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The map label for this gene is ttuB [H]

Identifier: 78066967

GI number: 78066967

Start: 2586738

End: 2588105

Strand: Direct

Name: ttuB [H]

Synonym: Bcep18194_A5498

Alternate gene names: 78066967

Gene position: 2586738-2588105 (Clockwise)

Preceding gene: 78066966

Following gene: 78066968

Centisome position: 70.02

GC content: 67.32

Gene sequence:

>1368_bases
TTGAACCCGCCCTCGCCCGCTCTGCCCGGACGCGACCCGCTCGCGTCCGCCGTCTCGAAAGTGAAGTGGCACGTGCTGCC
GCTCGTGCTGATCATGTTCATCGCGAACTACATCGACCGCGTGAACGTCGGCTTCGTCGATCGTCACCTCGAAGCGTCGA
TCGGCATCGGCGCGGCCGCGTACGGGCTCGGCGCCGGGCTGTTCTTCGTCGGCTACGCGCTGTTCGAAGTGCCGTCGAAC
CTGCTGATGCAGCGCTACGGCGCACGCGTGTGGCTCGCCCGGATCATGGCGACGTGGGGCATCGTCGCGGCCGCGATGGC
GTTCGTGTGGAACGACACGTCGTTCTACACGCTGCGCTTCCTGCTCGGCGTGGCCGAGGCCGGCTTCTTCCCCGGCGTCG
TGCTGTACCTGTCGCAATGGCTGCCGCCGCAGGAGCGCGGCAAGGCGATGGCGATCTTCCTCGGCGGCTCCGCGTTCGCG
TCGGTACTGTCCGGGCCCGTTACGGGCGCGCTGCTGTCGATTCGCGGCTTCGGCCTCGAAGGCTGGCAATGGATGTTCCT
GATCGAAGGGCTGTTCTCGGTCGCGCTGTGCGGCGCGAGCTGGCTGCTGCTGAAATCGCATATCCGCGACGCGACGTGGC
TCACGGCCGAAGAACGCACGGCGCTCCAGAACGCGCTCGACGAGGAGCGCGCGACGCGCGACGTCCGCTCGAACGTGCCG
GTGCGCGCCACCGCGCTGCTGCGCGACCCGCAGATCATGCTGTTCTGCTTCCTGTATTTCTCGATCCAGCTGACGATCTA
CGCGGCCACGTTCTGGCTGCCGACGATCATCCGCAAGATGGGCGGCCTCACCGATTTCCAGGTCGGCCTGTACAACACGA
TTCCGTGGATGATCGCGATCGGCGCGATGTACGGCTTCGCGGTGCTGTCGTCGAAGTGGAAGCATCCGCAGCGCTGGCTC
TCAGTCGCGCTCGTGCTCGCCGCATGCGGGCTGTTCGCGTCGACGTCGCACGATCCGGTATGGTCGTTCGCGTCGATCTG
CTTCGCCGCGCTCGGCTTCAAGGCCGCGTCGTCGCTGTTCTGGCCGATCCCGCAGGGCTATCTCGACACGCGCGTGGCCG
CGGCCGTGATCGCGCTGATCAACTCGGTCGGCAACCTCGGCGGCTTCGTCGCGCCGACGGCGTTCGGCTATCTGAAGCAA
CATACGGGTTCGATCACGGGCGGGCTGTATGCGCTCGCGATCGCTTCGCTCGTCGCCGCGGTCGCCGCGCTGTTCGCGCG
CACGCACCGGCGTAGCGATCCGCCGCGCGGCCTGCCGGCCGACGAATCCTTCACGAACGCTTCGATGCTCCGCCATGCCG
AACACTGA

Upstream 100 bases:

>100_bases
TCAGGCGTACCATGTCATACGACGACATACTACACAGACTGCCACCCAGACGCTGACGCGAGCACCCGCCCCGTCCGCCG
CCGCCCGACCGGAGACACGC

Downstream 100 bases:

>100_bases
CCGCCCGACCGTCGTCGTCTCGAATGCCGCAGACGGCGATCTCTCCACCTTCTCGCTCGCGGCCGACGGCACGCTTGCGC
CGCTCGCCCGCTATCCCGCA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MNPPSPALPGRDPLASAVSKVKWHVLPLVLIMFIANYIDRVNVGFVDRHLEASIGIGAAAYGLGAGLFFVGYALFEVPSN
LLMQRYGARVWLARIMATWGIVAAAMAFVWNDTSFYTLRFLLGVAEAGFFPGVVLYLSQWLPPQERGKAMAIFLGGSAFA
SVLSGPVTGALLSIRGFGLEGWQWMFLIEGLFSVALCGASWLLLKSHIRDATWLTAEERTALQNALDEERATRDVRSNVP
VRATALLRDPQIMLFCFLYFSIQLTIYAATFWLPTIIRKMGGLTDFQVGLYNTIPWMIAIGAMYGFAVLSSKWKHPQRWL
SVALVLAACGLFASTSHDPVWSFASICFAALGFKAASSLFWPIPQGYLDTRVAAAVIALINSVGNLGGFVAPTAFGYLKQ
HTGSITGGLYALAIASLVAAVAALFARTHRRSDPPRGLPADESFTNASMLRHAEH

Sequences:

>Translated_455_residues
MNPPSPALPGRDPLASAVSKVKWHVLPLVLIMFIANYIDRVNVGFVDRHLEASIGIGAAAYGLGAGLFFVGYALFEVPSN
LLMQRYGARVWLARIMATWGIVAAAMAFVWNDTSFYTLRFLLGVAEAGFFPGVVLYLSQWLPPQERGKAMAIFLGGSAFA
SVLSGPVTGALLSIRGFGLEGWQWMFLIEGLFSVALCGASWLLLKSHIRDATWLTAEERTALQNALDEERATRDVRSNVP
VRATALLRDPQIMLFCFLYFSIQLTIYAATFWLPTIIRKMGGLTDFQVGLYNTIPWMIAIGAMYGFAVLSSKWKHPQRWL
SVALVLAACGLFASTSHDPVWSFASICFAALGFKAASSLFWPIPQGYLDTRVAAAVIALINSVGNLGGFVAPTAFGYLKQ
HTGSITGGLYALAIASLVAAVAALFARTHRRSDPPRGLPADESFTNASMLRHAEH
>Mature_455_residues
MNPPSPALPGRDPLASAVSKVKWHVLPLVLIMFIANYIDRVNVGFVDRHLEASIGIGAAAYGLGAGLFFVGYALFEVPSN
LLMQRYGARVWLARIMATWGIVAAAMAFVWNDTSFYTLRFLLGVAEAGFFPGVVLYLSQWLPPQERGKAMAIFLGGSAFA
SVLSGPVTGALLSIRGFGLEGWQWMFLIEGLFSVALCGASWLLLKSHIRDATWLTAEERTALQNALDEERATRDVRSNVP
VRATALLRDPQIMLFCFLYFSIQLTIYAATFWLPTIIRKMGGLTDFQVGLYNTIPWMIAIGAMYGFAVLSSKWKHPQRWL
SVALVLAACGLFASTSHDPVWSFASICFAALGFKAASSLFWPIPQGYLDTRVAAAVIALINSVGNLGGFVAPTAFGYLKQ
HTGSITGGLYALAIASLVAAVAALFARTHRRSDPPRGLPADESFTNASMLRHAEH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=415, Percent_Identity=23.6144578313253, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87082071, Length=419, Percent_Identity=33.4128878281623, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789515, Length=431, Percent_Identity=24.1299303944316, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789152, Length=438, Percent_Identity=25.1141552511416, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI2367379, Length=444, Percent_Identity=23.4234234234234, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI87082320, Length=451, Percent_Identity=21.7294900221729, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI2367193, Length=313, Percent_Identity=22.0447284345048, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=400, Percent_Identity=22.75, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25141318, Length=400, Percent_Identity=22.75, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI86561091, Length=274, Percent_Identity=22.6277372262774, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=249, Percent_Identity=24.4979919678715, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321698, Length=342, Percent_Identity=22.8070175438596, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=235, Percent_Identity=23.8297872340426, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324410, Length=151, Percent_Identity=26.4900662251656, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639764, Length=354, Percent_Identity=25.4237288135593, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641682, Length=378, Percent_Identity=25.6613756613757, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20130167, Length=374, Percent_Identity=22.7272727272727, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24654215, Length=378, Percent_Identity=23.015873015873, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922400, Length=378, Percent_Identity=23.015873015873, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49463; Mature: 49463

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPPSPALPGRDPLASAVSKVKWHVLPLVLIMFIANYIDRVNVGFVDRHLEASIGIGAAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
YGLGAGLFFVGYALFEVPSNLLMQRYGARVWLARIMATWGIVAAAMAFVWNDTSFYTLRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLGVAEAGFFPGVVLYLSQWLPPQERGKAMAIFLGGSAFASVLSGPVTGALLSIRGFGLE
HHHHHHCCCHHHHHHHHHHCCCHHHCCCEEEEEECCHHHHHHHCCCHHHHHHHHHCCCCC
GWQWMFLIEGLFSVALCGASWLLLKSHIRDATWLTAEERTALQNALDEERATRDVRSNVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
VRATALLRDPQIMLFCFLYFSIQLTIYAATFWLPTIIRKMGGLTDFQVGLYNTIPWMIAI
EEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
GAMYGFAVLSSKWKHPQRWLSVALVLAACGLFASTSHDPVWSFASICFAALGFKAASSLF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
WPIPQGYLDTRVAAAVIALINSVGNLGGFVAPTAFGYLKQHTGSITGGLYALAIASLVAA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VAALFARTHRRSDPPRGLPADESFTNASMLRHAEH
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNPPSPALPGRDPLASAVSKVKWHVLPLVLIMFIANYIDRVNVGFVDRHLEASIGIGAAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
YGLGAGLFFVGYALFEVPSNLLMQRYGARVWLARIMATWGIVAAAMAFVWNDTSFYTLRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLGVAEAGFFPGVVLYLSQWLPPQERGKAMAIFLGGSAFASVLSGPVTGALLSIRGFGLE
HHHHHHCCCHHHHHHHHHHCCCHHHCCCEEEEEECCHHHHHHHCCCHHHHHHHHHCCCCC
GWQWMFLIEGLFSVALCGASWLLLKSHIRDATWLTAEERTALQNALDEERATRDVRSNVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
VRATALLRDPQIMLFCFLYFSIQLTIYAATFWLPTIIRKMGGLTDFQVGLYNTIPWMIAI
EEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
GAMYGFAVLSSKWKHPQRWLSVALVLAACGLFASTSHDPVWSFASICFAALGFKAASSLF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
WPIPQGYLDTRVAAAVIALINSVGNLGGFVAPTAFGYLKQHTGSITGGLYALAIASLVAA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
VAALFARTHRRSDPPRGLPADESFTNASMLRHAEH
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]