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The map label for this gene is gltK [H]

Identifier: 78065233

GI number: 78065233

Start: 649945

End: 650622

Strand: Direct

Name: gltK [H]

Synonym: Bcep18194_A3757

Alternate gene names: 78065233

Gene position: 649945-650622 (Clockwise)

Preceding gene: 78065232

Following gene: 78065234

Centisome position: 17.59

GC content: 64.16

Gene sequence:

>678_bases
ATGCATCAGTTCGACTGGAGTAGTATTCCCGGCGCGCTGCCGACGCTGTGGACGGGGGCGGTCGTCACGTTCCAGATCAC
GCTGATCGCGATCGTGGTCGGGATCGTCTGGGGCACGCTGCTGGCGCTGATGCGGCTGTCGGGTGTGAAGCCGCTCGCGT
GGTTCGCGCAGGGCTACGTGACGGTGTTTCGCTCGATCCCGCTCGTGATGGTGCTGCTGTGGTTCTTCCTGATCGTGCCG
CAGCTGCTGCAGGGCGTGCTCGGGCTGTCGCCGACGATCGACATCCGTCTTGCGTCGGCGATGGTCGCGTTCTCGCTGTT
CGAAGCCGCGTATTATTCCGAGATCATCCGCGCCGGCATCCAGGCGGTGCCGCGCGGGCAGGCGAACGCCGCGTTTGCGC
TCGGCATGAACTACGCGCAGGCGATGCGCCTCGTGATCCTGCCGCAGGCGTTCCGCGCGATGGTGCCGCTGCTGCTCACG
CAGGCGATCGTCCTGTTCCAGGATACGTCGCTCGTGTACGTGATCAGTCTCGCGGACTTCTTCCGCACGGCGGCCAACAT
CGGCGATCGCGACGGCACGACCGTCGAGATGGTCCTGTTCGCCGGCGCATGCTATTTCGTGATTTGCTCGTTGGCGTCTG
CACTCGTCAAGGGTCTCCAGAAAAAGGTCACAAGATGA

Upstream 100 bases:

>100_bases
CGGTGACGCTCGCCTACGTGATCATCAACCTCGTCGTGATGTCGTTCATGCGCTGGATCGAAGGCCGTACGCGGCTGCCC
GGCTATATCGGAGGCAAGTG

Downstream 100 bases:

>100_bases
TTTCCATCAAGAACGTTTCGAAGTGGTACGGCCAGTTTCAGGTTCTCACCGACTGCACGACCGAGGTCAAGAAAGGCGAA
GTGGTCGTCGTGTGCGGCCC

Product: ABC amino acid transporter, inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MHQFDWSSIPGALPTLWTGAVVTFQITLIAIVVGIVWGTLLALMRLSGVKPLAWFAQGYVTVFRSIPLVMVLLWFFLIVP
QLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQANAAFALGMNYAQAMRLVILPQAFRAMVPLLLT
QAIVLFQDTSLVYVISLADFFRTAANIGDRDGTTVEMVLFAGACYFVICSLASALVKGLQKKVTR

Sequences:

>Translated_225_residues
MHQFDWSSIPGALPTLWTGAVVTFQITLIAIVVGIVWGTLLALMRLSGVKPLAWFAQGYVTVFRSIPLVMVLLWFFLIVP
QLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQANAAFALGMNYAQAMRLVILPQAFRAMVPLLLT
QAIVLFQDTSLVYVISLADFFRTAANIGDRDGTTVEMVLFAGACYFVICSLASALVKGLQKKVTR
>Mature_225_residues
MHQFDWSSIPGALPTLWTGAVVTFQITLIAIVVGIVWGTLLALMRLSGVKPLAWFAQGYVTVFRSIPLVMVLLWFFLIVP
QLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQANAAFALGMNYAQAMRLVILPQAFRAMVPLLLT
QAIVLFQDTSLVYVISLADFFRTAANIGDRDGTTVEMVLFAGACYFVICSLASALVKGLQKKVTR

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=71.1711711711712, Blast_Score=320, Evalue=4e-89,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=36.4485981308411, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082239, Length=210, Percent_Identity=33.8095238095238, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1786874, Length=214, Percent_Identity=29.9065420560748, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787030, Length=226, Percent_Identity=29.2035398230088, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787087, Length=227, Percent_Identity=28.6343612334802, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788645, Length=217, Percent_Identity=25.8064516129032, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994930, Length=129, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=25.2336448598131, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788646, Length=208, Percent_Identity=25, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24523; Mature: 24523

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQFDWSSIPGALPTLWTGAVVTFQITLIAIVVGIVWGTLLALMRLSGVKPLAWFAQGYV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TVFRSIPLVMVLLWFFLIVPQLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVPRGQANAAFALGMNYAQAMRLVILPQAFRAMVPLLLTQAIVLFQDTSLVYVISLADF
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FRTAANIGDRDGTTVEMVLFAGACYFVICSLASALVKGLQKKVTR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHQFDWSSIPGALPTLWTGAVVTFQITLIAIVVGIVWGTLLALMRLSGVKPLAWFAQGYV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TVFRSIPLVMVLLWFFLIVPQLLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVPRGQANAAFALGMNYAQAMRLVILPQAFRAMVPLLLTQAIVLFQDTSLVYVISLADF
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FRTAANIGDRDGTTVEMVLFAGACYFVICSLASALVKGLQKKVTR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]