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The map label for this gene is erg3 [H]

Identifier: 77461688

GI number: 77461688

Start: 6134899

End: 6136134

Strand: Reverse

Name: erg3 [H]

Synonym: Pfl01_5467

Alternate gene names: 77461688

Gene position: 6136134-6134899 (Counterclockwise)

Preceding gene: 77461690

Following gene: 77461686

Centisome position: 95.31

GC content: 61.73

Gene sequence:

>1236_bases
ATGAACTTCATCCTGTATGCGGTACCGTTTTTCTTCGTATTGATTGCGGTGGAGCTCATCGCCGACCGTTGGCGCGGGGT
GAGCAACTATCGCCTGGCCGATGCGGTGAACAGCATCAGCACCGGGGTGTTGTCGACCACCACCGGCCTGTTGACCAAGG
GCGTGGGCCTGGTGACCTATGGGTTTGCCCAGGAGCATCTGGCGCTGTTCAGCTTGCCTGCGGACAGCGTCTGGGTCTGG
GTGTTTGCCTTTGTCCTCTATGACTTCTGCTATTACTGGCTGCACCGCATGGGCCATGAGCGCAACATCCTCTGGGCCGC
GCATTCGGTGCATCACCAGAGCGAGGACTACAATCTTTCCACGGCCTTGCGCCAGACCAGCACCGGGTTTCTGCTGAGCT
GGATCTTCTACCTGCCGATGGCCGTGTTCGGGGTGCCGTTGCTGGTGTTCGTCAGCGTTGCGGCGCTGAATCTGCTCTAT
CAGTTCTGGGTCCATACCCGGCACATTCCCAAGCTCGGCTGGTTCGAGTGGTGCTTCGTCACGCCGTCCAATCATCGGGC
CCACCATGCACAGAACGCTCTCTACATGGATCGCAACTACGGCGGGGTGTTCATTATTTGGGACCGTCTGTTCGGCTCGT
TCCAGGAAGAGGACGACAACGAGCCGGTGATTTTCGGCGTGACCACGCCGCTGGCGAGCTGGAATCCGTTGTGGGCCAAC
CTGCAGTTTTACGCGCAGCTGTGGGACGACGCGCGTCGGGCCGAGCGTACGTGGGACAAGCTCCGGATCTGGTTCATGCG
CACTGGCTGGCGTCCGGCGGACGTCGCGGCGAAGTACCCGATGAGCAAGCCTGACCTGAGTCAGTTCCGCAAATTCGAGG
TGCCGCTGGACAGCCGTCAACGGTGGTACGTGGGGTTGCAGTTTGGCGTCTATGTGGCGCTGGGCAGTTATCTGATGAAT
CTGGAACACAGTCTGCCCACCGGAGCATTGGTACTCGGCTGGGGCGCGGTGGCGTTCGGTTTGTTCGTGTTGGGCGTGGC
CCTGGAGAATCGCCCGTGGGCGGGTAAGCTGGAAGTGCTGCGGCTGGCATCGAACCTGCCGCTGGTGTGGCTGGCGCCGC
TGGTCGGGCTGTGGCCGGCCAGCCCGGGGATGTGGGTCGGCCTGCTCAGTTACAGCGTGCTCAGCGGCATCGGGCTGTAT
GGCTGTCGCCAGCGACTTACTCGGCTGGCGTCTTAG

Upstream 100 bases:

>100_bases
TTCATGGCGTTAAATGTCCTCTAATTTGTCGTTCGTTGCCATAGGATCAAGCCGCGGCTACACCTAGGATCTGTGCTACA
GATTCCGACCAGGGCGCGTC

Downstream 100 bases:

>100_bases
GATCGGCGGCGTTGGTCATTTCGGTTTTGTGTCGTTCGGCCTTGGCCAGCAGCTCGGCCTGTTCTTCCTCGTAAACCTTT
TTCGCCAGCCGGGCATTCTT

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNFILYAVPFFFVLIAVELIADRWRGVSNYRLADAVNSISTGVLSTTTGLLTKGVGLVTYGFAQEHLALFSLPADSVWVW
VFAFVLYDFCYYWLHRMGHERNILWAAHSVHHQSEDYNLSTALRQTSTGFLLSWIFYLPMAVFGVPLLVFVSVAALNLLY
QFWVHTRHIPKLGWFEWCFVTPSNHRAHHAQNALYMDRNYGGVFIIWDRLFGSFQEEDDNEPVIFGVTTPLASWNPLWAN
LQFYAQLWDDARRAERTWDKLRIWFMRTGWRPADVAAKYPMSKPDLSQFRKFEVPLDSRQRWYVGLQFGVYVALGSYLMN
LEHSLPTGALVLGWGAVAFGLFVLGVALENRPWAGKLEVLRLASNLPLVWLAPLVGLWPASPGMWVGLLSYSVLSGIGLY
GCRQRLTRLAS

Sequences:

>Translated_411_residues
MNFILYAVPFFFVLIAVELIADRWRGVSNYRLADAVNSISTGVLSTTTGLLTKGVGLVTYGFAQEHLALFSLPADSVWVW
VFAFVLYDFCYYWLHRMGHERNILWAAHSVHHQSEDYNLSTALRQTSTGFLLSWIFYLPMAVFGVPLLVFVSVAALNLLY
QFWVHTRHIPKLGWFEWCFVTPSNHRAHHAQNALYMDRNYGGVFIIWDRLFGSFQEEDDNEPVIFGVTTPLASWNPLWAN
LQFYAQLWDDARRAERTWDKLRIWFMRTGWRPADVAAKYPMSKPDLSQFRKFEVPLDSRQRWYVGLQFGVYVALGSYLMN
LEHSLPTGALVLGWGAVAFGLFVLGVALENRPWAGKLEVLRLASNLPLVWLAPLVGLWPASPGMWVGLLSYSVLSGIGLY
GCRQRLTRLAS
>Mature_411_residues
MNFILYAVPFFFVLIAVELIADRWRGVSNYRLADAVNSISTGVLSTTTGLLTKGVGLVTYGFAQEHLALFSLPADSVWVW
VFAFVLYDFCYYWLHRMGHERNILWAAHSVHHQSEDYNLSTALRQTSTGFLLSWIFYLPMAVFGVPLLVFVSVAALNLLY
QFWVHTRHIPKLGWFEWCFVTPSNHRAHHAQNALYMDRNYGGVFIIWDRLFGSFQEEDDNEPVIFGVTTPLASWNPLWAN
LQFYAQLWDDARRAERTWDKLRIWFMRTGWRPADVAAKYPMSKPDLSQFRKFEVPLDSRQRWYVGLQFGVYVALGSYLMN
LEHSLPTGALVLGWGAVAFGLFVLGVALENRPWAGKLEVLRLASNLPLVWLAPLVGLWPASPGMWVGLLSYSVLSGIGLY
GCRQRLTRLAS

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=384, Percent_Identity=37.7604166666667, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI25144659, Length=222, Percent_Identity=36.9369369369369, Blast_Score=155, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 47018; Mature: 47018

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFILYAVPFFFVLIAVELIADRWRGVSNYRLADAVNSISTGVLSTTTGLLTKGVGLVTY
CCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEE
GFAQEHLALFSLPADSVWVWVFAFVLYDFCYYWLHRMGHERNILWAAHSVHHQSEDYNLS
CHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCHH
TALRQTSTGFLLSWIFYLPMAVFGVPLLVFVSVAALNLLYQFWVHTRHIPKLGWFEWCFV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
TPSNHRAHHAQNALYMDRNYGGVFIIWDRLFGSFQEEDDNEPVIFGVTTPLASWNPLWAN
CCCCCCHHHHCCCEEEECCCCCEEEEHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHH
LQFYAQLWDDARRAERTWDKLRIWFMRTGWRPADVAAKYPMSKPDLSQFRKFEVPLDSRQ
HHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHCCCCCCCCHHHHHEECCCCCCCC
RWYVGLQFGVYVALGSYLMNLEHSLPTGALVLGWGAVAFGLFVLGVALENRPWAGKLEVL
EEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RLASNLPLVWLAPLVGLWPASPGMWVGLLSYSVLSGIGLYGCRQRLTRLAS
HHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNFILYAVPFFFVLIAVELIADRWRGVSNYRLADAVNSISTGVLSTTTGLLTKGVGLVTY
CCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEE
GFAQEHLALFSLPADSVWVWVFAFVLYDFCYYWLHRMGHERNILWAAHSVHHQSEDYNLS
CHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCHH
TALRQTSTGFLLSWIFYLPMAVFGVPLLVFVSVAALNLLYQFWVHTRHIPKLGWFEWCFV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
TPSNHRAHHAQNALYMDRNYGGVFIIWDRLFGSFQEEDDNEPVIFGVTTPLASWNPLWAN
CCCCCCHHHHCCCEEEECCCCCEEEEHHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHH
LQFYAQLWDDARRAERTWDKLRIWFMRTGWRPADVAAKYPMSKPDLSQFRKFEVPLDSRQ
HHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHCCCCCCCCHHHHHEECCCCCCCC
RWYVGLQFGVYVALGSYLMNLEHSLPTGALVLGWGAVAFGLFVLGVALENRPWAGKLEVL
EEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RLASNLPLVWLAPLVGLWPASPGMWVGLLSYSVLSGIGLYGCRQRLTRLAS
HHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]