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The map label for this gene is hflK [H]

Identifier: 77461888

GI number: 77461888

Start: 6349760

End: 6350818

Strand: Reverse

Name: hflK [H]

Synonym: Pfl01_5668

Alternate gene names: 77461888

Gene position: 6350818-6349760 (Counterclockwise)

Preceding gene: 77461889

Following gene: 77461887

Centisome position: 98.64

GC content: 62.51

Gene sequence:

>1059_bases
ATGAATGAAGTTCCACGTGGAACACATTCGCTGAACAGTCCGTGGATTCAAGCGGGGCGTCTGGCATTCTTTGCCCTTTA
CGCGGTAACCGTTCTGGCGGCATTAGCTTGGGCATTTTCCAATGTCCGGCAGATCGATCCGCAAAACCGCGCGGTGGTTT
TGCATTTCGGAGCGCTGGATCGCATTCAGAATGCCGGCTTGTTGTTGGCCTGGCCGCAGCCGTTCGAACAGGTGGTTTTG
TTGCCGGCGGCTGATCGGGTCATCGAGCGGCGGGTGGAAAATCTGCTGCGCAGTGATCAGGCCGTGCAGGCAGATCGCGT
TGCAACCTTCGCTACGCCGCTGAGCGATGCGCTGGCCGGCTCCGGTTATCTGCTCACCGGTGATGCCGGTGTCGTGCAGC
TGGATGTGCGGGTGTTCTACAAGGTCACCGATCCCTATGACTTCGTACTGCAAGGCGAACATGTGCTGCCGGCGCTGGAT
CGAGTGGTAACGCGCAGCGCAGTCGCACTGACGGCGGCGCGGGATCTGGACACCATTCTGGTGGCGCGGCCGGAGTTGAT
CGGCGCTGACAATCAGGCGGCCGAACGCCGCGAACGGTTGCGCGGTGATCTGGTGCAAGGCATCAACCGACGTCTCGCCG
AGTTGAAGGCGAGCGGGCAGGGCATCGGCATCGAAGTGGCGCGGGTCGATGTGCAATCGAGTCTGCCGGAACCGGCGGTG
AGTGCGTTCAACGCCGTCCTCACTGCCAGCCAGCAAGCCGACAAGGCGGTTGCCAATGCCCGCACCGAGGCCGAGAAACT
TACCCAGTCCGCCAACGAACAGGCCGACCGCACCCTGCAAGTCGCCCACGCCCAGGCCGGTGAGCGCCTGGCCAAGGCCT
CCGCCGACACGGCGACGGTGTTGAGCCTGGCCAAGGCGCAACAGCAGGGTACGGACCCGCAAATGCTGCTGCGTCTGTAC
CGTGAGCGGATGCCGAAGATTCTCGGGCAGGCCGGTTCGGTCACCACGGTCGATCCGAAAGACGATTCCCGCCTGATCAT
TCAGGGAGCCAGTAAATGA

Upstream 100 bases:

>100_bases
TTTCGCCAGACACCAAACTGATCCTGCGCACCGACGCCGCGCCATTCCGGGTGTTGGTCGACGGTCCGCCGAATCTCGAC
AGCAAGAGCGGATTGCAGCC

Downstream 100 bases:

>100_bases
CTGCCACTACCTCAGCTCCGAGCCTGTTGTCCTCGGCCGAACAACGCCGCGCCGCCCGCCAGTTGACCCTGGCGATGCTC
GCCCTCGGCTTGCTTGGTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNEVPRGTHSLNSPWIQAGRLAFFALYAVTVLAALAWAFSNVRQIDPQNRAVVLHFGALDRIQNAGLLLAWPQPFEQVVL
LPAADRVIERRVENLLRSDQAVQADRVATFATPLSDALAGSGYLLTGDAGVVQLDVRVFYKVTDPYDFVLQGEHVLPALD
RVVTRSAVALTAARDLDTILVARPELIGADNQAAERRERLRGDLVQGINRRLAELKASGQGIGIEVARVDVQSSLPEPAV
SAFNAVLTASQQADKAVANARTEAEKLTQSANEQADRTLQVAHAQAGERLAKASADTATVLSLAKAQQQGTDPQMLLRLY
RERMPKILGQAGSVTTVDPKDDSRLIIQGASK

