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The map label for this gene is clpX [H]

Identifier: 77459918

GI number: 77459918

Start: 4184372

End: 4185655

Strand: Reverse

Name: clpX [H]

Synonym: Pfl01_3696

Alternate gene names: 77459918

Gene position: 4185655-4184372 (Counterclockwise)

Preceding gene: 77459919

Following gene: 77459917

Centisome position: 65.01

GC content: 55.69

Gene sequence:

>1284_bases
ATGACTGACACCCGCAACGGCGAGGACAACGGCAAGCTGCTCTATTGCTCCTTCTGTGGCAAAAGCCAGCATGAAGTGCG
CAAATTGATTGCCGGCCCCTCGGTCTTTATCTGCGACGAGTGCGTCGACCTGTGCAATGACATCATCCGCGAGGAGGTGC
AGGAAGCACAGGCCGAAAGCAGCGCGCATAAATTGCCTTCGCCTAAAGAAATCAGCGGCATCCTTGATCAGTATGTAATT
GGTCAGGAACGTGCCAAGAAGGTTCTGGCAGTAGCGGTGTACAACCACTACAAGCGTCTGAACCAGCGTGACAAAAAGGC
TGACGACGTCGAACTCGGCAAGAGCAACATCCTGCTGATCGGCCCGACAGGCTCTGGTAAAACCCTGCTGGCCGAAACCC
TGGCCCGTTTGCTGAACGTTCCGTTCACCATCGCCGACGCAACCACCCTCACCGAGGCGGGTTATGTGGGTGAAGACGTC
GAGAACATCATTCAGAAGCTGCTGCAGAAGTGCGATTACGATGTAGAGAAAGCCCAGATGGGGATTGTCTATATCGACGA
AATCGACAAGATTTCCCGCAAGTCCGACAACCCGTCGATCACCCGAGACGTTTCCGGTGAAGGCGTGCAGCAGGCCTTGC
TCAAGCTGATCGAAGGCACGGTCGCTTCCGTTCCGCCGCAAGGTGGCCGCAAGCATCCGCAGCAGGAATTCCTTCAGGTT
GATACCCGTAACATTCTGTTCATCTGCGGTGGCGCATTCTCCGGTTTGGAGAAGGTCATTCAGAACCGTTCCACCAAGGG
TGGCATCGGTTTCAACGCAGAAGTGCGCAGCAAGGAAGAGGGCAAGAAAGTCGGTGAATCCCTGCGTGAAGTCGAGCCTG
ACGATCTGGTCAAGTTCGGTCTGATCCCGGAGTTCGTCGGTCGTCTGCCGGTTCTTGCGACGCTGGACGAGCTGGATGAG
GCTGCTTTGATGCAGATTCTCACCGAGCCGAAAAATGCCCTGACCAAACAGTATGCCAAGCTGTTCGAGATGGAAGGCGT
AGATCTGGAGTTCCGTTCCGACGCGCTGAAGTCGGTCGCCAAGCGTGCCCTGGAGCGTAAAACCGGTGCCCGTGGCCTGC
GTTCGATTCTCGAAGGTGTACTGCTCGACACGATGTATGAAATCCCCTCGCAGTCCGAGGTGAGCAAAGTCGTGATCGAT
GAAAGTGTGATCGAAGGCAAGTCCAAGCCACTGTATATCTATGAAAACAGTGAGCCGGCTGCCAAGGCTGCGCCGGACGC
GTAA

Upstream 100 bases:

>100_bases
AAAATAGGCTTGGTCGGCGCGTCTGATCAGCGGCGGGCTTGAAAAAGCCCGCAATAGCCTTCATCTTGTGTTGCAAGCCT
ATCGGATTTGGATCGAACGA

Downstream 100 bases:

>100_bases
GCGCCCGGGCTGCCGGAACAAGGAAGGGGCCTTCGGGCCTCTTTTTTTTTATGTCGTTTTTTACATCCGCTTTGCGCTTG
TTTTTTTTCAAGTCAGCCCC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSAHKLPSPKEISGILDQYVI
GQERAKKVLAVAVYNHYKRLNQRDKKADDVELGKSNILLIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTRNILFICGGAFSGLEKVIQNRSTKGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFGLIPEFVGRLPVLATLDELDE
AALMQILTEPKNALTKQYAKLFEMEGVDLEFRSDALKSVAKRALERKTGARGLRSILEGVLLDTMYEIPSQSEVSKVVID
ESVIEGKSKPLYIYENSEPAAKAAPDA

Sequences:

>Translated_427_residues
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSAHKLPSPKEISGILDQYVI
GQERAKKVLAVAVYNHYKRLNQRDKKADDVELGKSNILLIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTRNILFICGGAFSGLEKVIQNRSTKGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFGLIPEFVGRLPVLATLDELDE
AALMQILTEPKNALTKQYAKLFEMEGVDLEFRSDALKSVAKRALERKTGARGLRSILEGVLLDTMYEIPSQSEVSKVVID
ESVIEGKSKPLYIYENSEPAAKAAPDA
>Mature_426_residues
TDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAESSAHKLPSPKEISGILDQYVIG
QERAKKVLAVAVYNHYKRLNQRDKKADDVELGKSNILLIGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQMGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVD
TRNILFICGGAFSGLEKVIQNRSTKGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFGLIPEFVGRLPVLATLDELDEA
ALMQILTEPKNALTKQYAKLFEMEGVDLEFRSDALKSVAKRALERKTGARGLRSILEGVLLDTMYEIPSQSEVSKVVIDE
SVIEGKSKPLYIYENSEPAAKAAPDA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=333, Percent_Identity=52.8528528528528, Blast_Score=327, Evalue=1e-89,
Organism=Escherichia coli, GI1786642, Length=425, Percent_Identity=76.2352941176471, Blast_Score=648, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=101, Percent_Identity=44.5544554455446, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=326, Percent_Identity=46.319018404908, Blast_Score=275, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=326, Percent_Identity=46.319018404908, Blast_Score=274, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=390, Percent_Identity=40.5128205128205, Blast_Score=262, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=42.8, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=432, Percent_Identity=40.5092592592593, Blast_Score=281, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24648291, Length=326, Percent_Identity=48.159509202454, Blast_Score=302, Evalue=4e-82,
Organism=Drosophila melanogaster, GI24648289, Length=326, Percent_Identity=48.159509202454, Blast_Score=301, Evalue=4e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46913; Mature: 46782

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAES
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
SAHKLPSPKEISGILDQYVIGQERAKKVLAVAVYNHYKRLNQRDKKADDVELGKSNILLI
HHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEE
GPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQM
ECCCCCCHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
CEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHH
DTRNILFICGGAFSGLEKVIQNRSTKGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFG
CCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHC
LIPEFVGRLPVLATLDELDEAALMQILTEPKNALTKQYAKLFEMEGVDLEFRSDALKSVA
CCHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KRALERKTGARGLRSILEGVLLDTMYEIPSQSEVSKVVIDESVIEGKSKPLYIYENSEPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
AKAAPDA
CCCCCCC
>Mature Secondary Structure 
TDTRNGEDNGKLLYCSFCGKSQHEVRKLIAGPSVFICDECVDLCNDIIREEVQEAQAES
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
SAHKLPSPKEISGILDQYVIGQERAKKVLAVAVYNHYKRLNQRDKKADDVELGKSNILLI
HHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEE
GPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQM
ECCCCCCHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
CEEEECCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHH
DTRNILFICGGAFSGLEKVIQNRSTKGGIGFNAEVRSKEEGKKVGESLREVEPDDLVKFG
CCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHC
LIPEFVGRLPVLATLDELDEAALMQILTEPKNALTKQYAKLFEMEGVDLEFRSDALKSVA
CCHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KRALERKTGARGLRSILEGVLLDTMYEIPSQSEVSKVVIDESVIEGKSKPLYIYENSEPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
AKAAPDA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]