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The map label for this gene is pab [H]

Identifier: 78188400

GI number: 78188400

Start: 495126

End: 496898

Strand: Reverse

Name: pab [H]

Synonym: Cag_0422

Alternate gene names: 78188400

Gene position: 496898-495126 (Counterclockwise)

Preceding gene: 78188401

Following gene: 78188399

Centisome position: 19.32

GC content: 49.97

Gene sequence:

>1773_bases
ATGCTGTTTCATAACCCACATGAAGTGTTGATGCTGAATGCGTTCGATGGAGTAGAAGATTTTTTTAAGAAGATAGAAGA
GAGGGTTGCGGCAGGATTTTTTGTGGCGGGATGGTTAAGCTATGAAGCTGCCTACGGCATGGATAGCGCACTTGCCGAAA
TGGCAACGGCGCAAACGTGGCAAGCGCCACTTGCGTGGTTTGGGGTATATAAAGCACCACAACGCTTTACGGCTGATGAG
GTGGCACAACTCTTTCCACCATCCTTAACGACTGCCATTACAGCACCGCATTGTTCTACCACTGAGATTGACCATGCCGA
GCAAGTTGCCGCTATTCGAGAAGAGATTGCGGCTGGCAAGGTGTATCAAGTCAACTTGACTGCTCGCTATCACTTTAGCA
TGGCGGGAGAGGCACCTGCGCTTTTTGCAGCGCTGCGCCAACAGCAACCCGCCTCCTACACGGCATTTCTTAATTGCGGA
GAACGCACCATCCTCTCCTTTTCACCTGAACTTTTTTTCCGAACTGATGGCTGCGCCATTGAAACGCGCCCCATGAAAGG
CACTGCACCTCGTGGCAGTTCAGCGGAAGAAGATGCCCATTTGCGCTTGCAGCTTCAGCAATGCGAAAAAAATTGTGCCG
AAAACTTGATGATTGTGGACTTGCTCCGCAACGATTTAGGGAGAATTTGTACCCCCGCCACCATTAAAGCTACGAAGCTT
TTTGCTACCGAAAGCTGGCCTACGCTTCACCAAATGATCTCCACAATTTCGGGTGAACTGCGCAATAACGTCAGTTTATA
CGAACTTTTTCAAGCGCTCTACCCCTGCGGCTCCATTACAGGAGCACCAAAAATAAGCGCCATGCAGTTAATTCAGCAGC
TTGAACAATCGCCACGCGGCATTTATACAGGCGCTATTGGCTACATAACGCCGCCATCAGCTCAAGTATCTGCACAAACC
ATGCGCTTTAGCGTAGCAATCCGCACCCTTGAGCTGCAAGGGCAGCACGGCATCTATGGCTCTGGTGGAGGTATTGTGTG
GGATTCCGTTGCGGCTGATGAGTATTGCGAATGCCAACTCAAAACTAAAATTCTTGAGAGCATTGCCGCCCCACCATTTG
AACTGTTTGAAACCATGCTGTGGCATGATGGATGCTACCTCTGGCTTAATGAACACCTCAATCGCCTTGCGAACTCAGCC
AAAGCACTTGGCTTTGCATTTGAACGTCAAGCAACATTGCAGCAACTTCTTGCCTTTGAAGTGGAACTGCAACAGTCCCC
AAAAAAACGCTGTAAAGTAAAACTCACCCTTTTTCGCAATGGTGAAGTACAGCTTGATGCCGAAGCCGTTTCGCCTGACT
TATCAGGGCGCTTGATGCTTGTAACGCTTGCAGAAAAGCCTGTTTCGAGCAATGAAGAGGCGTGGCTTCAGCACAAAACA
ACCTTGCGCCACTCGTATGACAGCGCATTTGCCGCTGCCCGTGCGGCTGGCTACGACGAGGTTATTTTTTGCAACCAACG
TGGCGAAATTACGGAAGGCGCAATCAGCTCAATTATGGTGCGGCACGGCTCCCAACTTCTTACGCCATCACTTGCTTGTG
GGCTGCTCAACAGCATTAGCCGTCGCTACCTGCTTGCCACCCGCCCAAATTTGCGTGAAGCCACTCTGTACCCCAATGAC
CTTGTTACTGCCGACATGCTCTATATTGCAAACTCCGTGCGCGGCATTCGCCCAGCAGTAATGGAGCAAGAAATGAAACG
TATAGAAAAATAA

