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The map label for this gene is cutS [H]

Identifier: 78065398

GI number: 78065398

Start: 839928

End: 841478

Strand: Direct

Name: cutS [H]

Synonym: Bcep18194_A3924

Alternate gene names: 78065398

Gene position: 839928-841478 (Clockwise)

Preceding gene: 78065396

Following gene: 78065399

Centisome position: 22.74

GC content: 69.31

Gene sequence:

>1551_bases
ATGAGTGAGCCGATCCGCTTCTACCATCGTCACGCGATCCGCGAAGTCAGCGGCGCGGACGTTACCCGCACCGTGCTGCA
ATACCTGCGCGAGGACGCGCATTGCACCGGCACCAAGGAAGGCTGCGCGGAAGGCGACTGCGGCGCGTGCACGGTCGTCG
TCGGCGAGCTGACCGATGCCGGCGCGGTCGAGTTCAAGGCCGTCAACGCATGCATCCAGTTCCTGCCGACGCTGGACGGC
AAGGCGCTGCTCACGGTCGAGGACCTGCGTCAGCCGGACGGCGCGCTGCATCCGGTGCAGCAGGCGATGGTCGACTGCCA
CGGTTCGCAATGCGGGTTCTGCACGCCCGGCTTCGTGATGTCGATGTGGGCGCTGTACGAGAAGCACGGCCACGAAGGTT
GCGGCAGCGCCGGCACGTGCGCGAAGGCGAAGGACGTGCCGACGCGCACCGAGATCGCCGATGCGCTGACCGGCAACCTG
TGCCGCTGCACCGGCTATCGCCCGATCGTCGATGCGGCCGTGCAGATGTTCGATGCGCCCGCACCGTCGGCGCCGGTCGA
CACCGCCGCGCTGGCTCGCACACTCGCGTCGCTCAAGCGCGACGATACGTTCGACTACACGACGATCAACGGCGCGCGCT
TCGCGGCGCCGCGCACGCTCGACGCACTGGCCGCGCTGAAGGTCGAGCGGCCCGACGCGCGCATTCTCGCGGGCAGCACC
GACATCGGCCTGTGGGTCACCAAGCAGATGCGCCGGCTCGACGACCTGATCTACGTCGGCCAGATCGCCGAACTGCAGCG
CCTCATGGAGCGCGGCGACTGGATCGAGATCGGCGCGGGCGTGACGGTCGAGAAGGCGTATGCGGCGCTGGCCGGCCAGT
ATCCGGAACTGACCGAGATGTGGAAGCGCTTCGCGTCGCTGCCGATCCGCAACGCGGGCACGATCGGCGGCAACGTCGCG
AACGGCTCGCCGATCGGCGATTCGATGCCGGGCCTGATCGCGCTCGGCGCGCGCGTGGTGCTGCGCGGCGGCGACACGGT
GCGCGAGCTGCCGCTCGAGGCACTGTACACGGGCTACCAGCAGAAGGACATGGCGCCGCACGAATTCGTCATCGGCCTGA
AGGTGCCGACCCGCACCGGCGCGCGCGAGAAGCTGCAGTTCCGCACGTACAAGCTGTCGAAGCGGTTCGACTCCGACATC
TCGGCCGTGTGCGCGGCGTTCGCGTTCATCGCGGACGGCGACACGATCCGCGAGCCGCGCATCGCGTTCGGCGGGATGGC
CGCGACGCCGAAGCGTGCAACGCACACGGAAGCCGTGCTCGACGGCGCGCAGTGGCACGAAGCCACCGCACAGGCCGCGA
TGCAGGCGCTCGAGCGCGACTACCAGCCGCTGTCCGACATGCGCGCGACGAGCACGTACCGCCTCGATACCGCGAAGAAC
CTGATGTACCGATTCTGGCTGGAGACGCGCCCGCACGACCCGCTGCCGCCGCAAGCCCTGAATGTGCGTGAAGTGGCCGC
CGAACTCGGCACCGACGCGGCGCGCGTCTGA

Upstream 100 bases:

>100_bases
TTGCGGAATTTGATGGTGATAGCGTGCAAACTGTCAGAAAAACGTCGGTCGAGCGCACTGCGCGGGCCGCCTTGCCCCCC
ATTTGAAGAACCATCGAGAC

Downstream 100 bases:

>100_bases
AGACGGAGAACACCGAACATGAACCAGCAAGCAGAACCGTTCCTGAGCACCCTCGACCCGCAAGCCGACGCGGCGCAGGT
CCACGTATCGCGCGCGCACG

Product: molybdopterin dehydrogenase, FAD-binding

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MSEPIRFYHRHAIREVSGADVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVVGELTDAGAVEFKAVNACIQFLPTLDG
KALLTVEDLRQPDGALHPVQQAMVDCHGSQCGFCTPGFVMSMWALYEKHGHEGCGSAGTCAKAKDVPTRTEIADALTGNL
CRCTGYRPIVDAAVQMFDAPAPSAPVDTAALARTLASLKRDDTFDYTTINGARFAAPRTLDALAALKVERPDARILAGST
DIGLWVTKQMRRLDDLIYVGQIAELQRLMERGDWIEIGAGVTVEKAYAALAGQYPELTEMWKRFASLPIRNAGTIGGNVA
NGSPIGDSMPGLIALGARVVLRGGDTVRELPLEALYTGYQQKDMAPHEFVIGLKVPTRTGAREKLQFRTYKLSKRFDSDI
SAVCAAFAFIADGDTIREPRIAFGGMAATPKRATHTEAVLDGAQWHEATAQAAMQALERDYQPLSDMRATSTYRLDTAKN
LMYRFWLETRPHDPLPPQALNVREVAAELGTDAARV

Sequences:

>Translated_516_residues
MSEPIRFYHRHAIREVSGADVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVVGELTDAGAVEFKAVNACIQFLPTLDG
KALLTVEDLRQPDGALHPVQQAMVDCHGSQCGFCTPGFVMSMWALYEKHGHEGCGSAGTCAKAKDVPTRTEIADALTGNL
CRCTGYRPIVDAAVQMFDAPAPSAPVDTAALARTLASLKRDDTFDYTTINGARFAAPRTLDALAALKVERPDARILAGST
DIGLWVTKQMRRLDDLIYVGQIAELQRLMERGDWIEIGAGVTVEKAYAALAGQYPELTEMWKRFASLPIRNAGTIGGNVA
NGSPIGDSMPGLIALGARVVLRGGDTVRELPLEALYTGYQQKDMAPHEFVIGLKVPTRTGAREKLQFRTYKLSKRFDSDI
SAVCAAFAFIADGDTIREPRIAFGGMAATPKRATHTEAVLDGAQWHEATAQAAMQALERDYQPLSDMRATSTYRLDTAKN
LMYRFWLETRPHDPLPPQALNVREVAAELGTDAARV
>Mature_515_residues
SEPIRFYHRHAIREVSGADVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVVGELTDAGAVEFKAVNACIQFLPTLDGK
ALLTVEDLRQPDGALHPVQQAMVDCHGSQCGFCTPGFVMSMWALYEKHGHEGCGSAGTCAKAKDVPTRTEIADALTGNLC
RCTGYRPIVDAAVQMFDAPAPSAPVDTAALARTLASLKRDDTFDYTTINGARFAAPRTLDALAALKVERPDARILAGSTD
IGLWVTKQMRRLDDLIYVGQIAELQRLMERGDWIEIGAGVTVEKAYAALAGQYPELTEMWKRFASLPIRNAGTIGGNVAN
GSPIGDSMPGLIALGARVVLRGGDTVRELPLEALYTGYQQKDMAPHEFVIGLKVPTRTGAREKLQFRTYKLSKRFDSDIS
AVCAAFAFIADGDTIREPRIAFGGMAATPKRATHTEAVLDGAQWHEATAQAAMQALERDYQPLSDMRATSTYRLDTAKNL
MYRFWLETRPHDPLPPQALNVREVAAELGTDAARV

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG4630

COG function: function code F; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=525, Percent_Identity=29.3333333333333, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI71773480, Length=104, Percent_Identity=46.1538461538462, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1789231, Length=290, Percent_Identity=26.8965517241379, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1786480, Length=155, Percent_Identity=38.0645161290323, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789232, Length=149, Percent_Identity=36.9127516778523, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17540638, Length=549, Percent_Identity=26.9581056466302, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17539860, Length=482, Percent_Identity=26.5560165975104, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=481, Percent_Identity=25.5717255717256, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17737937, Length=506, Percent_Identity=31.0276679841897, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24647197, Length=522, Percent_Identity=27.9693486590038, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24647199, Length=501, Percent_Identity=27.9441117764471, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24647201, Length=502, Percent_Identity=25.8964143426295, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24647193, Length=501, Percent_Identity=27.9441117764471, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24647195, Length=338, Percent_Identity=31.3609467455621, Blast_Score=143, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 55997; Mature: 55866

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00197 2FE2S_FER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPIRFYHRHAIREVSGADVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVVGELTDA
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCC
GAVEFKAVNACIQFLPTLDGKALLTVEDLRQPDGALHPVQQAMVDCHGSQCGFCTPGFVM
CCHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHH
SMWALYEKHGHEGCGSAGTCAKAKDVPTRTEIADALTGNLCRCTGYRPIVDAAVQMFDAP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCC
APSAPVDTAALARTLASLKRDDTFDYTTINGARFAAPRTLDALAALKVERPDARILAGST
CCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEECCC
DIGLWVTKQMRRLDDLIYVGQIAELQRLMERGDWIEIGAGVTVEKAYAALAGQYPELTEM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCHHHHHH
WKRFASLPIRNAGTIGGNVANGSPIGDSMPGLIALGARVVLRGGDTVRELPLEALYTGYQ
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCHHHHCCHHHHHCCCH
QKDMAPHEFVIGLKVPTRTGAREKLQFRTYKLSKRFDSDISAVCAAFAFIADGDTIREPR
HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
IAFGGMAATPKRATHTEAVLDGAQWHEATAQAAMQALERDYQPLSDMRATSTYRLDTAKN
HHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEECHHHHH
LMYRFWLETRPHDPLPPQALNVREVAAELGTDAARV
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCHHCCC
>Mature Secondary Structure 
SEPIRFYHRHAIREVSGADVTRTVLQYLREDAHCTGTKEGCAEGDCGACTVVVGELTDA
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCC
GAVEFKAVNACIQFLPTLDGKALLTVEDLRQPDGALHPVQQAMVDCHGSQCGFCTPGFVM
CCHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHH
SMWALYEKHGHEGCGSAGTCAKAKDVPTRTEIADALTGNLCRCTGYRPIVDAAVQMFDAP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCC
APSAPVDTAALARTLASLKRDDTFDYTTINGARFAAPRTLDALAALKVERPDARILAGST
CCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEECCC
DIGLWVTKQMRRLDDLIYVGQIAELQRLMERGDWIEIGAGVTVEKAYAALAGQYPELTEM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCHHHHHH
WKRFASLPIRNAGTIGGNVANGSPIGDSMPGLIALGARVVLRGGDTVRELPLEALYTGYQ
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCHHHHCCHHHHHCCCH
QKDMAPHEFVIGLKVPTRTGAREKLQFRTYKLSKRFDSDISAVCAAFAFIADGDTIREPR
HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
IAFGGMAATPKRATHTEAVLDGAQWHEATAQAAMQALERDYQPLSDMRATSTYRLDTAKN
HHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEECHHHHH
LMYRFWLETRPHDPLPPQALNVREVAAELGTDAARV
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]