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The map label for this gene is ybaL [H]

Identifier: 77461868

GI number: 77461868

Start: 6330057

End: 6331820

Strand: Reverse

Name: ybaL [H]

Synonym: Pfl01_5648

Alternate gene names: 77461868

Gene position: 6331820-6330057 (Counterclockwise)

Preceding gene: 77461870

Following gene: 77461863

Centisome position: 98.34

GC content: 60.77

Gene sequence:

>1764_bases
ATGCATGCCATCAGCTTTATTCAGGATCTGGCGGTGATCATGTTGGTCGCAGGTGTGGTGACCGTGCTGTTCCACCGCTT
CAAGCAGCCGGTGGTGCTCGGTTACATCGTCGCCGGCTTCATCATCGGCCCGCACACACCGCCGTTCGGCCTGATCCACG
ACGAAGAAACCATCAAGACCCTCGCCGAGCTGGGGGTGATTTTCCTGATGTTCTGCCTGGGCCTGGAGTTCAGCCTGCGC
AAGCTGTTCAAGGTCGGCGCCACGGCCTTCATCGCGGCGTTCCTGGAAATTGTCCTGATGATCTGGATCGGCTACGAAAT
CGGCCGCTGGTTCGACTGGAACACCATGGATTCGCTGTTCCTCGGCGCGATCCTGGCGATTTCCTCGACCACCATCATCG
TCAAGGCGCTCAACGACCTGAAGATGAAAAACGAGCGCTTCGCGCAGCTGATCTTCGGCGTGCTGATCGTCGAGGATATT
CTTGGCATCGGCATCATCGCCTTGCTGTCGAGCATTGCGGTCAGCGGCACGGTGAGCTCCGGCGAAGTGTTTTCCACGGT
CGGCAAGCTCTCGCTGTTCATGATCGTCGCCCTGGTAGTCGGCATTCTGCTGGTGCCGCGTCTGTTGGCTTACGTCGCCA
GGTTCGAAAGCAACGAGATGCTGCTGATCACCGTGCTGGGCCTGTGTTTCGGTTTCTGCCTGCTGGTGGTCAAACTCGAG
TACAGCATGGTGCTCGGGGCGTTCCTGATCGGCGCGATCATGGCCGAGTCGCGGCAACTGCTGAAAATCGAGCGCCTGAT
CGAGCCGGTTCGCGACCTGTTCAGTGCGATCTTCTTCGTCGCCATCGGCCTGATGCTCGATCCGATGATCCTTCTGCAAT
ACGCGTGGCCAATTGCGGTAATCACTGTCGCCGTGGTGCTGGGCAAGATGCTGTCCTGCGGCCTCGGTGCCTTTATCGCC
GGTAATGACGGACGCACCTCACTGCGGGTCGGGATGGGGCTTTCGCAGATTGGTGAATTCTCCTTCATCATCGCGGCGCT
GGGGATGACCCTGCAGGTCACCAGCAACTTCCTGTATCCGGTGGCCGTGGCGGTTTCGGTGATTACCACGTTGCTGACGC
CGTACCTGATCCGGGCTGCCGATCCGCTGTCGATCAAGCTGTCAGCCGCGATGCCGCAGCGCCTCGGTCGAGTGTTCGGA
ATGTACGGCGAATGGCTGCGTAGCATTCAGCCGCAGGGTGAGGGCGCGATGCTGGCGTCGATGATCCGGCGGATCCTGCT
GCAGGTCGGGGTCAATCTGGCGCTGGTGATCGCGATCTTCTTTGCCGGCGCTTTCTTTGCCGGGCGCCTCTCGATCTGGA
TGCAGGAATGGATCAGCGACCCAAGCTGGCAGAAGGCGTTGATCTGGGGCGGGGCGTTGCTGGTGTCGTTGCCGTTCCTG
ATCGCGGCCTATCGCAAGCTCAAGGCGCTGTCGATGTTGCTGGCGGAGATGGGTGTGAAGCCGGAAATGGCCGGGCGTCA
CACACAGCGAGTGCGCCGAGTGATCGCCGAAGTGATCCCGATCATCTCGCTGCTGGTGATTTTCCTGCTGTTGGCAGCCT
TGTCGGCCAGTATCTTGCCGACCAACAAGTTGCTGGTGCTGATCGCCGTGGTCGCGGCCGCCGTGGCGGCGCTGCTCTGG
CGCTGGTTCATCCGGGTGCACACGCGGATGCAGGTGGCCCTGCTGGAAACCCTCGACAACCACAAGGAGTCGTCGGGGCA
CTGA

Upstream 100 bases:

>100_bases
CTCCCCAAGGGCGATTCCTACACCCAAAGCGGATTTTTACTCAGCTCGCCCAGACATTTCCCATGCCTGCGTGAGCCTCG
TCATTCAAGGAGCCCACACC

Downstream 100 bases:

>100_bases
CCACCCATCAAGGCGGGCGTGTCAGCTTTCCAGCCAGACGTCCCGCGCCCAGTGCCAGACCGATTCCCAGGACTCTTCGG
TGATCAGTTCTTCTTCGCCC

Product: Sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MHAISFIQDLAVIMLVAGVVTVLFHRFKQPVVLGYIVAGFIIGPHTPPFGLIHDEETIKTLAELGVIFLMFCLGLEFSLR
KLFKVGATAFIAAFLEIVLMIWIGYEIGRWFDWNTMDSLFLGAILAISSTTIIVKALNDLKMKNERFAQLIFGVLIVEDI
LGIGIIALLSSIAVSGTVSSGEVFSTVGKLSLFMIVALVVGILLVPRLLAYVARFESNEMLLITVLGLCFGFCLLVVKLE
YSMVLGAFLIGAIMAESRQLLKIERLIEPVRDLFSAIFFVAIGLMLDPMILLQYAWPIAVITVAVVLGKMLSCGLGAFIA
GNDGRTSLRVGMGLSQIGEFSFIIAALGMTLQVTSNFLYPVAVAVSVITTLLTPYLIRAADPLSIKLSAAMPQRLGRVFG
MYGEWLRSIQPQGEGAMLASMIRRILLQVGVNLALVIAIFFAGAFFAGRLSIWMQEWISDPSWQKALIWGGALLVSLPFL
IAAYRKLKALSMLLAEMGVKPEMAGRHTQRVRRVIAEVIPIISLLVIFLLLAALSASILPTNKLLVLIAVVAAAVAALLW
RWFIRVHTRMQVALLETLDNHKESSGH

Sequences:

>Translated_587_residues
MHAISFIQDLAVIMLVAGVVTVLFHRFKQPVVLGYIVAGFIIGPHTPPFGLIHDEETIKTLAELGVIFLMFCLGLEFSLR
KLFKVGATAFIAAFLEIVLMIWIGYEIGRWFDWNTMDSLFLGAILAISSTTIIVKALNDLKMKNERFAQLIFGVLIVEDI
LGIGIIALLSSIAVSGTVSSGEVFSTVGKLSLFMIVALVVGILLVPRLLAYVARFESNEMLLITVLGLCFGFCLLVVKLE
YSMVLGAFLIGAIMAESRQLLKIERLIEPVRDLFSAIFFVAIGLMLDPMILLQYAWPIAVITVAVVLGKMLSCGLGAFIA
GNDGRTSLRVGMGLSQIGEFSFIIAALGMTLQVTSNFLYPVAVAVSVITTLLTPYLIRAADPLSIKLSAAMPQRLGRVFG
MYGEWLRSIQPQGEGAMLASMIRRILLQVGVNLALVIAIFFAGAFFAGRLSIWMQEWISDPSWQKALIWGGALLVSLPFL
IAAYRKLKALSMLLAEMGVKPEMAGRHTQRVRRVIAEVIPIISLLVIFLLLAALSASILPTNKLLVLIAVVAAAVAALLW
RWFIRVHTRMQVALLETLDNHKESSGH
>Mature_587_residues
MHAISFIQDLAVIMLVAGVVTVLFHRFKQPVVLGYIVAGFIIGPHTPPFGLIHDEETIKTLAELGVIFLMFCLGLEFSLR
KLFKVGATAFIAAFLEIVLMIWIGYEIGRWFDWNTMDSLFLGAILAISSTTIIVKALNDLKMKNERFAQLIFGVLIVEDI
LGIGIIALLSSIAVSGTVSSGEVFSTVGKLSLFMIVALVVGILLVPRLLAYVARFESNEMLLITVLGLCFGFCLLVVKLE
YSMVLGAFLIGAIMAESRQLLKIERLIEPVRDLFSAIFFVAIGLMLDPMILLQYAWPIAVITVAVVLGKMLSCGLGAFIA
GNDGRTSLRVGMGLSQIGEFSFIIAALGMTLQVTSNFLYPVAVAVSVITTLLTPYLIRAADPLSIKLSAAMPQRLGRVFG
MYGEWLRSIQPQGEGAMLASMIRRILLQVGVNLALVIAIFFAGAFFAGRLSIWMQEWISDPSWQKALIWGGALLVSLPFL
IAAYRKLKALSMLLAEMGVKPEMAGRHTQRVRRVIAEVIPIISLLVIFLLLAALSASILPTNKLLVLIAVVAAAVAALLW
RWFIRVHTRMQVALLETLDNHKESSGH

Specific function: Unknown

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=412, Percent_Identity=28.3980582524272, Blast_Score=100, Evalue=5e-21,
Organism=Escherichia coli, GI1786685, Length=387, Percent_Identity=33.5917312661499, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1786232, Length=276, Percent_Identity=30.7971014492754, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1789749, Length=372, Percent_Identity=27.6881720430108, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 64179; Mature: 64179

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAISFIQDLAVIMLVAGVVTVLFHRFKQPVVLGYIVAGFIIGPHTPPFGLIHDEETIKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
LAELGVIFLMFCLGLEFSLRKLFKVGATAFIAAFLEIVLMIWIGYEIGRWFDWNTMDSLF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
LGAILAISSTTIIVKALNDLKMKNERFAQLIFGVLIVEDILGIGIIALLSSIAVSGTVSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GEVFSTVGKLSLFMIVALVVGILLVPRLLAYVARFESNEMLLITVLGLCFGFCLLVVKLE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
YSMVLGAFLIGAIMAESRQLLKIERLIEPVRDLFSAIFFVAIGLMLDPMILLQYAWPIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITVAVVLGKMLSCGLGAFIAGNDGRTSLRVGMGLSQIGEFSFIIAALGMTLQVTSNFLYP
HHHHHHHHHHHHCCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVAVSVITTLLTPYLIRAADPLSIKLSAAMPQRLGRVFGMYGEWLRSIQPQGEGAMLAS
HHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
MIRRILLQVGVNLALVIAIFFAGAFFAGRLSIWMQEWISDPSWQKALIWGGALLVSLPFL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
IAAYRKLKALSMLLAEMGVKPEMAGRHTQRVRRVIAEVIPIISLLVIFLLLAALSASILP
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TNKLLVLIAVVAAAVAALLWRWFIRVHTRMQVALLETLDNHKESSGH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]