Upstream 100 bases:

>100_bases
CAAGCAACCAGCTCCCCCTCCTTTCCACCATCCCGCGTTGCCGCTTCAGCAACATGGAACGCTTTGGTTGGAATCATCAT
TTTGCGACAATGGTGGGGGC

Downstream 100 bases:

>100_bases
ACCAAATGTGTTAATGACGAAACGAAGTTAAGAATCCATTTTACAGTCCAACAAACAGCCGCTAAATTGTATGGATGTTT
CGCTTTGCTGCGGCATAACA

Product: Para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MLFHNPHEVLMLNAFDGVEDFFKKIEERVAAGFFVAGWLSYEAAYGMDSALAEMATAQTWQAPLAWFGVYKAPQRFTADE
VAQLFPPSLTTAITAPHCSTTEIDHAEQVAAIREEIAAGKVYQVNLTARYHFSMAGEAPALFAALRQQQPASYTAFLNCG
ERTILSFSPELFFRTDGCAIETRPMKGTAPRGSSAEEDAHLRLQLQQCEKNCAENLMIVDLLRNDLGRICTPATIKATKL
FATESWPTLHQMISTISGELRNNVSLYELFQALYPCGSITGAPKISAMQLIQQLEQSPRGIYTGAIGYITPPSAQVSAQT
MRFSVAIRTLELQGQHGIYGSGGGIVWDSVAADEYCECQLKTKILESIAAPPFELFETMLWHDGCYLWLNEHLNRLANSA
KALGFAFERQATLQQLLAFEVELQQSPKKRCKVKLTLFRNGEVQLDAEAVSPDLSGRLMLVTLAEKPVSSNEEAWLQHKT
TLRHSYDSAFAAARAAGYDEVIFCNQRGEITEGAISSIMVRHGSQLLTPSLACGLLNSISRRYLLATRPNLREATLYPND
LVTADMLYIANSVRGIRPAVMEQEMKRIEK

Sequences:

>Translated_590_residues
MLFHNPHEVLMLNAFDGVEDFFKKIEERVAAGFFVAGWLSYEAAYGMDSALAEMATAQTWQAPLAWFGVYKAPQRFTADE
VAQLFPPSLTTAITAPHCSTTEIDHAEQVAAIREEIAAGKVYQVNLTARYHFSMAGEAPALFAALRQQQPASYTAFLNCG
ERTILSFSPELFFRTDGCAIETRPMKGTAPRGSSAEEDAHLRLQLQQCEKNCAENLMIVDLLRNDLGRICTPATIKATKL
FATESWPTLHQMISTISGELRNNVSLYELFQALYPCGSITGAPKISAMQLIQQLEQSPRGIYTGAIGYITPPSAQVSAQT
MRFSVAIRTLELQGQHGIYGSGGGIVWDSVAADEYCECQLKTKILESIAAPPFELFETMLWHDGCYLWLNEHLNRLANSA
KALGFAFERQATLQQLLAFEVELQQSPKKRCKVKLTLFRNGEVQLDAEAVSPDLSGRLMLVTLAEKPVSSNEEAWLQHKT
TLRHSYDSAFAAARAAGYDEVIFCNQRGEITEGAISSIMVRHGSQLLTPSLACGLLNSISRRYLLATRPNLREATLYPND
LVTADMLYIANSVRGIRPAVMEQEMKRIEK
>Mature_590_residues
MLFHNPHEVLMLNAFDGVEDFFKKIEERVAAGFFVAGWLSYEAAYGMDSALAEMATAQTWQAPLAWFGVYKAPQRFTADE
VAQLFPPSLTTAITAPHCSTTEIDHAEQVAAIREEIAAGKVYQVNLTARYHFSMAGEAPALFAALRQQQPASYTAFLNCG
ERTILSFSPELFFRTDGCAIETRPMKGTAPRGSSAEEDAHLRLQLQQCEKNCAENLMIVDLLRNDLGRICTPATIKATKL
FATESWPTLHQMISTISGELRNNVSLYELFQALYPCGSITGAPKISAMQLIQQLEQSPRGIYTGAIGYITPPSAQVSAQT
MRFSVAIRTLELQGQHGIYGSGGGIVWDSVAADEYCECQLKTKILESIAAPPFELFETMLWHDGCYLWLNEHLNRLANSA
KALGFAFERQATLQQLLAFEVELQQSPKKRCKVKLTLFRNGEVQLDAEAVSPDLSGRLMLVTLAEKPVSSNEEAWLQHKT
TLRHSYDSAFAAARAAGYDEVIFCNQRGEITEGAISSIMVRHGSQLLTPSLACGLLNSISRRYLLATRPNLREATLYPND
LVTADMLYIANSVRGIRPAVMEQEMKRIEK

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=277, Percent_Identity=37.9061371841155, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1787518, Length=316, Percent_Identity=30.379746835443, Blast_Score=145, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6320935, Length=258, Percent_Identity=33.3333333333333, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6324361, Length=293, Percent_Identity=26.2798634812287, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 65391; Mature: 65391

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFHNPHEVLMLNAFDGVEDFFKKIEERVAAGFFVAGWLSYEAAYGMDSALAEMATAQTW
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QAPLAWFGVYKAPQRFTADEVAQLFPPSLTTAITAPHCSTTEIDHAEQVAAIREEIAAGK
HCHHHHHHHHCCCCCCCHHHHHHHCCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHCCC
VYQVNLTARYHFSMAGEAPALFAALRQQQPASYTAFLNCGERTILSFSPELFFRTDGCAI
EEEEEEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCEEEEECCCEE
ETRPMKGTAPRGSSAEEDAHLRLQLQQCEKNCAENLMIVDLLRNDLGRICTPATIKATKL
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHCCCCCEEEEEEE
FATESWPTLHQMISTISGELRNNVSLYELFQALYPCGSITGAPKISAMQLIQQLEQSPRG
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
IYTGAIGYITPPSAQVSAQTMRFSVAIRTLELQGQHGIYGSGGGIVWDSVAADEYCECQL
EEECCCCCCCCCCCCHHHHHEEEEEEEEEEEECCCCCEEECCCCEEECCCCCCHHHHHHH
KTKILESIAAPPFELFETMLWHDGCYLWLNEHLNRLANSAKALGFAFERQATLQQLLAFE
HHHHHHHHCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VELQQSPKKRCKVKLTLFRNGEVQLDAEAVSPDLSGRLMLVTLAEKPVSSNEEAWLQHKT
HHHHCCCCCCCEEEEEEEECCCEEEEHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHH
TLRHSYDSAFAAARAAGYDEVIFCNQRGEITEGAISSIMVRHGSQLLTPSLACGLLNSIS
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHCCHHHHHHHHHHHH
RRYLLATRPNLREATLYPNDLVTADMLYIANSVRGIRPAVMEQEMKRIEK
HCEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLFHNPHEVLMLNAFDGVEDFFKKIEERVAAGFFVAGWLSYEAAYGMDSALAEMATAQTW
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QAPLAWFGVYKAPQRFTADEVAQLFPPSLTTAITAPHCSTTEIDHAEQVAAIREEIAAGK
HCHHHHHHHHCCCCCCCHHHHHHHCCCCHHHEEECCCCCCCCCCHHHHHHHHHHHHHCCC
VYQVNLTARYHFSMAGEAPALFAALRQQQPASYTAFLNCGERTILSFSPELFFRTDGCAI
EEEEEEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCEEEEECCCEE
ETRPMKGTAPRGSSAEEDAHLRLQLQQCEKNCAENLMIVDLLRNDLGRICTPATIKATKL
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHCCCCCEEEEEEE
FATESWPTLHQMISTISGELRNNVSLYELFQALYPCGSITGAPKISAMQLIQQLEQSPRG
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCC
IYTGAIGYITPPSAQVSAQTMRFSVAIRTLELQGQHGIYGSGGGIVWDSVAADEYCECQL
EEECCCCCCCCCCCCHHHHHEEEEEEEEEEEECCCCCEEECCCCEEECCCCCCHHHHHHH
KTKILESIAAPPFELFETMLWHDGCYLWLNEHLNRLANSAKALGFAFERQATLQQLLAFE
HHHHHHHHCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VELQQSPKKRCKVKLTLFRNGEVQLDAEAVSPDLSGRLMLVTLAEKPVSSNEEAWLQHKT
HHHHCCCCCCCEEEEEEEECCCEEEEHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHH
TLRHSYDSAFAAARAAGYDEVIFCNQRGEITEGAISSIMVRHGSQLLTPSLACGLLNSIS
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHCCHHHHHHHHHHHH
RRYLLATRPNLREATLYPNDLVTADMLYIANSVRGIRPAVMEQEMKRIEK
HCEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]