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The map label for this gene is hflC [H]

Identifier: 77461889

GI number: 77461889

Start: 6350815

End: 6351861

Strand: Reverse

Name: hflC [H]

Synonym: Pfl01_5669

Alternate gene names: 77461889

Gene position: 6351861-6350815 (Counterclockwise)

Preceding gene: 77461890

Following gene: 77461888

Centisome position: 98.66

GC content: 63.8

Gene sequence:

>1047_bases
TTGAGCCAGTCGCACACTCACGATCACCATGACCACAGCGGCCACGATCATGCTCATGGCAGCGGTCATCACCATCACGG
GCATCATCACCATCACCACGGTGCGCCGGAAGACGCGGGGCCTTTTCCGTGGAAACGCATGGGCTGGGCGGGATTGCTGG
TGGCGTTCGCCATCGCGGCGGCGAGCCTGGTGCAAGTGCGCTCCGGTGAAGCCACGGTCATCACCCGGTTCGGCAACCCG
TCCCGCGTGTTGCTGGAACCGGGGCTGAGCTGGCGTTGGCCGGCGCCGTTCGAAGCAGCGATTCCGGTGGACCTGCGTTT
GCGCACGACCTCCAGCGGCTTGCAGGATGTCGGCACCCGCGACGGTCTGCGCATCATCGTGCAGGCGTACGTGGCCTGGC
AGGTGCAGGGCGATCCCGACAACGTGCAGCGCTTCATGCGCGCGGTGCAGAACCAGCCGGACGAAGCGGCGCGGCAGATT
CGCACGTTTGTCGGCTCGGCACTGGAAACCACGGCCAGCAGTTTTGATCTGGCCAATCTGGTCAATACCGATGCCAGTCA
GGTTCGAATCGCCGATTTTGAAGCGCAGTTGCGTCAGCAAATCGATCAGCAACTGCTCGCGACTTACGGCGTGCGCGTGG
TGCAGGTGGGCATCGAACGGCTGACCTTGCCATCGGTGACCCTGACCGCAACGGTCGACCGGATGCGCGCCGAGCGTGAA
ACCATCGCCACCGAACGCACCGCCATTGGCAAACGTGAAGCAGCGCAAATCCGCTCCGCCGCCGAACGCGATGCGCGCAT
CGTGCAAGCCGATGCCACGGTGAAAGCCGCCGATATCGAAGCCCAATCGCGAGTGGAAGCGGCGCAGATTTATGGGCGTG
CTTACGGCGGTTCGCCGCAGCTGTACAACTTGCTGCGCTCGCTGGACACCCTCGGCACTATCGTTTCGCCAGACACCAAA
CTGATCCTGCGCACCGACGCCGCGCCATTCCGGGTGTTGGTCGACGGTCCGCCGAATCTCGACAGCAAGAGCGGATTGCA
GCCATGA

Upstream 100 bases:

>100_bases
ATCGTCTGGGCGGCAGCAGTAACGCACCGACCATCGACCTGCGTACGTTCACGCTGCCGGCAGATCCGGCGCGCACCACC
GCTCAGCCAGGAGCCAGCCA

Downstream 100 bases:

>100_bases
ATGAAGTTCCACGTGGAACACATTCGCTGAACAGTCCGTGGATTCAAGCGGGGCGTCTGGCATTCTTTGCCCTTTACGCG
GTAACCGTTCTGGCGGCATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSQSHTHDHHDHSGHDHAHGSGHHHHGHHHHHHGAPEDAGPFPWKRMGWAGLLVAFAIAAASLVQVRSGEATVITRFGNP
SRVLLEPGLSWRWPAPFEAAIPVDLRLRTTSSGLQDVGTRDGLRIIVQAYVAWQVQGDPDNVQRFMRAVQNQPDEAARQI
RTFVGSALETTASSFDLANLVNTDASQVRIADFEAQLRQQIDQQLLATYGVRVVQVGIERLTLPSVTLTATVDRMRAERE
TIATERTAIGKREAAQIRSAAERDARIVQADATVKAADIEAQSRVEAAQIYGRAYGGSPQLYNLLRSLDTLGTIVSPDTK
LILRTDAAPFRVLVDGPPNLDSKSGLQP

Sequences:

>Translated_348_residues
MSQSHTHDHHDHSGHDHAHGSGHHHHGHHHHHHGAPEDAGPFPWKRMGWAGLLVAFAIAAASLVQVRSGEATVITRFGNP
SRVLLEPGLSWRWPAPFEAAIPVDLRLRTTSSGLQDVGTRDGLRIIVQAYVAWQVQGDPDNVQRFMRAVQNQPDEAARQI
RTFVGSALETTASSFDLANLVNTDASQVRIADFEAQLRQQIDQQLLATYGVRVVQVGIERLTLPSVTLTATVDRMRAERE
TIATERTAIGKREAAQIRSAAERDARIVQADATVKAADIEAQSRVEAAQIYGRAYGGSPQLYNLLRSLDTLGTIVSPDTK
LILRTDAAPFRVLVDGPPNLDSKSGLQP
>Mature_347_residues
SQSHTHDHHDHSGHDHAHGSGHHHHGHHHHHHGAPEDAGPFPWKRMGWAGLLVAFAIAAASLVQVRSGEATVITRFGNPS
RVLLEPGLSWRWPAPFEAAIPVDLRLRTTSSGLQDVGTRDGLRIIVQAYVAWQVQGDPDNVQRFMRAVQNQPDEAARQIR
TFVGSALETTASSFDLANLVNTDASQVRIADFEAQLRQQIDQQLLATYGVRVVQVGIERLTLPSVTLTATVDRMRAERET
IATERTAIGKREAAQIRSAAERDARIVQADATVKAADIEAQSRVEAAQIYGRAYGGSPQLYNLLRSLDTLGTIVSPDTKL
ILRTDAAPFRVLVDGPPNLDSKSGLQP

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=134, Percent_Identity=28.3582089552239, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38067; Mature: 37936

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSHTHDHHDHSGHDHAHGSGHHHHGHHHHHHGAPEDAGPFPWKRMGWAGLLVAFAIAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ASLVQVRSGEATVITRFGNPSRVLLEPGLSWRWPAPFEAAIPVDLRLRTTSSGLQDVGTR
HHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCC
DGLRIIVQAYVAWQVQGDPDNVQRFMRAVQNQPDEAARQIRTFVGSALETTASSFDLANL
CHHHHHEEEHHEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNTDASQVRIADFEAQLRQQIDQQLLATYGVRVVQVGIERLTLPSVTLTATVDRMRAERE
HCCCCHHEEEHHHHHHHHHHHHHHHHHHHCHHHEEHHHHHHCCCCEEEHHHHHHHHHHHH
TIATERTAIGKREAAQIRSAAERDARIVQADATVKAADIEAQSRVEAAQIYGRAYGGSPQ
HHHHHHHHHCHHHHHHHHHHHHHCCEEEEECCEEEEECCCHHHHHHHHHHHHHHCCCCHH
LYNLLRSLDTLGTIVSPDTKLILRTDAAPFRVLVDGPPNLDSKSGLQP
HHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SQSHTHDHHDHSGHDHAHGSGHHHHGHHHHHHGAPEDAGPFPWKRMGWAGLLVAFAIAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ASLVQVRSGEATVITRFGNPSRVLLEPGLSWRWPAPFEAAIPVDLRLRTTSSGLQDVGTR
HHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCC
DGLRIIVQAYVAWQVQGDPDNVQRFMRAVQNQPDEAARQIRTFVGSALETTASSFDLANL
CHHHHHEEEHHEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNTDASQVRIADFEAQLRQQIDQQLLATYGVRVVQVGIERLTLPSVTLTATVDRMRAERE
HCCCCHHEEEHHHHHHHHHHHHHHHHHHHCHHHEEHHHHHHCCCCEEEHHHHHHHHHHHH
TIATERTAIGKREAAQIRSAAERDARIVQADATVKAADIEAQSRVEAAQIYGRAYGGSPQ
HHHHHHHHHCHHHHHHHHHHHHHCCEEEEECCEEEEECCCHHHHHHHHHHHHHHCCCCHH
LYNLLRSLDTLGTIVSPDTKLILRTDAAPFRVLVDGPPNLDSKSGLQP
HHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]