Sequences:

>Translated_352_residues
MNEVPRGTHSLNSPWIQAGRLAFFALYAVTVLAALAWAFSNVRQIDPQNRAVVLHFGALDRIQNAGLLLAWPQPFEQVVL
LPAADRVIERRVENLLRSDQAVQADRVATFATPLSDALAGSGYLLTGDAGVVQLDVRVFYKVTDPYDFVLQGEHVLPALD
RVVTRSAVALTAARDLDTILVARPELIGADNQAAERRERLRGDLVQGINRRLAELKASGQGIGIEVARVDVQSSLPEPAV
SAFNAVLTASQQADKAVANARTEAEKLTQSANEQADRTLQVAHAQAGERLAKASADTATVLSLAKAQQQGTDPQMLLRLY
RERMPKILGQAGSVTTVDPKDDSRLIIQGASK
>Mature_352_residues
MNEVPRGTHSLNSPWIQAGRLAFFALYAVTVLAALAWAFSNVRQIDPQNRAVVLHFGALDRIQNAGLLLAWPQPFEQVVL
LPAADRVIERRVENLLRSDQAVQADRVATFATPLSDALAGSGYLLTGDAGVVQLDVRVFYKVTDPYDFVLQGEHVLPALD
RVVTRSAVALTAARDLDTILVARPELIGADNQAAERRERLRGDLVQGINRRLAELKASGQGIGIEVARVDVQSSLPEPAV
SAFNAVLTASQQADKAVANARTEAEKLTQSANEQADRTLQVAHAQAGERLAKASADTATVLSLAKAQQQGTDPQMLLRLY
RERMPKILGQAGSVTTVDPKDDSRLIIQGASK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 38018; Mature: 38018

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVPRGTHSLNSPWIQAGRLAFFALYAVTVLAALAWAFSNVRQIDPQNRAVVLHFGALD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHH
RIQNAGLLLAWPQPFEQVVLLPAADRVIERRVENLLRSDQAVQADRVATFATPLSDALAG
HHCCCCEEEECCCCHHHEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCC
SGYLLTGDAGVVQLDVRVFYKVTDPYDFVLQGEHVLPALDRVVTRSAVALTAARDLDTIL
CCEEEECCCCEEEEEEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHHE
VARPELIGADNQAAERRERLRGDLVQGINRRLAELKASGQGIGIEVARVDVQSSLPEPAV
EECCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHCCCCHHH
SAFNAVLTASQQADKAVANARTEAEKLTQSANEQADRTLQVAHAQAGERLAKASADTATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LSLAKAQQQGTDPQMLLRLYRERMPKILGQAGSVTTVDPKDDSRLIIQGASK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCC
>Mature Secondary Structure
MNEVPRGTHSLNSPWIQAGRLAFFALYAVTVLAALAWAFSNVRQIDPQNRAVVLHFGALD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHH
RIQNAGLLLAWPQPFEQVVLLPAADRVIERRVENLLRSDQAVQADRVATFATPLSDALAG
HHCCCCEEEECCCCHHHEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCC
SGYLLTGDAGVVQLDVRVFYKVTDPYDFVLQGEHVLPALDRVVTRSAVALTAARDLDTIL
CCEEEECCCCEEEEEEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHHE
VARPELIGADNQAAERRERLRGDLVQGINRRLAELKASGQGIGIEVARVDVQSSLPEPAV
EECCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEHHHCCCCHHH
SAFNAVLTASQQADKAVANARTEAEKLTQSANEQADRTLQVAHAQAGERLAKASADTATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LSLAKAQQQGTDPQMLLRLYRERMPKILGQAGSVTTVDPKDDSRLIIQGASK
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]