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The map label for this gene is algR [H]

Identifier: 77461709

GI number: 77461709

Start: 6155728

End: 6156474

Strand: Reverse

Name: algR [H]

Synonym: Pfl01_5488

Alternate gene names: 77461709

Gene position: 6156474-6155728 (Counterclockwise)

Preceding gene: 77461711

Following gene: 77461708

Centisome position: 95.62

GC content: 63.19

Gene sequence:

>747_bases
ATGAATGTCCTGATCGTTGATGACGAACCACTGGCCCGCGAGCGACTCAGCCGAATGGTGAGCGAGCTCGAGGGGTACAC
AGTCCTGGAGCCCAGCGCCACCAATGGCGAAGAGGCGTTGGCACTGATCGACAGCCACAAGCCGGATATCGTACTGCTCG
ATATCCGCATGCCGGGCCTCGATGGCCTGCAGGTGGCTGCCCGTCTGTGCGAACGCGAAACCCCGCCGGCCGTGGTGTTT
TGCGCAGGTCCCGATGAATTTGCCGTGGAAGCCCTGCAGGCCAGCGCCGTGGGCTATGTGGTGAAACCCGTGCGAACCGA
ACATCTGCATGACGCCCTGAAACGGGCTGAACGTCCCAACCGGGCCCAGCTCTCGGCCCTGACCCGTCCTGCCGCCGAAA
GCGGTAACGGCCCGCGCAGCCACATCAGCGCCCGCACCCGCAAAGGCATCGAACTGATTCCGCTGGATCAGGTGGTGTAC
TTCATTGCCGACCACAAATACGTGACATTGCGCCACGAAGCTGGCGAAGTCCTTCTGGATGAGCCGCTCAAGGCGCTGGA
AGACGAATTCGGCGAGCGCTTCGTGCGGATCCACCGCAACGCGCTGGTCGCCCGCGACCGCATCGAGCGTCTGCAACGTA
CACCGCTGGGCCACTTCCAGTTGTTCCTCAAGGGCCTCAACGGTGACGCGCTGATCGTCAGCCGCCGGCATGTGGCGGGC
GTGCGCAAAATGATGCAGGGGCTTTAG

Upstream 100 bases:

>100_bases
TTGGCGCTCGCGCTAGTCTTAGCGTGGATCGCGGTGACGGACGTCACTCCACTTGTCTACGCTATCCTTGTGCGAGACTC
ACGCAGGAATCCAGCGCAAT

Downstream 100 bases:

>100_bases
TCCGCAGGCTCCGGGCGGTTCTTCGTTCTTTTCACCAGGCATTGCAGGCCAGGGAGGCCACGCCGTTTCTGATTCAGGTC
AAAGTGGATTTGGCTGAGCT

Product: two-component response regulator AlgR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNVLIVDDEPLARERLSRMVSELEGYTVLEPSATNGEEALALIDSHKPDIVLLDIRMPGLDGLQVAARLCERETPPAVVF
CAGPDEFAVEALQASAVGYVVKPVRTEHLHDALKRAERPNRAQLSALTRPAAESGNGPRSHISARTRKGIELIPLDQVVY
FIADHKYVTLRHEAGEVLLDEPLKALEDEFGERFVRIHRNALVARDRIERLQRTPLGHFQLFLKGLNGDALIVSRRHVAG
VRKMMQGL

Sequences:

>Translated_248_residues
MNVLIVDDEPLARERLSRMVSELEGYTVLEPSATNGEEALALIDSHKPDIVLLDIRMPGLDGLQVAARLCERETPPAVVF
CAGPDEFAVEALQASAVGYVVKPVRTEHLHDALKRAERPNRAQLSALTRPAAESGNGPRSHISARTRKGIELIPLDQVVY
FIADHKYVTLRHEAGEVLLDEPLKALEDEFGERFVRIHRNALVARDRIERLQRTPLGHFQLFLKGLNGDALIVSRRHVAG
VRKMMQGL
>Mature_248_residues
MNVLIVDDEPLARERLSRMVSELEGYTVLEPSATNGEEALALIDSHKPDIVLLDIRMPGLDGLQVAARLCERETPPAVVF
CAGPDEFAVEALQASAVGYVVKPVRTEHLHDALKRAERPNRAQLSALTRPAAESGNGPRSHISARTRKGIELIPLDQVVY
FIADHKYVTLRHEAGEVLLDEPLKALEDEFGERFVRIHRNALVARDRIERLQRTPLGHFQLFLKGLNGDALIVSRRHVAG
VRKMMQGL

Specific function: Positive regulator of the algD gene, which codes for a GDP-mannose dehydrogenase, a key step enzyme in the alginate biosynthesis pathway [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=245, Percent_Identity=28.9795918367347, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788724, Length=252, Percent_Identity=27.3809523809524, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=39.6551724137931, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788222, Length=173, Percent_Identity=26.0115606936416, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27608; Mature: 27608

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLIVDDEPLARERLSRMVSELEGYTVLEPSATNGEEALALIDSHKPDIVLLDIRMPGL
CEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHHEEEEECCCCCEEEEEEECCCC
DGLQVAARLCERETPPAVVFCAGPDEFAVEALQASAVGYVVKPVRTEHLHDALKRAERPN
CHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
RAQLSALTRPAAESGNGPRSHISARTRKGIELIPLDQVVYFIADHKYVTLRHEAGEVLLD
HHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHEECCEEEEEECCCCCHHHH
EPLKALEDEFGERFVRIHRNALVARDRIERLQRTPLGHFQLFLKGLNGDALIVSRRHVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEHHHHHH
VRKMMQGL
HHHHHHCC
>Mature Secondary Structure
MNVLIVDDEPLARERLSRMVSELEGYTVLEPSATNGEEALALIDSHKPDIVLLDIRMPGL
CEEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCHHHEEEEECCCCCEEEEEEECCCC
DGLQVAARLCERETPPAVVFCAGPDEFAVEALQASAVGYVVKPVRTEHLHDALKRAERPN
CHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
RAQLSALTRPAAESGNGPRSHISARTRKGIELIPLDQVVYFIADHKYVTLRHEAGEVLLD
HHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHEECCEEEEEECCCCCHHHH
EPLKALEDEFGERFVRIHRNALVARDRIERLQRTPLGHFQLFLKGLNGDALIVSRRHVAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEHHHHHH
VRKMMQGL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2493441; 10984043; 2544550; 8159168 [H]