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The map label for this gene is hflK [H]

Identifier: 78066575

GI number: 78066575

Start: 2148047

End: 2149351

Strand: Reverse

Name: hflK [H]

Synonym: Bcep18194_A5106

Alternate gene names: 78066575

Gene position: 2149351-2148047 (Counterclockwise)

Preceding gene: 78066576

Following gene: 78066574

Centisome position: 58.18

GC content: 67.36

Gene sequence:

>1305_bases
ATGCGCGCCTTGCTGTCGATCAACGATCCCCGCTGGGGACGCGGCGAAAGCAATGGCAAAGACGGATCTCGTCCCCGCCC
GAACGAATCGAAGCGTCCGCAAGGCGGCGACGGCGATGGTCCGCCCGATCTCGACGAGATGTGGCGCAACTTCAACCGGC
GGCTGAACGGCCTTTTCGGCGGCAAGGGCGGCAACGGTTTCCGTCCTGACAACGGGCGAGCCGCGCGAGTCGGTGTCGGC
ATCGTGATCGGCGTGCTGGTCGCGGTCTACGCGGGCAGCGGGCTGTTCGTCGTACAGGAAGGGCAGACGGGCGTCGTGCT
GCAGCTCGGCAAGCTGTCGGGCACGGTCGGCCAGGGTGTGCACTGGCGCGCGCCGTATCCGTTCGCGTCGCACGAGATCG
TCGATACGTCGCAGGTCCGCTCGATCGAGATCGGCCGCAACAACGTCGTGCGTCTCGCGAACGTGAAGGAAGCGGCGATG
CTGACGCGCGATGCCGACATCGTCGACGTGCGCTTCATCGTCCAGTACCGCATCCGCTCCGCGACCGATTACCTGTTCCG
CAGTGTCGATCCCGAGCGCAGCGTCTCGCAGGCCGCCCAGGCCGCGGTACGTGCGATCGTCGGCACGCGCAGCGCAGCCG
ACGTGCTGAACCAGGATCGCGACGCGCTGCGCGAGCAGCTTTCCGCCGCGATCCAGCGCGATCTCGATCGCTATCAGTCG
GGGCTCGAGGTGACGGCCGTCACGATGCAGAGCGTTGCGGCACCCGAGCAGACGCAGGCCGCGTACGGCGAAGTTGCGAA
GGCACGCGACGAGCGTGAAGCCGCGAAGCGCGCCGCGCAGGCATATGCAAACGACCTGCTGCCGAAGGCGCAGGGCGATG
CGGCGAAGCTCGTCGACGAAGCGAAGGCCTATGCCGATCGCGTGGTCACGGAAGCCGAGGGCGATGCCGACCGCTTCAAG
CAGGTCTATGCACAGTACTCGAAGGCGCCTGCGGTGATCCGCGAGCGGATGTATCTCGAGACGATGCAGGAAATCTATTC
GAACTCGACGAAGGTGTTCGTCGGCAACAAGGGCGGCAACAGCGTCGTGTATCTGCCGCTCGACAAGCTCGTCGAGCAGG
GGCGACAAAACGCCGCGGGGTCCACGGGCGCATCCACGCCCGATGCGGCGTCGGCACCGGCGGCTGTCGCGCCGGCCGCA
GCGGCACCCGCGAGTGCGGCGTCGGCCGTGGCGGCGTCGGGCACCGACGTGCTGCGATCGCGCGAAGCGTTTCGCAGCCG
GTCGCGCGAAGACGATCTGAAGTAA

Upstream 100 bases:

>100_bases
CCGAACACGGGCGCTAACCGGTCCCGGCCGGTTCGCCGGCGTCTAATCTGGTGAACAAACTCTGGTGAACGAATACAACG
AGCGGAGTACCTGGCGGCGG

Downstream 100 bases:

>100_bases
CGGGGAGCGCAGAACATGAACCGAATCATTGCGCTCGTCGTCGCAATCGTGATCGTTGCCTTCGCGGCATCGTCGACAGT
CCTTACCGTCGATCCGCGCC

Product: membrane protein, HflK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRALLSINDPRWGRGESNGKDGSRPRPNESKRPQGGDGDGPPDLDEMWRNFNRRLNGLFGGKGGNGFRPDNGRAARVGVG
IVIGVLVAVYAGSGLFVVQEGQTGVVLQLGKLSGTVGQGVHWRAPYPFASHEIVDTSQVRSIEIGRNNVVRLANVKEAAM
LTRDADIVDVRFIVQYRIRSATDYLFRSVDPERSVSQAAQAAVRAIVGTRSAADVLNQDRDALREQLSAAIQRDLDRYQS
GLEVTAVTMQSVAAPEQTQAAYGEVAKARDEREAAKRAAQAYANDLLPKAQGDAAKLVDEAKAYADRVVTEAEGDADRFK
QVYAQYSKAPAVIRERMYLETMQEIYSNSTKVFVGNKGGNSVVYLPLDKLVEQGRQNAAGSTGASTPDAASAPAAVAPAA
AAPASAASAVAASGTDVLRSREAFRSRSREDDLK

Sequences:

>Translated_434_residues
MRALLSINDPRWGRGESNGKDGSRPRPNESKRPQGGDGDGPPDLDEMWRNFNRRLNGLFGGKGGNGFRPDNGRAARVGVG
IVIGVLVAVYAGSGLFVVQEGQTGVVLQLGKLSGTVGQGVHWRAPYPFASHEIVDTSQVRSIEIGRNNVVRLANVKEAAM
LTRDADIVDVRFIVQYRIRSATDYLFRSVDPERSVSQAAQAAVRAIVGTRSAADVLNQDRDALREQLSAAIQRDLDRYQS
GLEVTAVTMQSVAAPEQTQAAYGEVAKARDEREAAKRAAQAYANDLLPKAQGDAAKLVDEAKAYADRVVTEAEGDADRFK
QVYAQYSKAPAVIRERMYLETMQEIYSNSTKVFVGNKGGNSVVYLPLDKLVEQGRQNAAGSTGASTPDAASAPAAVAPAA
AAPASAASAVAASGTDVLRSREAFRSRSREDDLK
>Mature_434_residues
MRALLSINDPRWGRGESNGKDGSRPRPNESKRPQGGDGDGPPDLDEMWRNFNRRLNGLFGGKGGNGFRPDNGRAARVGVG
IVIGVLVAVYAGSGLFVVQEGQTGVVLQLGKLSGTVGQGVHWRAPYPFASHEIVDTSQVRSIEIGRNNVVRLANVKEAAM
LTRDADIVDVRFIVQYRIRSATDYLFRSVDPERSVSQAAQAAVRAIVGTRSAADVLNQDRDALREQLSAAIQRDLDRYQS
GLEVTAVTMQSVAAPEQTQAAYGEVAKARDEREAAKRAAQAYANDLLPKAQGDAAKLVDEAKAYADRVVTEAEGDADRFK
QVYAQYSKAPAVIRERMYLETMQEIYSNSTKVFVGNKGGNSVVYLPLDKLVEQGRQNAAGSTGASTPDAASAPAAVAPAA
AAPASAASAVAASGTDVLRSREAFRSRSREDDLK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=387, Percent_Identity=32.2997416020672, Blast_Score=181, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 46478; Mature: 46478

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALLSINDPRWGRGESNGKDGSRPRPNESKRPQGGDGDGPPDLDEMWRNFNRRLNGLFG
CCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
GKGGNGFRPDNGRAARVGVGIVIGVLVAVYAGSGLFVVQEGQTGVVLQLGKLSGTVGQGV
CCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCE
HWRAPYPFASHEIVDTSQVRSIEIGRNNVVRLANVKEAAMLTRDADIVDVRFIVQYRIRS
EECCCCCCCCCCCCCCHHHEEEEECCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHH
ATDYLFRSVDPERSVSQAAQAAVRAIVGTRSAADVLNQDRDALREQLSAAIQRDLDRYQS
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHC
GLEVTAVTMQSVAAPEQTQAAYGEVAKARDEREAAKRAAQAYANDLLPKAQGDAAKLVDE
CCEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AKAYADRVVTEAEGDADRFKQVYAQYSKAPAVIRERMYLETMQEIYSNSTKVFVGNKGGN
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
SVVYLPLDKLVEQGRQNAAGSTGASTPDAASAPAAVAPAAAAPASAASAVAASGTDVLRS
EEEEECHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHCCHHHHHH
REAFRSRSREDDLK
HHHHHHCCCCCCCC
>Mature Secondary Structure
MRALLSINDPRWGRGESNGKDGSRPRPNESKRPQGGDGDGPPDLDEMWRNFNRRLNGLFG
CCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
GKGGNGFRPDNGRAARVGVGIVIGVLVAVYAGSGLFVVQEGQTGVVLQLGKLSGTVGQGV
CCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCE
HWRAPYPFASHEIVDTSQVRSIEIGRNNVVRLANVKEAAMLTRDADIVDVRFIVQYRIRS
EECCCCCCCCCCCCCCHHHEEEEECCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHH
ATDYLFRSVDPERSVSQAAQAAVRAIVGTRSAADVLNQDRDALREQLSAAIQRDLDRYQS
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHC
GLEVTAVTMQSVAAPEQTQAAYGEVAKARDEREAAKRAAQAYANDLLPKAQGDAAKLVDE
CCEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AKAYADRVVTEAEGDADRFKQVYAQYSKAPAVIRERMYLETMQEIYSNSTKVFVGNKGGN
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
SVVYLPLDKLVEQGRQNAAGSTGASTPDAASAPAAVAPAAAAPASAASAVAASGTDVLRS
EEEEECHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHCCHHHHHH
REAFRSRSREDDLK
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]