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The map label for this gene is ppiD [H]

Identifier: 77459915

GI number: 77459915

Start: 4179288

End: 4181159

Strand: Reverse

Name: ppiD [H]

Synonym: Pfl01_3693

Alternate gene names: 77459915

Gene position: 4181159-4179288 (Counterclockwise)

Preceding gene: 77459916

Following gene: 77459913

Centisome position: 64.94

GC content: 59.35

Gene sequence:

>1872_bases
ATGCTGCAGAATATCAGGGACAATTCACAAGGCTGGATTGCCAAGACCATTATCGGAGTCATCGTTGCACTGATGGCTCT
GACCGGTTTCGACGCCATTTTCCAGGCCACGACTCACAAGAATGAGGCGGCCAAGGTCAACGGTGAAGAAATCAGCCAGA
ACGAGCTGAGCCAGGCGGTGGATATGCAACGCCGTCAGCTGATGCAACAACTGGGCAAGGACTTCGACGCTTCCTTGCTG
GACGAAAAAATGCTGCGCGAATCGGCCCTCAAGGGTCTGATCGATCGCAAGCTGCTGCTGCAAGGCGCAGAACAATCGAA
ATTCGCTTTCTCCGAAGCGGCCCTGGACCAAGTGATCCTGCAGACGCCTGAATTCCAGGTCGACGGCAAGTTCAGCTCCG
ACCGTTTCGATCAGGTGATCCGTCAACTGGGCTACAGCCGCATGCAGTTCCGCCAGATGCTGGCTCAGGAAATGCTGATC
GGCCAACTGCGCGCCGGTGTGGCGGGCAGCGGTTTCGTGACCGACGCTCAGGTGCTGGCCTTCGCCCGTCTGGAAAAACA
GACCCGCGACTTCGCCACGCTGAACATCAAGGCTGACCCTTCGGCCGTGAAGCTGACCGATGACGAGGTCAAGGCTTACT
ACGACGAGCACGCCAAGGAGTTCATGACCCCGGATCAAGTGGTCATCGATTACCTGGAATTGAAGAAGTCTTCGTTCTTC
GATCAGGTCGCCGTCAAGGACGAAGACCTGCAGGCGGCGTATCAGAAAGAGATCGCCAACCTGTCGGAACAGCGTCGTGC
GGCGCACATTCTGATCGAAGTCAACGACAAGACCACCGAGGCCCAGGCCAAGGCGAAGATCGAAGAAGTCCAGGCGCGTC
TGGCCAAGGGCGAGAAATTCGAAGCGCTGGCCAAGGAGTTCTCGCAGGATCCGGGTTCGGCCAACAACGGCGGTGACCTC
GGTTATGCCGGTCCTGGCGTTTACGATCCAGCCTTCGAAAAAGCCCTGTACTCTCTGAACAAGGATCAGGTTTCCGAGCC
GGTTCGCACCGACTTCGGTTTCCATCTGATCAAGCTGCTGGGTGTCGAGGCGCCTGAAGTGCCGACGCTGGCCAGCCTGA
AAGACAAGCTGACCCGCGAGCTGAAAACCCAGCAAGTCGAGCAGCGTTTCGTCGAGGCGACCAAGCAACTGGAAGACTCT
TCGTTCGAAGCCTCCGACCTGGCCCAGCCGGCGCAGGATCTTAAACTGACCGTGCACACCTCCAAGCCGTTCGGCCGTGA
AGGTGGCGAAGGCGTTGCAGCCAACCGTGCTGTAGTGACTGCCGCGTTCAGCACCGAAGTGCTGGAAGAGGGTGCCAACA
GCACCGCCATCGAGCTGGATCCGGAAACCGTGATCGTGCTGCGCGCCAAGGAGCACCTCAAGCCTGCTCAATTGCCGCTG
GAAAGCGTGGCTGCTGCCATTCGCACCCAGTTGACCAAAGAGCACGCCAGCGCGGCGGCCAAGACCCACGCCGAACAACT
GATCGCCAGTCTGCGTGATGGCAAGACGCCGTTGGACAAAGCGGTCGACGGTCAGAGCTGGAAAGTCACTGAAGCGGCGA
ACCGCGCTCAGGAAGGCGTTGACCCGGCGGTGCTGCAAGCACTGTTCCGCATGCCTAAGCCGGCTGCCAAGGACAAACCG
ACCTTCACCAGCGTGACGCTGGCGGATGGTAGCCTGACCATCGTGCGTCTGAACGGCGTGAACGAAGCGGCCGCTCCGAC
CGATGAAGAGAAAGCGCAGTACCGTCGCTTCCTCGCATCACGTGTGGGCCAGCAAGACTTCGCGGCGTACCGCAAGCAGC
TGGAAGCCGAAGCCGACATCAAGCGTTTCTGA

