684863524, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48236; Mature: 48105

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKDRTEGIYSRREVLDESERKQYYLIQLKDLLSYAYRYSEDVKKRFDRAQFNVEKFKT
CCCCCHHHHHHHHHHHHCHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LTDLKHIPILKKKELIFLQSMGPRLGGLLTKDLGELKRVFLSPGPIFDPEDRQDDYWGYT
HHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
EAFYSAGFRSGDVSQITFNYHLAPAGLMFEEPLRNLGCATIPAGPGNAATQLEIMQKLRV
HHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHH
TGYVGTPSYLMHLAQKAEEKGLNLRKDLFLEVAFVTGEKFSEKMRNQLEKKFDLVMRQGY
EECCCCHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
GTADVGCVGYECYHKTGLHIANRAYVEICHPDTGIPLKDGEVGEIVVTAFNKTYPLIRLA
CCCCCCEECHHHHHHCCCEEECEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEE
TGDLSYIDRSPCPCGRTSPRLGNIVGRVDTTARIKGMFVYPHQVEQVISRFEDIKRWQIE
CCCHHHCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHCCEEEEE
VTNPGGIDEMTLFIEASNFKREDELLHAFRERIKLRPELKVLAPGSLPPQIRPIEDKRVW
ECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC
D
C
>Mature Secondary Structure 
TRKDRTEGIYSRREVLDESERKQYYLIQLKDLLSYAYRYSEDVKKRFDRAQFNVEKFKT
CCCCHHHHHHHHHHHHCHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LTDLKHIPILKKKELIFLQSMGPRLGGLLTKDLGELKRVFLSPGPIFDPEDRQDDYWGYT
HHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
EAFYSAGFRSGDVSQITFNYHLAPAGLMFEEPLRNLGCATIPAGPGNAATQLEIMQKLRV
HHHHHCCCCCCCCEEEEEEEEECCCCHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHH
TGYVGTPSYLMHLAQKAEEKGLNLRKDLFLEVAFVTGEKFSEKMRNQLEKKFDLVMRQGY
EECCCCHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
GTADVGCVGYECYHKTGLHIANRAYVEICHPDTGIPLKDGEVGEIVVTAFNKTYPLIRLA
CCCCCCEECHHHHHHCCCEEECEEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEE
TGDLSYIDRSPCPCGRTSPRLGNIVGRVDTTARIKGMFVYPHQVEQVISRFEDIKRWQIE
CCCHHHCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHCCEEEEE
VTNPGGIDEMTLFIEASNFKREDELLHAFRERIKLRPELKVLAPGSLPPQIRPIEDKRVW
ECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]