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The map label for this gene is tsf [H]

Identifier: 78047034

GI number: 78047034

Start: 1661107

End: 1661985

Strand: Reverse

Name: tsf [H]

Synonym: XCV1478

Alternate gene names: 78047034

Gene position: 1661985-1661107 (Counterclockwise)

Preceding gene: 78047035

Following gene: 78047033

Centisome position: 32.09

GC content: 63.71

Gene sequence:

>879_bases
ATGGAAATCACTGCTTCCCTGGTCAAGGAACTGCGCGAGCGCACCGGCGCCGGCATGATGGAGTGCAAGAAGGCACTCGT
CGAAAACGCAGGCGACATCGACGCCGCGGCCGAGTGGCTGCGCAAGTCGGGCCTGGCCAAGGCCGACAAGAAGGCTGACC
GCGTCGCCGCCGAAGGCCGCATCGCCACCGCCCAGGCCGGCGGCAAGGCCGTGCTGGTCGAAGTCAATTCCGAGACCGAC
TTCGTCGCCAAGGACGAAAACTTCCTGGCCTTCACCGAGGTCGTGGCCAATGCCGCACTGAACTCGGACGCTGCCGATGC
CGAAGCGCTCAAGAGCGTCAAGCTCGACAGCGGCGAGACCATCGAAGAGCGTCGCGCTGCGGTGATCGCCAAGGTCGGCG
AAAACCTGCAGGTGCGTCGCCTGGTCCGTATCGACAGCGCCAACAACGTCGCGGCCTATGTGCACGGCGGCCGTATCGGC
GTGCTGGTCGAACTGAAGGGTGGCGACATCGAGCTGGCGCGCGGCATCGCCATGCACATTGCGGCGATGAACCCGCCGCA
CGTCAAGGCCTCCGACGTTCCAGCCGAATTCGTTGCCAAGGAAAAGGAAATCGAACTGGCCAAGATGTCCGAAAAGGACA
AGGCCAAGCCGGCCGAGATTCTGGAAAAGATCATCAGCGGCAAGATCAGCAAGATCGTCAACGAAGTGACGCTGTACGGC
CAGCCGTACGTGCTCAACACCGACCAGACCGTCGAGCAGGCAGTCAAGGCCGCCGGCGCCGACGTGATCGGCTTCCAGCG
CCTGGCCGTTGGCGAAGGCATCGAGAAGGTGGTGGAAGACTACGCCGCCGAAGTGATGAAGCAGGCCGGCCTGGCCTGA

Upstream 100 bases:

>100_bases
GAGGCTACTGCATACATCTACGGGGGCGGCGGCATGCCGCACCGTCTCCTACTGGCGGAATCGCTTCCGCCGCACGCATT
CGTCCATATGAGGTAATTCC

Downstream 100 bases:

>100_bases
TCTTCCCCGCTCGGAAAAAAGCCGCGGCATGCCGCGGCTTTTTTTTGCCTGTCGCTCGCGCATCCGCACACTGGCGCGAA
CCTGAAGCGAACGCATCCGG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGRIATAQAGGKAVLVEVNSETD
FVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGETIEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIG
VLVELKGGDIELARGIAMHIAAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYG
QPYVLNTDQTVEQAVKAAGADVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA

Sequences:

>Translated_292_residues
MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGRIATAQAGGKAVLVEVNSETD
FVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGETIEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIG
VLVELKGGDIELARGIAMHIAAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYG
QPYVLNTDQTVEQAVKAAGADVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA
>Mature_292_residues
MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGRIATAQAGGKAVLVEVNSETD
FVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGETIEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIG
VLVELKGGDIELARGIAMHIAAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYG
QPYVLNTDQTVEQAVKAAGADVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=300, Percent_Identity=28.6666666666667, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI291084500, Length=321, Percent_Identity=27.7258566978193, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI291084502, Length=94, Percent_Identity=42.5531914893617, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI291084498, Length=94, Percent_Identity=42.5531914893617, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786366, Length=284, Percent_Identity=50.7042253521127, Blast_Score=255, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17561440, Length=294, Percent_Identity=26.8707482993197, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19921466, Length=305, Percent_Identity=27.8688524590164, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 31034; Mature: 31034

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGR
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
IATAQAGGKAVLVEVNSETDFVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGET
EEEECCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
IEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIGVLVELKGGDIELARGIAMHI
HHHHHHHHHHHHCCCCEEEHEEEECCCCCEEEEEECCEEEEEEEECCCCCHHHHHHHHHE
AAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYG
EECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QPYVLNTDQTVEQAVKAAGADVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA
CCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEITASLVKELRERTGAGMMECKKALVENAGDIDAAAEWLRKSGLAKADKKADRVAAEGR
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCC
IATAQAGGKAVLVEVNSETDFVAKDENFLAFTEVVANAALNSDAADAEALKSVKLDSGET
EEEECCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC
IEERRAAVIAKVGENLQVRRLVRIDSANNVAAYVHGGRIGVLVELKGGDIELARGIAMHI
HHHHHHHHHHHHCCCCEEEHEEEECCCCCEEEEEECCEEEEEEEECCCCCHHHHHHHHHE
AAMNPPHVKASDVPAEFVAKEKEIELAKMSEKDKAKPAEILEKIISGKISKIVNEVTLYG
EECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QPYVLNTDQTVEQAVKAAGADVIGFQRLAVGEGIEKVVEDYAAEVMKQAGLA
CCEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]