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The map label for this gene is hbpA [H]

Identifier: 77465261

GI number: 77465261

Start: 312899

End: 314521

Strand: Reverse

Name: hbpA [H]

Synonym: RSP_3255

Alternate gene names: 77465261

Gene position: 314521-312899 (Counterclockwise)

Preceding gene: 77465262

Following gene: 77465260

Centisome position: 33.35

GC content: 65.8

Gene sequence:

>1623_bases
ATGAACAGACTGCTCGCCTCCACCGCCGTGATGCTGGCGCTCGCCCTGCCCGCCGCAGCCCAGGACTATACGCCCGACCC
GAATGCGAAGCCCGGCGGCACGATCACCATCACCTACAAGGACGATGTGGCGACGCTCGATCCGGCCATCGGCTACGACT
GGCAGAACTGGTCGATGATCAAATCGATCTTCGACGGGCTGATGGATTACGTCCCCGGCACGACCGAGCTGCGCCCCGGC
CTCGCCGAGAGCTACGAGATCTCGGAGGACGGGCTCACCTATACGTTCAAGCTGCGCCCGGGCGTGAAATTCCACAACGG
CCGCGAGATGACGGCCGAGGATGTGAAATATTCGCTCGACCGCGTGACCCTGCCTGCGACCCAGTCGCCGGGCGCAGGCT
TCTTCGGCTCGATCAAGGGCTTCGATGCGATGGCCGACGGCTCGGCCAGCACGCTCGAGGGCGTGACGGTGGTCGATCCC
TCGACCGTCAGGATCGAGCTCTCGCGTCCCGACGCCACCTTCCTGCATGTGATGGCGCTGAACTTCGCCTCGGTGGTGCC
GAAGGAAGCCGTCGAGGCGGCGGGCGCGGACTTCGGCAAGCAGCCGGTCGGCACCGGGGCCTTCAAGCTCGCCGAATGGA
CGCTGGGCCAGCGTCTCGTCTTCGAGAAGAACGCCGACTACTGGCGCGAGGGCGTGCCCTATCTCGACAGCATCGTCTTC
GAGGTGGGACAGGAGCCGATCGTGGCGCTGCTGCGGCTGCAGAACGGCGAGGTGGACGTGCCCGGCGACGGCATTCCGCC
TGCGAAATTCACCGAAGTGATGGCCGATCCGGCGCAGGCCGAGCGCGTGGTCGAGGGCGGGCAGCTGCACACGGGCTACA
TCACGATGAACGTGACCCAGCCGCCCTTCGACAATCTGCAGGTCCGTCAGGCCGTCAACATGGCGATCAACAAGCAGCGG
ATCACCCAGATCATCAACGGCCGCGCGATCCCCGCGACCCAGCCGCTGCCGCCCTCGATGCCGGGCTATACCGAAGGCTA
CGAGGGCTATCCGCACGATGTCGAGAAGGCCAAGGCGCTGCTCGCCCAGGCGGGCTTCGCCGACGGGTTCGAGACCGAGC
TCTATGTGATGAACACCGACCCGAACCCACGCATCGCGCAGGCGATCCAGCAGGATCTGTCGCAGATCGGCATCAAGGCC
GCGATCCAGAGCCTCGCGCAGGCCAATGTGATCGAGGCCGGCGGCAATGGCTCGGCGCCGATGATCTGGTCGGGCGGCAT
GGCCTGGATCGCGGATTTCCCCGATCCGTCCAACTTCTACGGCCCGATCCTGGGCTGCGCGGGCGCGGCTGACGGCGGCT
GGAACTGGTCGAAATTTTGCGACGAGGCGCTCGACGCCAAGGCCACCGAGGCCGACAGCCTCGCCGATCCGGCCCGCGCC
GAGGAGCGGCTGAAGCTCTGGTCCGACGTCTATATGGGCGTGATGGAGAAGGCCCCGTGGGTGCCCGTCTTCAACGAACA
GCGCTACACGATGAAATCCGCGCGCATGGGCGGCGACGACAGCCTCTATGTCGATCCCGTCTCGATCCCCGTCAACTACG
ACTATGTCTTCGTGACCGAGTAA

Upstream 100 bases:

>100_bases
GGCCTGCGCCATCGTGCTGGGCAACCTTCTGGCCGATCTCGTGACGCCCTTCATCGACCCCCGCATCAAGCTGAAATAAC
AGGACCGACAGGAGAGACCC

Downstream 100 bases:

>100_bases
GACCCATGTGCAAGGCCTGCAATTACACGATCCACGGCGCGCAGCATCACTTCGGCTGGGACAATTCGCTCCCCCCGGCC
GAGCGTGTGGAGCCCGGCTC

Product: ABC peptide transporter, periplasmic binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MNRLLASTAVMLALALPAAAQDYTPDPNAKPGGTITITYKDDVATLDPAIGYDWQNWSMIKSIFDGLMDYVPGTTELRPG
LAESYEISEDGLTYTFKLRPGVKFHNGREMTAEDVKYSLDRVTLPATQSPGAGFFGSIKGFDAMADGSASTLEGVTVVDP
STVRIELSRPDATFLHVMALNFASVVPKEAVEAAGADFGKQPVGTGAFKLAEWTLGQRLVFEKNADYWREGVPYLDSIVF
EVGQEPIVALLRLQNGEVDVPGDGIPPAKFTEVMADPAQAERVVEGGQLHTGYITMNVTQPPFDNLQVRQAVNMAINKQR
ITQIINGRAIPATQPLPPSMPGYTEGYEGYPHDVEKAKALLAQAGFADGFETELYVMNTDPNPRIAQAIQQDLSQIGIKA
AIQSLAQANVIEAGGNGSAPMIWSGGMAWIADFPDPSNFYGPILGCAGAADGGWNWSKFCDEALDAKATEADSLADPARA
EERLKLWSDVYMGVMEKAPWVPVFNEQRYTMKSARMGGDDSLYVDPVSIPVNYDYVFVTE

Sequences:

>Translated_540_residues
MNRLLASTAVMLALALPAAAQDYTPDPNAKPGGTITITYKDDVATLDPAIGYDWQNWSMIKSIFDGLMDYVPGTTELRPG
LAESYEISEDGLTYTFKLRPGVKFHNGREMTAEDVKYSLDRVTLPATQSPGAGFFGSIKGFDAMADGSASTLEGVTVVDP
STVRIELSRPDATFLHVMALNFASVVPKEAVEAAGADFGKQPVGTGAFKLAEWTLGQRLVFEKNADYWREGVPYLDSIVF
EVGQEPIVALLRLQNGEVDVPGDGIPPAKFTEVMADPAQAERVVEGGQLHTGYITMNVTQPPFDNLQVRQAVNMAINKQR
ITQIINGRAIPATQPLPPSMPGYTEGYEGYPHDVEKAKALLAQAGFADGFETELYVMNTDPNPRIAQAIQQDLSQIGIKA
AIQSLAQANVIEAGGNGSAPMIWSGGMAWIADFPDPSNFYGPILGCAGAADGGWNWSKFCDEALDAKATEADSLADPARA
EERLKLWSDVYMGVMEKAPWVPVFNEQRYTMKSARMGGDDSLYVDPVSIPVNYDYVFVTE
>Mature_540_residues
MNRLLASTAVMLALALPAAAQDYTPDPNAKPGGTITITYKDDVATLDPAIGYDWQNWSMIKSIFDGLMDYVPGTTELRPG
LAESYEISEDGLTYTFKLRPGVKFHNGREMTAEDVKYSLDRVTLPATQSPGAGFFGSIKGFDAMADGSASTLEGVTVVDP
STVRIELSRPDATFLHVMALNFASVVPKEAVEAAGADFGKQPVGTGAFKLAEWTLGQRLVFEKNADYWREGVPYLDSIVF
EVGQEPIVALLRLQNGEVDVPGDGIPPAKFTEVMADPAQAERVVEGGQLHTGYITMNVTQPPFDNLQVRQAVNMAINKQR
ITQIINGRAIPATQPLPPSMPGYTEGYEGYPHDVEKAKALLAQAGFADGFETELYVMNTDPNPRIAQAIQQDLSQIGIKA
AIQSLAQANVIEAGGNGSAPMIWSGGMAWIADFPDPSNFYGPILGCAGAADGGWNWSKFCDEALDAKATEADSLADPARA
EERLKLWSDVYMGVMEKAPWVPVFNEQRYTMKSARMGGDDSLYVDPVSIPVNYDYVFVTE

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=462, Percent_Identity=33.5497835497836, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1787052, Length=498, Percent_Identity=30.5220883534137, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787551, Length=449, Percent_Identity=30.0668151447661, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789397, Length=542, Percent_Identity=25.2767527675277, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1787495, Length=486, Percent_Identity=26.1316872427983, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1787762, Length=450, Percent_Identity=28, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI87081878, Length=490, Percent_Identity=28.3673469387755, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789887, Length=499, Percent_Identity=25.250501002004, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082063, Length=473, Percent_Identity=20.2959830866808, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58467; Mature: 58467

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS00555 ICOSAH_VIR_COAT_S

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLLASTAVMLALALPAAAQDYTPDPNAKPGGTITITYKDDVATLDPAIGYDWQNWSMI
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHH
KSIFDGLMDYVPGTTELRPGLAESYEISEDGLTYTFKLRPGVKFHNGREMTAEDVKYSLD
HHHHHHHHHHCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCEECCCCCCCHHHHHHHHH
RVTLPATQSPGAGFFGSIKGFDAMADGSASTLEGVTVVDPSTVRIELSRPDATFLHVMAL
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHH
NFASVVPKEAVEAAGADFGKQPVGTGAFKLAEWTLGQRLVFEKNADYWREGVPYLDSIVF
HHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCHHHHCCCCHHHHHHH
EVGQEPIVALLRLQNGEVDVPGDGIPPAKFTEVMADPAQAERVVEGGQLHTGYITMNVTQ
HHCCCHHEEHEEECCCCEECCCCCCCCHHHHHHHCCHHHHHHHHCCCEEEEEEEEEEECC
PPFDNLQVRQAVNMAINKQRITQIINGRAIPATQPLPPSMPGYTEGYEGYPHDVEKAKAL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LAQAGFADGFETELYVMNTDPNPRIAQAIQQDLSQIGIKAAIQSLAQANVIEAGGNGSAP
HHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCC
MIWSGGMAWIADFPDPSNFYGPILGCAGAADGGWNWSKFCDEALDAKATEADSLADPARA
EEEECCEEEEECCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCHHHH
EERLKLWSDVYMGVMEKAPWVPVFNEQRYTMKSARMGGDDSLYVDPVSIPVNYDYVFVTE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEEEECCCEEEEEC
>Mature Secondary Structure
MNRLLASTAVMLALALPAAAQDYTPDPNAKPGGTITITYKDDVATLDPAIGYDWQNWSMI
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHH
KSIFDGLMDYVPGTTELRPGLAESYEISEDGLTYTFKLRPGVKFHNGREMTAEDVKYSLD
HHHHHHHHHHCCCCCCCCCCCCCCCEECCCCEEEEEEECCCCEECCCCCCCHHHHHHHHH
RVTLPATQSPGAGFFGSIKGFDAMADGSASTLEGVTVVDPSTVRIELSRPDATFLHVMAL
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHH
NFASVVPKEAVEAAGADFGKQPVGTGAFKLAEWTLGQRLVFEKNADYWREGVPYLDSIVF
HHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCEEEEECCCHHHHCCCCHHHHHHH
EVGQEPIVALLRLQNGEVDVPGDGIPPAKFTEVMADPAQAERVVEGGQLHTGYITMNVTQ
HHCCCHHEEHEEECCCCEECCCCCCCCHHHHHHHCCHHHHHHHHCCCEEEEEEEEEEECC
PPFDNLQVRQAVNMAINKQRITQIINGRAIPATQPLPPSMPGYTEGYEGYPHDVEKAKAL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LAQAGFADGFETELYVMNTDPNPRIAQAIQQDLSQIGIKAAIQSLAQANVIEAGGNGSAP
HHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCC
MIWSGGMAWIADFPDPSNFYGPILGCAGAADGGWNWSKFCDEALDAKATEADSLADPARA
EEEECCEEEEECCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCCHHHH
EERLKLWSDVYMGVMEKAPWVPVFNEQRYTMKSARMGGDDSLYVDPVSIPVNYDYVFVTE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]