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The map label for this gene is 78066697

Identifier: 78066697

GI number: 78066697

Start: 2284015

End: 2285013

Strand: Reverse

Name: 78066697

Synonym: Bcep18194_A5228

Alternate gene names: NA

Gene position: 2285013-2284015 (Counterclockwise)

Preceding gene: 78066698

Following gene: 78066694

Centisome position: 61.86

GC content: 71.57

Gene sequence:

>999_bases
ATGAACGACACGAATTCAGGGTCGGTGCGCGCGGCGGTGGTCGGGGTCGGCGCGATCGGCGGGTTGCTCGCGGCCGCGTT
GTCGCGGGCCGGCATGACCGTGAGCGCGTATGCGCGCGGCGCGACGCTCGACGCGTTGAACACGCACGGCGTGCGTGTAA
TCGACGAGGCGGGCGTCACATCGTCGGTTCCGGTGCGGGCGAGCGACGATGCGGCCGCGCTCGGCGTGCAGGACTACGTG
GTGATCGCGCTGAAGGCGCAGGCGCTGCCGGCGCTGGCCGCGCGCATCGCGCCGCTGGTCGGGCCGGATACCGTGATCGT
CGCGGCGATGAACGGGCTGCCGTGGTGGTTCACGCACGGGCTCGAAGGGGCGCTGGACGGCGTGCCGCTCGATGCGGTCG
ATCCGGCCGGCGCGGTGTCGGCGGCATTGCCGCCCGCGCAGGCGATCGGTTGCGTCGTGCACCTGTCGTCGAGCACCGAC
GCGCCGGGCATCGTGCGCCGCGGGCGCGGCAACCGGCTGATCGTCGGTGCGCCCGATGCGCGGCTCGATGTTGCCACGGC
GCGCTTCGCCGCGGCGCTGGCGGCGGGTGGTTTCGATGTCGAGTCGACGCCTGCGGTCCGGACCGAGATCTGGACGAAGC
TGTGGGGCAACATGAACATGAATCCGCTGAGCGCGCTGACGGGGTCGACGGCCGAGCAGCTGCTCGACGATCCGTTCACG
CAGGATCTCGCGCTGCGGATGATGGAGGAGGCGGCCGCGATCGGCGCGAAGCTCGGCCTGTCGACGGGGATGAGCGGGCC
CGAGCGGATCGCGGTCACGCGCAAGCTCGGCGCGTTCAAGACGTCGATGCTGCAGGATTTCGAAGCGGGGCGCGCGCTCG
AGATCGGGCCGATCCTCGGCGTGTTTCCCGAACTCGGGCGCAAGCTCGGCGTGCCGACCCCGTATTGCGACGCGGTGCTC
GGGCTGCTCCGGCAGCGCGCGGCGAACAGCGGGTTATAA

Upstream 100 bases:

>100_bases
AGTCGCACGACCGCCGCGCGTTGCACGCGGTCGCGTGAATGGTTGTGCCCGCAACCATTGAGCGTTATGCTCGTCAGCTC
CCAGGAGACGGAATTCCATC

Downstream 100 bases:

>100_bases
GCACGGGCGGGGCCGCTGCATGCGCGACGCCGGTGAGGCGAAGCGCTGCGATCCGCTTTCAACGCGTAGCGCCGTATGAC
GCAAAGCGGGCCGCCCGCGT

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNDTNSGSVRAAVVGVGAIGGLLAAALSRAGMTVSAYARGATLDALNTHGVRVIDEAGVTSSVPVRASDDAAALGVQDYV
VIALKAQALPALAARIAPLVGPDTVIVAAMNGLPWWFTHGLEGALDGVPLDAVDPAGAVSAALPPAQAIGCVVHLSSSTD
APGIVRRGRGNRLIVGAPDARLDVATARFAAALAAGGFDVESTPAVRTEIWTKLWGNMNMNPLSALTGSTAEQLLDDPFT
QDLALRMMEEAAAIGAKLGLSTGMSGPERIAVTRKLGAFKTSMLQDFEAGRALEIGPILGVFPELGRKLGVPTPYCDAVL
GLLRQRAANSGL

Sequences:

>Translated_332_residues
MNDTNSGSVRAAVVGVGAIGGLLAAALSRAGMTVSAYARGATLDALNTHGVRVIDEAGVTSSVPVRASDDAAALGVQDYV
VIALKAQALPALAARIAPLVGPDTVIVAAMNGLPWWFTHGLEGALDGVPLDAVDPAGAVSAALPPAQAIGCVVHLSSSTD
APGIVRRGRGNRLIVGAPDARLDVATARFAAALAAGGFDVESTPAVRTEIWTKLWGNMNMNPLSALTGSTAEQLLDDPFT
QDLALRMMEEAAAIGAKLGLSTGMSGPERIAVTRKLGAFKTSMLQDFEAGRALEIGPILGVFPELGRKLGVPTPYCDAVL
GLLRQRAANSGL
>Mature_332_residues
MNDTNSGSVRAAVVGVGAIGGLLAAALSRAGMTVSAYARGATLDALNTHGVRVIDEAGVTSSVPVRASDDAAALGVQDYV
VIALKAQALPALAARIAPLVGPDTVIVAAMNGLPWWFTHGLEGALDGVPLDAVDPAGAVSAALPPAQAIGCVVHLSSSTD
APGIVRRGRGNRLIVGAPDARLDVATARFAAALAAGGFDVESTPAVRTEIWTKLWGNMNMNPLSALTGSTAEQLLDDPFT
QDLALRMMEEAAAIGAKLGLSTGMSGPERIAVTRKLGAFKTSMLQDFEAGRALEIGPILGVFPELGRKLGVPTPYCDAVL
GLLRQRAANSGL

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33817; Mature: 33817

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTNSGSVRAAVVGVGAIGGLLAAALSRAGMTVSAYARGATLDALNTHGVRVIDEAGVT
CCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCEEEHHHCCCEEECCCCCCEEEEECCCCC
SSVPVRASDDAAALGVQDYVVIALKAQALPALAARIAPLVGPDTVIVAAMNGLPWWFTHG
CCCCCCCCCCHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCC
LEGALDGVPLDAVDPAGAVSAALPPAQAIGCVVHLSSSTDAPGIVRRGRGNRLIVGAPDA
CCHHCCCCCCCCCCCCCCHHHCCCCHHHEEEEEEECCCCCCCCCEECCCCCEEEEECCCC
RLDVATARFAAALAAGGFDVESTPAVRTEIWTKLWGNMNMNPLSALTGSTAEQLLDDPFT
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCCH
QDLALRMMEEAAAIGAKLGLSTGMSGPERIAVTRKLGAFKTSMLQDFEAGRALEIGPILG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHCCCEEEECHHHH
VFPELGRKLGVPTPYCDAVLGLLRQRAANSGL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDTNSGSVRAAVVGVGAIGGLLAAALSRAGMTVSAYARGATLDALNTHGVRVIDEAGVT
CCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCEEEHHHCCCEEECCCCCCEEEEECCCCC
SSVPVRASDDAAALGVQDYVVIALKAQALPALAARIAPLVGPDTVIVAAMNGLPWWFTHG
CCCCCCCCCCHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHCC
LEGALDGVPLDAVDPAGAVSAALPPAQAIGCVVHLSSSTDAPGIVRRGRGNRLIVGAPDA
CCHHCCCCCCCCCCCCCCHHHCCCCHHHEEEEEEECCCCCCCCCEECCCCCEEEEECCCC
RLDVATARFAAALAAGGFDVESTPAVRTEIWTKLWGNMNMNPLSALTGSTAEQLLDDPFT
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCCH
QDLALRMMEEAAAIGAKLGLSTGMSGPERIAVTRKLGAFKTSMLQDFEAGRALEIGPILG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHHCCCEEEECHHHH
VFPELGRKLGVPTPYCDAVLGLLRQRAANSGL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]