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The map label for this gene is add [H]

Identifier: 78065603

GI number: 78065603

Start: 1061672

End: 1062697

Strand: Reverse

Name: add [H]

Synonym: Bcep18194_A4131

Alternate gene names: 78065603

Gene position: 1062697-1061672 (Counterclockwise)

Preceding gene: 78065604

Following gene: 78065602

Centisome position: 28.77

GC content: 64.91

Gene sequence:

>1026_bases
ATGACCCCGACATTCAAGGACAAGATTGCCCGCGCGCCGAAAGCGGAGCTGCACATCCATATCGAAGGCTCGCTCGAGCC
CGAACTGATTTTTGCGCTCGCACAGCGCAACGGCGTGAAGCTCGCGTACGACTCGATCGACGCGCTGCGCGCCGCGTACG
CATTCACCGACCTGCAATCGTTCCTCGACATCTATTACGCCGGTGCGAGCGTGCTGCTGACCGAGCAGGATTTCTACGAC
ATGACGGCCGCGTACTGCGAACGCGCACTCGCCGACAACGTCGTCCACACCGAGCTGTTCTTCGATCCGCAGACGCACAC
CGAACGTGGCGTGCCGATCGACACGGTCGTCGCGGGCATCGAGCGTGCACTCGCCGATGCCGAACAACGCGGGCTGTCGA
GCAAGCTGATCCTGTGCTTCCTGCGCCACCTGTCCGAAGAGGACGCGCTCGCGACGTTCGAATCCGCGCTGCCGCTGTTC
GAACGCTATCGCCATCGCCTGATCGGCGTGGGCCTCGACTCGTCCGAGCTGGGCCATCCGCCGACGAAGTTCGCCCGCGT
GTTCGAGAAGGCACGCGCGCTCGGGCTGAAGCTCGTCGCGCACGCGGGCGAGGAAGGCCCGCCCGCGTACATCTACGAAG
CGCTCGACGTGCTGAAGGTCGACCGGATCGACCACGGCGTGCGCAGCATCGAGGACGCGGCACTCGTCGAGCGCCTCGCG
AAAACGCGCACGGCGCTCACCGTGTGCCCGCTGTCGAACCTGAAGCTTTGCGTGTTCGACGACATGGCGAAGCACACGCT
GAAGGCGCTGCTCGATCGCGGCGTCGCGGTGACGATCAACTCCGACGATCCGGCTTATTTCGGCGGCTACGTCAACGAAA
ACTACTTCGCGACGGCCGAAGGGCTGCAACTCACGGATGCCGAAGTCCATGCGGTGATCCGCAACGGCTTCGAGGCGTCG
TTCATCGAACCGGCGCAGCGCGACGCACTGTACGCGCGCCTCGACGCGTACTGGCAGGCCGCGTGA

Upstream 100 bases:

>100_bases
CGCGATCTCGGTGGCGGCGCAATTGCTGCAGGCCGTCGAGGCAAACGCGAATGCGTCCGCACAGGCTTCCCCTACCTACT
GACCGACCAAGAACGACGCC

Downstream 100 bases:

>100_bases
CGGCCGGCATCGAGGAACGCTGACAGATGAAACACGGCAACGGCATCCGCTTCGCGACCACCGGCCCGGCCTTGCGCCGG
GACGACCGCGCGCGTGAGCG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTPTFKDKIARAPKAELHIHIEGSLEPELIFALAQRNGVKLAYDSIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYD
MTAAYCERALADNVVHTELFFDPQTHTERGVPIDTVVAGIERALADAEQRGLSSKLILCFLRHLSEEDALATFESALPLF
ERYRHRLIGVGLDSSELGHPPTKFARVFEKARALGLKLVAHAGEEGPPAYIYEALDVLKVDRIDHGVRSIEDAALVERLA
KTRTALTVCPLSNLKLCVFDDMAKHTLKALLDRGVAVTINSDDPAYFGGYVNENYFATAEGLQLTDAEVHAVIRNGFEAS
FIEPAQRDALYARLDAYWQAA

Sequences:

>Translated_341_residues
MTPTFKDKIARAPKAELHIHIEGSLEPELIFALAQRNGVKLAYDSIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYD
MTAAYCERALADNVVHTELFFDPQTHTERGVPIDTVVAGIERALADAEQRGLSSKLILCFLRHLSEEDALATFESALPLF
ERYRHRLIGVGLDSSELGHPPTKFARVFEKARALGLKLVAHAGEEGPPAYIYEALDVLKVDRIDHGVRSIEDAALVERLA
KTRTALTVCPLSNLKLCVFDDMAKHTLKALLDRGVAVTINSDDPAYFGGYVNENYFATAEGLQLTDAEVHAVIRNGFEAS
FIEPAQRDALYARLDAYWQAA
>Mature_340_residues
TPTFKDKIARAPKAELHIHIEGSLEPELIFALAQRNGVKLAYDSIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYDM
TAAYCERALADNVVHTELFFDPQTHTERGVPIDTVVAGIERALADAEQRGLSSKLILCFLRHLSEEDALATFESALPLFE
RYRHRLIGVGLDSSELGHPPTKFARVFEKARALGLKLVAHAGEEGPPAYIYEALDVLKVDRIDHGVRSIEDAALVERLAK
TRTALTVCPLSNLKLCVFDDMAKHTLKALLDRGVAVTINSDDPAYFGGYVNENYFATAEGLQLTDAEVHAVIRNGFEASF
IEPAQRDALYARLDAYWQAA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=371, Percent_Identity=25.0673854447439, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1787910, Length=334, Percent_Identity=28.4431137724551, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32565969, Length=344, Percent_Identity=21.5116279069767, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17538512, Length=344, Percent_Identity=21.5116279069767, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324188, Length=331, Percent_Identity=43.8066465256798, Blast_Score=281, Evalue=9e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37766; Mature: 37635

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTFKDKIARAPKAELHIHIEGSLEPELIFALAQRNGVKLAYDSIDALRAAYAFTDLQS
CCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH
FLDIYYAGASVLLTEQDFYDMTAAYCERALADNVVHTELFFDPQTHTERGVPIDTVVAGI
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHH
ERALADAEQRGLSSKLILCFLRHLSEEDALATFESALPLFERYRHRLIGVGLDSSELGHP
HHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCC
PTKFARVFEKARALGLKLVAHAGEEGPPAYIYEALDVLKVDRIDHGVRSIEDAALVERLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTRTALTVCPLSNLKLCVFDDMAKHTLKALLDRGVAVTINSDDPAYFGGYVNENYFATAE
HHHHEEEEECCCCCEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEECC
GLQLTDAEVHAVIRNGFEASFIEPAQRDALYARLDAYWQAA
CCEECHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPTFKDKIARAPKAELHIHIEGSLEPELIFALAQRNGVKLAYDSIDALRAAYAFTDLQS
CCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHH
FLDIYYAGASVLLTEQDFYDMTAAYCERALADNVVHTELFFDPQTHTERGVPIDTVVAGI
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHH
ERALADAEQRGLSSKLILCFLRHLSEEDALATFESALPLFERYRHRLIGVGLDSSELGHP
HHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCC
PTKFARVFEKARALGLKLVAHAGEEGPPAYIYEALDVLKVDRIDHGVRSIEDAALVERLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTRTALTVCPLSNLKLCVFDDMAKHTLKALLDRGVAVTINSDDPAYFGGYVNENYFATAE
HHHHEEEEECCCCCEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEECC
GLQLTDAEVHAVIRNGFEASFIEPAQRDALYARLDAYWQAA
CCEECHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA