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The map label for this gene is accA

Identifier: 78222431

GI number: 78222431

Start: 1369784

End: 1370740

Strand: Direct

Name: accA

Synonym: Gmet_1216

Alternate gene names: 78222431

Gene position: 1369784-1370740 (Clockwise)

Preceding gene: 78222430

Following gene: 78222432

Centisome position: 34.27

GC content: 63.43

Gene sequence:

>957_bases
ATGGCTTCCCAATATCAACTTGAATTCGAAAAGCCGGTGTTTGAGCTGGAGCAGAAAATCCAGGAGCTGGCCGACATTGC
CGGCGACAATGTGGAACTGAAGACCGAGGTGGTCAAGCTGGAGAAGAAAGTGGACAAGATGCGGGAAGTGATCTTCGCCA
ACCTCTCCCGCTGGCAGATGGTCCAGGTGGCTCGCCACATCGACCGCCCCTTCACCCTCGACTACCTCACCCACATTTTC
ACCGATTTCGTGGAGCTCCACGGCGACCGCCTCTTCGGCGACGACCACGCCATCGTCGGCGGCATGGCCAAGCTGGACGG
CGAGCCGGTCATGGTCATCGGCCACCAGAAGGGGCGCGACACCAAGGAAAAGGTCTACCGCAACTTCGGCATGCCCAACC
CCGAGGGGTACCGCAAGGCCCTGCGCCTCATGGAGATGGCCGAGCGGTTCCGGATGCCGATCATCACCTTCGTGGATACC
CCCGGCGCATACCCTGGCATCGGAGCCGAGGAGCGGGGCCAGGCTGAGGCCATTGCCCGCAACCTGCGGGAGATGGCGGC
GCTGACCGTGCCGATCATCGTGGTCATCACCGGCGAAGGGGGCTCCGGCGGAGCCCTGGCCATTGCCGTGGGAGACCGGG
TCCTGATGCTCGAATACTCCATCTACGCCGTCATTTCCCCCGAGGGGTGCGCCGCCATCCTCTGGTCCGACGGCACCAAG
GGGGCCCAGGCCGCCGAAGCCCTGAAGCTCACTGCCCCCGACCTCAAGGAGTTGGACGTCATCGACGAGATCGTGAAGGA
GCCCCTGGGGGGTGCCCACCGGGACCACGAGACCATGGCCAAGAACCTCCACGAGGCCCTTGCCCGGCACCTGAAGGAGC
TGAAGGCACTTTCCGTGGAGCAGCTCGTTGAGGGGCGGTACCAGAAGTTTAGGAAGATGAGCCGCTTCGCAGAGTAG

Upstream 100 bases:

>100_bases
TTGAAGTGAAGAACCTCTTCGGCTATCATGCCGTGTCTTTTGAGTAACCGCCTCGCAGCGTTGACAATACATCAGAAAGA
ATCGTGCAAAGGAGACGTTA

Downstream 100 bases:

>100_bases
GCACCTCAGGCAGATCGACTGGGCAAAGGCTAGCGGTGAGGGGAGAAAATACTCAGATCCCTCGCCCCTGGCCTTTCGCC
TTTTTCAGGAGACATGCATG

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MASQYQLEFEKPVFELEQKIQELADIAGDNVELKTEVVKLEKKVDKMREVIFANLSRWQMVQVARHIDRPFTLDYLTHIF
TDFVELHGDRLFGDDHAIVGGMAKLDGEPVMVIGHQKGRDTKEKVYRNFGMPNPEGYRKALRLMEMAERFRMPIITFVDT
PGAYPGIGAEERGQAEAIARNLREMAALTVPIIVVITGEGGSGGALAIAVGDRVLMLEYSIYAVISPEGCAAILWSDGTK
GAQAAEALKLTAPDLKELDVIDEIVKEPLGGAHRDHETMAKNLHEALARHLKELKALSVEQLVEGRYQKFRKMSRFAE

Sequences:

>Translated_318_residues
MASQYQLEFEKPVFELEQKIQELADIAGDNVELKTEVVKLEKKVDKMREVIFANLSRWQMVQVARHIDRPFTLDYLTHIF
TDFVELHGDRLFGDDHAIVGGMAKLDGEPVMVIGHQKGRDTKEKVYRNFGMPNPEGYRKALRLMEMAERFRMPIITFVDT
PGAYPGIGAEERGQAEAIARNLREMAALTVPIIVVITGEGGSGGALAIAVGDRVLMLEYSIYAVISPEGCAAILWSDGTK
GAQAAEALKLTAPDLKELDVIDEIVKEPLGGAHRDHETMAKNLHEALARHLKELKALSVEQLVEGRYQKFRKMSRFAE
>Mature_317_residues
ASQYQLEFEKPVFELEQKIQELADIAGDNVELKTEVVKLEKKVDKMREVIFANLSRWQMVQVARHIDRPFTLDYLTHIFT
DFVELHGDRLFGDDHAIVGGMAKLDGEPVMVIGHQKGRDTKEKVYRNFGMPNPEGYRKALRLMEMAERFRMPIITFVDTP
GAYPGIGAEERGQAEAIARNLREMAALTVPIIVVITGEGGSGGALAIAVGDRVLMLEYSIYAVISPEGCAAILWSDGTKG
AQAAEALKLTAPDLKELDVIDEIVKEPLGGAHRDHETMAKNLHEALARHLKELKALSVEQLVEGRYQKFRKMSRFAE

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=308, Percent_Identity=60.0649350649351, Blast_Score=384, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_GEOMG (Q39WC1)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_384178.1
- ProteinModelPortal:   Q39WC1
- SMR:   Q39WC1
- STRING:   Q39WC1
- GeneID:   3738756
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_1216
- NMPDR:   fig|269799.3.peg.1783
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   Q39WC1
- ProtClustDB:   PRK05724
- BioCyc:   GMET269799:GMET_1216-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35560; Mature: 35428

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQYQLEFEKPVFELEQKIQELADIAGDNVELKTEVVKLEKKVDKMREVIFANLSRWQM
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQVARHIDRPFTLDYLTHIFTDFVELHGDRLFGDDHAIVGGMAKLDGEPVMVIGHQKGRD
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHCCCCEEEEEECCCCCC
TKEKVYRNFGMPNPEGYRKALRLMEMAERFRMPIITFVDTPGAYPGIGAEERGQAEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
NLREMAALTVPIIVVITGEGGSGGALAIAVGDRVLMLEYSIYAVISPEGCAAILWSDGTK
HHHHHHHHHEEEEEEEECCCCCCCEEEEEECCEEEEEEEEEEEEECCCCCEEEEECCCCC
GAQAAEALKLTAPDLKELDVIDEIVKEPLGGAHRDHETMAKNLHEALARHLKELKALSVE
CHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVEGRYQKFRKMSRFAE
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASQYQLEFEKPVFELEQKIQELADIAGDNVELKTEVVKLEKKVDKMREVIFANLSRWQM
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VQVARHIDRPFTLDYLTHIFTDFVELHGDRLFGDDHAIVGGMAKLDGEPVMVIGHQKGRD
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHCCCCEEEEEECCCCCC
TKEKVYRNFGMPNPEGYRKALRLMEMAERFRMPIITFVDTPGAYPGIGAEERGQAEAIAR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
NLREMAALTVPIIVVITGEGGSGGALAIAVGDRVLMLEYSIYAVISPEGCAAILWSDGTK
HHHHHHHHHEEEEEEEECCCCCCCEEEEEECCEEEEEEEEEEEEECCCCCEEEEECCCCC
GAQAAEALKLTAPDLKELDVIDEIVKEPLGGAHRDHETMAKNLHEALARHLKELKALSVE
CHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QLVEGRYQKFRKMSRFAE
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA