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The map label for this gene is purQ

Identifier: 78043830

GI number: 78043830

Start: 948457

End: 949161

Strand: Direct

Name: purQ

Synonym: CHY_1073

Alternate gene names: 78043830

Gene position: 948457-949161 (Clockwise)

Preceding gene: 78042704

Following gene: 78044209

Centisome position: 39.49

GC content: 49.08

Gene sequence:

>705_bases
ATGAAGTTCGGGGTGGTGGTTTTTCCGGGCTCCAATTGTGATGCCGATTGTTTTCACGTCTTAAAAAACGTCTTTGGCCG
GGAGACGGTGTATATCTGGCATAAAGAGGATAATTTTGATGTTGACTGCATTGTTCTGCCCGGTGGCTTTTCCTACGGCG
ATTATTTGCGGGCCGGGGCGATTGCCCGTTTTAGCCCGGTGATGAAAAAAGTGGTAGAGTTTGCTAATGCCGGAGGTCTG
GTTATCGGTATCTGTAACGGTTTTCAAATCCTTTTAGAAGCGGGGCTTTTACCCGGTGCCATGCTTAGAAATAAAAGCAT
AAATTTCCGGTGCCATGATGTTTACCTGCGGGTAGAAAACAACAATACTCCCTTTACCAGTAAAGCGCATGAGGGACAGG
TGCTGAAAATTCCCATTGCCCACGGGGAGGGGAATTACTACTGCGAGCCGGATACCTTAAAAAAGCTTATTGCCAACGGA
CAGGTGGTGTTTCGGTACTGTAATTCCCGGGGGGAAGTGACCGAGGATGCCAATCCCAATGGTTCCCTTTACAATATTGC
GGGAATCATTAACGAGAAAGGTAACGTCCTCGGTATGATGCCCCATCCGGAGCGCTGCTCGGAGAATATCCTGGGAGGAG
AGGATGGCAGGGTAATCTGGGAATCGATTATCGCGTACTTGGAAAGGGGGGCTAACCGTGGCTAA

Upstream 100 bases:

>100_bases
AATGACTTAAAGGAAATAGAAGAAAGAGTTAAGGAAATGGCCGATAAGCTTTTAGCCAATGTGGTTATTGAAAAATTTAC
GGTGCAGGTGGAGGGTTAAG

Downstream 100 bases:

>100_bases
GTGGCGGGAGATGGGCTTAACCGACGAAGAATACCGGCGAATTGTCGAGTATCTGGGCCGCGAACCAAATGAAGTGGAAC
TGGGCATGTGTGCGGTGATG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKFGVVVFPGSNCDADCFHVLKNVFGRETVYIWHKEDNFDVDCIVLPGGFSYGDYLRAGAIARFSPVMKKVVEFANAGGL
VIGICNGFQILLEAGLLPGAMLRNKSINFRCHDVYLRVENNNTPFTSKAHEGQVLKIPIAHGEGNYYCEPDTLKKLIANG
QVVFRYCNSRGEVTEDANPNGSLYNIAGIINEKGNVLGMMPHPERCSENILGGEDGRVIWESIIAYLERGANRG

Sequences:

>Translated_234_residues
MKFGVVVFPGSNCDADCFHVLKNVFGRETVYIWHKEDNFDVDCIVLPGGFSYGDYLRAGAIARFSPVMKKVVEFANAGGL
VIGICNGFQILLEAGLLPGAMLRNKSINFRCHDVYLRVENNNTPFTSKAHEGQVLKIPIAHGEGNYYCEPDTLKKLIANG
QVVFRYCNSRGEVTEDANPNGSLYNIAGIINEKGNVLGMMPHPERCSENILGGEDGRVIWESIIAYLERGANRG
>Mature_234_residues
MKFGVVVFPGSNCDADCFHVLKNVFGRETVYIWHKEDNFDVDCIVLPGGFSYGDYLRAGAIARFSPVMKKVVEFANAGGL
VIGICNGFQILLEAGLLPGAMLRNKSINFRCHDVYLRVENNNTPFTSKAHEGQVLKIPIAHGEGNYYCEPDTLKKLIANG
QVVFRYCNSRGEVTEDANPNGSLYNIAGIINEKGNVLGMMPHPERCSENILGGEDGRVIWESIIAYLERGANRG

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=200, Percent_Identity=35.5, Blast_Score=84, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17553022, Length=201, Percent_Identity=29.3532338308458, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321498, Length=180, Percent_Identity=36.6666666666667, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582111, Length=184, Percent_Identity=32.6086956521739, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582109, Length=184, Percent_Identity=32.6086956521739, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17137292, Length=184, Percent_Identity=32.6086956521739, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_CARHZ (Q3AD65)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359919.1
- ProteinModelPortal:   Q3AD65
- STRING:   Q3AD65
- GeneID:   3728440
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_1073
- NMPDR:   fig|246194.3.peg.873
- TIGR:   CHY_1073
- eggNOG:   COG0047
- HOGENOM:   HBG302712
- OMA:   FPGTNCD
- ProtClustDB:   PRK03619
- BioCyc:   CHYD246194:CHY_1073-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF07685 GATase_3

EC number: =6.3.5.3

Molecular weight: Translated: 25794; Mature: 25794

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 85-85 ACT_SITE 202-202 ACT_SITE 204-204

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFGVVVFPGSNCDADCFHVLKNVFGRETVYIWHKEDNFDVDCIVLPGGFSYGDYLRAGA
CCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHCC
IARFSPVMKKVVEFANAGGLVIGICNGFQILLEAGLLPGAMLRNKSINFRCHDVYLRVEN
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCHHHHCCCCCEEEEEEEEEEEC
NNTPFTSKAHEGQVLKIPIAHGEGNYYCEPDTLKKLIANGQVVFRYCNSRGEVTEDANPN
CCCCCCCCCCCCCEEEEEEEECCCCEEECHHHHHHHHHCCEEEEEEECCCCCCCCCCCCC
GSLYNIAGIINEKGNVLGMMPHPERCSENILGGEDGRVIWESIIAYLERGANRG
CCEEEEEEEEECCCCEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFGVVVFPGSNCDADCFHVLKNVFGRETVYIWHKEDNFDVDCIVLPGGFSYGDYLRAGA
CCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHCC
IARFSPVMKKVVEFANAGGLVIGICNGFQILLEAGLLPGAMLRNKSINFRCHDVYLRVEN
HHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCHHHHCCCCCEEEEEEEEEEEC
NNTPFTSKAHEGQVLKIPIAHGEGNYYCEPDTLKKLIANGQVVFRYCNSRGEVTEDANPN
CCCCCCCCCCCCCEEEEEEEECCCCEEECHHHHHHHHHCCEEEEEEECCCCCCCCCCCCC
GSLYNIAGIINEKGNVLGMMPHPERCSENILGGEDGRVIWESIIAYLERGANRG
CCEEEEEEEEECCCCEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA