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The map label for this gene is appC [H]

Identifier: 77465263

GI number: 77465263

Start: 315463

End: 316350

Strand: Reverse

Name: appC [H]

Synonym: RSP_3258

Alternate gene names: 77465263

Gene position: 316350-315463 (Counterclockwise)

Preceding gene: 77465264

Following gene: 77465262

Centisome position: 33.55

GC content: 69.71

Gene sequence:

>888_bases
ATGACCGACGCGACCGCGGCTGAGCGCCCCATCCGCGCCAAGGGCGCGCTGCGCCGGCTGGCCGAGCGGCCGCTGGCGCT
CTTCGGCCTGTTCCTGATCCTCCTCGTGGTGGGCGGCGCCGTCCTCGCGCCCCTCGTCGCGCCCTTCGACCCGAGCGAGC
AGCATTTCGACGGGCTGACCATCGAGGGCGCGCCGCTGCCGCCCGGAGGCGCCTTCCTTTTGGGGACCGACCTGCTGGGC
CGCGACCTCTTCTCGCGCATCCTCTGGGGGGCGCGCACCTCGCTCATCATCGGGGTGGCCGCGAACGGGCTTGCGCTTGT
GATCGGCACGCTCGTGGGCCTGACGGCGGGCTATTTCCGCGGCTGGATCGGCGCGGTGCTCATGCGCTTCACCGACCTGA
TGATGGCCTTCCCGGCGCTTCTGCTGGCGATCTGCCTTGCCGCGATCTTCCAGCCCTCGCTCTGGATCGTGGCCATGGTG
ATCGCCTTCGTGAACTGGGTGCAGACCGCGCGGGTGATCTTCACCGAGACCTCGGCCCTGTCCGAACGCGAGTTCATCGC
GGCCGAACGAACCCTGGGCGCGGGCACGGCGCGGATCCTCTTCCGCCACATCCTGCCCCACCTTCTGCCCACCATCATCG
TCTGGGGCACGCTCGGCATCTCGACGACGGTGCTGCTCGAGGCCACGCTCTCCTACCTCGGCGTGGGGGTGCAGCCGCCG
ACGCCCAGCTGGGGCAACATCATCTTCGAGAACCAGACCTACTTCCAGTCGGCGCCCTGGCTCGTCTTCATTCCGGGCGC
GGCCATCCTTCTTCTGGCGCTCGCCTTCAACCTCGTCGGAGACGCGCTGCGCGACGTGCTCGACCCGACCCAGCGCGGGA
GGGACTGA

Upstream 100 bases:

>100_bases
GAGAGCGCCGCCTACGGCCAGCTCCGCCAGATGGCGATGGCCTGGCGGGTGAGTATCGAGGAGGCCGCGCACCGCATCGT
CGCGAGCCAGGGAGGACCGG

Downstream 100 bases:

>100_bases
TGCCCGCCTATCTCCTTCGCCGCCTGTTCCAGTCGGCCCTGATCCTGCTCGGCGTCTCGCTCGTCACCTTCATCCTGCTC
TATGTGCTGCCGGCCGATCC

Product: ABC peptide transporter, inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTDATAAERPIRAKGALRRLAERPLALFGLFLILLVVGGAVLAPLVAPFDPSEQHFDGLTIEGAPLPPGGAFLLGTDLLG
RDLFSRILWGARTSLIIGVAANGLALVIGTLVGLTAGYFRGWIGAVLMRFTDLMMAFPALLLAICLAAIFQPSLWIVAMV
IAFVNWVQTARVIFTETSALSEREFIAAERTLGAGTARILFRHILPHLLPTIIVWGTLGISTTVLLEATLSYLGVGVQPP
TPSWGNIIFENQTYFQSAPWLVFIPGAAILLLALAFNLVGDALRDVLDPTQRGRD

Sequences:

>Translated_295_residues
MTDATAAERPIRAKGALRRLAERPLALFGLFLILLVVGGAVLAPLVAPFDPSEQHFDGLTIEGAPLPPGGAFLLGTDLLG
RDLFSRILWGARTSLIIGVAANGLALVIGTLVGLTAGYFRGWIGAVLMRFTDLMMAFPALLLAICLAAIFQPSLWIVAMV
IAFVNWVQTARVIFTETSALSEREFIAAERTLGAGTARILFRHILPHLLPTIIVWGTLGISTTVLLEATLSYLGVGVQPP
TPSWGNIIFENQTYFQSAPWLVFIPGAAILLLALAFNLVGDALRDVLDPTQRGRD
>Mature_294_residues
TDATAAERPIRAKGALRRLAERPLALFGLFLILLVVGGAVLAPLVAPFDPSEQHFDGLTIEGAPLPPGGAFLLGTDLLGR
DLFSRILWGARTSLIIGVAANGLALVIGTLVGLTAGYFRGWIGAVLMRFTDLMMAFPALLLAICLAAIFQPSLWIVAMVI
AFVNWVQTARVIFTETSALSEREFIAAERTLGAGTARILFRHILPHLLPTIIVWGTLGISTTVLLEATLSYLGVGVQPPT
PSWGNIIFENQTYFQSAPWLVFIPGAAILLLALAFNLVGDALRDVLDPTQRGRD

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=276, Percent_Identity=39.1304347826087, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1789964, Length=254, Percent_Identity=43.7007874015748, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1787760, Length=300, Percent_Identity=34.3333333333333, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1787498, Length=279, Percent_Identity=34.0501792114695, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789889, Length=242, Percent_Identity=36.7768595041322, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787549, Length=296, Percent_Identity=32.7702702702703, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788505, Length=230, Percent_Identity=30.4347826086957, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31651; Mature: 31520

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDATAAERPIRAKGALRRLAERPLALFGLFLILLVVGGAVLAPLVAPFDPSEQHFDGLT
CCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEE
IEGAPLPPGGAFLLGTDLLGRDLFSRILWGARTSLIIGVAANGLALVIGTLVGLTAGYFR
ECCCCCCCCCCEEEHHHHHHHHHHHHHHHHCHHHEEEEECCCHHHHHHHHHHHHHHHHHH
GWIGAVLMRFTDLMMAFPALLLAICLAAIFQPSLWIVAMVIAFVNWVQTARVIFTETSAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
SEREFIAAERTLGAGTARILFRHILPHLLPTIIVWGTLGISTTVLLEATLSYLGVGVQPP
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TPSWGNIIFENQTYFQSAPWLVFIPGAAILLLALAFNLVGDALRDVLDPTQRGRD
CCCCCCEEECCCHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCHHHCCCC
>Mature Secondary Structure 
TDATAAERPIRAKGALRRLAERPLALFGLFLILLVVGGAVLAPLVAPFDPSEQHFDGLT
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEE
IEGAPLPPGGAFLLGTDLLGRDLFSRILWGARTSLIIGVAANGLALVIGTLVGLTAGYFR
ECCCCCCCCCCEEEHHHHHHHHHHHHHHHHCHHHEEEEECCCHHHHHHHHHHHHHHHHHH
GWIGAVLMRFTDLMMAFPALLLAICLAAIFQPSLWIVAMVIAFVNWVQTARVIFTETSAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
SEREFIAAERTLGAGTARILFRHILPHLLPTIIVWGTLGISTTVLLEATLSYLGVGVQPP
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TPSWGNIIFENQTYFQSAPWLVFIPGAAILLLALAFNLVGDALRDVLDPTQRGRD
CCCCCCEEECCCHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]