Click here to switch to the map view.

The map label for this gene is queC

Identifier: 78044764

GI number: 78044764

Start: 840744

End: 841391

Strand: Direct

Name: queC

Synonym: CHY_0952

Alternate gene names: 78044764

Gene position: 840744-841391 (Clockwise)

Preceding gene: 78044205

Following gene: 78043062

Centisome position: 35.01

GC content: 41.82

Gene sequence:

>648_bases
ATGGAAAAAGCAATTGTGTTACTTTCGGCGGGTCTTGATTCTACGGTTTCCCTTGCTTATGGAGTAAGAAATTTTCAGGT
GGTGCTGGGCCTGACCTTTAATTACGGGCAAAAAGCTTCCCGGAAGGAAATCGAACACAGTAAAAAAATTTTGGATTATT
ACGGTATTCCCCAGGAAGTAATTGAACTACCGTTTTTAAAGAAGATTACCAAAACTTCTCTGGTGGCTGAAGATCAAGAA
ATACCTACTGGTATAGATTTGGAAAGTGCTGCTGCCGTTAAAACCTCAATGGAAAAAGTTTGGGTTCCCAATAGAAATGG
TCTTTTTATTAATATCGCTGCCGCTTATGCCGAAAGTTTGGGAGCAAAATACATAATTACGGGATTTAATGCGGAAGAAG
CAAAAACTTTTAGCGATAACTCGCGGGAGTTTGTGGATGCTGTGAATCACGCTTTAAAATACAGCACCTTAAATCACGTT
CAAGTGGTCAGCTTTACCCAAAATTTAGAAAAATCCGAGATTTACCGCCTGGGAGTTGAACTGGGGGCTCCTCTGGACTT
AATCTGGAGTTGTTACTACGGCGGAGACGAAATGTGCGGGGTATGTGAAAGCTGTTTAAGGCTAAAACGGGCGCGGGGAG
GAAATTAA

Upstream 100 bases:

>100_bases
GAGTTAAAAGCAAAACTTATTGTCTATCCCGAAATAAAACTATGTTCTGTTAAAGTTTGGGAGTCTCCCAATAACGCTGC
TACCTATATGGAGTGATGAT

Downstream 100 bases:

>100_bases
ATGTTTGCTCGCTTTATCGACCAAAAAATTGATTATGACGGATCTCAACTTCGACCTCATTTTATCTACGAAAATTTTGG
TTTAATTGGCGATGCGATAA

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MEKAIVLLSAGLDSTVSLAYGVRNFQVVLGLTFNYGQKASRKEIEHSKKILDYYGIPQEVIELPFLKKITKTSLVAEDQE
IPTGIDLESAAAVKTSMEKVWVPNRNGLFINIAAAYAESLGAKYIITGFNAEEAKTFSDNSREFVDAVNHALKYSTLNHV
QVVSFTQNLEKSEIYRLGVELGAPLDLIWSCYYGGDEMCGVCESCLRLKRARGGN

Sequences:

>Translated_215_residues
MEKAIVLLSAGLDSTVSLAYGVRNFQVVLGLTFNYGQKASRKEIEHSKKILDYYGIPQEVIELPFLKKITKTSLVAEDQE
IPTGIDLESAAAVKTSMEKVWVPNRNGLFINIAAAYAESLGAKYIITGFNAEEAKTFSDNSREFVDAVNHALKYSTLNHV
QVVSFTQNLEKSEIYRLGVELGAPLDLIWSCYYGGDEMCGVCESCLRLKRARGGN
>Mature_215_residues
MEKAIVLLSAGLDSTVSLAYGVRNFQVVLGLTFNYGQKASRKEIEHSKKILDYYGIPQEVIELPFLKKITKTSLVAEDQE
IPTGIDLESAAAVKTSMEKVWVPNRNGLFINIAAAYAESLGAKYIITGFNAEEAKTFSDNSREFVDAVNHALKYSTLNHV
QVVSFTQNLEKSEIYRLGVELGAPLDLIWSCYYGGDEMCGVCESCLRLKRARGGN

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=212, Percent_Identity=30.6603773584906, Blast_Score=91, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_CARHZ (Q3ADI5)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359799.1
- ProteinModelPortal:   Q3ADI5
- SMR:   Q3ADI5
- STRING:   Q3ADI5
- GeneID:   3727888
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0952
- NMPDR:   fig|246194.3.peg.429
- TIGR:   CHY_0952
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK741822
- BioCyc:   CHYD246194:CHY_0952-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 23770; Mature: 23770

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKAIVLLSAGLDSTVSLAYGVRNFQVVLGLTFNYGQKASRKEIEHSKKILDYYGIPQEV
CCCEEEEEECCCCCHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHH
IELPFLKKITKTSLVAEDQEIPTGIDLESAAAVKTSMEKVWVPNRNGLFINIAAAYAESL
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCEEEEEHHHHHHHC
GAKYIITGFNAEEAKTFSDNSREFVDAVNHALKYSTLNHVQVVSFTQNLEKSEIYRLGVE
CCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHHHHHHHH
LGAPLDLIWSCYYGGDEMCGVCESCLRLKRARGGN
CCCCHHHHHEECCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEKAIVLLSAGLDSTVSLAYGVRNFQVVLGLTFNYGQKASRKEIEHSKKILDYYGIPQEV
CCCEEEEEECCCCCHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHH
IELPFLKKITKTSLVAEDQEIPTGIDLESAAAVKTSMEKVWVPNRNGLFINIAAAYAESL
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCEEEEEHHHHHHHC
GAKYIITGFNAEEAKTFSDNSREFVDAVNHALKYSTLNHVQVVSFTQNLEKSEIYRLGVE
CCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCHHHHHHHHHH
LGAPLDLIWSCYYGGDEMCGVCESCLRLKRARGGN
CCCCHHHHHEECCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA