Click here to switch to the map view.

The map label for this gene is ttuB [H]

Identifier: 77459942

GI number: 77459942

Start: 4205286

End: 4206632

Strand: Direct

Name: ttuB [H]

Synonym: Pfl01_3720

Alternate gene names: 77459942

Gene position: 4205286-4206632 (Clockwise)

Preceding gene: 77459940

Following gene: 77459943

Centisome position: 65.32

GC content: 60.13

Gene sequence:

>1347_bases
GTGAAATCATCCATCGCCGGGATGAACGAGGGCGCCGATTCGGTGCTGTCCTCCGCCATTGCCAAAGTCAAACGCCACGT
CCTGCCGCTGTTCGTCATCATGTTCATCGTCAATTACATTGACCGGGTGAACATCGGTTTCGTCCGTACCCACATGGAAC
ACGACCTCGGCATCGGTGCCGCGGCCTACGGTTTCGGTGCCGGTCTGTTCTTCATCGGTTACGCGCTGTTCGAAGTCCCT
TCCAACATGTTGCTGCAAAAGGTCGGCGCGCGAATCTGGCTGACCCGCATCATGCTCACCTGGGGCCTGGTCGCCGCCGG
CATGGCGTTCATCCAGAACGAAACCCACTTCTACATCCTGCGTTTTCTGCTCGGCGTGGCCGAGGCCGGGTTCTTTCCCG
GGGTGATCTACTACTTCACCCGCTGGTTGCCGGGGGCCGAACGCGGCAAGGCGATTGCGATTTTCTTGAGCGGTTCGGCC
GTGGCCTCGCTGATTTCCGGCCCGTTGTCTGGTCTGTTGCTGCAGATCGAAGGTCTCGGCATGCACGGCTGGCAGTGGAT
GTATTTCATTGAAGGGATGTTCTCGGTCGGCCTGTGCGTATTCGTCTGGTTCTGGCTCGACGCCAAACCTCACGATGCGA
AATGGCTGACCCGCGCCGAGCAGGATGCACTGGTCAAAGCCATCGACGATGAGCAGAAGGCCCGCGAAGCTGCGACCCCG
ATCCGGCCGTCGCTGGGCAAACTGCTCAAGGATCGCCAGATCATCCTGTTCTGCCTGATCTACTTCTTCATTCAATTGAC
GATCTACGCCGCGACGTTCTGGCTGCCGAGCATCATCAAGAAGATGGGCGAAATGAGTGACTTCCAGGTCGGCCTGTTCA
ACTCGATTCCGTGGTTGCTGTCGATCATCGGCATGTACGCGTTCGCCTCGTTCTCGGCGAAGTGGAAACACCAGCAGGCG
TGGGTCGCCACTGCATTGCTGATCGCCGCTGCGGGGATGTTCATGTCCACCACCGGCGGGCCGATCTTCGCTTTTGTCGC
AATCTGCTTTGCTGCGCTGGGTTTCAAATCCGCGTCCTCGCTGTTCTGGCCGATCCCGCAGGCCTATCTCGATGCGCGGA
TCGCCGCTGCCGTCATCGCGTTGATCAACTCGGTGGGCAACCTCGGCGGTTTCGTCGCTCCGACCACATTCGGCTTGCTG
GAACAACACACCGGTTCGATCCAGGGCGGCCTCTATGGCCTGGCCGCGACCTCGATCATTGCCGCGATCATCGTGTTCGC
CGCCCGCATGACACCCAAATCCGCCCCTGACGTCGCCGTGGCCGATGCCGCGCCGAAACACGCTTGA

Upstream 100 bases:

>100_bases
ACTCCCGCTTGTAGGACAAAAAAATCTAGTTGTATGATGTCTATCAACAACGCAACACCAGACACACCCCGCATAAAAAT
AACGAGTGGGAGAAAACCAA

Downstream 100 bases:

>100_bases
AAGGACAATCCCAAATGACCGCACACGACATCGCCAAAGCCCCGATCATCACCGAGATGCAAGTCATCCCGGTCGCCGGC
CACGACGGCATGCTGCTCAA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKSSIAGMNEGADSVLSSAIAKVKRHVLPLFVIMFIVNYIDRVNIGFVRTHMEHDLGIGAAAYGFGAGLFFIGYALFEVP
SNMLLQKVGARIWLTRIMLTWGLVAAGMAFIQNETHFYILRFLLGVAEAGFFPGVIYYFTRWLPGAERGKAIAIFLSGSA
VASLISGPLSGLLLQIEGLGMHGWQWMYFIEGMFSVGLCVFVWFWLDAKPHDAKWLTRAEQDALVKAIDDEQKAREAATP
IRPSLGKLLKDRQIILFCLIYFFIQLTIYAATFWLPSIIKKMGEMSDFQVGLFNSIPWLLSIIGMYAFASFSAKWKHQQA
WVATALLIAAAGMFMSTTGGPIFAFVAICFAALGFKSASSLFWPIPQAYLDARIAAAVIALINSVGNLGGFVAPTTFGLL
EQHTGSIQGGLYGLAATSIIAAIIVFAARMTPKSAPDVAVADAAPKHA

Sequences:

>Translated_448_residues
MKSSIAGMNEGADSVLSSAIAKVKRHVLPLFVIMFIVNYIDRVNIGFVRTHMEHDLGIGAAAYGFGAGLFFIGYALFEVP
SNMLLQKVGARIWLTRIMLTWGLVAAGMAFIQNETHFYILRFLLGVAEAGFFPGVIYYFTRWLPGAERGKAIAIFLSGSA
VASLISGPLSGLLLQIEGLGMHGWQWMYFIEGMFSVGLCVFVWFWLDAKPHDAKWLTRAEQDALVKAIDDEQKAREAATP
IRPSLGKLLKDRQIILFCLIYFFIQLTIYAATFWLPSIIKKMGEMSDFQVGLFNSIPWLLSIIGMYAFASFSAKWKHQQA
WVATALLIAAAGMFMSTTGGPIFAFVAICFAALGFKSASSLFWPIPQAYLDARIAAAVIALINSVGNLGGFVAPTTFGLL
EQHTGSIQGGLYGLAATSIIAAIIVFAARMTPKSAPDVAVADAAPKHA
>Mature_448_residues
MKSSIAGMNEGADSVLSSAIAKVKRHVLPLFVIMFIVNYIDRVNIGFVRTHMEHDLGIGAAAYGFGAGLFFIGYALFEVP
SNMLLQKVGARIWLTRIMLTWGLVAAGMAFIQNETHFYILRFLLGVAEAGFFPGVIYYFTRWLPGAERGKAIAIFLSGSA
VASLISGPLSGLLLQIEGLGMHGWQWMYFIEGMFSVGLCVFVWFWLDAKPHDAKWLTRAEQDALVKAIDDEQKAREAATP
IRPSLGKLLKDRQIILFCLIYFFIQLTIYAATFWLPSIIKKMGEMSDFQVGLFNSIPWLLSIIGMYAFASFSAKWKHQQA
WVATALLIAAAGMFMSTTGGPIFAFVAICFAALGFKSASSLFWPIPQAYLDARIAAAVIALINSVGNLGGFVAPTTFGLL
EQHTGSIQGGLYGLAATSIIAAIIVFAARMTPKSAPDVAVADAAPKHA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=388, Percent_Identity=23.4536082474227, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI21322234, Length=367, Percent_Identity=24.5231607629428, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082071, Length=431, Percent_Identity=34.338747099768, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI87082320, Length=427, Percent_Identity=23.8875878220141, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789152, Length=440, Percent_Identity=24.3181818181818, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789515, Length=433, Percent_Identity=23.3256351039261, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI2367379, Length=404, Percent_Identity=22.029702970297, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI2367193, Length=285, Percent_Identity=21.4035087719298, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321698, Length=319, Percent_Identity=22.257053291536, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319876, Length=456, Percent_Identity=21.2719298245614, Blast_Score=87, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322025, Length=228, Percent_Identity=25, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=217, Percent_Identity=21.6589861751152, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319250, Length=220, Percent_Identity=25, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24639764, Length=368, Percent_Identity=22.8260869565217, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI20130167, Length=425, Percent_Identity=21.8823529411765, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641682, Length=387, Percent_Identity=24.031007751938, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24583789, Length=361, Percent_Identity=22.7146814404432, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48753; Mature: 48753

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCCEECCCCCCCC
>Mature Secondary Structure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HHHHHHHHHCCCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]