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The map label for this gene is asd [H]

Identifier: 78048431

GI number: 78048431

Start: 3268322

End: 3269347

Strand: Reverse

Name: asd [H]

Synonym: XCV2875

Alternate gene names: 78048431

Gene position: 3269347-3268322 (Counterclockwise)

Preceding gene: 78048432

Following gene: 78048430

Centisome position: 63.13

GC content: 65.3

Gene sequence:

>1026_bases
ATGAGCAACGAAAACCGTCGTTTCAACGTCGCCGTCGTGGGCGCCACCGGCGCTGTCGGCGAGACCATGCTGAGCATACT
GGCCGAGCGCAACTTCCCGGTCGCCACCCTGTACGCGCTGGCGTCGTCGCGCTCGGCGGGCGGGCAGGTGGAGTTCAATG
GCGGCAAGGTCGATGTGCTGGACCTGGCCGAGTTCGACCCCGCCGGCGTGGACATCGCGCTGTTCTCCGCCGGCGGCAGC
GTGTCCAAGGAATACGGCCCCAAGTTCGCCGCGGCCGGTGCGGTGGTGATCGATAACTCCTCGGCCTTCCGCTATGACGA
CGACGTGCCGCTGGTGGTGTCCGAGGTCAACCCGGAAGCGCTCAAGCAGCGCCCGCGCGGCATCATCGCCAATCCCAATT
GCTCGACCATGCAAATGCTGGTGGCACTGGGCCCGATCCACCGCCAGTACGGCATCGAGCGTATCAACGTGGCGACCTAC
CAGTCGGTCTCCGGCGGCGGGCGTTCGGCGATGGAAGAACTGGGCAAGCAGACCAGCGAGTTGTTGAGCTTTCAGGACAT
CGACCCGCAGCGGTTCCCGGTGCAGATCGCCTTCAACCTGATCCCGCACATCGACGACTTCCAGGACAACGGCTACACCA
AGGAAGAGATGAAGCTGGTCTGGGAGACCCGCAAGATCCTCGGCGACGACAGCATCCAGGTGAACCCCACCGCGGTGCGC
GTGCCGGTGTTCTACGGCCATTCCGAAGCGGTGGCGATCGAGACCCGCGACAAGATCACCGTGGAGCAGGCGCGCGCGCT
GCTGGCAGCGTCGCCTGGCGTGGAAGTGGTGGACGAGCGCAAGCCCGGCGGCTACCCGACGCCGGTCACGCATGCTTCCG
GCAAGGATGCGGTGTTCGTCGGCCGCATCCGTGAAGACTTTTCGCATCCGCGCGGCCTGAACTTGTGGATCGTCTCCGAC
AATATCCGCAAGGGCGCTGCGCTCAACGCCGTGCAGCTGGCCGAACTGGTCGCACAGGAAGGCTAA

Upstream 100 bases:

>100_bases
TTTCGACCAAACGATAGGGAACCTCCGCGGCCAGCGTTGGAGGTTCCCCGAACCCAGCGCGCAGTGCTTCCTCATTTCCC
CTTTCGATAAAGACAAACTC

Downstream 100 bases:

>100_bases
GCAGCACGACAAAGACGACCGCGCAGCCGCCATGCGTGCGCGCGGCCGGCGCCTGGTGCAGCAGGCGTCACCCGGCCACT
GCGATGCTGAGCGCGCCGTT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSNENRRFNVAVVGATGAVGETMLSILAERNFPVATLYALASSRSAGGQVEFNGGKVDVLDLAEFDPAGVDIALFSAGGS
VSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEALKQRPRGIIANPNCSTMQMLVALGPIHRQYGIERINVATY
QSVSGGGRSAMEELGKQTSELLSFQDIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDDSIQVNPTAVR
VPVFYGHSEAVAIETRDKITVEQARALLAASPGVEVVDERKPGGYPTPVTHASGKDAVFVGRIREDFSHPRGLNLWIVSD
NIRKGAALNAVQLAELVAQEG

Sequences:

>Translated_341_residues
MSNENRRFNVAVVGATGAVGETMLSILAERNFPVATLYALASSRSAGGQVEFNGGKVDVLDLAEFDPAGVDIALFSAGGS
VSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEALKQRPRGIIANPNCSTMQMLVALGPIHRQYGIERINVATY
QSVSGGGRSAMEELGKQTSELLSFQDIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDDSIQVNPTAVR
VPVFYGHSEAVAIETRDKITVEQARALLAASPGVEVVDERKPGGYPTPVTHASGKDAVFVGRIREDFSHPRGLNLWIVSD
NIRKGAALNAVQLAELVAQEG
>Mature_340_residues
SNENRRFNVAVVGATGAVGETMLSILAERNFPVATLYALASSRSAGGQVEFNGGKVDVLDLAEFDPAGVDIALFSAGGSV
SKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEALKQRPRGIIANPNCSTMQMLVALGPIHRQYGIERINVATYQ
SVSGGGRSAMEELGKQTSELLSFQDIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDDSIQVNPTAVRV
PVFYGHSEAVAIETRDKITVEQARALLAASPGVEVVDERKPGGYPTPVTHASGKDAVFVGRIREDFSHPRGLNLWIVSDN
IRKGAALNAVQLAELVAQEG

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=335, Percent_Identity=40.8955223880597, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=29.0140845070423, Blast_Score=109, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320362, Length=391, Percent_Identity=29.6675191815857, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36727; Mature: 36596

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNENRRFNVAVVGATGAVGETMLSILAERNFPVATLYALASSRSAGGQVEFNGGKVDVL
CCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCEEEECCCEEEEE
DLAEFDPAGVDIALFSAGGSVSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEA
EECCCCCCCCEEEEEECCCCCCHHHCCCCHHCCEEEEECCCCEEECCCCCEEEECCCHHH
LKQRPRGIIANPNCSTMQMLVALGPIHRQYGIERINVATYQSVSGGGRSAMEELGKQTSE
HHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHHHHH
LLSFQDIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDDSIQVNPTAVR
HHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCEEEE
VPVFYGHSEAVAIETRDKITVEQARALLAASPGVEVVDERKPGGYPTPVTHASGKDAVFV
EEEEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEEE
GRIREDFSHPRGLNLWIVSDNIRKGAALNAVQLAELVAQEG
EEHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SNENRRFNVAVVGATGAVGETMLSILAERNFPVATLYALASSRSAGGQVEFNGGKVDVL
CCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCEEEECCCEEEEE
DLAEFDPAGVDIALFSAGGSVSKEYGPKFAAAGAVVIDNSSAFRYDDDVPLVVSEVNPEA
EECCCCCCCCEEEEEECCCCCCHHHCCCCHHCCEEEEECCCCEEECCCCCEEEECCCHHH
LKQRPRGIIANPNCSTMQMLVALGPIHRQYGIERINVATYQSVSGGGRSAMEELGKQTSE
HHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCHHHHHHHHHHHHH
LLSFQDIDPQRFPVQIAFNLIPHIDDFQDNGYTKEEMKLVWETRKILGDDSIQVNPTAVR
HHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCEEEE
VPVFYGHSEAVAIETRDKITVEQARALLAASPGVEVVDERKPGGYPTPVTHASGKDAVFV
EEEEECCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCEEEE
GRIREDFSHPRGLNLWIVSDNIRKGAALNAVQLAELVAQEG
EEHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9573067 [H]