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The map label for this gene is ruvA

Identifier: 78065251

GI number: 78065251

Start: 670307

End: 670888

Strand: Reverse

Name: ruvA

Synonym: Bcep18194_A3775

Alternate gene names: 78065251

Gene position: 670888-670307 (Counterclockwise)

Preceding gene: 78065252

Following gene: 78065250

Centisome position: 18.16

GC content: 65.81

Gene sequence:

>582_bases
ATGATCGGTCGCATCGCCGGCATCCTGCTCGAAAAGAACCCGCCTCACCTGCTCGTCGACTGCAACGGCGTCGGCTACGA
AATCGACGTGCCGATGAGTACCTTCTACAACCTGCCGCAAAACGGCGAGCGCGTCGTACTGCTCACGCAGCAGATCGTCC
GCGAGGACGCGAACCTGCTGTACGGCTTCCTGACGCCGCAGGAGCGCACGACCTTCCGCGAGCTGCTGAAGATCACCGGC
ATCGGCGCACGCATGGCACTCGCCGTGCTGTCCGGCATGAGCGTGCAGGAACTCGCGCAAGCCGTGACGATGCAGGACGC
CGCGCGCCTCACGCGCCTGCCCGGCATCGGCAAGAAGACGGCCGAGCGCCTGCTGCTCGAACTGAAGGGCAAGCTCGGCG
CCGATCTCGGCGAGCTCGCCGGCGCCGCGTCGCCGTCCGACCACGCAACCGACATCCTCAACGCGCTGCTCGCGCTCGGC
TATTCCGAAAAGGAAGGCCTCGCCGCGATCAAGAACGTGCCGGCCGGCACCGGCGTATCCGAAGGCATCAAGCTCGCATT
GAAGGCGTTGTCGAAGGTCTGA

Upstream 100 bases:

>100_bases
GCACACGCGACGTACATCGCCCCGGCCGGATGGCCGACTCCGTCGGCATAGCGCCGCACGTGCGCTACACTCGCGCTTTC
TTCCTCGCATCAAGCCATCC

Downstream 100 bases:

>100_bases
CCCACGCACGATGCCCGCATGACGCACCGCCAGCCGGTGCGTTGAAGCCAGTGTCGCGCGGCCGCGCAGCGCTCGCCAGT
CGGCCGTTCGGCCAGGTGGG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQNGERVVLLTQQIVREDANLLYGFLTPQERTTFRELLKITG
IGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKTAERLLLELKGKLGADLGELAGAASPSDHATDILNALLALG
YSEKEGLAAIKNVPAGTGVSEGIKLALKALSKV

Sequences:

>Translated_193_residues
MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQNGERVVLLTQQIVREDANLLYGFLTPQERTTFRELLKITG
IGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKTAERLLLELKGKLGADLGELAGAASPSDHATDILNALLALG
YSEKEGLAAIKNVPAGTGVSEGIKLALKALSKV
>Mature_193_residues
MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQNGERVVLLTQQIVREDANLLYGFLTPQERTTFRELLKITG
IGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKTAERLLLELKGKLGADLGELAGAASPSDHATDILNALLALG
YSEKEGLAAIKNVPAGTGVSEGIKLALKALSKV

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=201, Percent_Identity=45.273631840796, Blast_Score=172, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 20487; Mature: 20487

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQNGERVVLLTQQIVREDANLL
CCCHHEEEEECCCCCEEEEECCCCCEEEECCHHHHHCCCCCCCEEEEEHHHHHHHHHHHE
YGFLTPQERTTFRELLKITGIGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKT
EEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLLELKGKLGADLGELAGAASPSDHATDILNALLALGYSEKEGLAAIKNVPAGTGVS
HHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHH
EGIKLALKALSKV
HHHHHHHHHHHCC
>Mature Secondary Structure
MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQNGERVVLLTQQIVREDANLL
CCCHHEEEEECCCCCEEEEECCCCCEEEECCHHHHHCCCCCCCEEEEEHHHHHHHHHHHE
YGFLTPQERTTFRELLKITGIGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKT
EEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLLELKGKLGADLGELAGAASPSDHATDILNALLALGYSEKEGLAAIKNVPAGTGVS
HHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHH
EGIKLALKALSKV
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA