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The map label for this gene is yfjD [C]

Identifier: 78222369

GI number: 78222369

Start: 1278894

End: 1280237

Strand: Direct

Name: yfjD [C]

Synonym: Gmet_1153

Alternate gene names: 78222369

Gene position: 1278894-1280237 (Clockwise)

Preceding gene: 78222367

Following gene: 78222370

Centisome position: 31.99

GC content: 57.96

Gene sequence:

>1344_bases
TTGGAGTCGGTTTTAGGCGAGTTGGCCGTCATATTCCTTCTTATCCTTGGTAACGGTTTTTTTGCCGGTTCAGAGCTTGC
CATCATTTCTGCCCGCAAGAGCAGGATCGCGCAACTGGTCGCCGCCGGCGACCCGAAGGCGAAGATCGTCGAACAACTTC
AAGACGATCCGCACCGGTTTCTCGCCACCGTCCAGATCGGGGTCACGCTGGTGGGCTCCCTTGCCTCGGCCGTCGGCGGC
GCCACGGCGGTCCGTTACCTGAAACCCCTCCTGGAGGGGAGTTCCATCAAGTTTTTCCATAATGCCGCCGAACCGCTTTC
CATCGGCATCGTGGTGGTCCTGATCTCCTACTTTTCCCTCATTTTCGGCGAGTTGGTCCCCAAGACCGTCGGGCTTCAGT
ACGCGGACCGGATGGCCCTCCATGTGGCCAAGCCGATCAATTTCATGGCTCGCGTCACCGGGGTGGTGGTAAGTTTCCTC
ACCCTCTCCAATCGGGCTGTCCTCGCCGTGCTGGGGATCAAGGCAGAAGGAGATCAGGCCTTCGTCACCCCCGAGGAGGT
CCAGCATATCGTGGCGGAAGGTCACGAGGCGGGTGTATTCAGTTCCACCGAGCAGGAGTTCATCCGCAATATCTTTGATT
TTACCCACACCTGTGTCCGGGAGGTGATGGTGCCCCGTACCCGCGTTGTCGCCCTTGATCTGGGACTTTCGCGAGACGAA
CTGGTCAACACGGTGCTCGAAAACAAGTATTCCCGCTATCCCGTCTACCGGGAGAGCATCGAGAACGTAACTGGTTTTAT
CCACGGAAAGGATCTTCTCGGGGGAATAGTGACTGACCCTGCCTTCGACATCAAGTCGATCATTCGTCCGCCGTTTTATG
TCCCTGAGGGAAAGAAGGTCAATGAGCTGCTGAAGGAAATGCAACGCAAGCGGATTCACATGGCCCTCGTGGTGGACGAA
TACGGCGGCATCAGCGGCCTTGCCACGACGGAGGATCTTCTGGAGGAACTCGTGGGTGAGATCGAGGATGAGCACGACAT
CGGCGAGCCGGGGAGCATCCAGCGGCTTCCAGACGGCAGCCTCCTGGTGGACGCCCTCGTCTCCATCAGCGACCTTGCGG
AGCATCTGGAAATAAAGCTTGGGGACGATATCCCCTATGATACCCTGGCAGGGCTCATTCTCGATCGGCTTGGCCGTTTC
CCGGAAAAGGGGGAGCGCGTTGAGTGGGACCGATTTACCCTCATCTGCGAGGAGGTGAAAAAGACCGCCGTTGTCAAGGT
CCGGATCGTGGAAACGGTACCGTCGGATTCAGGTCACGAAGAAGACGGGGATGTGAAGGTCTGA

Upstream 100 bases:

>100_bases
AGCGCGGGGTGCGGTTTCACTATGCCAAAATTATGCTACTATTCAACTATTTAATTGTGCGCTGGTCCCGTGCTGTGCAC
TTGCCCTGTGGAGGTACTGT

Downstream 100 bases:

>100_bases
GGTCAAGGATGGATAGAGGACACTTCTACGCGCTGGTGGCATTTTCCTTTTGTGCGATTCTCGGTTACGTGGTCTATGCC
ATTGTGTCACCGTTTCTGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MESVLGELAVIFLLILGNGFFAGSELAIISARKSRIAQLVAAGDPKAKIVEQLQDDPHRFLATVQIGVTLVGSLASAVGG
ATAVRYLKPLLEGSSIKFFHNAAEPLSIGIVVVLISYFSLIFGELVPKTVGLQYADRMALHVAKPINFMARVTGVVVSFL
TLSNRAVLAVLGIKAEGDQAFVTPEEVQHIVAEGHEAGVFSSTEQEFIRNIFDFTHTCVREVMVPRTRVVALDLGLSRDE
LVNTVLENKYSRYPVYRESIENVTGFIHGKDLLGGIVTDPAFDIKSIIRPPFYVPEGKKVNELLKEMQRKRIHMALVVDE
YGGISGLATTEDLLEELVGEIEDEHDIGEPGSIQRLPDGSLLVDALVSISDLAEHLEIKLGDDIPYDTLAGLILDRLGRF
PEKGERVEWDRFTLICEEVKKTAVVKVRIVETVPSDSGHEEDGDVKV

Sequences:

>Translated_447_residues
MESVLGELAVIFLLILGNGFFAGSELAIISARKSRIAQLVAAGDPKAKIVEQLQDDPHRFLATVQIGVTLVGSLASAVGG
ATAVRYLKPLLEGSSIKFFHNAAEPLSIGIVVVLISYFSLIFGELVPKTVGLQYADRMALHVAKPINFMARVTGVVVSFL
TLSNRAVLAVLGIKAEGDQAFVTPEEVQHIVAEGHEAGVFSSTEQEFIRNIFDFTHTCVREVMVPRTRVVALDLGLSRDE
LVNTVLENKYSRYPVYRESIENVTGFIHGKDLLGGIVTDPAFDIKSIIRPPFYVPEGKKVNELLKEMQRKRIHMALVVDE
YGGISGLATTEDLLEELVGEIEDEHDIGEPGSIQRLPDGSLLVDALVSISDLAEHLEIKLGDDIPYDTLAGLILDRLGRF
PEKGERVEWDRFTLICEEVKKTAVVKVRIVETVPSDSGHEEDGDVKV
>Mature_447_residues
MESVLGELAVIFLLILGNGFFAGSELAIISARKSRIAQLVAAGDPKAKIVEQLQDDPHRFLATVQIGVTLVGSLASAVGG
ATAVRYLKPLLEGSSIKFFHNAAEPLSIGIVVVLISYFSLIFGELVPKTVGLQYADRMALHVAKPINFMARVTGVVVSFL
TLSNRAVLAVLGIKAEGDQAFVTPEEVQHIVAEGHEAGVFSSTEQEFIRNIFDFTHTCVREVMVPRTRVVALDLGLSRDE
LVNTVLENKYSRYPVYRESIENVTGFIHGKDLLGGIVTDPAFDIKSIIRPPFYVPEGKKVNELLKEMQRKRIHMALVVDE
YGGISGLATTEDLLEELVGEIEDEHDIGEPGSIQRLPDGSLLVDALVSISDLAEHLEIKLGDDIPYDTLAGLILDRLGRF
PEKGERVEWDRFTLICEEVKKTAVVKVRIVETVPSDSGHEEDGDVKV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=374, Percent_Identity=29.4117647058824, Blast_Score=211, Evalue=1e-54,
Organism=Escherichia coli, GI145693175, Length=424, Percent_Identity=24.7641509433962, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790664, Length=414, Percent_Identity=26.0869565217391, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1786879, Length=254, Percent_Identity=31.496062992126, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082033, Length=334, Percent_Identity=26.3473053892216, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788119, Length=344, Percent_Identity=26.453488372093, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48920; Mature: 48920

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESVLGELAVIFLLILGNGFFAGSELAIISARKSRIAQLVAAGDPKAKIVEQLQDDPHRF
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
LATVQIGVTLVGSLASAVGGATAVRYLKPLLEGSSIKFFHNAAEPLSIGIVVVLISYFSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHH
IFGELVPKTVGLQYADRMALHVAKPINFMARVTGVVVSFLTLSNRAVLAVLGIKAEGDQA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCC
FVTPEEVQHIVAEGHEAGVFSSTEQEFIRNIFDFTHTCVREVMVPRTRVVALDLGLSRDE
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
LVNTVLENKYSRYPVYRESIENVTGFIHGKDLLGGIVTDPAFDIKSIIRPPFYVPEGKKV
HHHHHHHCCHHCCCHHHHHHHHHHHHEECHHHHCHHHCCCCHHHHHHCCCCCCCCCCCHH
NELLKEMQRKRIHMALVVDEYGGISGLATTEDLLEELVGEIEDEHDIGEPGSIQRLPDGS
HHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
LLVDALVSISDLAEHLEIKLGDDIPYDTLAGLILDRLGRFPEKGERVEWDRFTLICEEVK
HHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
KTAVVKVRIVETVPSDSGHEEDGDVKV
HHHEEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MESVLGELAVIFLLILGNGFFAGSELAIISARKSRIAQLVAAGDPKAKIVEQLQDDPHRF
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
LATVQIGVTLVGSLASAVGGATAVRYLKPLLEGSSIKFFHNAAEPLSIGIVVVLISYFSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHH
IFGELVPKTVGLQYADRMALHVAKPINFMARVTGVVVSFLTLSNRAVLAVLGIKAEGDQA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCC
FVTPEEVQHIVAEGHEAGVFSSTEQEFIRNIFDFTHTCVREVMVPRTRVVALDLGLSRDE
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
LVNTVLENKYSRYPVYRESIENVTGFIHGKDLLGGIVTDPAFDIKSIIRPPFYVPEGKKV
HHHHHHHCCHHCCCHHHHHHHHHHHHEECHHHHCHHHCCCCHHHHHHCCCCCCCCCCCHH
NELLKEMQRKRIHMALVVDEYGGISGLATTEDLLEELVGEIEDEHDIGEPGSIQRLPDGS
HHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
LLVDALVSISDLAEHLEIKLGDDIPYDTLAGLILDRLGRFPEKGERVEWDRFTLICEEVK
HHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
KTAVVKVRIVETVPSDSGHEEDGDVKV
HHHEEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]