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The map label for this gene is yciR [C]

Identifier: 78355579

GI number: 78355579

Start: 538642

End: 540789

Strand: Direct

Name: yciR [C]

Synonym: Dde_0532

Alternate gene names: 78355579

Gene position: 538642-540789 (Clockwise)

Preceding gene: 78355578

Following gene: 78355581

Centisome position: 14.44

GC content: 57.08

Gene sequence:

>2148_bases
ATGCAGCACGATCCGCCCAGAGTTCTGTCGATAGACGATGATAGAAATGTCCGTGAAAATATCGTCGCCTATCTGGAAGA
CAGCGGTTTTGATGTGGTCGAAGCCGAAAACGGCCGTCAGGGGCTGGAGGAGTTCGAAAGGTCCGCTCCGGACATCGTGC
TTGTTGACCTGCGCATGCCGGTGATGGACGGCATGCAGTTTCTGGCCGAGCTGCGCAAGATTTCCAAACGCATTCCCGTT
ATTGTGGTTTCCGGCGTGGGTGTGCTTGAAGAAGCTGTGGAGGCTTTGCGGCATGGCGCGTGGGATTATGTAACCAAGCC
CATCAGTGACATGGTGGTGCTGGAACACGCCGTGAACAAAGCGCTGGAGCGCGCCCGCCTGCTGGATGAGCGCGACAGGT
ACCGCGAGCGGCTGGAACAGGAAGTGGCGGAACGTACCGGAGAGCTGCGCGAATCCAACGAGCGTCTGCTGGAGTTTCAG
AGTCTGCTGCAGGAAAAAAACCAGTTTCTGGAAGCGCTTATCGAAAGCATGCCCAACCCTGTGTTTTTCAAGTCGCTGGA
AGGTGAATATCTGGGCTGTAATGCGGCGTTCTGCCGCATACTGGGCAAACCCAAAGAGGACATTGTGGGGCGCAGGGCAG
AAGACCTGCTGCCCGAAGAAGTGGCCTGCCGTGTGCTGGAAGGAGGTGTGCTGTCCGGTGCTCAGGAACGCGCGCATTCG
TGCACCATCACCATGCTGGGCGACGACGGCGGTCCGTTACAGCTGGTGCTGTACAAGTCGTTTTTTCAGAACAGGGCGGG
CGAAAACGCCGGTGTGGTGGGCACGTTCCACGATATCACCGAACTGAAGAAAAAAGAGGCCCAGATTTACCATCAGGCCT
ACCATGACGAGCTGACAGGGCTGGCAAACCGTGTGCGCCTGAAAGATGCCATAGCCGACCGCATACGGCTGGGCGGTGAC
GGTGGTCTGGCAGTGCTGATGCTTGATCTGGATAATTTTAAAAACGTCAACGACAGTCTGGGGCACGGTGTGGGCGACAA
GCTGCTGCTTGAGGCATCGCGCCGGCTGCGCGATGTTGTGGGCCCGCAACCGCTGCTGGCCAGAACCGGCGGCGACGAAT
TCGCGCTGCTGCTCGACGGCTGCAAGGACGTGGCAAACCGGCTTGCAGCCAAGGTGCTGGATGCCTTCACCGTTCCGTTT
GTCATTGATGAACACGAACTGTACATAACCATCAGCATCGGGCTTACCTGCTGGCCGGAAGACGGTGCCGATGCCGATTC
ACTGGTTAAAAACGCCGATGTGGCCATGTACAAGGCCAAAGAGCAGGGCCGCAGCCGCTGCCTGCATTTTGATGCCGAGA
TGACCGAACAGGTCACCAGAAGGCTGAGTATTGAAAAGAGCATCCGCAAAGGGCTGGAACGGGATGAGTTTCAGGTCTAC
TACCAGCCCAGAATCAATATTTTTAACGGCAGACTGGTAGGCATGGAGGCGCTGGTGCGCTGGGTGCCCGAACACGGTGC
CGTGGTCAGCCCGGCGGAGTTTATTCCCGTTGCCGAAGAAACGGGGCTTATTGTGGCGCTGGGCGAAAGGGTGCTGCGGC
TGGCATGTGCCCAGATGCGTATATGGGCGGACAGAGGGTGGGGTGACCTGCGTATGTCCGTCAATATTTCTGCCCGTCAG
TTTCAGGCCAATCTGACGGAACGTGTGGCCGCCGCACTGCGTGATTCCGGCATTTCTCCGGATTCGCTGGAGCTTGAAAT
CACGGAAACCACCATGATGCGTGATATCGGGCAGACAGTGCTGCTGCTTGAACAGCTGAACGGCATGGGACTGAAGATAG
CCATCGACGATTTTGGTACGGGGCATTCCTCATTGTATTATCTCAAGCGTTTCCCCATCAGCACGCTGAAGATAGATCGT
TCCTTCGTGCGCGATATCATGAAGGACGACGGCGATGCCAACATTGTATCGACCATTATCACCATGGGGCACAACCTGTC
GCTGAATGTGGTGGCCGAAGGAGTGGAAACGGACGAACAGCTGGCTTTTCTGCGCGACAAGGGATGCGTTGAAGTGCAGG
GCTTTTATTACAGCAGGCCCGTGCCGGCTGCGGAGTTTGAAGACTTCGTGCTGCGGCACCGGTCGTGA

Upstream 100 bases:

>100_bases
GGCGGTGGGGTGTGTAACTGTACGGATGCAATGATCCGGAACTTTCGCCGGCCGGTCAGCAGGCCGGCAATATCGCTTTT
TTGTTCAGCAAGGTAGGCAT

Downstream 100 bases:

>100_bases
CCGCAGCGGCTTGAAATACCTGTCAGCCCGCCTTCCGGCGGGCTTTTTCATGGCTGTCAGGGGGTTACGGGGCGGTGTCT
GCGTGTGCCTCTGTCAGACA

Product: response regulator receiver /GGDEF/PAS/PAC domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 715

Protein sequence:

>715_residues
MQHDPPRVLSIDDDRNVRENIVAYLEDSGFDVVEAENGRQGLEEFERSAPDIVLVDLRMPVMDGMQFLAELRKISKRIPV
IVVSGVGVLEEAVEALRHGAWDYVTKPISDMVVLEHAVNKALERARLLDERDRYRERLEQEVAERTGELRESNERLLEFQ
SLLQEKNQFLEALIESMPNPVFFKSLEGEYLGCNAAFCRILGKPKEDIVGRRAEDLLPEEVACRVLEGGVLSGAQERAHS
CTITMLGDDGGPLQLVLYKSFFQNRAGENAGVVGTFHDITELKKKEAQIYHQAYHDELTGLANRVRLKDAIADRIRLGGD
GGLAVLMLDLDNFKNVNDSLGHGVGDKLLLEASRRLRDVVGPQPLLARTGGDEFALLLDGCKDVANRLAAKVLDAFTVPF
VIDEHELYITISIGLTCWPEDGADADSLVKNADVAMYKAKEQGRSRCLHFDAEMTEQVTRRLSIEKSIRKGLERDEFQVY
YQPRINIFNGRLVGMEALVRWVPEHGAVVSPAEFIPVAEETGLIVALGERVLRLACAQMRIWADRGWGDLRMSVNISARQ
FQANLTERVAAALRDSGISPDSLELEITETTMMRDIGQTVLLLEQLNGMGLKIAIDDFGTGHSSLYYLKRFPISTLKIDR
SFVRDIMKDDGDANIVSTIITMGHNLSLNVVAEGVETDEQLAFLRDKGCVEVQGFYYSRPVPAAEFEDFVLRHRS

Sequences:

>Translated_715_residues
MQHDPPRVLSIDDDRNVRENIVAYLEDSGFDVVEAENGRQGLEEFERSAPDIVLVDLRMPVMDGMQFLAELRKISKRIPV
IVVSGVGVLEEAVEALRHGAWDYVTKPISDMVVLEHAVNKALERARLLDERDRYRERLEQEVAERTGELRESNERLLEFQ
SLLQEKNQFLEALIESMPNPVFFKSLEGEYLGCNAAFCRILGKPKEDIVGRRAEDLLPEEVACRVLEGGVLSGAQERAHS
CTITMLGDDGGPLQLVLYKSFFQNRAGENAGVVGTFHDITELKKKEAQIYHQAYHDELTGLANRVRLKDAIADRIRLGGD
GGLAVLMLDLDNFKNVNDSLGHGVGDKLLLEASRRLRDVVGPQPLLARTGGDEFALLLDGCKDVANRLAAKVLDAFTVPF
VIDEHELYITISIGLTCWPEDGADADSLVKNADVAMYKAKEQGRSRCLHFDAEMTEQVTRRLSIEKSIRKGLERDEFQVY
YQPRINIFNGRLVGMEALVRWVPEHGAVVSPAEFIPVAEETGLIVALGERVLRLACAQMRIWADRGWGDLRMSVNISARQ
FQANLTERVAAALRDSGISPDSLELEITETTMMRDIGQTVLLLEQLNGMGLKIAIDDFGTGHSSLYYLKRFPISTLKIDR
SFVRDIMKDDGDANIVSTIITMGHNLSLNVVAEGVETDEQLAFLRDKGCVEVQGFYYSRPVPAAEFEDFVLRHRS
>Mature_715_residues
MQHDPPRVLSIDDDRNVRENIVAYLEDSGFDVVEAENGRQGLEEFERSAPDIVLVDLRMPVMDGMQFLAELRKISKRIPV
IVVSGVGVLEEAVEALRHGAWDYVTKPISDMVVLEHAVNKALERARLLDERDRYRERLEQEVAERTGELRESNERLLEFQ
SLLQEKNQFLEALIESMPNPVFFKSLEGEYLGCNAAFCRILGKPKEDIVGRRAEDLLPEEVACRVLEGGVLSGAQERAHS
CTITMLGDDGGPLQLVLYKSFFQNRAGENAGVVGTFHDITELKKKEAQIYHQAYHDELTGLANRVRLKDAIADRIRLGGD
GGLAVLMLDLDNFKNVNDSLGHGVGDKLLLEASRRLRDVVGPQPLLARTGGDEFALLLDGCKDVANRLAAKVLDAFTVPF
VIDEHELYITISIGLTCWPEDGADADSLVKNADVAMYKAKEQGRSRCLHFDAEMTEQVTRRLSIEKSIRKGLERDEFQVY
YQPRINIFNGRLVGMEALVRWVPEHGAVVSPAEFIPVAEETGLIVALGERVLRLACAQMRIWADRGWGDLRMSVNISARQ
FQANLTERVAAALRDSGISPDSLELEITETTMMRDIGQTVLLLEQLNGMGLKIAIDDFGTGHSSLYYLKRFPISTLKIDR
SFVRDIMKDDGDANIVSTIITMGHNLSLNVVAEGVETDEQLAFLRDKGCVEVQGFYYSRPVPAAEFEDFVLRHRS

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=465, Percent_Identity=36.989247311828, Blast_Score=300, Evalue=3e-82,
Organism=Escherichia coli, GI87081921, Length=553, Percent_Identity=31.6455696202532, Blast_Score=245, Evalue=9e-66,
Organism=Escherichia coli, GI226510982, Length=397, Percent_Identity=30.9823677581864, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1790496, Length=255, Percent_Identity=32.9411764705882, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1787055, Length=294, Percent_Identity=30.952380952381, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI87081845, Length=248, Percent_Identity=35.4838709677419, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=32.8, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1786507, Length=242, Percent_Identity=33.0578512396694, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI87081743, Length=262, Percent_Identity=33.206106870229, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1788502, Length=258, Percent_Identity=32.5581395348837, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87082096, Length=250, Percent_Identity=32.4, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1788381, Length=422, Percent_Identity=27.0142180094787, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788956, Length=166, Percent_Identity=37.3493975903614, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788849, Length=244, Percent_Identity=31.1475409836066, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=44.4444444444444, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1788905, Length=134, Percent_Identity=39.5522388059701, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87081881, Length=175, Percent_Identity=36.5714285714286, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790437, Length=129, Percent_Identity=37.984496124031, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787802, Length=165, Percent_Identity=33.9393939393939, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=31.6770186335404, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=27.5280898876405, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=35.6435643564356, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081977, Length=170, Percent_Identity=28.8235294117647, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87082007, Length=228, Percent_Identity=27.6315789473684, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1786599, Length=105, Percent_Identity=35.2380952380952, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI145693134, Length=171, Percent_Identity=30.9941520467836, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1787816, Length=235, Percent_Identity=25.9574468085106, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1789402, Length=103, Percent_Identity=39.8058252427184, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786911, Length=101, Percent_Identity=37.6237623762376, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI48994928, Length=201, Percent_Identity=26.3681592039801, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787375, Length=101, Percent_Identity=32.6732673267327, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 80027; Mature: 80027

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHDPPRVLSIDDDRNVRENIVAYLEDSGFDVVEAENGRQGLEEFERSAPDIVLVDLRMP
CCCCCCCEEEECCCCCHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHCCCCEEEEEECCC
VMDGMQFLAELRKISKRIPVIVVSGVGVLEEAVEALRHGAWDYVTKPISDMVVLEHAVNK
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHH
ALERARLLDERDRYRERLEQEVAERTGELRESNERLLEFQSLLQEKNQFLEALIESMPNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VFFKSLEGEYLGCNAAFCRILGKPKEDIVGRRAEDLLPEEVACRVLEGGVLSGAQERAHS
EEEECCCCCEECCHHHHHHHHCCCHHHHHCCCHHHCCCHHHHHHHHCCCCCCCHHHCCCE
CTITMLGDDGGPLQLVLYKSFFQNRAGENAGVVGTFHDITELKKKEAQIYHQAYHDELTG
EEEEEEECCCCCEEEHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHH
LANRVRLKDAIADRIRLGGDGGLAVLMLDLDNFKNVNDSLGHGVGDKLLLEASRRLRDVV
HHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHC
GPQPLLARTGGDEFALLLDGCKDVANRLAAKVLDAFTVPFVIDEHELYITISIGLTCWPE
CCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEEEEEEEECCC
DGADADSLVKNADVAMYKAKEQGRSRCLHFDAEMTEQVTRRLSIEKSIRKGLERDEFQVY
CCCCHHHHHHCCCHHHHCCHHHHHHHEEEECHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
YQPRINIFNGRLVGMEALVRWVPEHGAVVSPAEFIPVAEETGLIVALGERVLRLACAQMR
EECCEEEECCEEHHHHHHHHHCCCCCCEECCHHHCCCCCCCCEEEHHHHHHHHHHHHHHH
IWADRGWGDLRMSVNISARQFQANLTERVAAALRDSGISPDSLELEITETTMMRDIGQTV
HHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHH
LLLEQLNGMGLKIAIDDFGTGHSSLYYLKRFPISTLKIDRSFVRDIMKDDGDANIVSTII
HHHHHHCCCEEEEEEECCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
TMGHNLSLNVVAEGVETDEQLAFLRDKGCVEVQGFYYSRPVPAAEFEDFVLRHRS
HHCCCCEEEEEECCCCCHHHHHHHHCCCCEEEECEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MQHDPPRVLSIDDDRNVRENIVAYLEDSGFDVVEAENGRQGLEEFERSAPDIVLVDLRMP
CCCCCCCEEEECCCCCHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHCCCCEEEEEECCC
VMDGMQFLAELRKISKRIPVIVVSGVGVLEEAVEALRHGAWDYVTKPISDMVVLEHAVNK
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHH
ALERARLLDERDRYRERLEQEVAERTGELRESNERLLEFQSLLQEKNQFLEALIESMPNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VFFKSLEGEYLGCNAAFCRILGKPKEDIVGRRAEDLLPEEVACRVLEGGVLSGAQERAHS
EEEECCCCCEECCHHHHHHHHCCCHHHHHCCCHHHCCCHHHHHHHHCCCCCCCHHHCCCE
CTITMLGDDGGPLQLVLYKSFFQNRAGENAGVVGTFHDITELKKKEAQIYHQAYHDELTG
EEEEEEECCCCCEEEHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHH
LANRVRLKDAIADRIRLGGDGGLAVLMLDLDNFKNVNDSLGHGVGDKLLLEASRRLRDVV
HHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHC
GPQPLLARTGGDEFALLLDGCKDVANRLAAKVLDAFTVPFVIDEHELYITISIGLTCWPE
CCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEEEEEEEECCC
DGADADSLVKNADVAMYKAKEQGRSRCLHFDAEMTEQVTRRLSIEKSIRKGLERDEFQVY
CCCCHHHHHHCCCHHHHCCHHHHHHHEEEECHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
YQPRINIFNGRLVGMEALVRWVPEHGAVVSPAEFIPVAEETGLIVALGERVLRLACAQMR
EECCEEEECCEEHHHHHHHHHCCCCCCEECCHHHCCCCCCCCEEEHHHHHHHHHHHHHHH
IWADRGWGDLRMSVNISARQFQANLTERVAAALRDSGISPDSLELEITETTMMRDIGQTV
HHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHH
LLLEQLNGMGLKIAIDDFGTGHSSLYYLKRFPISTLKIDRSFVRDIMKDDGDANIVSTII
HHHHHHCCCEEEEEEECCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
TMGHNLSLNVVAEGVETDEQLAFLRDKGCVEVQGFYYSRPVPAAEFEDFVLRHRS
HHCCCCEEEEEECCCCCHHHHHHHHCCCCEEEECEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]