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The map label for this gene is btuB [H]

Identifier: 77459962

GI number: 77459962

Start: 4225635

End: 4228340

Strand: Direct

Name: btuB [H]

Synonym: Pfl01_3740

Alternate gene names: 77459962

Gene position: 4225635-4228340 (Clockwise)

Preceding gene: 77459961

Following gene: 77459963

Centisome position: 65.63

GC content: 64.49

Gene sequence:

>2706_bases
ATGCTGATGAACACTCCACGCTTCACGCTCAAACCCTTGGTGGCGACGATTTCCCGCCACCGTTTCGTTCCGTTGTACCT
GGTGGCCATGGGGATGGGCGCCGGGGTTCAGGCCGCCGAGGACGACAACGGCGTCCCGGCCGCCGCTGCGGTGGTTGCGC
CGACCACGCAACTGCAACGGGTCGAAGTGACCGGTTCGGCGATTCGCCGGGTCGATGCGGAAACGGCGGTGCCGATCACC
GTGCTCAAGGCCGATGAACTGCGCAAACAGGGCGTGACCACCACCGCCGAACTGGTGCAGCGCATCACCGGCAGCCAGTC
GATCAACAACAGCGCAGGCTCGGTCGGCGCAGCCACCGGCGGCGCATCGTTTGCCGACATGCGCGGCATCGGCGCGAACA
AGACGCTGGTGCTGCTCAACGGTCGCCGACTGGCCAACAACGCCCTGTCGGGCACCAACTCGGCCGGCGGCGCGGTGGAT
CTGAACATGATCCCGTTTGCCGCGATCGAGCGCGTGGAAGTGCTGCGCGACGGCGCCTCGGCCCTGTACGGCACCGACGC
CATCGGCGGCGTGATCAACTTCATCACCAAGAAATCCATGACCGACGGCCAGCTCACCCTCGGCGGCGAAACCCCAACCC
ACAGCGGCGGCGGTGCGACCAAGGACATGAGCGCCAGTTGGGGCTACGGCGATCTGGAGCAGGACCGCTTCAACGTGCTC
GGTGTGTTCAACTACAACAAGCAACAGAACCTCGACGCCAACGACCGCTCCTTCGCCCGTGACTACGTGCCCGGCCGAGG
TCTCGACCAGACCTCCGGCACCGCGTTCCCCGGCAACTACAGCCAGAACGGCAACGCCACCAACCCGCTGGCCAACAGCA
ATTGCAACGGCCCCAACCTGGTGGCCCGCGACGGCCTCTGCCGCTTCAGCACCCGGGAATTCATCGACCTGGTGCCGCAG
ACCGAGAAGACGTCGTTCTTCGGCAAGACCACCGGCAAACTGGCCGACGACCACAACGTCAACCTTGAATACTTCTGGTC
GCGCAACAACAACGCCACCGCTGTCGGCCCGGCGCCATTGACCGGCCTGAGCCTGGATTCGTCCTCGCCCTACTACCCCG
GCAACGGCATCACCCCGGCGCCCACCGATTTTGCCCTCGACCCGACGCAACCGGTGGACGTGAACTGGCGCGAAACCGCC
GCCGGCCCGCGTGAATCGAAAGACCAGAACACCAGCCAGCGCTTTTTGCTGAGCTTCGACGGTCTGGTGGGCGGCTGGGA
CTACAACGTCGGCGCCTCGTACAACCAGAACAAGATCGTCTCCAGCGTTACCAGCGGCTACGTCAGCGATCAGGCGATGA
TCGACGGTCTGGCCAGCGGCCTGCTCAACCCGTTCGGCCCGCAGACCAGCGCCGGTCAGCAATACATCGACCAGGCCGCG
TACCACGGCGCCTATTCCACGGCGGTCGGTCGGGTCGCCGGTTTCGACGGGCGGATCAGTCGCGAAATCGGTGACTGGTT
CGGCGCCGGCCCGTCGGGTCTGGCACTGGGCGGCGAGTACCGCAAAGAGAAATTCCACCAGGACTTCGAAGCCTTCGCCG
GCGACATCCAGAGCCTGGGCATCGACCCGGCCGGCAGCGTCGAGGGCGACCGCAGCGTTAAAGCCGCCTACGCGGAAATC
AACGTGCCGGTGCTCGACAGCCTGGAATTGTCCGCCGCCGTGCGTCACGACAAATACAGCGACTTCGGCAGCACCACCAA
CCCGAAATATTCGTTCCGTTATCAGCCGCTCAAGGAGCTGGTGGTGCGCGGCGCGTACAGCGAAGGCTTCCGCGCGCCGT
CGCTGTATGAGTTGTATTCGCCGCGCAGCATCACCTTCACCCAGGGCTACTACAACGACCCGGTGCTGTGTACTGGCGGC
GTGGTGCAACCGGGCGGCAACGGCGGGCGCGATTGCGGTCAGCAGTTCCTCAACCAGATCGGCGGCAACGAAGACCTGGC
CCCGGAGAAGGCGCGCAACGTGACGCTGGGCTTTGTCTATCAGCCGGTCAGCAATCTGTCCGTGGGCCTGGATTTCTGGT
GGATTCACATCTCCAACCAGATCCAGCCGTTCCCGGAATCCACCGTGTTCGATCAGGCCGGCAGCTACCCTGACCGCTTC
GTGCGCAACGCCGACGGCACGCTCAATTACATCGTCACCGGCAACGCCAACCTCGGCATCGTCGAAACCAACGGCGTCGA
TGTGTCGCTGGACTATCGCTTCCCGAACACGCCGTACGGTCAATTCGGCCTGGGCCTGCAAGGCACTTATGTCGACGAGT
ACGACTTCCAGAGCACCATCAAGGGCCCGTTCACCGACAAGGTCGGCGACTTCCGGGGTGACGGTGTGATCGCCCGCTGG
AAACACAACCTGACCGGTTCCTGGACCTTCGGCGCCGCCCGCGCGGCACTGACCAACCGCTTCACCACCGGCTACAACGA
CTACGACCGCGAGACCAACGCGCGGGTCGCGTCGTACTCGGTGTGGGACCTGTCGGCCGGTTACACCTTCGACAAGGTGC
TGGACGTCGATGCCGGGGTGAAGAACCTGTTCGACCGCGATCCGCCGTTCTCCAACCAGGCCTACAACTTCCAGAGCGGT
TATGACCCGCGCTACACCGATCCGCTGGGCCGTACGCTGTTTGCGCGCATGACGTACCACTTCTGA

Upstream 100 bases:

>100_bases
CTTGAAGAAAGTGGTTTTCGCGGCGCGGCACCACCGTGCTCCGTGCAAAGAGGGCTCACAAGGCCATTTCGATAAACGTC
TAACAAAGTCGGAAACAACC

Downstream 100 bases:

>100_bases
GTCCCGGTCGGGGCCGCGCAAGACTCCGGCCGGCCCCTTCCCCTTGCGAATTCGCATCCCGCAGCGGCCAGCCGCCGCTC
CGGGCTTTTCCCGCTCAGAG

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 901; Mature: 901

Protein sequence:

>901_residues
MLMNTPRFTLKPLVATISRHRFVPLYLVAMGMGAGVQAAEDDNGVPAAAAVVAPTTQLQRVEVTGSAIRRVDAETAVPIT
VLKADELRKQGVTTTAELVQRITGSQSINNSAGSVGAATGGASFADMRGIGANKTLVLLNGRRLANNALSGTNSAGGAVD
LNMIPFAAIERVEVLRDGASALYGTDAIGGVINFITKKSMTDGQLTLGGETPTHSGGGATKDMSASWGYGDLEQDRFNVL
GVFNYNKQQNLDANDRSFARDYVPGRGLDQTSGTAFPGNYSQNGNATNPLANSNCNGPNLVARDGLCRFSTREFIDLVPQ
TEKTSFFGKTTGKLADDHNVNLEYFWSRNNNATAVGPAPLTGLSLDSSSPYYPGNGITPAPTDFALDPTQPVDVNWRETA
AGPRESKDQNTSQRFLLSFDGLVGGWDYNVGASYNQNKIVSSVTSGYVSDQAMIDGLASGLLNPFGPQTSAGQQYIDQAA
YHGAYSTAVGRVAGFDGRISREIGDWFGAGPSGLALGGEYRKEKFHQDFEAFAGDIQSLGIDPAGSVEGDRSVKAAYAEI
NVPVLDSLELSAAVRHDKYSDFGSTTNPKYSFRYQPLKELVVRGAYSEGFRAPSLYELYSPRSITFTQGYYNDPVLCTGG
VVQPGGNGGRDCGQQFLNQIGGNEDLAPEKARNVTLGFVYQPVSNLSVGLDFWWIHISNQIQPFPESTVFDQAGSYPDRF
VRNADGTLNYIVTGNANLGIVETNGVDVSLDYRFPNTPYGQFGLGLQGTYVDEYDFQSTIKGPFTDKVGDFRGDGVIARW
KHNLTGSWTFGAARAALTNRFTTGYNDYDRETNARVASYSVWDLSAGYTFDKVLDVDAGVKNLFDRDPPFSNQAYNFQSG
YDPRYTDPLGRTLFARMTYHF

Sequences:

>Translated_901_residues
MLMNTPRFTLKPLVATISRHRFVPLYLVAMGMGAGVQAAEDDNGVPAAAAVVAPTTQLQRVEVTGSAIRRVDAETAVPIT
VLKADELRKQGVTTTAELVQRITGSQSINNSAGSVGAATGGASFADMRGIGANKTLVLLNGRRLANNALSGTNSAGGAVD
LNMIPFAAIERVEVLRDGASALYGTDAIGGVINFITKKSMTDGQLTLGGETPTHSGGGATKDMSASWGYGDLEQDRFNVL
GVFNYNKQQNLDANDRSFARDYVPGRGLDQTSGTAFPGNYSQNGNATNPLANSNCNGPNLVARDGLCRFSTREFIDLVPQ
TEKTSFFGKTTGKLADDHNVNLEYFWSRNNNATAVGPAPLTGLSLDSSSPYYPGNGITPAPTDFALDPTQPVDVNWRETA
AGPRESKDQNTSQRFLLSFDGLVGGWDYNVGASYNQNKIVSSVTSGYVSDQAMIDGLASGLLNPFGPQTSAGQQYIDQAA
YHGAYSTAVGRVAGFDGRISREIGDWFGAGPSGLALGGEYRKEKFHQDFEAFAGDIQSLGIDPAGSVEGDRSVKAAYAEI
NVPVLDSLELSAAVRHDKYSDFGSTTNPKYSFRYQPLKELVVRGAYSEGFRAPSLYELYSPRSITFTQGYYNDPVLCTGG
VVQPGGNGGRDCGQQFLNQIGGNEDLAPEKARNVTLGFVYQPVSNLSVGLDFWWIHISNQIQPFPESTVFDQAGSYPDRF
VRNADGTLNYIVTGNANLGIVETNGVDVSLDYRFPNTPYGQFGLGLQGTYVDEYDFQSTIKGPFTDKVGDFRGDGVIARW
KHNLTGSWTFGAARAALTNRFTTGYNDYDRETNARVASYSVWDLSAGYTFDKVLDVDAGVKNLFDRDPPFSNQAYNFQSG
YDPRYTDPLGRTLFARMTYHF
>Mature_901_residues
MLMNTPRFTLKPLVATISRHRFVPLYLVAMGMGAGVQAAEDDNGVPAAAAVVAPTTQLQRVEVTGSAIRRVDAETAVPIT
VLKADELRKQGVTTTAELVQRITGSQSINNSAGSVGAATGGASFADMRGIGANKTLVLLNGRRLANNALSGTNSAGGAVD
LNMIPFAAIERVEVLRDGASALYGTDAIGGVINFITKKSMTDGQLTLGGETPTHSGGGATKDMSASWGYGDLEQDRFNVL
GVFNYNKQQNLDANDRSFARDYVPGRGLDQTSGTAFPGNYSQNGNATNPLANSNCNGPNLVARDGLCRFSTREFIDLVPQ
TEKTSFFGKTTGKLADDHNVNLEYFWSRNNNATAVGPAPLTGLSLDSSSPYYPGNGITPAPTDFALDPTQPVDVNWRETA
AGPRESKDQNTSQRFLLSFDGLVGGWDYNVGASYNQNKIVSSVTSGYVSDQAMIDGLASGLLNPFGPQTSAGQQYIDQAA
YHGAYSTAVGRVAGFDGRISREIGDWFGAGPSGLALGGEYRKEKFHQDFEAFAGDIQSLGIDPAGSVEGDRSVKAAYAEI
NVPVLDSLELSAAVRHDKYSDFGSTTNPKYSFRYQPLKELVVRGAYSEGFRAPSLYELYSPRSITFTQGYYNDPVLCTGG
VVQPGGNGGRDCGQQFLNQIGGNEDLAPEKARNVTLGFVYQPVSNLSVGLDFWWIHISNQIQPFPESTVFDQAGSYPDRF
VRNADGTLNYIVTGNANLGIVETNGVDVSLDYRFPNTPYGQFGLGLQGTYVDEYDFQSTIKGPFTDKVGDFRGDGVIARW
KHNLTGSWTFGAARAALTNRFTTGYNDYDRETNARVASYSVWDLSAGYTFDKVLDVDAGVKNLFDRDPPFSNQAYNFQSG
YDPRYTDPLGRTLFARMTYHF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=179, Percent_Identity=29.608938547486, Blast_Score=83, Evalue=9e-17,
Organism=Escherichia coli, GI1790405, Length=161, Percent_Identity=29.8136645962733, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1786798, Length=151, Percent_Identity=32.4503311258278, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 97100; Mature: 97100

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMNTPRFTLKPLVATISRHRFVPLYLVAMGMGAGVQAAEDDNGVPAAAAVVAPTTQLQR
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEE
VEVTGSAIRRVDAETAVPITVLKADELRKQGVTTTAELVQRITGSQSINNSAGSVGAATG
EEECHHHHHHCCCCCCCCEEEEEHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
GASFADMRGIGANKTLVLLNGRRLANNALSGTNSAGGAVDLNMIPFAAIERVEVLRDGAS
CCCHHHHCCCCCCCEEEEECCCCHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCH
ALYGTDAIGGVINFITKKSMTDGQLTLGGETPTHSGGGATKDMSASWGYGDLEQDRFNVL
HHHCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
GVFNYNKQQNLDANDRSFARDYVPGRGLDQTSGTAFPGNYSQNGNATNPLANSNCNGPNL
EEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
VARDGLCRFSTREFIDLVPQTEKTSFFGKTTGKLADDHNVNLEYFWSRNNNATAVGPAPL
EECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCC
TGLSLDSSSPYYPGNGITPAPTDFALDPTQPVDVNWRETAAGPRESKDQNTSQRFLLSFD
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEC
GLVGGWDYNVGASYNQNKIVSSVTSGYVSDQAMIDGLASGLLNPFGPQTSAGQQYIDQAA
CEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
YHGAYSTAVGRVAGFDGRISREIGDWFGAGPSGLALGGEYRKEKFHQDFEAFAGDIQSLG
HCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
IDPAGSVEGDRSVKAAYAEINVPVLDSLELSAAVRHDKYSDFGSTTNPKYSFRYQPLKEL
CCCCCCCCCCCCEEEEEEEECCCEECCCHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHH
VVRGAYSEGFRAPSLYELYSPRSITFTQGYYNDPVLCTGGVVQPGGNGGRDCGQQFLNQI
HHHCCHHCCCCCCCHHHHCCCCEEEEECCCCCCCEEEECCEECCCCCCCHHHHHHHHHHH
GGNEDLAPEKARNVTLGFVYQPVSNLSVGLDFWWIHISNQIQPFPESTVFDQAGSYPDRF
CCCCCCCCHHHCCEEEEEEECCCCCCEECEEEEEEEECCCCCCCCCCHHHHCCCCCHHHH
VRNADGTLNYIVTGNANLGIVETNGVDVSLDYRFPNTPYGQFGLGLQGTYVDEYDFQSTI
HHCCCCEEEEEEECCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHC
KGPFTDKVGDFRGDGVIARWKHNLTGSWTFGAARAALTNRFTTGYNDYDRETNARVASYS
CCCCCCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEE
VWDLSAGYTFDKVLDVDAGVKNLFDRDPPFSNQAYNFQSGYDPRYTDPLGRTLFARMTYH
EEECCCCCCHHHHEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
F
C
>Mature Secondary Structure
MLMNTPRFTLKPLVATISRHRFVPLYLVAMGMGAGVQAAEDDNGVPAAAAVVAPTTQLQR
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEE
VEVTGSAIRRVDAETAVPITVLKADELRKQGVTTTAELVQRITGSQSINNSAGSVGAATG
EEECHHHHHHCCCCCCCCEEEEEHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
GASFADMRGIGANKTLVLLNGRRLANNALSGTNSAGGAVDLNMIPFAAIERVEVLRDGAS
CCCHHHHCCCCCCCEEEEECCCCHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCH
ALYGTDAIGGVINFITKKSMTDGQLTLGGETPTHSGGGATKDMSASWGYGDLEQDRFNVL
HHHCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
GVFNYNKQQNLDANDRSFARDYVPGRGLDQTSGTAFPGNYSQNGNATNPLANSNCNGPNL
EEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
VARDGLCRFSTREFIDLVPQTEKTSFFGKTTGKLADDHNVNLEYFWSRNNNATAVGPAPL
EECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCC
TGLSLDSSSPYYPGNGITPAPTDFALDPTQPVDVNWRETAAGPRESKDQNTSQRFLLSFD
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEEEEC
GLVGGWDYNVGASYNQNKIVSSVTSGYVSDQAMIDGLASGLLNPFGPQTSAGQQYIDQAA
CEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
YHGAYSTAVGRVAGFDGRISREIGDWFGAGPSGLALGGEYRKEKFHQDFEAFAGDIQSLG
HCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
IDPAGSVEGDRSVKAAYAEINVPVLDSLELSAAVRHDKYSDFGSTTNPKYSFRYQPLKEL
CCCCCCCCCCCCEEEEEEEECCCEECCCHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHH
VVRGAYSEGFRAPSLYELYSPRSITFTQGYYNDPVLCTGGVVQPGGNGGRDCGQQFLNQI
HHHCCHHCCCCCCCHHHHCCCCEEEEECCCCCCCEEEECCEECCCCCCCHHHHHHHHHHH
GGNEDLAPEKARNVTLGFVYQPVSNLSVGLDFWWIHISNQIQPFPESTVFDQAGSYPDRF
CCCCCCCCHHHCCEEEEEEECCCCCCEECEEEEEEEECCCCCCCCCCHHHHCCCCCHHHH
VRNADGTLNYIVTGNANLGIVETNGVDVSLDYRFPNTPYGQFGLGLQGTYVDEYDFQSTI
HHCCCCEEEEEEECCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHC
KGPFTDKVGDFRGDGVIARWKHNLTGSWTFGAARAALTNRFTTGYNDYDRETNARVASYS
CCCCCCCCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEE
VWDLSAGYTFDKVLDVDAGVKNLFDRDPPFSNQAYNFQSGYDPRYTDPLGRTLFARMTYH
EEECCCCCCHHHHEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11598060 [H]