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The map label for this gene is clpX

Identifier: 78188166

GI number: 78188166

Start: 206164

End: 207495

Strand: Reverse

Name: clpX

Synonym: Cag_0183

Alternate gene names: 78188166

Gene position: 207495-206164 (Counterclockwise)

Preceding gene: 78188167

Following gene: 78188165

Centisome position: 8.07

GC content: 45.87

Gene sequence:

>1332_bases
ATGAAAACACAAGAACCGGGAAAAGGTAGAACTCGCACGAATAAAAACGATACAGCAAATGTTTTTTGCTCATTTTGTGG
GCGTCCAGCTTACGAAGTTGGTAGCATGGTTGCAGGACCGAACGTCTTTATTTGCGACCGCTGCATAGCCGCTGCAAACG
ATGTGCTTTTACACCAAACAGGCAACGCACCACAACCTCAGCAACCAGAACCATCGGCACCCATCTCCAATCAACCATTT
TTTCCCCGCCTTGTTAGCCCCAAAGCTATTGTAGATGTGCTCGACCAATATGTTGTTGGGCAAGAACGTGCTAAAAAATC
GCTTGCCGTAGCCGTCTATAACCACTACAAGCGCATTGAATCGCACAATACAAGTGCCGCATTAGATGAAGTGGTGATTG
AAAAAAGCAACATTTTGCTTTTGGGACCAACAGGCACCGGAAAAACCTTGCTTGCCCAAACGCTTGCAAATTTGCTTGAT
GTGCCATTCTCCATTGTTGATGCCACCTCGCTTACCGAAGCAGGATATGTTGGCGATGACGTTGAAACCATTCTTGCACG
CCTACTACACGCCTCCGACTTTGACCTTGAGCGCACCGAACGCGGCATTATTTATGTTGATGAAATTGATAAAATTGCCC
GCAAATCAGCCAACGTTTCCATTACACGCGACGTTTCAGGCGAAGGCGTTCAGCAAGGATTATTAAAAATTCTTGAAGGC
GCGGTTGTTGGCGTTCCCCCAAAAGGCGGACGCAAGCACCCCGAACAACCACTCATTAACGTTAACACCAAAAACATCCT
CTTTATTTGTGGAGGAGCTTTTGAAGGCATTGATAAGATTATTGCACGCCGCGTTTCAAAATCATCCATGGGCTTTGGCG
CTAAAGTAAAAAGCAGCAGCATGGATTACGATCCTGATATTTTACGCCAAGTAATGCAAGACGATCTGCACGAATATGGG
CTAATCCCAGAGTTTATTGGTCGCCTACCCGTTATTTCAACGCTTGATATGCTTGATGAAAAAGCGCTGCACAACATTTT
AGTAGAACCAAAAAACGCCATTACCAAGCAGTACAAAAAGCTCTTTGATATGGATGGCGTAGAGCTTGAATTTACCGATG
AAGCGCTTGAAAAGGTAGTGAACATTGCCAAAGAGCGAGGCACAGGCGCACGCGCCCTCCGCTCAGTGCTTGAAAGTGTG
ATGATTGACATTATGTACGAAATTCCCTCAATGAAGGAGACGCACAAGTGCATTGTTACGGCTGAAACCATTGAACAAAA
AACGCCGCCCGAGTACATCAGCGAAGCCAATACCACCAAGAAAAGTGCATAA

Upstream 100 bases:

>100_bases
CTTGCTATCAAGGAGAAAATCCACCAGCCACTTATACGGCACTCCCATCTCCTTGAAGCACAACAAAATTCAATACAGAG
AGACAATCCACGACACACGA

Downstream 100 bases:

>100_bases
CATAGAGCTTTGGCATTGTAACCCTAAAGCCATATATTAGAAGCCTTTTGCGGCACTTGGGCGGTTAGCTCAGTTGGTTA
GAGCGCTACCTTGACACGGT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKTQEPGKGRTRTNKNDTANVFCSFCGRPAYEVGSMVAGPNVFICDRCIAAANDVLLHQTGNAPQPQQPEPSAPISNQPF
FPRLVSPKAIVDVLDQYVVGQERAKKSLAVAVYNHYKRIESHNTSAALDEVVIEKSNILLLGPTGTGKTLLAQTLANLLD
VPFSIVDATSLTEAGYVGDDVETILARLLHASDFDLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQGLLKILEG
AVVGVPPKGGRKHPEQPLINVNTKNILFICGGAFEGIDKIIARRVSKSSMGFGAKVKSSSMDYDPDILRQVMQDDLHEYG
LIPEFIGRLPVISTLDMLDEKALHNILVEPKNAITKQYKKLFDMDGVELEFTDEALEKVVNIAKERGTGARALRSVLESV
MIDIMYEIPSMKETHKCIVTAETIEQKTPPEYISEANTTKKSA

Sequences:

>Translated_443_residues
MKTQEPGKGRTRTNKNDTANVFCSFCGRPAYEVGSMVAGPNVFICDRCIAAANDVLLHQTGNAPQPQQPEPSAPISNQPF
FPRLVSPKAIVDVLDQYVVGQERAKKSLAVAVYNHYKRIESHNTSAALDEVVIEKSNILLLGPTGTGKTLLAQTLANLLD
VPFSIVDATSLTEAGYVGDDVETILARLLHASDFDLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQGLLKILEG
AVVGVPPKGGRKHPEQPLINVNTKNILFICGGAFEGIDKIIARRVSKSSMGFGAKVKSSSMDYDPDILRQVMQDDLHEYG
LIPEFIGRLPVISTLDMLDEKALHNILVEPKNAITKQYKKLFDMDGVELEFTDEALEKVVNIAKERGTGARALRSVLESV
MIDIMYEIPSMKETHKCIVTAETIEQKTPPEYISEANTTKKSA
>Mature_443_residues
MKTQEPGKGRTRTNKNDTANVFCSFCGRPAYEVGSMVAGPNVFICDRCIAAANDVLLHQTGNAPQPQQPEPSAPISNQPF
FPRLVSPKAIVDVLDQYVVGQERAKKSLAVAVYNHYKRIESHNTSAALDEVVIEKSNILLLGPTGTGKTLLAQTLANLLD
VPFSIVDATSLTEAGYVGDDVETILARLLHASDFDLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQGLLKILEG
AVVGVPPKGGRKHPEQPLINVNTKNILFICGGAFEGIDKIIARRVSKSSMGFGAKVKSSSMDYDPDILRQVMQDDLHEYG
LIPEFIGRLPVISTLDMLDEKALHNILVEPKNAITKQYKKLFDMDGVELEFTDEALEKVVNIAKERGTGARALRSVLESV
MIDIMYEIPSMKETHKCIVTAETIEQKTPPEYISEANTTKKSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=328, Percent_Identity=47.2560975609756, Blast_Score=296, Evalue=3e-80,
Organism=Escherichia coli, GI1786642, Length=415, Percent_Identity=53.4939759036145, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1790366, Length=213, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71988663, Length=393, Percent_Identity=39.1857506361323, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71982905, Length=292, Percent_Identity=43.4931506849315, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI71982908, Length=292, Percent_Identity=43.4931506849315, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=253, Percent_Identity=41.897233201581, Blast_Score=184, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6319704, Length=415, Percent_Identity=38.5542168674699, Blast_Score=254, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24648291, Length=325, Percent_Identity=43.6923076923077, Blast_Score=284, Evalue=8e-77,
Organism=Drosophila melanogaster, GI24648289, Length=325, Percent_Identity=43.6923076923077, Blast_Score=284, Evalue=9e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 48521; Mature: 48521

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQEPGKGRTRTNKNDTANVFCSFCGRPAYEVGSMVAGPNVFICDRCIAAANDVLLHQT
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCHHCCCCEEEHHHHHHHHCCEEEECC
GNAPQPQQPEPSAPISNQPFFPRLVSPKAIVDVLDQYVVGQERAKKSLAVAVYNHYKRIE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
SHNTSAALDEVVIEKSNILLLGPTGTGKTLLAQTLANLLDVPFSIVDATSLTEAGYVGDD
CCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
VETILARLLHASDFDLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQGLLKILEG
HHHHHHHHHHCCCCCHHHHCCCEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCC
AVVGVPPKGGRKHPEQPLINVNTKNILFICGGAFEGIDKIIARRVSKSSMGFGAKVKSSS
CEEECCCCCCCCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEECCCC
MDYDPDILRQVMQDDLHEYGLIPEFIGRLPVISTLDMLDEKALHNILVEPKNAITKQYKK
CCCCHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LFDMDGVELEFTDEALEKVVNIAKERGTGARALRSVLESVMIDIMYEIPSMKETHKCIVT
HHCCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEE
AETIEQKTPPEYISEANTTKKSA
HHHHHCCCCHHHHHCCCCCCCCC
>Mature Secondary Structure
MKTQEPGKGRTRTNKNDTANVFCSFCGRPAYEVGSMVAGPNVFICDRCIAAANDVLLHQT
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCHHCCCCEEEHHHHHHHHCCEEEECC
GNAPQPQQPEPSAPISNQPFFPRLVSPKAIVDVLDQYVVGQERAKKSLAVAVYNHYKRIE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
SHNTSAALDEVVIEKSNILLLGPTGTGKTLLAQTLANLLDVPFSIVDATSLTEAGYVGDD
CCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
VETILARLLHASDFDLERTERGIIYVDEIDKIARKSANVSITRDVSGEGVQQGLLKILEG
HHHHHHHHHHCCCCCHHHHCCCEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCC
AVVGVPPKGGRKHPEQPLINVNTKNILFICGGAFEGIDKIIARRVSKSSMGFGAKVKSSS
CEEECCCCCCCCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEECCCC
MDYDPDILRQVMQDDLHEYGLIPEFIGRLPVISTLDMLDEKALHNILVEPKNAITKQYKK
CCCCHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LFDMDGVELEFTDEALEKVVNIAKERGTGARALRSVLESVMIDIMYEIPSMKETHKCIVT
HHCCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEE
AETIEQKTPPEYISEANTTKKSA
HHHHHCCCCHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA