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The map label for this gene is accD

Identifier: 78188270

GI number: 78188270

Start: 315655

End: 316494

Strand: Reverse

Name: accD

Synonym: Cag_0289

Alternate gene names: 78188270

Gene position: 316494-315655 (Counterclockwise)

Preceding gene: 78188274

Following gene: 78188266

Centisome position: 12.3

GC content: 45.12

Gene sequence:

>840_bases
ATGTCTTGGTTCAATCGAGTAAAACCCTCCATCAGCTCAACCGCTAAACGCGACGTGCCTGAAGGATTGTGGTGGAAATG
CGAAGAGTGCGGCGCAGCACTTCATAAAAAACAAATGGAAGCTTCCGACCACACCTGTCCTCAATGTGGTTACCATTTTA
GAATTTCACCTTACAAATATTTTTCATTGCTTTTTGACAATCAAAAATATGTAGAGTTTGATGACCATTTGCGTGCCGCC
GATCCTTTACATTTTGTTGATACAAAAAAATATCCCGATCGCGTAAGCGACACCATTGAAAAAAGTGGCAAAACCGAAGC
CTGCCGCAATGCGCATGGCTTATGTGGGGGCGAAACATTGGTGATTTCAGCTATGGACTTTAGCTTTATTGGTGGCTCCA
TGGGCTCGGTTGTGGGTGAAAAAATTTCCCGCGCGGTAGATAAAGCTATTGAACTGCAATCGCCATTACTCGTCATTTCG
CAATCGGGTGGCGCTCGCATGATGGAAGGAGCCTTTAGCTTAATGCAAATGGCAAAAACTGCCGCAAAACTCTCGCTTTT
AAGCGAACATCGCCTGCCCTACATTTCGCTTATGACCGATCCCACAATGGGCGGTATTACCGCATCGTTTGCCATGTTGG
GCGACATCAATATTAGCGAACCCAAAGCACTCATTGGTTTTGCTGGACCTCGCGTTATTCGTGATACCATTAAGCGCGAC
TTACCTGAAGGCTTTCAACGGGCAGAATTTTTGTTAGAGCATGGATTTATTGACCGCATTATTCCCCGCCGTGAATTGAA
AAGCGATCTTACAACACTCCTTAGTTTAATGAAGCTGTAA

Upstream 100 bases:

>100_bases
CGGCGTTTGCATCACGTACAACGGATGCCTTGCATGTTGAATCGTAGGGAAGCTCACCTCAACAATGCAGTGATAATGTA
ATTAATTATTCCCCCTTGTT

Downstream 100 bases:

>100_bases
AGGATTGTTGCTCAATATTTTGACTTGCCACCATGCCGCTACTCTCAAAAAGGGATAGCGGCATTTTTTATGGTAATATC
GTATCAATCTCATATTGACT

Product: Acetyl-CoA carboxylase carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MSWFNRVKPSISSTAKRDVPEGLWWKCEECGAALHKKQMEASDHTCPQCGYHFRISPYKYFSLLFDNQKYVEFDDHLRAA
DPLHFVDTKKYPDRVSDTIEKSGKTEACRNAHGLCGGETLVISAMDFSFIGGSMGSVVGEKISRAVDKAIELQSPLLVIS
QSGGARMMEGAFSLMQMAKTAAKLSLLSEHRLPYISLMTDPTMGGITASFAMLGDINISEPKALIGFAGPRVIRDTIKRD
LPEGFQRAEFLLEHGFIDRIIPRRELKSDLTTLLSLMKL

Sequences:

>Translated_279_residues
MSWFNRVKPSISSTAKRDVPEGLWWKCEECGAALHKKQMEASDHTCPQCGYHFRISPYKYFSLLFDNQKYVEFDDHLRAA
DPLHFVDTKKYPDRVSDTIEKSGKTEACRNAHGLCGGETLVISAMDFSFIGGSMGSVVGEKISRAVDKAIELQSPLLVIS
QSGGARMMEGAFSLMQMAKTAAKLSLLSEHRLPYISLMTDPTMGGITASFAMLGDINISEPKALIGFAGPRVIRDTIKRD
LPEGFQRAEFLLEHGFIDRIIPRRELKSDLTTLLSLMKL
>Mature_278_residues
SWFNRVKPSISSTAKRDVPEGLWWKCEECGAALHKKQMEASDHTCPQCGYHFRISPYKYFSLLFDNQKYVEFDDHLRAAD
PLHFVDTKKYPDRVSDTIEKSGKTEACRNAHGLCGGETLVISAMDFSFIGGSMGSVVGEKISRAVDKAIELQSPLLVISQ
SGGARMMEGAFSLMQMAKTAAKLSLLSEHRLPYISLMTDPTMGGITASFAMLGDINISEPKALIGFAGPRVIRDTIKRDL
PEGFQRAEFLLEHGFIDRIIPRRELKSDLTTLLSLMKL

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Homo sapiens, GI119943100, Length=192, Percent_Identity=25.5208333333333, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1788655, Length=280, Percent_Identity=49.2857142857143, Blast_Score=288, Evalue=3e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_CHLCH (Q3ATW0)

Other databases:

- EMBL:   CP000108
- RefSeq:   YP_378608.1
- ProteinModelPortal:   Q3ATW0
- SMR:   Q3ATW0
- STRING:   Q3ATW0
- GeneID:   3748118
- GenomeReviews:   CP000108_GR
- KEGG:   cch:Cag_0289
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   CLSK637819
- BioCyc:   CCHL340177:CAG_0289-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 31086; Mature: 30955

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWFNRVKPSISSTAKRDVPEGLWWKCEECGAALHKKQMEASDHTCPQCGYHFRISPYKY
CCHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHH
FSLLFDNQKYVEFDDHLRAADPLHFVDTKKYPDRVSDTIEKSGKTEACRNAHGLCGGETL
HHHHCCCCCEECHHHHHCCCCCCHHHCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCEE
VISAMDFSFIGGSMGSVVGEKISRAVDKAIELQSPLLVISQSGGARMMEGAFSLMQMAKT
EEEECHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
AAKLSLLSEHRLPYISLMTDPTMGGITASFAMLGDINISEPKALIGFAGPRVIRDTIKRD
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
LPEGFQRAEFLLEHGFIDRIIPRRELKSDLTTLLSLMKL
HHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SWFNRVKPSISSTAKRDVPEGLWWKCEECGAALHKKQMEASDHTCPQCGYHFRISPYKY
CHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHH
FSLLFDNQKYVEFDDHLRAADPLHFVDTKKYPDRVSDTIEKSGKTEACRNAHGLCGGETL
HHHHCCCCCEECHHHHHCCCCCCHHHCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCCCEE
VISAMDFSFIGGSMGSVVGEKISRAVDKAIELQSPLLVISQSGGARMMEGAFSLMQMAKT
EEEECHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
AAKLSLLSEHRLPYISLMTDPTMGGITASFAMLGDINISEPKALIGFAGPRVIRDTIKRD
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
LPEGFQRAEFLLEHGFIDRIIPRRELKSDLTTLLSLMKL
HHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA