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The map label for this gene is hflC [H]

Identifier: 78066574

GI number: 78066574

Start: 2147132

End: 2148031

Strand: Reverse

Name: hflC [H]

Synonym: Bcep18194_A5105

Alternate gene names: 78066574

Gene position: 2148031-2147132 (Counterclockwise)

Preceding gene: 78066575

Following gene: 78066573

Centisome position: 58.15

GC content: 67.44

Gene sequence:

>900_bases
ATGAACCGAATCATTGCGCTCGTCGTCGCAATCGTGATCGTTGCCTTCGCGGCATCGTCGACAGTCCTTACCGTCGATCC
GCGCCATGCGGCCGTGCTGTCGGGGCGCGATGGCGCGCAGCCCGAGCTGGCAGGCCCCGGCATCCATTTCAAATTGCCGC
CGCCGCTGCAGACGGCCACGCTGATCGACACGCGCCTGCAATCGCTCGAGTCGTCGGATCCGCTGCAACTGGCAACGGAA
GACAAGCATGACCTGCTCGTCGCCTACGCGGTGAAGTACCGGATCAGCGATCCGATGAAGTACTTCACGACGACGGGGGG
CGACCCGTCGGCAGCCGGCGACCGTCTGGCCGGCGCGCTGAAGAGCGCACTCGGCGACGCGCTTGGCAAGCGCGCGCTCG
ACGATGCGCTCGGCGGCCAGCGTGCGATCGCCGATGCGGCGCGCGACGAAGTGAAGGCGAAGGCGTCCGGCTTCGGCGTC
GACGTGGTCGATGTCCAGCTGACGCGTGTCGACTTGCCGGCCGCGCAGACCGACGCCGTCTATCAGCGGATGATCGGCGC
GCTGCGCGATCAGGCGGCGCAGGTGCGTGCGCAAGGCGCGGCCGACGTCGAGCAGATCAAGGCGGACGCCGAACGCGAAC
AGCAGGCCGTGCTCGCGAACGCGTACAAGTCCGCGCAGACGATCAAGGGCGAGGGCGACGCGAAGGCTGCCACGATTGCC
GCCGACGCATTCGGCCGCGACCCGCAGTTCTACCAGTTCTACGCGAGCCTGCAGGCTTACCGAAACACGTTCAAGCGCAA
CGACATCATCGTCGTCGATCCCGACAGCGAGTTCTTCCGCTTCATGCGCAGCCCGACGGGCGGTGCCGCACCGGCGGCGC
CTGCTCCCCGCAAACACTGA

Upstream 100 bases:

>100_bases
GTCGGCCGTGGCGGCGTCGGGCACCGACGTGCTGCGATCGCGCGAAGCGTTTCGCAGCCGGTCGCGCGAAGACGATCTGA
AGTAACGGGGAGCGCAGAAC

Downstream 100 bases:

>100_bases
CCTTGGGGCGCCGCGTCGAGCGGCGCCGTCGCTCGCATGGACCTGGCTGGCTCGTTGTTGCTCGCAGTAGCGCTGATGCT
GATCATCGAGGGGGCGTTCC

Product: membrane protein, HflC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNRIIALVVAIVIVAFAASSTVLTVDPRHAAVLSGRDGAQPELAGPGIHFKLPPPLQTATLIDTRLQSLESSDPLQLATE
DKHDLLVAYAVKYRISDPMKYFTTTGGDPSAAGDRLAGALKSALGDALGKRALDDALGGQRAIADAARDEVKAKASGFGV
DVVDVQLTRVDLPAAQTDAVYQRMIGALRDQAAQVRAQGAADVEQIKADAEREQQAVLANAYKSAQTIKGEGDAKAATIA
ADAFGRDPQFYQFYASLQAYRNTFKRNDIIVVDPDSEFFRFMRSPTGGAAPAAPAPRKH

Sequences:

>Translated_299_residues
MNRIIALVVAIVIVAFAASSTVLTVDPRHAAVLSGRDGAQPELAGPGIHFKLPPPLQTATLIDTRLQSLESSDPLQLATE
DKHDLLVAYAVKYRISDPMKYFTTTGGDPSAAGDRLAGALKSALGDALGKRALDDALGGQRAIADAARDEVKAKASGFGV
DVVDVQLTRVDLPAAQTDAVYQRMIGALRDQAAQVRAQGAADVEQIKADAEREQQAVLANAYKSAQTIKGEGDAKAATIA
ADAFGRDPQFYQFYASLQAYRNTFKRNDIIVVDPDSEFFRFMRSPTGGAAPAAPAPRKH
>Mature_299_residues
MNRIIALVVAIVIVAFAASSTVLTVDPRHAAVLSGRDGAQPELAGPGIHFKLPPPLQTATLIDTRLQSLESSDPLQLATE
DKHDLLVAYAVKYRISDPMKYFTTTGGDPSAAGDRLAGALKSALGDALGKRALDDALGGQRAIADAARDEVKAKASGFGV
DVVDVQLTRVDLPAAQTDAVYQRMIGALRDQAAQVRAQGAADVEQIKADAEREQQAVLANAYKSAQTIKGEGDAKAATIA
ADAFGRDPQFYQFYASLQAYRNTFKRNDIIVVDPDSEFFRFMRSPTGGAAPAAPAPRKH

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=292, Percent_Identity=34.2465753424658, Blast_Score=157, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 31745; Mature: 31745

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIIALVVAIVIVAFAASSTVLTVDPRHAAVLSGRDGAQPELAGPGIHFKLPPPLQTAT
CHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCCCCCEEEECCCCCCHHH
LIDTRLQSLESSDPLQLATEDKHDLLVAYAVKYRISDPMKYFTTTGGDPSAAGDRLAGAL
HHHHHHHHHCCCCCCEEECCCCCCEEEEHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHH
KSALGDALGKRALDDALGGQRAIADAARDEVKAKASGFGVDVVDVQLTRVDLPAAQTDAV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHH
YQRMIGALRDQAAQVRAQGAADVEQIKADAEREQQAVLANAYKSAQTIKGEGDAKAATIA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEE
ADAFGRDPQFYQFYASLQAYRNTFKRNDIIVVDPDSEFFRFMRSPTGGAAPAAPAPRKH
HHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRIIALVVAIVIVAFAASSTVLTVDPRHAAVLSGRDGAQPELAGPGIHFKLPPPLQTAT
CHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCCCCCCCCCCEEEECCCCCCHHH
LIDTRLQSLESSDPLQLATEDKHDLLVAYAVKYRISDPMKYFTTTGGDPSAAGDRLAGAL
HHHHHHHHHCCCCCCEEECCCCCCEEEEHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHH
KSALGDALGKRALDDALGGQRAIADAARDEVKAKASGFGVDVVDVQLTRVDLPAAQTDAV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHH
YQRMIGALRDQAAQVRAQGAADVEQIKADAEREQQAVLANAYKSAQTIKGEGDAKAATIA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEE
ADAFGRDPQFYQFYASLQAYRNTFKRNDIIVVDPDSEFFRFMRSPTGGAAPAAPAPRKH
HHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]