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The map label for this gene is argS

Identifier: 78222646

GI number: 78222646

Start: 1603259

End: 1604968

Strand: Direct

Name: argS

Synonym: Gmet_1434

Alternate gene names: 78222646

Gene position: 1603259-1604968 (Clockwise)

Preceding gene: 78222645

Following gene: 78222647

Centisome position: 40.11

GC content: 56.78

Gene sequence:

>1710_bases
ATGAGTCAACTGGAGGGAACAATGAAGGATAGGGTTCGTTCTCTGGTCGCCGAGGGAATCGAGCGGTGTTTTGCCGACGG
CTCTCTTGCCTCGAACCAGATGCCGGCCATAGTCATAGAGAAGCCGGCCCATGCCGAGCACGGCGACTTTGCCTGTACCG
TCGCCATGTCCATGGCGAAGGCCGAGCGCAAGGCGCCGCGGGTGATTGCAGAGACAATCGTCAAACATATTGAAAATGGT
GAAAGTGGTATCATCGGGGGAATCGATATAGCCGGCCCCGGTTTTATCAACTTCAGAATCAAGAACGAGGCATGGAGCAG
AACGCTTGCGGTCGTGGAGGCGGCAGGGGCGAGCTTCGGGCGCAGCTGCGCGGGTGAAGAGCGTAAGGTGCAGGTGGAGT
TTGTGAGTGCAAACCCCACGGGACCACTCCATATCGGCCACGGACGGGGTGCCGCCATCGGTGACACCATCTGTCGCCTT
CTGTCAGCTTCCGGATTCGATGTGACCCGTGAGTTCTATTACAACGATGCCGGTGCCCAAATCGCCAATCTTGCGCTTTC
CGTTCAGTCACGCTGTCTCGGTATTGAGCCGGGAGACCCCCGGTGGCCGGCCGATGGCTATCAGGGCGACTATATCAAGG
ACGTGGCCCGCTCCTATCTCAATCGCGAAACCGTAGATGCCGGTGACCAGCACGTCACTGCCGCCGGCGACCCGAATGAC
CTTGACGCGATCCGTCGCTTTGCCGTGGCCTATCTGCGGCGCGAACAGGATCAGGACCTCCTGGCCTTCGACGTGCATTT
CGATGTCTACTCGCTTGAATCGAGCCTTTATACCGAAGGTCGTGTTGAAGAGGTAGTCAGGCGTCTGATCGAGAACGGCC
ATACCTTCGAGCAGGACGGCGCCCTCTGGTTGCGGACCACGGACTTTGGAGACGACAAGGACCGGGTCATGCGCAAGTCG
GACGGCAGTTACACCTACTTTGTCCCCGATGTTGCCTACCATCTGGCCAAGTGGGAACGTGGCTTCACCCGCGTCATTAA
CGAGCAGGGAGCGGACCACCACAGCACCATAACCCGCGTGCGTGCCGGTCTTCAGGCCCTCAATGCAGGAATCCCTCAAG
AGTGGCCCGAGTACGTTCTACACCAGATGGTTACGGTCATGCGCGGTGGTGAAGAGGTGAAAATATCCAAGCGCGCCGGT
AGCTATGTTACGTTACGAGATCTGATCGACGAAGTGGGCCGTGATGCCACGAGATTCTTCTTCCTCATGAGGAAACCTGA
TTCTCAACTGGTTTTCGATATCGATCTGGCCAAACAGCAATCACTCGAAAACCCGGTTTACTACGTCCAGTACGCCCATG
CACGGATCAGCAGCATCTTCGAGGCCGCCTGTGACCGTGGAATCAGCGTTCCGTCCTTCCCTGATGCCCATGTGGATCTT
CTCGAGACACCGGAAGAAATTGAACTCATCAAGCTCATCGGCTCTTTCCCCGAAGTTATCGAAGGAAGCGCCTTGTCCTT
CGAGCCACACCGGATCACCTACTACCTTCAGGAACTGGCAGGGGCTTTCCATTCTTTTTACAATAAAAATCGCGTCATAG
GCGAAGGGAAGGAGTTGAGTTCGGCACGGCTCTTCCTCCTCAAGGGCGTTGCTCAAGTACTGAAGAACGGGCTTGCACTC
CTGGGTGTCTCGGCACCGGAAAAGATGTAG

Upstream 100 bases:

>100_bases
GTGCGAAGAAATTCTGCGTCACCGATGGCGGCGCGCGCTGTCCCGATTTCAGCCGTGACGTTTCCATTAAGGTTCCGGAC
GAAGAATCGGATGAAATACA

Downstream 100 bases:

>100_bases
CTGGAAGGGTTTATGGTCCTTGATTATCGTGAACGGAAACCGGTCAACAAAAACCGGCCAAAATCGAAACCCGTCGGCCT
CTTTGTCATAGCATTCGGCC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSQLEGTMKDRVRSLVAEGIERCFADGSLASNQMPAIVIEKPAHAEHGDFACTVAMSMAKAERKAPRVIAETIVKHIENG
ESGIIGGIDIAGPGFINFRIKNEAWSRTLAVVEAAGASFGRSCAGEERKVQVEFVSANPTGPLHIGHGRGAAIGDTICRL
LSASGFDVTREFYYNDAGAQIANLALSVQSRCLGIEPGDPRWPADGYQGDYIKDVARSYLNRETVDAGDQHVTAAGDPND
LDAIRRFAVAYLRREQDQDLLAFDVHFDVYSLESSLYTEGRVEEVVRRLIENGHTFEQDGALWLRTTDFGDDKDRVMRKS
DGSYTYFVPDVAYHLAKWERGFTRVINEQGADHHSTITRVRAGLQALNAGIPQEWPEYVLHQMVTVMRGGEEVKISKRAG
SYVTLRDLIDEVGRDATRFFFLMRKPDSQLVFDIDLAKQQSLENPVYYVQYAHARISSIFEAACDRGISVPSFPDAHVDL
LETPEEIELIKLIGSFPEVIEGSALSFEPHRITYYLQELAGAFHSFYNKNRVIGEGKELSSARLFLLKGVAQVLKNGLAL
LGVSAPEKM

Sequences:

>Translated_569_residues
MSQLEGTMKDRVRSLVAEGIERCFADGSLASNQMPAIVIEKPAHAEHGDFACTVAMSMAKAERKAPRVIAETIVKHIENG
ESGIIGGIDIAGPGFINFRIKNEAWSRTLAVVEAAGASFGRSCAGEERKVQVEFVSANPTGPLHIGHGRGAAIGDTICRL
LSASGFDVTREFYYNDAGAQIANLALSVQSRCLGIEPGDPRWPADGYQGDYIKDVARSYLNRETVDAGDQHVTAAGDPND
LDAIRRFAVAYLRREQDQDLLAFDVHFDVYSLESSLYTEGRVEEVVRRLIENGHTFEQDGALWLRTTDFGDDKDRVMRKS
DGSYTYFVPDVAYHLAKWERGFTRVINEQGADHHSTITRVRAGLQALNAGIPQEWPEYVLHQMVTVMRGGEEVKISKRAG
SYVTLRDLIDEVGRDATRFFFLMRKPDSQLVFDIDLAKQQSLENPVYYVQYAHARISSIFEAACDRGISVPSFPDAHVDL
LETPEEIELIKLIGSFPEVIEGSALSFEPHRITYYLQELAGAFHSFYNKNRVIGEGKELSSARLFLLKGVAQVLKNGLAL
LGVSAPEKM
>Mature_568_residues
SQLEGTMKDRVRSLVAEGIERCFADGSLASNQMPAIVIEKPAHAEHGDFACTVAMSMAKAERKAPRVIAETIVKHIENGE
SGIIGGIDIAGPGFINFRIKNEAWSRTLAVVEAAGASFGRSCAGEERKVQVEFVSANPTGPLHIGHGRGAAIGDTICRLL
SASGFDVTREFYYNDAGAQIANLALSVQSRCLGIEPGDPRWPADGYQGDYIKDVARSYLNRETVDAGDQHVTAAGDPNDL
DAIRRFAVAYLRREQDQDLLAFDVHFDVYSLESSLYTEGRVEEVVRRLIENGHTFEQDGALWLRTTDFGDDKDRVMRKSD
GSYTYFVPDVAYHLAKWERGFTRVINEQGADHHSTITRVRAGLQALNAGIPQEWPEYVLHQMVTVMRGGEEVKISKRAGS
YVTLRDLIDEVGRDATRFFFLMRKPDSQLVFDIDLAKQQSLENPVYYVQYAHARISSIFEAACDRGISVPSFPDAHVDLL
ETPEEIELIKLIGSFPEVIEGSALSFEPHRITYYLQELAGAFHSFYNKNRVIGEGKELSSARLFLLKGVAQVLKNGLALL
GVSAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=589, Percent_Identity=26.3157894736842, Blast_Score=136, Evalue=5e-32,
Organism=Escherichia coli, GI1788184, Length=602, Percent_Identity=26.0797342192691, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71985061, Length=612, Percent_Identity=24.1830065359477, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71985068, Length=577, Percent_Identity=24.4367417677643, Blast_Score=111, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320548, Length=509, Percent_Identity=25.3438113948919, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6321883, Length=531, Percent_Identity=24.6704331450094, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI18859963, Length=576, Percent_Identity=23.9583333333333, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 63000; Mature: 62869

