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The map label for this gene is qseD [H]

Identifier: 78065229

GI number: 78065229

Start: 645457

End: 646410

Strand: Direct

Name: qseD [H]

Synonym: Bcep18194_A3753

Alternate gene names: 78065229

Gene position: 645457-646410 (Clockwise)

Preceding gene: 78065227

Following gene: 78065230

Centisome position: 17.47

GC content: 68.76

Gene sequence:

>954_bases
ATGGAACTGAAATGGCTCGAAGACTTCGTTTCGCTCGCGGAAACGCGCAGCTTTAGCCGGTCCGCCGAGCTGCGGCACGT
GTCGCAGCCGGCGTTTTCGCGGCGCATCCAGGCGCTCGAGGCATGGCTCGCGACCGAACTGATCGATCGTTCGGTCTATC
CGACGCGGCTCACGCAGGCCGGGCAGATCTTCTACGAACAGGCGCTGACGATGCTGTCGCAGGCGCACGAGGCGCGCACG
CTGCTGCGCGGCCACGTCGGCGCGCCGGTGCCGACGATCGAGTTCGCGGTGCCGCACACGCTGTCGCTCACGTATTTCCC
GCGCTGGCTGCAGCGGATCGAGGCGAAGATGGGGCAGGTCCACACGCGGCTGCGCGCGCTGAACGTGCACGACGCGGTGC
TGTCGCTCGTCGAGGGCGGCTGCGATCTCGTGATGGGCTACCACCACCCGAGCCATCCGGTCGCGCTCGACCCGGCGCGC
TACGACATGCTGATCCTCGGCAGCGAGCCGATCAGCCCGTTCTCGGCGCCGGGCCGCGCGGGGCGGCCGCGCTATACGCT
GCCCGGTACGGCCGATGCACGCGTGCCGTACCTGTCATATACGCCGAATGCGTATCTCGGCCGGATGACGGAGGTCATCG
TCGCGAATGCGACGACCCCGCTGTTCCTCGATCGCGTCTACGAAACCGACATGGCCGAAGGGCTGAAGGCGATGGCGCTC
GCGGGCCACGGTATCGCGTTCCTGCCGCACAGCGCGGTCGAGGACGCGGTCGCGGGCGGCCGCCTGATCCGGCTCGACCG
GTCGGTGCGCGGTGGCGCGTACCCGTTCACGCTGACGATGGAGATCCGGCTGTACTGCGACAAGCTCGCGCTGCAGGGCG
ACGACCCGCGGCAGAAGCTCGTGCGCGCGCTGTGGGACGTCGTACGCGACGAACTGCGCGAAACCGCGGGTTAA

Upstream 100 bases:

>100_bases
TCGCGACGGGGCGCCGGGCCGCTCGCCGCACCGCCGCCCGTGCCCGCCCGCCGGTAGAATGCAGGCTTCTTCCCGACCGC
CGCCCGCCGCGCCCGCCTGC

Downstream 100 bases:

>100_bases
CCGTCGGCGGTTAACCACCCGCCGCACGGCCCGGCCGGCTGTCGTCGAGCTTGCGTCGCCTGTCGGGCGGCTGTCCGGCG
GCCCTCCCGCCTCCACGAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQAGQIFYEQALTMLSQAHEART
LLRGHVGAPVPTIEFAVPHTLSLTYFPRWLQRIEAKMGQVHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLILGSEPISPFSAPGRAGRPRYTLPGTADARVPYLSYTPNAYLGRMTEVIVANATTPLFLDRVYETDMAEGLKAMAL
AGHGIAFLPHSAVEDAVAGGRLIRLDRSVRGGAYPFTLTMEIRLYCDKLALQGDDPRQKLVRALWDVVRDELRETAG

Sequences:

>Translated_317_residues
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQAGQIFYEQALTMLSQAHEART
LLRGHVGAPVPTIEFAVPHTLSLTYFPRWLQRIEAKMGQVHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLILGSEPISPFSAPGRAGRPRYTLPGTADARVPYLSYTPNAYLGRMTEVIVANATTPLFLDRVYETDMAEGLKAMAL
AGHGIAFLPHSAVEDAVAGGRLIRLDRSVRGGAYPFTLTMEIRLYCDKLALQGDDPRQKLVRALWDVVRDELRETAG
>Mature_317_residues
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQAGQIFYEQALTMLSQAHEART
LLRGHVGAPVPTIEFAVPHTLSLTYFPRWLQRIEAKMGQVHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLILGSEPISPFSAPGRAGRPRYTLPGTADARVPYLSYTPNAYLGRMTEVIVANATTPLFLDRVYETDMAEGLKAMAL
AGHGIAFLPHSAVEDAVAGGRLIRLDRSVRGGAYPFTLTMEIRLYCDKLALQGDDPRQKLVRALWDVVRDELRETAG

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=268, Percent_Identity=34.7014925373134, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=25.6944444444444, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790399, Length=151, Percent_Identity=31.1258278145695, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787879, Length=268, Percent_Identity=29.1044776119403, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35331; Mature: 35331

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GQIFYEQALTMLSQAHEARTLLRGHVGAPVPTIEFAVPHTLSLTYFPRWLQRIEAKMGQV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHH
HTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPARYDMLILGSEPISPFSAPGRA
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCC
GRPRYTLPGTADARVPYLSYTPNAYLGRMTEVIVANATTPLFLDRVYETDMAEGLKAMAL
CCCCEECCCCCCCCCCEEEECCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
AGHGIAFLPHSAVEDAVAGGRLIRLDRSVRGGAYPFTLTMEIRLYCDKLALQGDDPRQKL
CCCCEEECCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEEEEEHHHHCCCCCHHHHH
VRALWDVVRDELRETAG
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GQIFYEQALTMLSQAHEARTLLRGHVGAPVPTIEFAVPHTLSLTYFPRWLQRIEAKMGQV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHH
HTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPARYDMLILGSEPISPFSAPGRA
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCC
GRPRYTLPGTADARVPYLSYTPNAYLGRMTEVIVANATTPLFLDRVYETDMAEGLKAMAL
CCCCEECCCCCCCCCCEEEECCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
AGHGIAFLPHSAVEDAVAGGRLIRLDRSVRGGAYPFTLTMEIRLYCDKLALQGDDPRQKL
CCCCEEECCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEEEEEHHHHCCCCCHHHHH
VRALWDVVRDELRETAG
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]