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The map label for this gene is pdxY [H]

Identifier: 77461870

GI number: 77461870

Start: 6332629

End: 6333501

Strand: Reverse

Name: pdxY [H]

Synonym: Pfl01_5650

Alternate gene names: 77461870

Gene position: 6333501-6332629 (Counterclockwise)

Preceding gene: 77461872

Following gene: 77461868

Centisome position: 98.37

GC content: 63.12

Gene sequence:

>873_bases
ATGAAACGTACGCCTCATCTGCTCGCCATCCAGTCCCATGTGGTGTTCGGCCACGCCGGCAACAGCGCTGCGGTTTTTCC
GATGCAGCGGGTCGGGGTGAATGTCTGGCCGCTCAATACGGTGCAGTTTTCCAACCATACGCAGTACGGTCAGTGGGCCG
GCGAAGTGCTGGCGCCGCACCGGATCCCCGAACTGGTCGAAGGCATTGCCGCCATCGGTGAGCTCGGTAATTGCGATGCG
GTGCTGTCAGGTTATCTCGGTAGCGCGGCGCAGGGCCGGGCGATTCTCAGTGGCATCGAGCGGATCAAGGCGGTCAACCC
GAAAGCCCTTTATCTGTGCGACCCGGTGATGGGGCATCCGGAAAAGGGTTGCAGCGTTCCCGCCGAGGTCAGTGACTTCC
TGCTGGAAGAAGCCGCTGCCGTTGCGGATTTCATGTGCCCGAACCAGTTGGAGCTGGACAGCTTCTCCGGGCGTAAGCCG
CAGTCGCTGTTCGATTGCCTGGCGATGGCGCGGGCGCTGCTGGCGCGTGGGCCGAAAGCGGTGCTGGTCAAACATCTGGA
TTATCCGGGCAAACCGGCGGATGGCTTTGAAATGTTGCTGGTAACGGCCGAGGGCAGCTGGCATCTGCGGCGTCCGCTGC
TGGCGTTTCCGCGTCAGCCGGTCGGTGTGGGCGATCTGACGTCCGGCCTGTTCCTGGCGAGAGTGCTGCTCGGTGACAAC
CTGGTGGCGGCGTTTGAATTCACCGCAGCAGCGGTGCATGAAGTGCTGCTGGAAACCCAGGCCTGCGCCAGTTACGAGCT
GCAGCTGGTGCGAGCGCAGGACCGGATTGCGCACCCGCGGGTGAAGTTCGAGGCTACGCCGATCAGCCTCTGA

Upstream 100 bases:

>100_bases
TGATGGCGTCAGCTTAACTGCGTCGCCGGTCTGTCGTACAGGCTGCTTTTCGTCGCATACTGCGCGGCTTGAATTTCAAT
CGTTTTACGGAAAAACCCGA

Downstream 100 bases:

>100_bases
TCATTGCAGCGCTCGCGGACCACGTCCGCGAGCGTGCTTTCACTCAGGCGTCGCCCTTGATTTCCTGATAGCGCTTTTCC
AGCTCCTGACGGATCTGCCG

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKRTPHLLAIQSHVVFGHAGNSAAVFPMQRVGVNVWPLNTVQFSNHTQYGQWAGEVLAPHRIPELVEGIAAIGELGNCDA
VLSGYLGSAAQGRAILSGIERIKAVNPKALYLCDPVMGHPEKGCSVPAEVSDFLLEEAAAVADFMCPNQLELDSFSGRKP
QSLFDCLAMARALLARGPKAVLVKHLDYPGKPADGFEMLLVTAEGSWHLRRPLLAFPRQPVGVGDLTSGLFLARVLLGDN
LVAAFEFTAAAVHEVLLETQACASYELQLVRAQDRIAHPRVKFEATPISL

Sequences:

>Translated_290_residues
MKRTPHLLAIQSHVVFGHAGNSAAVFPMQRVGVNVWPLNTVQFSNHTQYGQWAGEVLAPHRIPELVEGIAAIGELGNCDA
VLSGYLGSAAQGRAILSGIERIKAVNPKALYLCDPVMGHPEKGCSVPAEVSDFLLEEAAAVADFMCPNQLELDSFSGRKP
QSLFDCLAMARALLARGPKAVLVKHLDYPGKPADGFEMLLVTAEGSWHLRRPLLAFPRQPVGVGDLTSGLFLARVLLGDN
LVAAFEFTAAAVHEVLLETQACASYELQLVRAQDRIAHPRVKFEATPISL
>Mature_290_residues
MKRTPHLLAIQSHVVFGHAGNSAAVFPMQRVGVNVWPLNTVQFSNHTQYGQWAGEVLAPHRIPELVEGIAAIGELGNCDA
VLSGYLGSAAQGRAILSGIERIKAVNPKALYLCDPVMGHPEKGCSVPAEVSDFLLEEAAAVADFMCPNQLELDSFSGRKP
QSLFDCLAMARALLARGPKAVLVKHLDYPGKPADGFEMLLVTAEGSWHLRRPLLAFPRQPVGVGDLTSGLFLARVLLGDN
LVAAFEFTAAAVHEVLLETQACASYELQLVRAQDRIAHPRVKFEATPISL

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=311, Percent_Identity=31.5112540192926, Blast_Score=152, Evalue=5e-37,
Organism=Escherichia coli, GI1787924, Length=284, Percent_Identity=55.9859154929578, Blast_Score=321, Evalue=5e-89,
Organism=Escherichia coli, GI1788758, Length=263, Percent_Identity=26.615969581749, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17507759, Length=292, Percent_Identity=30.4794520547945, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17507757, Length=302, Percent_Identity=29.8013245033113, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6320806, Length=240, Percent_Identity=32.5, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324354, Length=186, Percent_Identity=31.1827956989247, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI45553007, Length=296, Percent_Identity=31.0810810810811, Blast_Score=128, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31247; Mature: 31247

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTPHLLAIQSHVVFGHAGNSAAVFPMQRVGVNVWPLNTVQFSNHTQYGQWAGEVLAPH
CCCCCCEEEEEEEEEEEECCCCEEECCHHHHCCEEECCCEEEECCCCCCHHHHHHHCCCC
RIPELVEGIAAIGELGNCDAVLSGYLGSAAQGRAILSGIERIKAVNPKALYLCDPVMGHP
CHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCC
EKGCSVPAEVSDFLLEEAAAVADFMCPNQLELDSFSGRKPQSLFDCLAMARALLARGPKA
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHH
VLVKHLDYPGKPADGFEMLLVTAEGSWHLRRPLLAFPRQPVGVGDLTSGLFLARVLLGDN
HHHEECCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCC
LVAAFEFTAAAVHEVLLETQACASYELQLVRAQDRIAHPRVKFEATPISL
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHCCCCEEEECCCCCC
>Mature Secondary Structure
MKRTPHLLAIQSHVVFGHAGNSAAVFPMQRVGVNVWPLNTVQFSNHTQYGQWAGEVLAPH
CCCCCCEEEEEEEEEEEECCCCEEECCHHHHCCEEECCCEEEECCCCCCHHHHHHHCCCC
RIPELVEGIAAIGELGNCDAVLSGYLGSAAQGRAILSGIERIKAVNPKALYLCDPVMGHP
CHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCC
EKGCSVPAEVSDFLLEEAAAVADFMCPNQLELDSFSGRKPQSLFDCLAMARALLARGPKA
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHH
VLVKHLDYPGKPADGFEMLLVTAEGSWHLRRPLLAFPRQPVGVGDLTSGLFLARVLLGDN
HHHEECCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCC
LVAAFEFTAAAVHEVLLETQACASYELQLVRAQDRIAHPRVKFEATPISL
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA