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The map label for this gene is can [H]

Identifier: 78067054

GI number: 78067054

Start: 2683053

End: 2683694

Strand: Direct

Name: can [H]

Synonym: Bcep18194_A5585

Alternate gene names: 78067054

Gene position: 2683053-2683694 (Clockwise)

Preceding gene: 78067053

Following gene: 78067055

Centisome position: 72.63

GC content: 71.18

Gene sequence:

>642_bases
ATGAATCGCCCCAAGAGCATGCTGGTTGCCAACATCGCCTGGGCCCGCGAAACGCGTGAATACACGCCCGGCTTCTTCGA
CGCGCTCGCGCGCGGCCAGAACCCGCGCGTGCTGTGGATCGGCTGCGCCGACAGCCGCGTGCCGGCCGAAACCATCACGC
ACTGCGCGCCCGGCGAGCTGTTCGTCCATCGCAACATCGCGAACCTGTTCCATCCCGACGACGACAATTCCGCCAGCGTG
CTGGAGTACGCGGTGCGCGTGCTGCAGGTCGACCACGTGATCGTGTGCGGGCACTACGGATGCGGCGGCGTACGCGCGTC
GCTGCTGCCGCCGCCGTCCGACCTGCCGCACGTCGCGCGCCGCATCGCGCCGCTCTGCGCGCTCGCGCGGCGCCATCGCG
ACGCGCTGGACGGGCTCGACGACACGGCCGCCGCCGATCGCCTCGCCGAGCTCAACGTGCTCGAACAGGTGCGGCTGCTG
CGCGCGTCGCCGATCGTGCAAGGCCGCGAACGGCCGCCGCTCGTGCACGGCTGGATCTTCTCGCTCGCCGACGGCCGCCT
GCAGGAACTCGACTCCGGCTACACCAACCCGCCCGTCGACGTCGAAACCATGCAGGCCGCGACGGCCGGTGCGCTCGGCT
GA

Upstream 100 bases:

>100_bases
TACCCCTAATATCAGTCGAAACCAAACCTTTCAATTTAGAAAGAATGCCATTGCGTCATTTCTGCCGATATTCGTTTGCC
TTTATCACAAAGGAGTCCTC

Downstream 100 bases:

>100_bases
TCTACCCCGCCCCCAAGCCAATGAAATCGCCCCAACCATGAAACTGAACGAGCGCCTGTCCACCCTGCCGCGCGACATCG
TCGCCGGCGTCGTCGTTTTC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MNRPKSMLVANIAWARETREYTPGFFDALARGQNPRVLWIGCADSRVPAETITHCAPGELFVHRNIANLFHPDDDNSASV
LEYAVRVLQVDHVIVCGHYGCGGVRASLLPPPSDLPHVARRIAPLCALARRHRDALDGLDDTAAADRLAELNVLEQVRLL
RASPIVQGRERPPLVHGWIFSLADGRLQELDSGYTNPPVDVETMQAATAGALG

Sequences:

>Translated_213_residues
MNRPKSMLVANIAWARETREYTPGFFDALARGQNPRVLWIGCADSRVPAETITHCAPGELFVHRNIANLFHPDDDNSASV
LEYAVRVLQVDHVIVCGHYGCGGVRASLLPPPSDLPHVARRIAPLCALARRHRDALDGLDDTAAADRLAELNVLEQVRLL
RASPIVQGRERPPLVHGWIFSLADGRLQELDSGYTNPPVDVETMQAATAGALG
>Mature_213_residues
MNRPKSMLVANIAWARETREYTPGFFDALARGQNPRVLWIGCADSRVPAETITHCAPGELFVHRNIANLFHPDDDNSASV
LEYAVRVLQVDHVIVCGHYGCGGVRASLLPPPSDLPHVARRIAPLCALARRHRDALDGLDDTAAADRLAELNVLEQVRLL
RASPIVQGRERPPLVHGWIFSLADGRLQELDSGYTNPPVDVETMQAATAGALG

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=199, Percent_Identity=44.2211055276382, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1786534, Length=198, Percent_Identity=31.3131313131313, Blast_Score=86, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324292, Length=206, Percent_Identity=31.5533980582524, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23250; Mature: 23250

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPKSMLVANIAWARETREYTPGFFDALARGQNPRVLWIGCADSRVPAETITHCAPGEL
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCCE
FVHRNIANLFHPDDDNSASVLEYAVRVLQVDHVIVCGHYGCGGVRASLLPPPSDLPHVAR
EEECCHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCEECCCCCCCCHHHHHH
RIAPLCALARRHRDALDGLDDTAAADRLAELNVLEQVRLLRASPIVQGRERPPLVHGWIF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
SLADGRLQELDSGYTNPPVDVETMQAATAGALG
HHCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNRPKSMLVANIAWARETREYTPGFFDALARGQNPRVLWIGCADSRVPAETITHCAPGEL
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCCE
FVHRNIANLFHPDDDNSASVLEYAVRVLQVDHVIVCGHYGCGGVRASLLPPPSDLPHVAR
EEECCHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCEECCCCCCCCHHHHHH
RIAPLCALARRHRDALDGLDDTAAADRLAELNVLEQVRLLRASPIVQGRERPPLVHGWIF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
SLADGRLQELDSGYTNPPVDVETMQAATAGALG
HHCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]