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The map label for this gene is gltJ [H]

Identifier: 78065232

GI number: 78065232

Start: 649205

End: 649945

Strand: Direct

Name: gltJ [H]

Synonym: Bcep18194_A3756

Alternate gene names: 78065232

Gene position: 649205-649945 (Clockwise)

Preceding gene: 78065231

Following gene: 78065233

Centisome position: 17.57

GC content: 61.81

Gene sequence:

>741_bases
ATGTCTTACCACTGGAACTGGGGCATCTTCCTGAGCCCCGTATCGACCGGCGAGCCGACGACTTATTTCGGATGGCTGAT
GTCCGGCTTCTGGGTGACCATCGAAGTGTCGCTCGTTGCCTGGGTCATCGCGCTGATCGTCGGTTCGCTGTTCGGCGTGC
TGCGCACCGTGCCGAACAAATGGCTGTCCGCGATCGGTACCCTGTACGTGTCGATTTTCCGGAACATTCCGCTGATCGTG
CAGTTCTTCGTCTGGTATCTCGTGATACCGGAGCTGCTGCCGGCGTCGATCGGCACCTGGATCAAGCAACTGCCGCCCAC
CACGCAGTTCTTTACCGCGTCGATCATCTGTCTCGGCCTGTTCACGGGCGCGCGCGTGTGCGAACAGGTGCGCTCGGGGA
TCAACGCGCTGCCGAAGGGCCAGCGTGCCGCCGGCCTCGCGATGGGTTTCACGCAATGGCAGACGTACCGCTACGTGCTG
CTGCCCGTTGCGTACCGGATCATCGTGCCGCCGCTCACGTCGGAATTCCTGAACATCTTCAAGAACTCCGCCGTCGCGTC
GACGATCGGCCTGCTCGACCTGTCCGCGCAAGCGCGCCAGCTCGTCGACTACACCGCGCAGACGTATGAGTCGTTCATTG
CGGTGACGCTCGCCTACGTGATCATCAACCTCGTCGTGATGTCGTTCATGCGCTGGATCGAAGGCCGTACGCGGCTGCCC
GGCTATATCGGAGGCAAGTGA

Upstream 100 bases:

>100_bases
CAAGGCGCTCGACTGACCGCACGGCCGTTGATGCAGAAATGACGCTAATGAGACGGAAGAGGCCCCGCTTCTTCCGTCTC
TTTTTGCTGGAGTCTTGCCC

Downstream 100 bases:

>100_bases
TGCATCAGTTCGACTGGAGTAGTATTCCCGGCGCGCTGCCGACGCTGTGGACGGGGGCGGTCGTCACGTTCCAGATCACG
CTGATCGCGATCGTGGTCGG

Product: ABC amino acid transporter, inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSYHWNWGIFLSPVSTGEPTTYFGWLMSGFWVTIEVSLVAWVIALIVGSLFGVLRTVPNKWLSAIGTLYVSIFRNIPLIV
QFFVWYLVIPELLPASIGTWIKQLPPTTQFFTASIICLGLFTGARVCEQVRSGINALPKGQRAAGLAMGFTQWQTYRYVL
LPVAYRIIVPPLTSEFLNIFKNSAVASTIGLLDLSAQARQLVDYTAQTYESFIAVTLAYVIINLVVMSFMRWIEGRTRLP
GYIGGK

Sequences:

>Translated_246_residues
MSYHWNWGIFLSPVSTGEPTTYFGWLMSGFWVTIEVSLVAWVIALIVGSLFGVLRTVPNKWLSAIGTLYVSIFRNIPLIV
QFFVWYLVIPELLPASIGTWIKQLPPTTQFFTASIICLGLFTGARVCEQVRSGINALPKGQRAAGLAMGFTQWQTYRYVL
LPVAYRIIVPPLTSEFLNIFKNSAVASTIGLLDLSAQARQLVDYTAQTYESFIAVTLAYVIINLVVMSFMRWIEGRTRLP
GYIGGK
>Mature_245_residues
SYHWNWGIFLSPVSTGEPTTYFGWLMSGFWVTIEVSLVAWVIALIVGSLFGVLRTVPNKWLSAIGTLYVSIFRNIPLIVQ
FFVWYLVIPELLPASIGTWIKQLPPTTQFFTASIICLGLFTGARVCEQVRSGINALPKGQRAAGLAMGFTQWQTYRYVLL
PVAYRIIVPPLTSEFLNIFKNSAVASTIGLLDLSAQARQLVDYTAQTYESFIAVTLAYVIINLVVMSFMRWIEGRTRLPG
YIGGK

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786874, Length=247, Percent_Identity=63.5627530364373, Blast_Score=325, Evalue=1e-90,
Organism=Escherichia coli, GI1788226, Length=215, Percent_Identity=29.7674418604651, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787030, Length=214, Percent_Identity=28.0373831775701, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1786873, Length=217, Percent_Identity=26.2672811059908, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994930, Length=127, Percent_Identity=37.007874015748, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788645, Length=224, Percent_Identity=29.0178571428571, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082239, Length=175, Percent_Identity=28, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788646, Length=219, Percent_Identity=26.9406392694064, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1787087, Length=224, Percent_Identity=23.6607142857143, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787086, Length=221, Percent_Identity=24.4343891402715, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27534; Mature: 27403

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure 
SYHWNWGIFLSPVSTGEPTTYFGWLMSGFWVTIEVSLVAWVIALIVGSLFGVLRTVPNK
CEEECCCEEECCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLSAIGTLYVSIFRNIPLIVQFFVWYLVIPELLPASIGTWIKQLPPTTQFFTASIICLGL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FTGARVCEQVRSGINALPKGQRAAGLAMGFTQWQTYRYVLLPVAYRIIVPPLTSEFLNIF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KNSAVASTIGLLDLSAQARQLVDYTAQTYESFIAVTLAYVIINLVVMSFMRWIEGRTRLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GYIGGK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]