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The map label for this gene is gntP [H]

Identifier: 78065224

GI number: 78065224

Start: 639460

End: 640821

Strand: Direct

Name: gntP [H]

Synonym: Bcep18194_A3748

Alternate gene names: 78065224

Gene position: 639460-640821 (Clockwise)

Preceding gene: 78065223

Following gene: 78065225

Centisome position: 17.31

GC content: 64.76

Gene sequence:

>1362_bases
ATGGGGGCTGTCCAAGGCAGCATGCTGCTCGTATTCACGCTGATCGCGATCGCCGCGCTGATCCTGATGATCGCGCGCTA
CAAGATCTACCCGTTCCTGGTGCTGATCATCGTTTCGCTCGGCCTCGGTCTCGTCGTCGGCATGCCGATGGACAAGATCG
TCAAGTCGTTCGAGGCGGGCACCGGCGGCACGCTCGGCCACATCGCGATCGTCGTCGGCCTCGGCACGATGCTCGGCAAG
ATGATGGCCGAATCGGGCGGCGCCGAACGGATCGCGACCACGCTGATCGACTGGTTCGGTGAAAAGAACATCCACTGGGC
GATGATGTTCGTCGCGATCATCGTTGGCCTGCCGGTGTTCTTCGAAGTCGGCTTCGTGCTGCTGATCCCGATCGCGTTCA
ACGTCGCGAAGCGCACCGGCAAGTCGCTGCTCGTCGTCGGCCTGCCGATGGTGGCCGGCCTGTCCGTCGTGCACGGCCTG
ATCCCGCCGCACCCGGCCGCGCTGCTGGCCGTTCAGCAATACGGCGCCGATATCGGCAAGACGATCGCGTTCGGCCTGAT
CGTCGGCGTGCCGACCGCGATCATCGCGGGCCCGCTGTTTGCGCTGACGATCTCGAAGTTCGTGAAGCTGCCGGAGAACA
ACCCGCTCGCCGCTCAGTTCGTCGATACGCACACGGATGGCCGCAAGCGTGAACTGCCGAGCTTCGGCATCACGCTGTTC
ACGATCCTGCTGCCCGTCGTGCTGATGCTCGTCGGCAGCTGGGCCGACCTGCTGTTCACGCCGAAGTCGCTGCCGAACAA
CCTGCTGCGCTTTGCCGGCAACTCGGACGTCGCGCTGCTGATCGCCGTGCTCGTGAGCTTCTTCACGTTCGGCAAGCTGC
AGGGCTTCAACCGCGACCAGATCCAGAAGTTCTGCGGCGAGTGCCTGGCACCGATCGCCGGCATCACGCTGATCGTCGGC
GCGGGTGGCGGCTTCGGCGGCGTCCTGCGCGACAGCGGGATTTCGCAGCAGATCGTTGAAACCGCGAAGCACGCGCACCT
GTCGCCGCTGCTGCTCGGCTGGTTCGTTGCCGCGCTGATGCGTCTCGCGACGGGTTCGGCGACGGTCGCAATGACGACGG
CCTGCGGCATCGTCGCGCCGATCGCCGCGGCGGCCGGCACGACGGTCAGCCCGGAGCTGCTGGTGCTGGCCACGGGCTCG
GGCTCGCTGATCTTCTCGCACGTGAACGACGGCGGCTTCTGGCTGATCAAGGAATACTTCGGGATGACGGTCGGTCAGAC
GTTCAAGACCTGGTCGTTGCTCGAAACCATCATCTCGGTGCTTGGTCTTGGCTTCACGCTGCTGCTGAGCATGGTTCTGT
AA

Upstream 100 bases:

>100_bases
GTCCTGACGGGGTGGGTACCCCCCGTGTTCCGGAGACCTGCATAGCCGGGCATACTCGCAACAACTCGCCCGGTTCGAAC
AATTCTAGGAGGAGTGCCAC

Downstream 100 bases:

>100_bases
CAAGGGGTAGGCAATGATTCTGATCGCAATGGGCGTGTCGGGTGCGGGCAAGTCGCTAATCGGCGAAATGCTGGCGGAAC
GCCTGTCGTGCAGCTATACC

Product: gluconate transporter

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MGAVQGSMLLVFTLIAIAALILMIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFEAGTGGTLGHIAIVVGLGTMLGK
MMAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGL
IPPHPAALLAVQQYGADIGKTIAFGLIVGVPTAIIAGPLFALTISKFVKLPENNPLAAQFVDTHTDGRKRELPSFGITLF
TILLPVVLMLVGSWADLLFTPKSLPNNLLRFAGNSDVALLIAVLVSFFTFGKLQGFNRDQIQKFCGECLAPIAGITLIVG
AGGGFGGVLRDSGISQQIVETAKHAHLSPLLLGWFVAALMRLATGSATVAMTTACGIVAPIAAAAGTTVSPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISVLGLGFTLLLSMVL

Sequences:

>Translated_453_residues
MGAVQGSMLLVFTLIAIAALILMIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFEAGTGGTLGHIAIVVGLGTMLGK
MMAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGL
IPPHPAALLAVQQYGADIGKTIAFGLIVGVPTAIIAGPLFALTISKFVKLPENNPLAAQFVDTHTDGRKRELPSFGITLF
TILLPVVLMLVGSWADLLFTPKSLPNNLLRFAGNSDVALLIAVLVSFFTFGKLQGFNRDQIQKFCGECLAPIAGITLIVG
AGGGFGGVLRDSGISQQIVETAKHAHLSPLLLGWFVAALMRLATGSATVAMTTACGIVAPIAAAAGTTVSPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISVLGLGFTLLLSMVL
>Mature_452_residues
GAVQGSMLLVFTLIAIAALILMIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFEAGTGGTLGHIAIVVGLGTMLGKM
MAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGLI
PPHPAALLAVQQYGADIGKTIAFGLIVGVPTAIIAGPLFALTISKFVKLPENNPLAAQFVDTHTDGRKRELPSFGITLFT
ILLPVVLMLVGSWADLLFTPKSLPNNLLRFAGNSDVALLIAVLVSFFTFGKLQGFNRDQIQKFCGECLAPIAGITLIVGA
GGGFGGVLRDSGISQQIVETAKHAHLSPLLLGWFVAALMRLATGSATVAMTTACGIVAPIAAAAGTTVSPELLVLATGSG
SLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISVLGLGFTLLLSMVL

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=450, Percent_Identity=47.7777777777778, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1790716, Length=446, Percent_Identity=41.0313901345291, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1788707, Length=445, Percent_Identity=42.4719101123596, Blast_Score=308, Evalue=3e-85,
Organism=Escherichia coli, GI2367370, Length=430, Percent_Identity=40.9302325581395, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1790776, Length=432, Percent_Identity=34.7222222222222, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI48994939, Length=424, Percent_Identity=37.2641509433962, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1789097, Length=446, Percent_Identity=34.304932735426, Blast_Score=203, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47572; Mature: 47441

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GAVQGSMLLVFTLIAIAALILMIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFEAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC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CCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA