Click here to switch to the map view.

The map label for this gene is atoS [H]

Identifier: 78222591

GI number: 78222591

Start: 1542427

End: 1544166

Strand: Reverse

Name: atoS [H]

Synonym: Gmet_1379

Alternate gene names: 78222591

Gene position: 1544166-1542427 (Counterclockwise)

Preceding gene: 78222641

Following gene: 78222590

Centisome position: 38.63

GC content: 52.13

Gene sequence:

>1740_bases
ATGTTGAAATTTATCGAAGCCAATAAAAAACGCATCGTCATCGTTACCTATATCCTGCTCTTCTGCATGTTCTGCTTCTT
TTCCCTGATGGATCTGTACAAGAGGACTTCCGACTACGCCTATTTCGCCAACAAAATCAACTCATTCATCAAGCATGCCC
ACGACAGCGAATCGGAGTATCTCTGTTCGCGCCTGGTCAACTACGTAAGCGACATCGCAAAACAAAAGCACTTCGCCGAA
CTGCTGAAAGCAGGCGACGCAGAAGCCCTGGAGAAGGTGGCCAATCACGCTTTCTACGACTTCGGGAAACGCTATGTGCC
GGTGATCTCGGTCCTCATCTATGACGGCGATGGAAAACTCAGATATCATATGACACCGCCGTCGATCACCCATGACCCCG
AGGAATTAAGACCGAACGTTAGCAAAGAGGTCTTTGCCACGAAAAACTACACCTACGGGTATGAGACCAACATCGTTCCC
CTCTACTTCTGCATTGTTCTTCCTGTACGGGACGCTCGTTCAAATGTGGAAGGAACGATCGAGATAGGTGTGGACCTGTC
ATTTTTTCACTACAATCTGAAATGGTTTTTACACGACGTAAAGACAGCCATCTTCTCCAATGGGAAACTCCTTGAATTTG
ACACCGGGGACAAGACGGATTCCGAGGAATATGTCTATGACTATTATAAAAAGCTGAAATCCAACGACGCCGCGTTCTTC
AACCAGTTCAAAGACAGGATTGATTTCAGATGGGCGAAAAACGACATCAAAATCGGAGACAAGTATTACCTGGTGAGTAC
GTCCCAGGTACTTAGAGACAACCTAGGTCGCGAAGTCGGTAAATATCTTGTCGCCTACGACATGACTGAGCTGCGGAACC
GGCACTGGGGATATTTCTACGCATGGCTGCTGTTCTTCGCCCTCACCGCCTGCGTCATGCTCTGTATCAACATGGTCGGG
TTCAGAAAGTATGAGCACATCATCACGGAACAGGACAAGATGCTGGCCCAGCGGTCAAAGCAGTGCGCACTCGGGGAAAT
GCTGGGACACATCGGACACCAATGGCGACAACCTCTCTACAACCTTTCTCTGATCGTTCAGAACATCGGGCTGCAGAACC
AGTACGGCAAACTGGACGACGCCCTGCTCAGCAAGCAGATTACCCAGGCGAACCAGAACATCGAATACATGTCTAACATC
ATAGATGACTGGCGTTCACTGCTCATGTCGGGCAGCAGCCGGACCGTGATCGAGCTGCAGAGTTCCGTCGAGCGCGCCAT
AGCGATGGTTGCGCCGGTCATGGAGCAGAGCCGGGTCACCATCGAGAACCGGATCACGACGCCGGTGCACACCATGGGTT
TCGTGAACGACCTGGTGCAGCTGACCATAAACGTGCTGTTGAATGCGCGCGATCAGCTTTCCCTGGTGCAAAGTGACCGC
TTCATCCTGCTCTCCTGCAACGAGGAGTCGGGAGGGGTGGTGACGGTCACCTTCCAGGACAACGGTGGCGGGATCCCCGA
CCATCTGCTCAAACGCATTTTCGAACCGTATGTCACCACCAAGGACAAGGCCGACGGCACAGGACTGGGACTGTATCTGT
GCCACCAGATCGTCGAGAATCTGGACCAGGGGAAGGTCTGGGCGGAGAACAGGTCCTTTGAACTGCACGGGGAAACGCAC
TATGGCGCCCGCATCTGCCTGCAGTTCGCCAGAACAACCGAGGGAGGTAAACAGATATGA

Upstream 100 bases:

>100_bases
TAGTTTTACATGCTGGTGCTCACCGCCGACTGGAGTACCCTTGCGCCGCCAGGAGCACCGGCTCGACAATCACGAGTACC
CCCCAAGAGGGACGCGCCCC

Downstream 100 bases:

>100_bases
ATGTCACCGCCTTGCAACAGATGACGGTGCTCTTTGTGGACGACGAGGAGATTGCACGGGAGCAGATGAAGATGGTCCTG
AGCAGTTTCTGCAAAAACAC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 579

Protein sequence:

>579_residues
MLKFIEANKKRIVIVTYILLFCMFCFFSLMDLYKRTSDYAYFANKINSFIKHAHDSESEYLCSRLVNYVSDIAKQKHFAE
LLKAGDAEALEKVANHAFYDFGKRYVPVISVLIYDGDGKLRYHMTPPSITHDPEELRPNVSKEVFATKNYTYGYETNIVP
LYFCIVLPVRDARSNVEGTIEIGVDLSFFHYNLKWFLHDVKTAIFSNGKLLEFDTGDKTDSEEYVYDYYKKLKSNDAAFF
NQFKDRIDFRWAKNDIKIGDKYYLVSTSQVLRDNLGREVGKYLVAYDMTELRNRHWGYFYAWLLFFALTACVMLCINMVG
FRKYEHIITEQDKMLAQRSKQCALGEMLGHIGHQWRQPLYNLSLIVQNIGLQNQYGKLDDALLSKQITQANQNIEYMSNI
IDDWRSLLMSGSSRTVIELQSSVERAIAMVAPVMEQSRVTIENRITTPVHTMGFVNDLVQLTINVLLNARDQLSLVQSDR
FILLSCNEESGGVVTVTFQDNGGGIPDHLLKRIFEPYVTTKDKADGTGLGLYLCHQIVENLDQGKVWAENRSFELHGETH
YGARICLQFARTTEGGKQI

Sequences:

>Translated_579_residues
MLKFIEANKKRIVIVTYILLFCMFCFFSLMDLYKRTSDYAYFANKINSFIKHAHDSESEYLCSRLVNYVSDIAKQKHFAE
LLKAGDAEALEKVANHAFYDFGKRYVPVISVLIYDGDGKLRYHMTPPSITHDPEELRPNVSKEVFATKNYTYGYETNIVP
LYFCIVLPVRDARSNVEGTIEIGVDLSFFHYNLKWFLHDVKTAIFSNGKLLEFDTGDKTDSEEYVYDYYKKLKSNDAAFF
NQFKDRIDFRWAKNDIKIGDKYYLVSTSQVLRDNLGREVGKYLVAYDMTELRNRHWGYFYAWLLFFALTACVMLCINMVG
FRKYEHIITEQDKMLAQRSKQCALGEMLGHIGHQWRQPLYNLSLIVQNIGLQNQYGKLDDALLSKQITQANQNIEYMSNI
IDDWRSLLMSGSSRTVIELQSSVERAIAMVAPVMEQSRVTIENRITTPVHTMGFVNDLVQLTINVLLNARDQLSLVQSDR
FILLSCNEESGGVVTVTFQDNGGGIPDHLLKRIFEPYVTTKDKADGTGLGLYLCHQIVENLDQGKVWAENRSFELHGETH
YGARICLQFARTTEGGKQI
>Mature_579_residues
MLKFIEANKKRIVIVTYILLFCMFCFFSLMDLYKRTSDYAYFANKINSFIKHAHDSESEYLCSRLVNYVSDIAKQKHFAE
LLKAGDAEALEKVANHAFYDFGKRYVPVISVLIYDGDGKLRYHMTPPSITHDPEELRPNVSKEVFATKNYTYGYETNIVP
LYFCIVLPVRDARSNVEGTIEIGVDLSFFHYNLKWFLHDVKTAIFSNGKLLEFDTGDKTDSEEYVYDYYKKLKSNDAAFF
NQFKDRIDFRWAKNDIKIGDKYYLVSTSQVLRDNLGREVGKYLVAYDMTELRNRHWGYFYAWLLFFALTACVMLCINMVG
FRKYEHIITEQDKMLAQRSKQCALGEMLGHIGHQWRQPLYNLSLIVQNIGLQNQYGKLDDALLSKQITQANQNIEYMSNI
IDDWRSLLMSGSSRTVIELQSSVERAIAMVAPVMEQSRVTIENRITTPVHTMGFVNDLVQLTINVLLNARDQLSLVQSDR
FILLSCNEESGGVVTVTFQDNGGGIPDHLLKRIFEPYVTTKDKADGTGLGLYLCHQIVENLDQGKVWAENRSFELHGETH
YGARICLQFARTTEGGKQI

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=293, Percent_Identity=25.5972696245734, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66722; Mature: 66722

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFIEANKKRIVIVTYILLFCMFCFFSLMDLYKRTSDYAYFANKINSFIKHAHDSESEY
CCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
LCSRLVNYVSDIAKQKHFAELLKAGDAEALEKVANHAFYDFGKRYVPVISVLIYDGDGKL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHEEEEEEEECCCCEE
RYHMTPPSITHDPEELRPNVSKEVFATKNYTYGYETNIVPLYFCIVLPVRDARSNVEGTI
EEEECCCCCCCCHHHHCCCCCHHHEEECCCCCCCCCCCHHHHHHHHHCCHHHCCCCCEEE
EIGVDLSFFHYNLKWFLHDVKTAIFSNGKLLEFDTGDKTDSEEYVYDYYKKLKSNDAAFF
EEEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCHHHH
NQFKDRIDFRWAKNDIKIGDKYYLVSTSQVLRDNLGREVGKYLVAYDMTELRNRHWGYFY
HHHHHHHCCEECCCCEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AWLLFFALTACVMLCINMVGFRKYEHIITEQDKMLAQRSKQCALGEMLGHIGHQWRQPLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLSLIVQNIGLQNQYGKLDDALLSKQITQANQNIEYMSNIIDDWRSLLMSGSSRTVIELQ
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEHHHH
SSVERAIAMVAPVMEQSRVTIENRITTPVHTMGFVNDLVQLTINVLLNARDQLSLVQSDR
HHHHHHHHHHHHHHHHCCEEHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
FILLSCNEESGGVVTVTFQDNGGGIPDHLLKRIFEPYVTTKDKADGTGLGLYLCHQIVEN
EEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
LDQGKVWAENRSFELHGETHYGARICLQFARTTEGGKQI
CCCCCEEECCCCEEECCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLKFIEANKKRIVIVTYILLFCMFCFFSLMDLYKRTSDYAYFANKINSFIKHAHDSESEY
CCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
LCSRLVNYVSDIAKQKHFAELLKAGDAEALEKVANHAFYDFGKRYVPVISVLIYDGDGKL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHEEEEEEEECCCCEE
RYHMTPPSITHDPEELRPNVSKEVFATKNYTYGYETNIVPLYFCIVLPVRDARSNVEGTI
EEEECCCCCCCCHHHHCCCCCHHHEEECCCCCCCCCCCHHHHHHHHHCCHHHCCCCCEEE
EIGVDLSFFHYNLKWFLHDVKTAIFSNGKLLEFDTGDKTDSEEYVYDYYKKLKSNDAAFF
EEEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCHHHH
NQFKDRIDFRWAKNDIKIGDKYYLVSTSQVLRDNLGREVGKYLVAYDMTELRNRHWGYFY
HHHHHHHCCEECCCCEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AWLLFFALTACVMLCINMVGFRKYEHIITEQDKMLAQRSKQCALGEMLGHIGHQWRQPLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLSLIVQNIGLQNQYGKLDDALLSKQITQANQNIEYMSNIIDDWRSLLMSGSSRTVIELQ
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEHHHH
SSVERAIAMVAPVMEQSRVTIENRITTPVHTMGFVNDLVQLTINVLLNARDQLSLVQSDR
HHHHHHHHHHHHHHHHCCEEHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
FILLSCNEESGGVVTVTFQDNGGGIPDHLLKRIFEPYVTTKDKADGTGLGLYLCHQIVEN
EEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
LDQGKVWAENRSFELHGETHYGARICLQFARTTEGGKQI
CCCCCEEECCCCEEECCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]