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The map label for this gene is pntB [H]

Identifier: 78065264

GI number: 78065264

Start: 683449

End: 684903

Strand: Direct

Name: pntB [H]

Synonym: Bcep18194_A3788

Alternate gene names: 78065264

Gene position: 683449-684903 (Clockwise)

Preceding gene: 78065263

Following gene: 78065266

Centisome position: 18.5

GC content: 65.22

Gene sequence:

>1455_bases
ATGAGCATGAACGTCGTCACGCTGCTGTACCTCGTCGCATCGGTGTGCTTCATCCAGGCGCTGAAAGGCCTGTCGAACCC
GAAGAGCGCGCGGCGCGGCAACCTGTTCGGGATGGCCGGGATGGCCATCGCGATCCTCACGACGATCGCGCTGATCGTCA
AGCAGGCCGAGTGGCTCGGCGCGAACCTGCCGCTCGGCATCGCGCTGGTGCTCGGCGCGCTGATCGTCGGCGGCGGCGTG
GGGGCGTTCGTCGCCGCGCGCGTCGAGATGACGAAGATGCCGGAGCTCGTCGCGGCGATGCATTCGCTGATCGGTCTCGC
GGCCGTGTGCATCGCGTATGCGGTGGTGTCGGAGCCGGAAGCGTTCGGGCTCGTGCCGCAGGACGCGGTGTCGTCGGACT
TCATCCCGTACGGCAACCGTGTCGAGCTGTTCATCGGCACGGTCGTCGGCGCAATCACGTTCTCCGGGTCGGTGATCGCG
TTCGGCAAGCTGTCTGGCAAATACAGGTTCCGGCTGTTCCAGGGCGCGCCGGTCGTGTATGCGGGCCAGCACCTGCTCAA
CCTGATGCTCGCGCTCGCGATGCTCGGCTTCGGCATCCTGTTCTTCGTCACGCAGTCGTGGCTGCCGTTCATCATCATGA
CGGCGATCGCGTTCGCGCTCGGCGTGCTGATCATCATCCCGATCGGCGGCGCGGACATGCCGGTGGTCGTATCGATGCTG
AACTCGTACTCGGGGTGGGCGGCGGCCGGCATCGGCTTCTCGCTGAACAACGCGATGCTGATCATCGCCGGTTCGCTCGT
CGGCTCGTCGGGCGCGATCCTGTCGTACATCATGTGCCACGCGATGAACCGCTCGTTCTTCAACGTGATCCTCGGTGGCT
TCGGCGGTGAGGCGGCCGCCGGTGGCGCGGCAGGTGCGAAGGAGCAGCGGCCGGTGAAGTCGGGCTCGGCCGAAGACGCG
TCGTTCATGCTCGGCAACGCGGAAACGGTCGTGATCGTGCCGGGATACGGGCTGGCCGTGGCCCGTGCGCAGCACGCGCT
GAAGGAACTGACCGACAAGCTGGTCGAGAAGGGCATCGACGTGAAGTACGCGATCCATCCGGTCGCGGGGCGGATGCCGG
GGCACATGAACGTGCTGCTCGCGGAAGCGGAAGTGCCGTACGAGATCGTGCACGAGATGGAGGACATCAACGGCGAATTC
GGCCTGGTCGACGTGGTGCTCGTGCTCGGCGCGAACGATGTCGTGAACCCGGCCGCAAAGAACGATCCGGCGTCGCCGAT
CGCGGGGATGCCGATTATCGAGGCGTACAAGGCGCGCACGGTGATCGTCAACAAGCGCTCGATGGCGGCCGGCTACGCGG
GGCTCGACAACGATCTCTTCTACATGGACAAGACGATGATGGTGTTCGGCGATGCGAAGAAGGTCATCGAGGACATGGTG
AAGTCGGTCGAATGA

Upstream 100 bases:

>100_bases
CCGTCAACGTGTTCGGCGGGTTCCTCGTGACGAGGCGCATGCTCGAGATGTTCCGCAAGAAGGCGCCCAGGCAGGCCGAG
GGCGGCAAGGAGGGCGCGCG

Downstream 100 bases:

>100_bases
GGCACGCACGCTCGCACGCACGAGCGACGCGGCTGCCTGCTTCGACTTCCGGGCAGCCTGTGACCGGACAGGCCCGACCG
GCGCAAGCCGGCCGGGTCTT

Product: NAD(P) transhydrogenase, beta subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMAGMAIAILTTIALIVKQAEWLGANLPLGIALVLGALIVGGGV
GAFVAARVEMTKMPELVAAMHSLIGLAAVCIAYAVVSEPEAFGLVPQDAVSSDFIPYGNRVELFIGTVVGAITFSGSVIA
FGKLSGKYRFRLFQGAPVVYAGQHLLNLMLALAMLGFGILFFVTQSWLPFIIMTAIAFALGVLIIIPIGGADMPVVVSML
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAAGGAAGAKEQRPVKSGSAEDA
SFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVEKGIDVKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEF
GLVDVVLVLGANDVVNPAAKNDPASPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNDLFYMDKTMMVFGDAKKVIEDMV
KSVE

Sequences:

>Translated_484_residues
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMAGMAIAILTTIALIVKQAEWLGANLPLGIALVLGALIVGGGV
GAFVAARVEMTKMPELVAAMHSLIGLAAVCIAYAVVSEPEAFGLVPQDAVSSDFIPYGNRVELFIGTVVGAITFSGSVIA
FGKLSGKYRFRLFQGAPVVYAGQHLLNLMLALAMLGFGILFFVTQSWLPFIIMTAIAFALGVLIIIPIGGADMPVVVSML
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAAGGAAGAKEQRPVKSGSAEDA
SFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVEKGIDVKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEF
GLVDVVLVLGANDVVNPAAKNDPASPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNDLFYMDKTMMVFGDAKKVIEDMV
KSVE
>Mature_483_residues
SMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMAGMAIAILTTIALIVKQAEWLGANLPLGIALVLGALIVGGGVG
AFVAARVEMTKMPELVAAMHSLIGLAAVCIAYAVVSEPEAFGLVPQDAVSSDFIPYGNRVELFIGTVVGAITFSGSVIAF
GKLSGKYRFRLFQGAPVVYAGQHLLNLMLALAMLGFGILFFVTQSWLPFIIMTAIAFALGVLIIIPIGGADMPVVVSMLN
SYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAAGGAAGAKEQRPVKSGSAEDAS
FMLGNAETVVIVPGYGLAVARAQHALKELTDKLVEKGIDVKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFG
LVDVVLVLGANDVVNPAAKNDPASPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNDLFYMDKTMMVFGDAKKVIEDMVK
SVE

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=493, Percent_Identity=45.0304259634888, Blast_Score=391, Evalue=1e-109,
Organism=Homo sapiens, GI122939153, Length=493, Percent_Identity=45.0304259634888, Blast_Score=391, Evalue=1e-109,
Organism=Escherichia coli, GI1787886, Length=488, Percent_Identity=49.3852459016393, Blast_Score=442, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17550456, Length=481, Percent_Identity=42.6195426195426, Blast_Score=354, Evalue=5e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 50656; Mature: 50524

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMAGMAIAILTTIALIVKQAEWLG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
ANLPLGIALVLGALIVGGGVGAFVAARVEMTKMPELVAAMHSLIGLAAVCIAYAVVSEPE
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AFGLVPQDAVSSDFIPYGNRVELFIGTVVGAITFSGSVIAFGKLSGKYRFRLFQGAPVVY
HCCCCCCHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEE
AGQHLLNLMLALAMLGFGILFFVTQSWLPFIIMTAIAFALGVLIIIPIGGADMPVVVSML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAA
HCCCCCCHHCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
GGAAGAKEQRPVKSGSAEDASFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVEKGID
CCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
VKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFGLVDVVLVLGANDVVNPAAK
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCC
NDPASPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNDLFYMDKTMMVFGDAKKVIEDMV
CCCCCCCCCCCHHHHHCCEEEEEECHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHH
KSVE
HHCC
>Mature Secondary Structure 
SMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMAGMAIAILTTIALIVKQAEWLG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
ANLPLGIALVLGALIVGGGVGAFVAARVEMTKMPELVAAMHSLIGLAAVCIAYAVVSEPE
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AFGLVPQDAVSSDFIPYGNRVELFIGTVVGAITFSGSVIAFGKLSGKYRFRLFQGAPVVY
HCCCCCCHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEE
AGQHLLNLMLALAMLGFGILFFVTQSWLPFIIMTAIAFALGVLIIIPIGGADMPVVVSML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAA
HCCCCCCHHCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
GGAAGAKEQRPVKSGSAEDASFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVEKGID
CCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
VKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFGLVDVVLVLGANDVVNPAAK
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCC
NDPASPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNDLFYMDKTMMVFGDAKKVIEDMV
CCCCCCCCCCCHHHHHCCEEEEEECHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHH
KSVE
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]