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The map label for this gene is hprK [H]

Identifier: 78222499

GI number: 78222499

Start: 1445584

End: 1446543

Strand: Direct

Name: hprK [H]

Synonym: Gmet_1285

Alternate gene names: 78222499

Gene position: 1445584-1446543 (Clockwise)

Preceding gene: 78222498

Following gene: 78222500

Centisome position: 36.16

GC content: 56.15

Gene sequence:

>960_bases
TTGAACACCATCAGCCTCTCAATCGAAGACCTCCTCAATGACACGGAGTACGGTCTCGACCTCTCCCTCGTTGCGGGAAG
GGGAGGGGTCGGCCATCGTGTGTTCAGCTCTCGCATTCAGAAGCCGGGCCTGGCCCTCACCGGGTACACCGACCACCTCC
ATCCGGACCGGGTACAGGTGCTCGGGAATACCGAAATATCCTACTTGCGCCAGCTCCACGAGGAACTTGCTACGATTTTC
GTCGACAAGTTCTGCGAATACCCTATTTCCTGCATCATCGTCACCAAGGGGCTTGATCCGCCCCAGTTCCTCAAGGATGC
GGCCGAACGCGAAGCAATCCCCCTGCTGGTGACGCCACTTCAGTCGTCAACTTTTATCTCGCTCATTACAAAGTTTCTTG
AGGAGCGGCTTCTCCCCACGACCCATATCCATGGTGTGCTCGTGGACGTTCTCGGCGTGGGCGTTCTGCTGCTGGGGAAA
AGCGGCATCGGCAAGAGTGAGTGCGCTCTTGACTTGGTCATACGTGGTCACCGCCTCGTGGCAGACGACGTGGTGTTCGT
GAAGAAGAAGATGCCGGCAGCCCTTGTTGGACAGGCTGCTGAGGCAATTCAGTATCACATCGAAATCAGGGGACTTGGCG
TCCTCAACATCAAGAACCTTTTCGGCGTCTCCTCTATCCGTGAAAAAAAGATCATTGAGATGGTGATCGAGCTGGTTGAG
TGGGACCCTCAGCAAGAATATGACCGTCTCGGCCTTGACGACGAAGTATATACCATTCTCGATCTGGAGCTCCCCTACAT
CAAGATTCCCGTCAGACCCGGACGCAACCTTACCTCCATCATCGAGGTGGCCGCCCGCAACCATCTCCTCAAGGGAATGG
GTTACCACTCGGCCCGGGAGTTCCAGGAGAAGCTCCTGGCTCGGATGGAAAACCGTCCTCTTGGGGATGAGGTGGAGTAG

Upstream 100 bases:

>100_bases
GAGCCGTCGCGCAAATAAAGAAGGATGCGCCGCGCCGCTGATTTGATTCGCGTGCGCGGCGCCCTTCCCTTTGCCTTGCG
GCGTGGAGGGAGATCAGCAG

Downstream 100 bases:

>100_bases
CCGATGCGCGTTCTGGTAATCTCCGGTCTGTCCGGTTCGGGCAAGTCGACGGCGGTTCGCGTTCTGGAGGATGAGGGGTT
TTTCTGCATCGACAATCTTC

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNTISLSIEDLLNDTEYGLDLSLVAGRGGVGHRVFSSRIQKPGLALTGYTDHLHPDRVQVLGNTEISYLRQLHEELATIF
VDKFCEYPISCIIVTKGLDPPQFLKDAAEREAIPLLVTPLQSSTFISLITKFLEERLLPTTHIHGVLVDVLGVGVLLLGK
SGIGKSECALDLVIRGHRLVADDVVFVKKKMPAALVGQAAEAIQYHIEIRGLGVLNIKNLFGVSSIREKKIIEMVIELVE
WDPQQEYDRLGLDDEVYTILDLELPYIKIPVRPGRNLTSIIEVAARNHLLKGMGYHSAREFQEKLLARMENRPLGDEVE

Sequences:

>Translated_319_residues
MNTISLSIEDLLNDTEYGLDLSLVAGRGGVGHRVFSSRIQKPGLALTGYTDHLHPDRVQVLGNTEISYLRQLHEELATIF
VDKFCEYPISCIIVTKGLDPPQFLKDAAEREAIPLLVTPLQSSTFISLITKFLEERLLPTTHIHGVLVDVLGVGVLLLGK
SGIGKSECALDLVIRGHRLVADDVVFVKKKMPAALVGQAAEAIQYHIEIRGLGVLNIKNLFGVSSIREKKIIEMVIELVE
WDPQQEYDRLGLDDEVYTILDLELPYIKIPVRPGRNLTSIIEVAARNHLLKGMGYHSAREFQEKLLARMENRPLGDEVE
>Mature_319_residues
MNTISLSIEDLLNDTEYGLDLSLVAGRGGVGHRVFSSRIQKPGLALTGYTDHLHPDRVQVLGNTEISYLRQLHEELATIF
VDKFCEYPISCIIVTKGLDPPQFLKDAAEREAIPLLVTPLQSSTFISLITKFLEERLLPTTHIHGVLVDVLGVGVLLLGK
SGIGKSECALDLVIRGHRLVADDVVFVKKKMPAALVGQAAEAIQYHIEIRGLGVLNIKNLFGVSSIREKKIIEMVIELVE
WDPQQEYDRLGLDDEVYTILDLELPYIKIPVRPGRNLTSIIEVAARNHLLKGMGYHSAREFQEKLLARMENRPLGDEVE

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 35560; Mature: 35560

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTISLSIEDLLNDTEYGLDLSLVAGRGGVGHRVFSSRIQKPGLALTGYTDHLHPDRVQV
CCEEEEEHHHHCCCHHCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEE
LGNTEISYLRQLHEELATIFVDKFCEYPISCIIVTKGLDPPQFLKDAAEREAIPLLVTPL
ECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEECC
QSSTFISLITKFLEERLLPTTHIHGVLVDVLGVGVLLLGKSGIGKSECALDLVIRGHRLV
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCEEE
ADDVVFVKKKMPAALVGQAAEAIQYHIEIRGLGVLNIKNLFGVSSIREKKIIEMVIELVE
HHHHHHHHHCCCHHHHHHHHHHHEEEEEEEECEEEEHHHHHCHHHHHHHHHHHHHHHHHC
WDPQQEYDRLGLDDEVYTILDLELPYIKIPVRPGRNLTSIIEVAARNHLLKGMGYHSARE
CCCHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
FQEKLLARMENRPLGDEVE
HHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNTISLSIEDLLNDTEYGLDLSLVAGRGGVGHRVFSSRIQKPGLALTGYTDHLHPDRVQV
CCEEEEEHHHHCCCHHCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEE
LGNTEISYLRQLHEELATIFVDKFCEYPISCIIVTKGLDPPQFLKDAAEREAIPLLVTPL
ECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEECC
QSSTFISLITKFLEERLLPTTHIHGVLVDVLGVGVLLLGKSGIGKSECALDLVIRGHRLV
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCEEE
ADDVVFVKKKMPAALVGQAAEAIQYHIEIRGLGVLNIKNLFGVSSIREKKIIEMVIELVE
HHHHHHHHHCCCHHHHHHHHHHHEEEEEEEECEEEEHHHHHCHHHHHHHHHHHHHHHHHC
WDPQQEYDRLGLDDEVYTILDLELPYIKIPVRPGRNLTSIIEVAARNHLLKGMGYHSARE
CCCHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
FQEKLLARMENRPLGDEVE
HHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA