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The map label for this gene is ccdA [H]

Identifier: 78222596

GI number: 78222596

Start: 1548685

End: 1549434

Strand: Direct

Name: ccdA [H]

Synonym: Gmet_1384

Alternate gene names: 78222596

Gene position: 1548685-1549434 (Clockwise)

Preceding gene: 78222595

Following gene: 78222597

Centisome position: 38.74

GC content: 58.27

Gene sequence:

>750_bases
ATGGACTTTGGTTCCGATATCACCGTCTGGATCGCATTCTCCGCAGGATTCCTTTCCTTTTTCTCACCCTGCGTTCTGCC
GCTTATCCCTTCCTATATGACCTATATCACCGGGCTCTCCTTCGGCCAGTTGCAGGAGGCACATCCGGGCGCGAAGGTGC
GTCTGGTCGTTCTGGCCCACTCCGTGGTCTTCGTCCTCGGATTCTCCGTGGTCTTCGTCGCGATGGGAGCCCTTGCCGGA
GCAGCCTCCTCCACCTTCCAGACCGTCATGAAGGACGGCCTGGTCTGGCTGCAGCGTGCTGGCGGCTTGCTCATCTTCAT
GTTCGGCGTCCACATGTCAGGGCTGTTTCACTTCGGCCTCCTGCTCGGGGACAAACGGGTCCAGATCCAGAATAAGCCGG
GCGGACTGGCAGGGACGTTCCTCGTGGGGATCGCCTTTGCCGCCGGTTGGACCCCCTGCATCGGTCCCATACTCGGGGCG
ATCCTTGCCATGGCGGCCGGCACGTCTGGATCAACCGCAACCAGCATGCTGCTGCTCGGAAGCTATGCTGCGGGGTTGGG
AATACCGTTCGTCATCTCGGGTTTGCTGTTCCACGGTTTTCTCGATATTTTCAAGCGCTTCAAGTCGCACATCCGGAAGA
TGGAGTTCTTTACAGGGTTATTGCTGATGTCAGTAGGCATCCTTCTCTTCTTCGGTCTCTTCAACAACTTGACCACCTTG
CTTTACCAGTGGCTCCCGATGGGGGCCTGA

Upstream 100 bases:

>100_bases
GACCGCAAGGGGATTATCCGGCAGCGGGTGACCGGCGGCATCGAGTGGGACGCCCCCAAGGTCGTCAGCTACCTGAAATC
ACTGTAGCGGAGATACCATC

Downstream 100 bases:

>100_bases
ATCAACCTGCAGTGGAGTGTATCAATGCCTTTCTGGCCAGGTTGAAGCAACATCCAACAGCAAACGACAGGATCGCCATC
CTCTGCACGCACCCCAGATC

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MDFGSDITVWIAFSAGFLSFFSPCVLPLIPSYMTYITGLSFGQLQEAHPGAKVRLVVLAHSVVFVLGFSVVFVAMGALAG
AASSTFQTVMKDGLVWLQRAGGLLIFMFGVHMSGLFHFGLLLGDKRVQIQNKPGGLAGTFLVGIAFAAGWTPCIGPILGA
ILAMAAGTSGSTATSMLLLGSYAAGLGIPFVISGLLFHGFLDIFKRFKSHIRKMEFFTGLLLMSVGILLFFGLFNNLTTL
LYQWLPMGA

Sequences:

>Translated_249_residues
MDFGSDITVWIAFSAGFLSFFSPCVLPLIPSYMTYITGLSFGQLQEAHPGAKVRLVVLAHSVVFVLGFSVVFVAMGALAG
AASSTFQTVMKDGLVWLQRAGGLLIFMFGVHMSGLFHFGLLLGDKRVQIQNKPGGLAGTFLVGIAFAAGWTPCIGPILGA
ILAMAAGTSGSTATSMLLLGSYAAGLGIPFVISGLLFHGFLDIFKRFKSHIRKMEFFTGLLLMSVGILLFFGLFNNLTTL
LYQWLPMGA
>Mature_249_residues
MDFGSDITVWIAFSAGFLSFFSPCVLPLIPSYMTYITGLSFGQLQEAHPGAKVRLVVLAHSVVFVLGFSVVFVAMGALAG
AASSTFQTVMKDGLVWLQRAGGLLIFMFGVHMSGLFHFGLLLGDKRVQIQNKPGGLAGTFLVGIAFAAGWTPCIGPILGA
ILAMAAGTSGSTATSMLLLGSYAAGLGIPFVISGLLFHGFLDIFKRFKSHIRKMEFFTGLLLMSVGILLFFGLFNNLTTL
LYQWLPMGA

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26521; Mature: 26521

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFGSDITVWIAFSAGFLSFFSPCVLPLIPSYMTYITGLSFGQLQEAHPGAKVRLVVLAH
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEHHHHHH
SVVFVLGFSVVFVAMGALAGAASSTFQTVMKDGLVWLQRAGGLLIFMFGVHMSGLFHFGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLGDKRVQIQNKPGGLAGTFLVGIAFAAGWTPCIGPILGAILAMAAGTSGSTATSMLLLG
HHCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SYAAGLGIPFVISGLLFHGFLDIFKRFKSHIRKMEFFTGLLLMSVGILLFFGLFNNLTTL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYQWLPMGA
HHHHHCCCC
>Mature Secondary Structure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HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]