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The map label for this gene is yjjL [H]

Identifier: 78065823

GI number: 78065823

Start: 1307621

End: 1308982

Strand: Reverse

Name: yjjL [H]

Synonym: Bcep18194_A4352

Alternate gene names: 78065823

Gene position: 1308982-1307621 (Counterclockwise)

Preceding gene: 78065824

Following gene: 78065822

Centisome position: 35.43

GC content: 68.28

Gene sequence:

>1362_bases
ATGTTCGACTCCAACCCCGACGTGCTCGCCCCCGTGGCGGCACAAAGCCCGCCATCGGAATCACCCGCCGGACCACTCGC
GTGGTTCGGTCTCGCGATTCTCGTGATCGTGGCGTTCTTCGCCTTCGTCGACCGTCAGATGCTGATCCTGCTGACCGAGC
CCATCCGCCACGATTTCGGGCTGACCGACACGCAGATCGGCCTGATGCAAGGCGCAGGCATCGCGCTATTCGCGGGCGTG
GCCTCGTTGCCGATCGGCTGGGTCGCCGATCGCGTGGATCGCCGTGTGGTGCTGGTCGCGTGTGTCCTCGTGTGGAGCGC
TGCCACCGCGATCTGCGGCGTAACCACCCACTTCTGGCAATTGTTCATCGCCACCGTCGGGCTGGGGATCGGCGAAGCCG
GGCTGGTGCCGGTGATCTACGGCCTGATTCCCGACCTCTTCCCCGCGCGCCAGCGCGTGCTCGCCAATGCGATCTTCGCG
CTCGCCAACCTGCTGGGCGCAGGGGCGGGAATGGCGCTCGGCGGCGCACTGATGCAGGGCATCGCGGCCGTGCACGGTGC
GTTGCCCGCCGGACTTGCCGATCTCGCGCCGTGGCGGCTCGCGTTTTTTGCCGTTGCCCTGCCGGCCCCCGTGCTGGCCG
TACTGGTTCTACTCATTCGACCCGGCAAGCACCGCGACACGAACGCGTCCGCCGCGCGTCACCGGACTGCCGCGCCGCTG
CCGTCCGCACCGGTCTACTTCCGGCGCGAAGCCATCATGATGCTCAAGTTCTTCGGTGCCATCGGACTGGTCAATCTGTC
GTTCGGCGGTGTCGCGACATGGATGCCGGTCGTGGCGGTGCGAACCTTCGGCGCGACGCCGGCCGAAGCCGGCGGCGGCA
TGGGTGTGGCAGCGATGGCCGGTGGTATCGCGGGTTGCGTGCTCAGCGGACTCGTGGCCGGCCGCATGCGAGCGCGCTTC
GGCGTGCTCGCGCCGCTGCGCGTCTGTGAATGCGGCGCGCTGGTCGCCGGAGGGCTGTCGTTCCTCTATCTGGCAGTGGG
CTCGCTGACGCCCGTCTACGCGCTCTTCGGCGCCCAGCTCGCCTGCATGGTCGCAGGCATGGTGCTGTTTCCCACCATCA
TGCAGAACATCTGCCCTGCCCACCTGCGCTCGCGCGTGGCGGCGATCGGCGCGCTGACGTCGATCGTCGTGCAGTCCGGC
AGCCCCGTGTTCATCGGCTTCATGTCGGATCGCCTGCACGCGTTCAGCGAGGGCTTGCTGTGGTCGATCGTCTGCGTGGC
GGCGTTCGGCTTCTTTGCCGCCTGCCTGCTGATGCGCGCGGCGGGCCGTGGTGTCCGCGAGGCAATCGAACGCTATGCGT
AA

Upstream 100 bases:

>100_bases
GATGGTCATGGCGTCCGCGCAGCGGCTCGGCGCGAACCGCATCGGGCTCGTGGGCAACGAGCAGTTCATGCAGTAACCGC
CTTCTCATCACGGAGCCCTC

Downstream 100 bases:

>100_bases
TTCCCTTCTTCCTCACTCTTCCATGTCACCCCGCACGCTCTCACTCTCGCTGCGTATCGAACGCTGGCCGTTGGCCGCTC
CGTTCCATATCACCGGCCAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MFDSNPDVLAPVAAQSPPSESPAGPLAWFGLAILVIVAFFAFVDRQMLILLTEPIRHDFGLTDTQIGLMQGAGIALFAGV
ASLPIGWVADRVDRRVVLVACVLVWSAATAICGVTTHFWQLFIATVGLGIGEAGLVPVIYGLIPDLFPARQRVLANAIFA
LANLLGAGAGMALGGALMQGIAAVHGALPAGLADLAPWRLAFFAVALPAPVLAVLVLLIRPGKHRDTNASAARHRTAAPL
PSAPVYFRREAIMMLKFFGAIGLVNLSFGGVATWMPVVAVRTFGATPAEAGGGMGVAAMAGGIAGCVLSGLVAGRMRARF
GVLAPLRVCECGALVAGGLSFLYLAVGSLTPVYALFGAQLACMVAGMVLFPTIMQNICPAHLRSRVAAIGALTSIVVQSG
SPVFIGFMSDRLHAFSEGLLWSIVCVAAFGFFAACLLMRAAGRGVREAIERYA

Sequences:

>Translated_453_residues
MFDSNPDVLAPVAAQSPPSESPAGPLAWFGLAILVIVAFFAFVDRQMLILLTEPIRHDFGLTDTQIGLMQGAGIALFAGV
ASLPIGWVADRVDRRVVLVACVLVWSAATAICGVTTHFWQLFIATVGLGIGEAGLVPVIYGLIPDLFPARQRVLANAIFA
LANLLGAGAGMALGGALMQGIAAVHGALPAGLADLAPWRLAFFAVALPAPVLAVLVLLIRPGKHRDTNASAARHRTAAPL
PSAPVYFRREAIMMLKFFGAIGLVNLSFGGVATWMPVVAVRTFGATPAEAGGGMGVAAMAGGIAGCVLSGLVAGRMRARF
GVLAPLRVCECGALVAGGLSFLYLAVGSLTPVYALFGAQLACMVAGMVLFPTIMQNICPAHLRSRVAAIGALTSIVVQSG
SPVFIGFMSDRLHAFSEGLLWSIVCVAAFGFFAACLLMRAAGRGVREAIERYA
>Mature_453_residues
MFDSNPDVLAPVAAQSPPSESPAGPLAWFGLAILVIVAFFAFVDRQMLILLTEPIRHDFGLTDTQIGLMQGAGIALFAGV
ASLPIGWVADRVDRRVVLVACVLVWSAATAICGVTTHFWQLFIATVGLGIGEAGLVPVIYGLIPDLFPARQRVLANAIFA
LANLLGAGAGMALGGALMQGIAAVHGALPAGLADLAPWRLAFFAVALPAPVLAVLVLLIRPGKHRDTNASAARHRTAAPL
PSAPVYFRREAIMMLKFFGAIGLVNLSFGGVATWMPVVAVRTFGATPAEAGGGMGVAAMAGGIAGCVLSGLVAGRMRARF
GVLAPLRVCECGALVAGGLSFLYLAVGSLTPVYALFGAQLACMVAGMVLFPTIMQNICPAHLRSRVAAIGALTSIVVQSG
SPVFIGFMSDRLHAFSEGLLWSIVCVAAFGFFAACLLMRAAGRGVREAIERYA

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=421, Percent_Identity=25.1781472684086, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI215490096, Length=409, Percent_Identity=25.9168704156479, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI14042968, Length=409, Percent_Identity=25.9168704156479, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI215490100, Length=394, Percent_Identity=25.3807106598985, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367379, Length=425, Percent_Identity=25.8823529411765, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24654037, Length=413, Percent_Identity=24.455205811138, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24654041, Length=413, Percent_Identity=24.455205811138, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24654039, Length=413, Percent_Identity=24.2130750605327, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17864456, Length=413, Percent_Identity=24.2130750605327, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46904; Mature: 46904

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSNPDVLAPVAAQSPPSESPAGPLAWFGLAILVIVAFFAFVDRQMLILLTEPIRHDFG
CCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
LTDTQIGLMQGAGIALFAGVASLPIGWVADRVDRRVVLVACVLVWSAATAICGVTTHFWQ
CCCHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFIATVGLGIGEAGLVPVIYGLIPDLFPARQRVLANAIFALANLLGAGAGMALGGALMQG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IAAVHGALPAGLADLAPWRLAFFAVALPAPVLAVLVLLIRPGKHRDTNASAARHRTAAPL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCC
PSAPVYFRREAIMMLKFFGAIGLVNLSFGGVATWMPVVAVRTFGATPAEAGGGMGVAAMA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
GGIAGCVLSGLVAGRMRARFGVLAPLRVCECGALVAGGLSFLYLAVGSLTPVYALFGAQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ACMVAGMVLFPTIMQNICPAHLRSRVAAIGALTSIVVQSGSPVFIGFMSDRLHAFSEGLL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
WSIVCVAAFGFFAACLLMRAAGRGVREAIERYA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MFDSNPDVLAPVAAQSPPSESPAGPLAWFGLAILVIVAFFAFVDRQMLILLTEPIRHDFG
CCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
LTDTQIGLMQGAGIALFAGVASLPIGWVADRVDRRVVLVACVLVWSAATAICGVTTHFWQ
CCCHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFIATVGLGIGEAGLVPVIYGLIPDLFPARQRVLANAIFALANLLGAGAGMALGGALMQG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IAAVHGALPAGLADLAPWRLAFFAVALPAPVLAVLVLLIRPGKHRDTNASAARHRTAAPL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCC
PSAPVYFRREAIMMLKFFGAIGLVNLSFGGVATWMPVVAVRTFGATPAEAGGGMGVAAMA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
GGIAGCVLSGLVAGRMRARFGVLAPLRVCECGALVAGGLSFLYLAVGSLTPVYALFGAQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ACMVAGMVLFPTIMQNICPAHLRSRVAAIGALTSIVVQSGSPVFIGFMSDRLHAFSEGLL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHH
WSIVCVAAFGFFAACLLMRAAGRGVREAIERYA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]