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The map label for this gene is yghZ [H]

Identifier: 78067010

GI number: 78067010

Start: 2635428

End: 2636399

Strand: Direct

Name: yghZ [H]

Synonym: Bcep18194_A5541

Alternate gene names: 78067010

Gene position: 2635428-2636399 (Clockwise)

Preceding gene: 78067008

Following gene: 78067011

Centisome position: 71.34

GC content: 64.3

Gene sequence:

>972_bases
ATGCACTATCGACGGCTAGGCCGCTCCGGCCTGCAGATCAGCGAGCTTTCGCTCGGTTCGTGGGTGACCTACGGCAACCA
GGTCGACCAGCGGGTCGCGCGCGAATGCCTGGCTGCGGCGCGCGACGCAGGCGTCAATTTCTTCGACAACGCCGAAGTCT
ACGCCGGCGGCAAATCCGAGGAAATCATGGGCCAAGCGCTCAAGTCGCTCGACTGGCCGCGCGTCAGCTATATCGTGTCC
ACGAAGTTCTTCTGGGGCCTGGCCGAAGCGCCGAACCAGTATCACACGCTGAACCGGAAGTACCTGCTGAACGCCATCGA
CGGCTCGCTGCGCCGGCTGCAACTCGACTATGTCGATCTCGTCTACTGCCATCGCCCCGACCCGAACACGCCGATCGAGG
AAACCGTCTGGGCGATGAGCGACATGATCGTACGCGGCAAGGCGCTGTACTGGGGCACGTCGGAATGGAGTGCCGACGAG
ATCCGCGCTGCGTGCGAGATCGCCGAGCGGCATCACCTGCACAAGCCCGTCGTCGAGCAGCCGCAGTACAACCTGTTCCA
TCGCACGCGGGTCGAACAGGAATACGCGCGGCTCTATGACGACTACGGTCTCGGCCTCACTACCTGGAGCCCGCTGGCAT
CGGGCCTGCTCACCGGCAAGTACCGCAACGGCGTGCCGCCAGGCAGCCGCGCACAGTTGCAGGGTTACGACTGGATGCGC
GACCGCCTGACCAATCAAGCCGCCAACGACATCGTCGAACGGCTCGGCACAATCGCAGCCGTGCTCGGATGCAGCACGGC
CCAGCTCGCGATCGCGTGGGTGCTCGCCAATCCGCGCGTGAGTTCGGTCATCACGGGTGCGTCGCGGATCGAGCAGATCC
GTGACAACATGCGCGCGCTCGACGTTGCCGAGAAGCTGACACCGGATGTGAAGCAACGCATCGAGGAGGTGGTCGGCGAC
GCGTACGAGTAA

Upstream 100 bases:

>100_bases
ATCGTACTGGCGGGCCAGCCATCATTGTGCACGATCGGCCCCGCCGTTCGCGCGCAAAACGTCTAAGCTTAAGGTCGGTT
CTGTCACGCAGGAGATTCGC

Downstream 100 bases:

>100_bases
GGCGATGCGCGGCCACTCGCGTACAATACGCGGCCCGCATCGGCGCCCGTCCTGACGGCCGCGCACGATCGACCGCTTTC
ATCGACTCACCTTTCGTTTC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MHYRRLGRSGLQISELSLGSWVTYGNQVDQRVARECLAAARDAGVNFFDNAEVYAGGKSEEIMGQALKSLDWPRVSYIVS
TKFFWGLAEAPNQYHTLNRKYLLNAIDGSLRRLQLDYVDLVYCHRPDPNTPIEETVWAMSDMIVRGKALYWGTSEWSADE
IRAACEIAERHHLHKPVVEQPQYNLFHRTRVEQEYARLYDDYGLGLTTWSPLASGLLTGKYRNGVPPGSRAQLQGYDWMR
DRLTNQAANDIVERLGTIAAVLGCSTAQLAIAWVLANPRVSSVITGASRIEQIRDNMRALDVAEKLTPDVKQRIEEVVGD
AYE

Sequences:

>Translated_323_residues
MHYRRLGRSGLQISELSLGSWVTYGNQVDQRVARECLAAARDAGVNFFDNAEVYAGGKSEEIMGQALKSLDWPRVSYIVS
TKFFWGLAEAPNQYHTLNRKYLLNAIDGSLRRLQLDYVDLVYCHRPDPNTPIEETVWAMSDMIVRGKALYWGTSEWSADE
IRAACEIAERHHLHKPVVEQPQYNLFHRTRVEQEYARLYDDYGLGLTTWSPLASGLLTGKYRNGVPPGSRAQLQGYDWMR
DRLTNQAANDIVERLGTIAAVLGCSTAQLAIAWVLANPRVSSVITGASRIEQIRDNMRALDVAEKLTPDVKQRIEEVVGD
AYE
>Mature_323_residues
MHYRRLGRSGLQISELSLGSWVTYGNQVDQRVARECLAAARDAGVNFFDNAEVYAGGKSEEIMGQALKSLDWPRVSYIVS
TKFFWGLAEAPNQYHTLNRKYLLNAIDGSLRRLQLDYVDLVYCHRPDPNTPIEETVWAMSDMIVRGKALYWGTSEWSADE
IRAACEIAERHHLHKPVVEQPQYNLFHRTRVEQEYARLYDDYGLGLTTWSPLASGLLTGKYRNGVPPGSRAQLQGYDWMR
DRLTNQAANDIVERLGTIAAVLGCSTAQLAIAWVLANPRVSSVITGASRIEQIRDNMRALDVAEKLTPDVKQRIEEVVGD
AYE

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436969, Length=323, Percent_Identity=44.8916408668731, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI4504825, Length=321, Percent_Identity=44.8598130841121, Blast_Score=304, Evalue=6e-83,
Organism=Homo sapiens, GI27436964, Length=321, Percent_Identity=45.7943925233645, Blast_Score=301, Evalue=5e-82,
Organism=Homo sapiens, GI27436962, Length=321, Percent_Identity=45.7943925233645, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI27436966, Length=321, Percent_Identity=45.4828660436137, Blast_Score=298, Evalue=4e-81,
Organism=Homo sapiens, GI27436971, Length=323, Percent_Identity=45.8204334365325, Blast_Score=290, Evalue=1e-78,
Organism=Homo sapiens, GI41152114, Length=295, Percent_Identity=29.8305084745763, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI223718702, Length=295, Percent_Identity=27.4576271186441, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41327764, Length=276, Percent_Identity=29.7101449275362, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1789375, Length=327, Percent_Identity=36.085626911315, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI87081735, Length=315, Percent_Identity=36.1904761904762, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI1788070, Length=320, Percent_Identity=30.3125, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=30.1724137931034, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788081, Length=303, Percent_Identity=25.7425742574257, Blast_Score=75, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=335, Percent_Identity=26.865671641791, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6323998, Length=330, Percent_Identity=26.969696969697, Blast_Score=93, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=304, Percent_Identity=26.9736842105263, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=341, Percent_Identity=26.3929618768328, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=226, Percent_Identity=25.6637168141593, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640980, Length=340, Percent_Identity=32.3529411764706, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI45549126, Length=340, Percent_Identity=32.3529411764706, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24646155, Length=314, Percent_Identity=27.3885350318471, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24646159, Length=237, Percent_Identity=29.1139240506329, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 36496; Mature: 36496

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYRRLGRSGLQISELSLGSWVTYGNQVDQRVARECLAAARDAGVNFFDNAEVYAGGKSE
CCHHHHCCCCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHH
EIMGQALKSLDWPRVSYIVSTKFFWGLAEAPNQYHTLNRKYLLNAIDGSLRRLQLDYVDL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHCCHHHHEEECCEEE
VYCHRPDPNTPIEETVWAMSDMIVRGKALYWGTSEWSADEIRAACEIAERHHLHKPVVEQ
EEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHCC
PQYNLFHRTRVEQEYARLYDDYGLGLTTWSPLASGLLTGKYRNGVPPGSRAQLQGYDWMR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
DRLTNQAANDIVERLGTIAAVLGCSTAQLAIAWVLANPRVSSVITGASRIEQIRDNMRAL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
DVAEKLTPDVKQRIEEVVGDAYE
HHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHYRRLGRSGLQISELSLGSWVTYGNQVDQRVARECLAAARDAGVNFFDNAEVYAGGKSE
CCHHHHCCCCCEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHH
EIMGQALKSLDWPRVSYIVSTKFFWGLAEAPNQYHTLNRKYLLNAIDGSLRRLQLDYVDL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHCCHHHHEEECCEEE
VYCHRPDPNTPIEETVWAMSDMIVRGKALYWGTSEWSADEIRAACEIAERHHLHKPVVEQ
EEEECCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHCC
PQYNLFHRTRVEQEYARLYDDYGLGLTTWSPLASGLLTGKYRNGVPPGSRAQLQGYDWMR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
DRLTNQAANDIVERLGTIAAVLGCSTAQLAIAWVLANPRVSSVITGASRIEQIRDNMRAL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
DVAEKLTPDVKQRIEEVVGDAYE
HHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]