Upstream 100 bases:

>100_bases
TACGAGAAGGCGCATCCTCGGATGCGCCTTTCTTCTATCCGGATTCTACCCACGCTCCACGGTTGCCAAATTTTGAAGTT
CAACCGTTTCTGGGGGACGC

Downstream 100 bases:

>100_bases
TGCCTGGCTGAGCTGCAAGACCCGAGCCCCGGATGAAAATCCGGGGCTTTTTTATGCGCGTTATCCCGCGTTCGGGAAGC
CATGACTTCGGGCATTGACG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MLQNIRDNSQGWIAKTIIGVIVALMALTGFDAIFQATTHKNEAAKVNGEEISQNELSQAVDMQRRQLMQQLGKDFDASLL
DEKMLRESALKGLIDRKLLLQGAEQSKFAFSEAALDQVILQTPEFQVDGKFSSDRFDQVIRQLGYSRMQFRQMLAQEMLI
GQLRAGVAGSGFVTDAQVLAFARLEKQTRDFATLNIKADPSAVKLTDDEVKAYYDEHAKEFMTPDQVVIDYLELKKSSFF
DQVAVKDEDLQAAYQKEIANLSEQRRAAHILIEVNDKTTEAQAKAKIEEVQARLAKGEKFEALAKEFSQDPGSANNGGDL
GYAGPGVYDPAFEKALYSLNKDQVSEPVRTDFGFHLIKLLGVEAPEVPTLASLKDKLTRELKTQQVEQRFVEATKQLEDS
SFEASDLAQPAQDLKLTVHTSKPFGREGGEGVAANRAVVTAAFSTEVLEEGANSTAIELDPETVIVLRAKEHLKPAQLPL
ESVAAAIRTQLTKEHASAAAKTHAEQLIASLRDGKTPLDKAVDGQSWKVTEAANRAQEGVDPAVLQALFRMPKPAAKDKP
TFTSVTLADGSLTIVRLNGVNEAAAPTDEEKAQYRRFLASRVGQQDFAAYRKQLEAEADIKRF

Sequences:

>Translated_623_residues
MLQNIRDNSQGWIAKTIIGVIVALMALTGFDAIFQATTHKNEAAKVNGEEISQNELSQAVDMQRRQLMQQLGKDFDASLL
DEKMLRESALKGLIDRKLLLQGAEQSKFAFSEAALDQVILQTPEFQVDGKFSSDRFDQVIRQLGYSRMQFRQMLAQEMLI
GQLRAGVAGSGFVTDAQVLAFARLEKQTRDFATLNIKADPSAVKLTDDEVKAYYDEHAKEFMTPDQVVIDYLELKKSSFF
DQVAVKDEDLQAAYQKEIANLSEQRRAAHILIEVNDKTTEAQAKAKIEEVQARLAKGEKFEALAKEFSQDPGSANNGGDL
GYAGPGVYDPAFEKALYSLNKDQVSEPVRTDFGFHLIKLLGVEAPEVPTLASLKDKLTRELKTQQVEQRFVEATKQLEDS
SFEASDLAQPAQDLKLTVHTSKPFGREGGEGVAANRAVVTAAFSTEVLEEGANSTAIELDPETVIVLRAKEHLKPAQLPL
ESVAAAIRTQLTKEHASAAAKTHAEQLIASLRDGKTPLDKAVDGQSWKVTEAANRAQEGVDPAVLQALFRMPKPAAKDKP
TFTSVTLADGSLTIVRLNGVNEAAAPTDEEKAQYRRFLASRVGQQDFAAYRKQLEAEADIKRF
>Mature_623_residues
MLQNIRDNSQGWIAKTIIGVIVALMALTGFDAIFQATTHKNEAAKVNGEEISQNELSQAVDMQRRQLMQQLGKDFDASLL
DEKMLRESALKGLIDRKLLLQGAEQSKFAFSEAALDQVILQTPEFQVDGKFSSDRFDQVIRQLGYSRMQFRQMLAQEMLI
GQLRAGVAGSGFVTDAQVLAFARLEKQTRDFATLNIKADPSAVKLTDDEVKAYYDEHAKEFMTPDQVVIDYLELKKSSFF
DQVAVKDEDLQAAYQKEIANLSEQRRAAHILIEVNDKTTEAQAKAKIEEVQARLAKGEKFEALAKEFSQDPGSANNGGDL
GYAGPGVYDPAFEKALYSLNKDQVSEPVRTDFGFHLIKLLGVEAPEVPTLASLKDKLTRELKTQQVEQRFVEATKQLEDS
SFEASDLAQPAQDLKLTVHTSKPFGREGGEGVAANRAVVTAAFSTEVLEEGANSTAIELDPETVIVLRAKEHLKPAQLPL
ESVAAAIRTQLTKEHASAAAKTHAEQLIASLRDGKTPLDKAVDGQSWKVTEAANRAQEGVDPAVLQALFRMPKPAAKDKP
TFTSVTLADGSLTIVRLNGVNEAAAPTDEEKAQYRRFLASRVGQQDFAAYRKQLEAEADIKRF

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=631, Percent_Identity=29.7939778129952, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1786238, Length=116, Percent_Identity=50, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68635; Mature: 68635

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQNIRDNSQGWIAKTIIGVIVALMALTGFDAIFQATTHKNEAAKVNGEEISQNELSQAV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHH
DMQRRQLMQQLGKDFDASLLDEKMLRESALKGLIDRKLLLQGAEQSKFAFSEAALDQVIL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QTPEFQVDGKFSSDRFDQVIRQLGYSRMQFRQMLAQEMLIGQLRAGVAGSGFVTDAQVLA
CCCCEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FARLEKQTRDFATLNIKADPSAVKLTDDEVKAYYDEHAKEFMTPDQVVIDYLELKKSSFF
HHHHHHHCCCEEEEEEECCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DQVAVKDEDLQAAYQKEIANLSEQRRAAHILIEVNDKTTEAQAKAKIEEVQARLAKGEKF
HHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHH
EALAKEFSQDPGSANNGGDLGYAGPGVYDPAFEKALYSLNKDQVSEPVRTDFGFHLIKLL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHH
GVEAPEVPTLASLKDKLTRELKTQQVEQRFVEATKQLEDSSFEASDLAQPAQDLKLTVHT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHCEEEEEC
SKPFGREGGEGVAANRAVVTAAFSTEVLEEGANSTAIELDPETVIVLRAKEHLKPAQLPL
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEECCCEEEEEECHHHCCHHCCCH
ESVAAAIRTQLTKEHASAAAKTHAEQLIASLRDGKTPLDKAVDGQSWKVTEAANRAQEGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEHHHHHHHHHCC
DPAVLQALFRMPKPAAKDKPTFTSVTLADGSLTIVRLNGVNEAAAPTDEEKAQYRRFLAS
CHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RVGQQDFAAYRKQLEAEADIKRF
HCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLQNIRDNSQGWIAKTIIGVIVALMALTGFDAIFQATTHKNEAAKVNGEEISQNELSQAV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHH
DMQRRQLMQQLGKDFDASLLDEKMLRESALKGLIDRKLLLQGAEQSKFAFSEAALDQVIL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QTPEFQVDGKFSSDRFDQVIRQLGYSRMQFRQMLAQEMLIGQLRAGVAGSGFVTDAQVLA
CCCCEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
FARLEKQTRDFATLNIKADPSAVKLTDDEVKAYYDEHAKEFMTPDQVVIDYLELKKSSFF
HHHHHHHCCCEEEEEEECCCCEEEECHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DQVAVKDEDLQAAYQKEIANLSEQRRAAHILIEVNDKTTEAQAKAKIEEVQARLAKGEKF
HHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHH
EALAKEFSQDPGSANNGGDLGYAGPGVYDPAFEKALYSLNKDQVSEPVRTDFGFHLIKLL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHH
GVEAPEVPTLASLKDKLTRELKTQQVEQRFVEATKQLEDSSFEASDLAQPAQDLKLTVHT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHCEEEEEC
SKPFGREGGEGVAANRAVVTAAFSTEVLEEGANSTAIELDPETVIVLRAKEHLKPAQLPL
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEECCCEEEEEECHHHCCHHCCCH
ESVAAAIRTQLTKEHASAAAKTHAEQLIASLRDGKTPLDKAVDGQSWKVTEAANRAQEGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEEHHHHHHHHHCC
DPAVLQALFRMPKPAAKDKPTFTSVTLADGSLTIVRLNGVNEAAAPTDEEKAQYRRFLAS
CHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RVGQQDFAAYRKQLEAEADIKRF
HCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]