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The map label for this gene is exbB [H]

Identifier: 78066997

GI number: 78066997

Start: 2622574

End: 2623305

Strand: Direct

Name: exbB [H]

Synonym: Bcep18194_A5528

Alternate gene names: 78066997

Gene position: 2622574-2623305 (Clockwise)

Preceding gene: 78066996

Following gene: 78066998

Centisome position: 70.99

GC content: 65.3

Gene sequence:

>732_bases
ATGCAAAGCTACGGTATCGCGCACGTCTGGGCGCAAGGTGATTTCGTCACGCGCGCCATCGCGATCACGCTGCTCGTGAT
GTCGGTCCTGTCGTGGATCGTGATCGTCATCAAGGGCTGGAACGTGATCCGCCTGAACCGCCTGACGAAGAACGCCGAAC
AGGCATTCTGGCATTCGGACGATTTCGACGACGGCATCAAGAAGCTCGGGCTCGCCGCATCGACGCCGAACGACAACCCG
TTCCTCGCGCTCGCGCTGTCGGGCAAGGAAGCCGCCGATCACCACCATCAGACTCAGCCGCACCTGCACGACCGCATGGA
CGTGTCGGACTGGGTCACGCGCTGCCTGAAGGACACGATGGACGAAGGCATCTCGCGCATGCAGAGCGGCCTCGCGATCC
TCGCGTCGATCGGCAGCACGGCGCCGTTCGTCGGCCTGTTCGGTACGGTCTGGGGGATCTACCACGCACTGCTCGCGATC
GGCGCATCCGGCCAGACGTCGATCGACCAGGTCGCGGGCCCGGTCGGCGAATCGCTGATCATGACCGCGTTCGGCCTGTT
CGTCGCGATCCCGGCCGTGCTCGGCTACAACGCACTCACCCGCGCGAACAAGGGTATCGTCAGCAAGCTGCGTCGCTTCG
CACACGGTCTGCATGCGTACTTCGTGACGGGCGCGAGCCTTGCCTCGTCGTCGACGCGCGACGGCCTGCGTCTCGCGACG
CGCGCCAGCTGA

Upstream 100 bases:

>100_bases
CGAGAACGGCCAGGCGATCCGCGCCGCCCATACGCTGCCCTTCAACTTCACGCTTGACGACTAACCCGTCATATTCGGTA
GATTCAAAGGAAATAAGAAA

Downstream 100 bases:

>100_bases
GACGGGGTGAACCATGGCAATGAACACCGGTTTCAGCGACGATGACGACGATGCAGTGATGAGCGAGATCAACATGACGC
CGCTCGTCGACGTCATGCTC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MQSYGIAHVWAQGDFVTRAIAITLLVMSVLSWIVIVIKGWNVIRLNRLTKNAEQAFWHSDDFDDGIKKLGLAASTPNDNP
FLALALSGKEAADHHHQTQPHLHDRMDVSDWVTRCLKDTMDEGISRMQSGLAILASIGSTAPFVGLFGTVWGIYHALLAI
GASGQTSIDQVAGPVGESLIMTAFGLFVAIPAVLGYNALTRANKGIVSKLRRFAHGLHAYFVTGASLASSSTRDGLRLAT
RAS

Sequences:

>Translated_243_residues
MQSYGIAHVWAQGDFVTRAIAITLLVMSVLSWIVIVIKGWNVIRLNRLTKNAEQAFWHSDDFDDGIKKLGLAASTPNDNP
FLALALSGKEAADHHHQTQPHLHDRMDVSDWVTRCLKDTMDEGISRMQSGLAILASIGSTAPFVGLFGTVWGIYHALLAI
GASGQTSIDQVAGPVGESLIMTAFGLFVAIPAVLGYNALTRANKGIVSKLRRFAHGLHAYFVTGASLASSSTRDGLRLAT
RAS
>Mature_243_residues
MQSYGIAHVWAQGDFVTRAIAITLLVMSVLSWIVIVIKGWNVIRLNRLTKNAEQAFWHSDDFDDGIKKLGLAASTPNDNP
FLALALSGKEAADHHHQTQPHLHDRMDVSDWVTRCLKDTMDEGISRMQSGLAILASIGSTAPFVGLFGTVWGIYHALLAI
GASGQTSIDQVAGPVGESLIMTAFGLFVAIPAVLGYNALTRANKGIVSKLRRFAHGLHAYFVTGASLASSSTRDGLRLAT
RAS

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=215, Percent_Identity=31.1627906976744, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1789381, Length=202, Percent_Identity=28.2178217821782, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26152; Mature: 26152

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSYGIAHVWAQGDFVTRAIAITLLVMSVLSWIVIVIKGWNVIRLNRLTKNAEQAFWHSD
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCC
DFDDGIKKLGLAASTPNDNPFLALALSGKEAADHHHQTQPHLHDRMDVSDWVTRCLKDTM
CHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHH
DEGISRMQSGLAILASIGSTAPFVGLFGTVWGIYHALLAIGASGQTSIDQVAGPVGESLI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHH
MTAFGLFVAIPAVLGYNALTRANKGIVSKLRRFAHGLHAYFVTGASLASSSTRDGLRLAT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHC
RAS
CCC
>Mature Secondary Structure
MQSYGIAHVWAQGDFVTRAIAITLLVMSVLSWIVIVIKGWNVIRLNRLTKNAEQAFWHSD
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCC
DFDDGIKKLGLAASTPNDNPFLALALSGKEAADHHHQTQPHLHDRMDVSDWVTRCLKDTM
CHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHH
DEGISRMQSGLAILASIGSTAPFVGLFGTVWGIYHALLAIGASGQTSIDQVAGPVGESLI
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHH
MTAFGLFVAIPAVLGYNALTRANKGIVSKLRRFAHGLHAYFVTGASLASSSTRDGLRLAT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHC
RAS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]