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLEGTMKDRVRSLVAEGIERCFADGSLASNQMPAIVIEKPAHAEHGDFACTVAMSMAK
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
AERKAPRVIAETIVKHIENGESGIIGGIDIAGPGFINFRIKNEAWSRTLAVVEAAGASFG
HHHHCHHHHHHHHHHHHCCCCCCEEECEEECCCCEEEEEECCHHHHHHHHHHHHHCCHHC
RSCAGEERKVQVEFVSANPTGPLHIGHGRGAAIGDTICRLLSASGFDVTREFYYNDAGAQ
CCCCCCCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCHH
IANLALSVQSRCLGIEPGDPRWPADGYQGDYIKDVARSYLNRETVDAGDQHVTAAGDPND
HHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCHH
LDAIRRFAVAYLRREQDQDLLAFDVHFDVYSLESSLYTEGRVEEVVRRLIENGHTFEQDG
HHHHHHHHHHHHHHCCCCCEEEEEEEEEHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
ALWLRTTDFGDDKDRVMRKSDGSYTYFVPDVAYHLAKWERGFTRVINEQGADHHSTITRV
EEEEEECCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RAGLQALNAGIPQEWPEYVLHQMVTVMRGGEEVKISKRAGSYVTLRDLIDEVGRDATRFF
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCCCCEEEE
FLMRKPDSQLVFDIDLAKQQSLENPVYYVQYAHARISSIFEAACDRGISVPSFPDAHVDL
EEEECCCCCEEEEEEHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LETPEEIELIKLIGSFPEVIEGSALSFEPHRITYYLQELAGAFHSFYNKNRVIGEGKELS
HCCCHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
SARLFLLKGVAQVLKNGLALLGVSAPEKM
HHHHHHHHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure 
SQLEGTMKDRVRSLVAEGIERCFADGSLASNQMPAIVIEKPAHAEHGDFACTVAMSMAK
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
AERKAPRVIAETIVKHIENGESGIIGGIDIAGPGFINFRIKNEAWSRTLAVVEAAGASFG
HHHHCHHHHHHHHHHHHCCCCCCEEECEEECCCCEEEEEECCHHHHHHHHHHHHHCCHHC
RSCAGEERKVQVEFVSANPTGPLHIGHGRGAAIGDTICRLLSASGFDVTREFYYNDAGAQ
CCCCCCCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCHH
IANLALSVQSRCLGIEPGDPRWPADGYQGDYIKDVARSYLNRETVDAGDQHVTAAGDPND
HHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCHH
LDAIRRFAVAYLRREQDQDLLAFDVHFDVYSLESSLYTEGRVEEVVRRLIENGHTFEQDG
HHHHHHHHHHHHHHCCCCCEEEEEEEEEHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
ALWLRTTDFGDDKDRVMRKSDGSYTYFVPDVAYHLAKWERGFTRVINEQGADHHSTITRV
EEEEEECCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
RAGLQALNAGIPQEWPEYVLHQMVTVMRGGEEVKISKRAGSYVTLRDLIDEVGRDATRFF
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCCCCEEEE
FLMRKPDSQLVFDIDLAKQQSLENPVYYVQYAHARISSIFEAACDRGISVPSFPDAHVDL
EEEECCCCCEEEEEEHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LETPEEIELIKLIGSFPEVIEGSALSFEPHRITYYLQELAGAFHSFYNKNRVIGEGKELS
HCCCHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
SARLFLLKGVAQVLKNGLALLGVSAPEKM
HHHHHHHHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA