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The map label for this gene is aaeR [H]

Identifier: 78065735

GI number: 78065735

Start: 1196963

End: 1197880

Strand: Reverse

Name: aaeR [H]

Synonym: Bcep18194_A4263

Alternate gene names: 78065735

Gene position: 1197880-1196963 (Counterclockwise)

Preceding gene: 78065738

Following gene: 78065734

Centisome position: 32.43

GC content: 68.85

Gene sequence:

>918_bases
ATGAACGATAAAGCGCGGGATCTGAACGATCTCTATTACTTCGTGCAGGTCGTCGAACACGGCGGCTTCGCACCGGCCGG
GCGTGCGCTGGACATGCCGAAATCGAAGCTGAGTCGCCGCATCGCGCTGCTCGAGGCGCGGCTCGGGATGCGGCTGATCC
AGCGCTCGACGCGGCGCTTCACGGTTACCGACGTCGGCCAGACCTATTACGCGCATTGCCGCGCGATGCTCGTCGAAGCC
GATGCGGCCGACGAGGCGATCGCGCTGCTGCACGAGGAACCGCGCGGCATCGTGCGCGTCAGTTGCCCGATCGTACTGCT
CGATTCGCTGGTCGGCACGATGATCGCCGCGTTCATGGTTGCGTGCCCACGCGTCGAGATCCATCTGGAAGCGACCAACC
GGCGCGTCGACGTGGTTGGCGAAGGGATCGACGTCGCGATCCGCGTGCGCCCGCCGCCACTCGAAGACAGCGATCTCGCG
CTGCGCATGCTGGCCGAGCGCGGCCAATGCCTCGTCGCGAGCCCCTCGCTGCTGCGCGAGCACGGCGCACCGGCCGTTCC
CGCCGATCTCGCACGCCTGCCGAGTCTCGATCACGGCGCCCCGCAGTCCGCGCACGTGTGGCGACTGCGCGGGCCCGATG
GCGCTCACGCGGAAATTCATCACCAGCCGCGCTTCGTGACGGGCGGCATGCTCGCGCTGCGCGCGGCGGCCGTCGCGGGC
GTCGGCATCGTGCAATTGCCGACGATGATGGTGCGCGATGAGGTCGCGCGCGGCGAGCTGGTGACCGTACTGCCCGACTG
GGCGCCGCGCCGCGAGATCGTGCATGCGGTGTTCGCGTCGCGCCGGGGGCTGCTGCCCTCAGTACGCGCGCTGCTCGATT
TCCTGGCGGAGCGGTTTGCCGAACTCGAACCCGATTGA

Upstream 100 bases:

>100_bases
CGAATTGCGGCGAAACACGTGTTTCGCATCCTGGGTAGAAATATAGTGGTGGAACGATCGATCCGGTAGACTGCCAAAAT
CGCACTCAGCGTTCCATTTC

Downstream 100 bases:

>100_bases
GCGCGCCGCTTCACGCGTAACCGGGCGCTGCAAACCACGCACGCGTGCCGTAGACTGCGGTACGCGCATCGCGCATTCCA
CAACCCTGATCGTTTTCCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNDKARDLNDLYYFVQVVEHGGFAPAGRALDMPKSKLSRRIALLEARLGMRLIQRSTRRFTVTDVGQTYYAHCRAMLVEA
DAADEAIALLHEEPRGIVRVSCPIVLLDSLVGTMIAAFMVACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLEDSDLA
LRMLAERGQCLVASPSLLREHGAPAVPADLARLPSLDHGAPQSAHVWRLRGPDGAHAEIHHQPRFVTGGMLALRAAAVAG
VGIVQLPTMMVRDEVARGELVTVLPDWAPRREIVHAVFASRRGLLPSVRALLDFLAERFAELEPD

Sequences:

>Translated_305_residues
MNDKARDLNDLYYFVQVVEHGGFAPAGRALDMPKSKLSRRIALLEARLGMRLIQRSTRRFTVTDVGQTYYAHCRAMLVEA
DAADEAIALLHEEPRGIVRVSCPIVLLDSLVGTMIAAFMVACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLEDSDLA
LRMLAERGQCLVASPSLLREHGAPAVPADLARLPSLDHGAPQSAHVWRLRGPDGAHAEIHHQPRFVTGGMLALRAAAVAG
VGIVQLPTMMVRDEVARGELVTVLPDWAPRREIVHAVFASRRGLLPSVRALLDFLAERFAELEPD
>Mature_305_residues
MNDKARDLNDLYYFVQVVEHGGFAPAGRALDMPKSKLSRRIALLEARLGMRLIQRSTRRFTVTDVGQTYYAHCRAMLVEA
DAADEAIALLHEEPRGIVRVSCPIVLLDSLVGTMIAAFMVACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLEDSDLA
LRMLAERGQCLVASPSLLREHGAPAVPADLARLPSLDHGAPQSAHVWRLRGPDGAHAEIHHQPRFVTGGMLALRAAAVAG
VGIVQLPTMMVRDEVARGELVTVLPDWAPRREIVHAVFASRRGLLPSVRALLDFLAERFAELEPD

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=30.8474576271186, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=31.6151202749141, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI87081978, Length=305, Percent_Identity=32.1311475409836, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=30.3448275862069, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789440, Length=290, Percent_Identity=25.8620689655172, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=23.3898305084746, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787589, Length=282, Percent_Identity=25.886524822695, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789173, Length=263, Percent_Identity=26.9961977186312, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI157672245, Length=157, Percent_Identity=29.9363057324841, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33442; Mature: 33442

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKARDLNDLYYFVQVVEHGGFAPAGRALDMPKSKLSRRIALLEARLGMRLIQRSTRRF
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
TVTDVGQTYYAHCRAMLVEADAADEAIALLHEEPRGIVRVSCPIVLLDSLVGTMIAAFMV
EEEECHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHH
ACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLEDSDLALRMLAERGQCLVASPSLLRE
HCCCEEEEEEECCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECHHHHHH
HGAPAVPADLARLPSLDHGAPQSAHVWRLRGPDGAHAEIHHQPRFVTGGMLALRAAAVAG
CCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCEEHHHHHHHHHHHHHC
VGIVQLPTMMVRDEVARGELVTVLPDWAPRREIVHAVFASRRGLLPSVRALLDFLAERFA
CCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ELEPD
HCCCC
>Mature Secondary Structure
MNDKARDLNDLYYFVQVVEHGGFAPAGRALDMPKSKLSRRIALLEARLGMRLIQRSTRRF
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
TVTDVGQTYYAHCRAMLVEADAADEAIALLHEEPRGIVRVSCPIVLLDSLVGTMIAAFMV
EEEECHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHH
ACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLEDSDLALRMLAERGQCLVASPSLLRE
HCCCEEEEEEECCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECHHHHHH
HGAPAVPADLARLPSLDHGAPQSAHVWRLRGPDGAHAEIHHQPRFVTGGMLALRAAAVAG
CCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCEEHHHHHHHHHHHHHC
VGIVQLPTMMVRDEVARGELVTVLPDWAPRREIVHAVFASRRGLLPSVRALLDFLAERFA
CCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ELEPD
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]