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The map label for this gene is aspC [H]

Identifier: 78067008

GI number: 78067008

Start: 2633156

End: 2634355

Strand: Direct

Name: aspC [H]

Synonym: Bcep18194_A5539

Alternate gene names: 78067008

Gene position: 2633156-2634355 (Clockwise)

Preceding gene: 78067002

Following gene: 78067010

Centisome position: 71.28

GC content: 64.5

Gene sequence:

>1200_bases
ATGTCGCTCTTCTCCGCTGTCCAGCTTGCTCCCCGCGACCCGATCCTGGGCCTGAACGAAGCCTTCAACGCCGATGCGCG
TCCGACCAAGGTCAACCTCGGCGTCGGTGTGTACACGAACGAAGAAGGCAAGATTCCGCTGCTGCGCGCGGTTCGCGAAG
CAGAGAAGGTGCGTGTCGACGCCGGCCTGCCCCGCGGCTACCTGCCGATCGACGGCATCGCTGCCTACGACGCGGCCGTG
CAGAAGCTGCTGCTCGGCAACGACTCGCCGCTGATCGCAGCTGGTCGCGTGGTCACGGCCCAGGCGCTGGGCGGCACGGG
CGCACTGAAGATCGGCGCCGATTTCCTGCGCACCGTGAACCCGAACGTGAAGGTCGCGATTAGCGATCCGAGCTGGGAAA
ACCACCGCGCGCTGTTCGAAGCAGCCGGTTTCGAAGTCGTTGCGTACCCGTATTACGACGCTGCCACCAATGGCGTGAAC
TTCGAAGGCATGCTGTCGGCACTGAATAGCTACGCGGCAGGTACGGTCGTCGTGCTGCACGCGTGCTGCCACAACCCGAC
CGGCGTGGACCTGACCGAAGCGCAATGGCAACAGGTCGTCGACGTCGTGAAGGCGCGCAACCTCGTGCCGTTCCTCGACA
TGGCCTACCAGGGCTTCGGCGAGAACATCGAGGCCGATGCTGCTGCCGTGCGCCTGTTTGCCGCGGCTGACCTGAACGCA
TTCGTGTCGTCGTCGTTCTCGAAGTCGTTCTCGCTGTATGGCGAGCGCGTCGGCGCACTGTCGATCATCACGTCGAGCAA
GGAAGAGGCGACGCGCGTGCTGTCGCAACTGAAGCGCGTGATCCGCACGAACTACTCGAACCCGCCGACCCATGGCGGCG
CCGTGGTCGCAGCGGTGCTCGCATCGCCGGAACTGCACGCTTCGTGGGTGCAGGAACTCGGTGAAATGCGCGATCGTATC
CGCTCGATGCGCAATGGTCTCGTCGAGCGCCTGAAGGCAAGCGGCGTCGATCGCGACTTCAGCTTCATCAACGAGCAGCG
CGGGATGTTCTCGTATTCGGGCCTGACCTCGGCGCAAGTCGATCGCCTGCGCGACGAGTTCGGCATCTACGCAGTCGGCA
CGGGCCGGATCTGCGTCGCAGCACTGAACACGCGCAACCTCGACGCGGTCGCCAATGCGGTCGCAGCCGTCCTGAAGTAA

Upstream 100 bases:

>100_bases
GCTGCTGCGCTTTCCGGCGTCGTGCCTGCCCGCGCGCGGTCCACCGCGACCGCCCCGCCAGTTGAAAGCCTGACCCTCTT
TTCACTACTGCAGAATCATC

Downstream 100 bases:

>100_bases
CGCGGCTTGAGCGGGTGGCAGCCGTCATCGGCCCCGCCCTGCCAAAATAGAAACGCGCTCTACGGAGCGCGTTTTTTTAT
GCCATTCGCCGGCGGGCAAC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEEGKIPLLRAVREAEKVRVDAGLPRGYLPIDGIAAYDAAV
QKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVNPNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVN
FEGMLSALNSYAAGTVVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHASWVQELGEMRDRI
RSMRNGLVERLKASGVDRDFSFINEQRGMFSYSGLTSAQVDRLRDEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK

Sequences:

>Translated_399_residues
MSLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEEGKIPLLRAVREAEKVRVDAGLPRGYLPIDGIAAYDAAV
QKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVNPNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVN
FEGMLSALNSYAAGTVVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHASWVQELGEMRDRI
RSMRNGLVERLKASGVDRDFSFINEQRGMFSYSGLTSAQVDRLRDEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK
>Mature_398_residues
SLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEEGKIPLLRAVREAEKVRVDAGLPRGYLPIDGIAAYDAAVQ
KLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVNPNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNF
EGMLSALNSYAAGTVVVLHACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNAF
VSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVLASPELHASWVQELGEMRDRIR
SMRNGLVERLKASGVDRDFSFINEQRGMFSYSGLTSAQVDRLRDEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=398, Percent_Identity=43.7185929648241, Blast_Score=341, Evalue=9e-94,
Organism=Homo sapiens, GI4504067, Length=401, Percent_Identity=43.640897755611, Blast_Score=335, Evalue=6e-92,
Organism=Homo sapiens, GI117414139, Length=399, Percent_Identity=28.0701754385965, Blast_Score=176, Evalue=5e-44,
Organism=Escherichia coli, GI1790488, Length=399, Percent_Identity=54.3859649122807, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=47.7272727272727, Blast_Score=396, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI71981858, Length=400, Percent_Identity=43, Blast_Score=353, Evalue=9e-98,
Organism=Caenorhabditis elegans, GI25147133, Length=399, Percent_Identity=42.1052631578947, Blast_Score=336, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17569539, Length=402, Percent_Identity=40.2985074626866, Blast_Score=307, Evalue=6e-84,
Organism=Caenorhabditis elegans, GI17569537, Length=396, Percent_Identity=33.5858585858586, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=41.7840375586854, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17550384, Length=269, Percent_Identity=34.5724907063197, Blast_Score=180, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6323055, Length=408, Percent_Identity=37.9901960784314, Blast_Score=297, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6322743, Length=436, Percent_Identity=32.7981651376147, Blast_Score=244, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24580972, Length=400, Percent_Identity=42.5, Blast_Score=327, Evalue=8e-90,
Organism=Drosophila melanogaster, GI24580970, Length=400, Percent_Identity=42.5, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI19920542, Length=393, Percent_Identity=42.2391857506361, Blast_Score=319, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24654046, Length=402, Percent_Identity=40.547263681592, Blast_Score=311, Evalue=7e-85,
Organism=Drosophila melanogaster, GI19922362, Length=402, Percent_Identity=40.547263681592, Blast_Score=311, Evalue=7e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42694; Mature: 42563

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEEGKIPLLRAVREAEKVRVD
CCHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHEEEC
AGLPRGYLPIDGIAAYDAAVQKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVN
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCEEHHHHHHHHHCC
PNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNFEGMLSALNSYAAGTVVVLH
CCEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
ACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVL
HHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASPELHASWVQELGEMRDRIRSMRNGLVERLKASGVDRDFSFINEQRGMFSYSGLTSAQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCHHHH
DRLRDEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK
HHHHHHCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SLFSAVQLAPRDPILGLNEAFNADARPTKVNLGVGVYTNEEGKIPLLRAVREAEKVRVD
CHHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHEEEC
AGLPRGYLPIDGIAAYDAAVQKLLLGNDSPLIAAGRVVTAQALGGTGALKIGADFLRTVN
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEECCCCCCEEHHHHHHHHHCC
PNVKVAISDPSWENHRALFEAAGFEVVAYPYYDAATNGVNFEGMLSALNSYAAGTVVVLH
CCEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
ACCHNPTGVDLTEAQWQQVVDVVKARNLVPFLDMAYQGFGENIEADAAAVRLFAAADLNA
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
FVSSSFSKSFSLYGERVGALSIITSSKEEATRVLSQLKRVIRTNYSNPPTHGGAVVAAVL
HHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASPELHASWVQELGEMRDRIRSMRNGLVERLKASGVDRDFSFINEQRGMFSYSGLTSAQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCHHHH
DRLRDEFGIYAVGTGRICVAALNTRNLDAVANAVAAVLK
HHHHHHCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]