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The map label for this gene is yafC [H]

Identifier: 77459913

GI number: 77459913

Start: 4177000

End: 4177899

Strand: Reverse

Name: yafC [H]

Synonym: Pfl01_3691

Alternate gene names: 77459913

Gene position: 4177899-4177000 (Counterclockwise)

Preceding gene: 77459915

Following gene: 77459912

Centisome position: 64.89

GC content: 61.89

Gene sequence:

>900_bases
ATGGACAGCCTGGGCAGTATTTCGGTGTTCGTGCAGGTGGCGGAAACCCGCAGTTTTACTGAGACCGGCCGCTTGCAGGG
CGTGTCCTCGTCGGCGGTTGGCAAAAGCATCGCCCGCCTGGAAGCACGACTCAATGTGCGCTTGTTTCACCGCACCACCC
GCAGCATCACGCTGACCAGCGAAGGCACGCTGTTTCTGGAGCGTTGCCGCAAGATTCTTGCTGAGGTCGAAGCAGCCGAA
TTCGAGTTGTGCGATGCGGCAGCGGCGCCTCACGGCAATTTGCGGGTCAGCCTGCCGCAGGTACATGACCTGGTGATGCC
GGTCATGAACGAGTTCATGGCGTTGTACCCGCAGATCGAACTGGATCTGGACCTGACCGACCGCATGGTCGATGTGGTTG
AAGAAGGTTTCGATGCGGTGATTCGGACGGGTAAACCGCGAGATTCGCGACTGATGGCACGACCGTTGGGCGAGTTTCAT
ATGGTGTTGGTGGCCAGCCCCGCGTACCTGCGCGAGCGCGGCGAACCGCTGACCCCGGCCGATCTGGCGGAGCACGCCTG
CCTGCGCCATACGTTTCACGCCACCGGCAAACTGGAGTCCTGGCCGTTCAATCGCGAAGAGGGCGCTCCCGAGCCGACCT
TGCCGACACGCCTGGTCAGTACGTCGATCGAAGCCGTGCGGCATGCAGCGCTGGCGGGCATGGGCATCGCTTGTCTGCCG
GACTTCATGATCTTCGAGGCGCAGCAGCAGGGTCGCCTGCAGCGCGTGCTCGATGAGCATCTGGAGCACGTCGGGCAGTT
CTGGGTCCTGTGGCCATCAAGCCGGCATGCAACCGCCAAATTGCGCGTGTTCATCGATCATTTATCGGCGCGACTTTTTC
CTGTCGCCCATGACCGGTAG

Upstream 100 bases:

>100_bases
AGGAGACGAAGGCCATAGGGTAGGGCGCTGCACATTCGGGAAAAACAGGTTAGGGTTCCGAACATCTCGGACAAGAATGT
CGTGAATCAGGGAGGGATGA

Downstream 100 bases:

>100_bases
AGTTGTAACTGTTTTAAGACACTAATCCATACGCCGCGGGGCAGCGATCTGTTGCACAATACGCCCCGGACCGTTTTCCC
CTCAGGATGTTTAATGTTGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDSLGSISVFVQVAETRSFTETGRLQGVSSSAVGKSIARLEARLNVRLFHRTTRSITLTSEGTLFLERCRKILAEVEAAE
FELCDAAAAPHGNLRVSLPQVHDLVMPVMNEFMALYPQIELDLDLTDRMVDVVEEGFDAVIRTGKPRDSRLMARPLGEFH
MVLVASPAYLRERGEPLTPADLAEHACLRHTFHATGKLESWPFNREEGAPEPTLPTRLVSTSIEAVRHAALAGMGIACLP
DFMIFEAQQQGRLQRVLDEHLEHVGQFWVLWPSSRHATAKLRVFIDHLSARLFPVAHDR

Sequences:

>Translated_299_residues
MDSLGSISVFVQVAETRSFTETGRLQGVSSSAVGKSIARLEARLNVRLFHRTTRSITLTSEGTLFLERCRKILAEVEAAE
FELCDAAAAPHGNLRVSLPQVHDLVMPVMNEFMALYPQIELDLDLTDRMVDVVEEGFDAVIRTGKPRDSRLMARPLGEFH
MVLVASPAYLRERGEPLTPADLAEHACLRHTFHATGKLESWPFNREEGAPEPTLPTRLVSTSIEAVRHAALAGMGIACLP
DFMIFEAQQQGRLQRVLDEHLEHVGQFWVLWPSSRHATAKLRVFIDHLSARLFPVAHDR
>Mature_299_residues
MDSLGSISVFVQVAETRSFTETGRLQGVSSSAVGKSIARLEARLNVRLFHRTTRSITLTSEGTLFLERCRKILAEVEAAE
FELCDAAAAPHGNLRVSLPQVHDLVMPVMNEFMALYPQIELDLDLTDRMVDVVEEGFDAVIRTGKPRDSRLMARPLGEFH
MVLVASPAYLRERGEPLTPADLAEHACLRHTFHATGKLESWPFNREEGAPEPTLPTRLVSTSIEAVRHAALAGMGIACLP
DFMIFEAQQQGRLQRVLDEHLEHVGQFWVLWPSSRHATAKLRVFIDHLSARLFPVAHDR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=286, Percent_Identity=35.6643356643357, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=32.5342465753425, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=31.0344827586207, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=29.0102389078498, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=34.2560553633218, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789639, Length=308, Percent_Identity=29.2207792207792, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789440, Length=290, Percent_Identity=25.5172413793103, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1789173, Length=284, Percent_Identity=27.4647887323944, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=24.8275862068966, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786448, Length=284, Percent_Identity=25.3521126760563, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI145693105, Length=251, Percent_Identity=27.4900398406374, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI157672245, Length=120, Percent_Identity=34.1666666666667, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=226, Percent_Identity=23.4513274336283, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33422; Mature: 33422

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLGSISVFVQVAETRSFTETGRLQGVSSSAVGKSIARLEARLNVRLFHRTTRSITLTS
CCCCCCEEEEEEEHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHCEEEEEECCCEEEEEC
EGTLFLERCRKILAEVEAAEFELCDAAAAPHGNLRVSLPQVHDLVMPVMNEFMALYPQIE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCEE
LDLDLTDRMVDVVEEGFDAVIRTGKPRDSRLMARPLGEFHMVLVASPAYLRERGEPLTPA
EECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEEEEECCHHHHHCCCCCCHH
DLAEHACLRHTFHATGKLESWPFNREEGAPEPTLPTRLVSTSIEAVRHAALAGMGIACLP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCC
DFMIFEAQQQGRLQRVLDEHLEHVGQFWVLWPSSRHATAKLRVFIDHLSARLFPVAHDR
HHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDSLGSISVFVQVAETRSFTETGRLQGVSSSAVGKSIARLEARLNVRLFHRTTRSITLTS
CCCCCCEEEEEEEHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHCEEEEEECCCEEEEEC
EGTLFLERCRKILAEVEAAEFELCDAAAAPHGNLRVSLPQVHDLVMPVMNEFMALYPQIE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCEE
LDLDLTDRMVDVVEEGFDAVIRTGKPRDSRLMARPLGEFHMVLVASPAYLRERGEPLTPA
EECCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEEEEECCHHHHHCCCCCCHH
DLAEHACLRHTFHATGKLESWPFNREEGAPEPTLPTRLVSTSIEAVRHAALAGMGIACLP
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCC
DFMIFEAQQQGRLQRVLDEHLEHVGQFWVLWPSSRHATAKLRVFIDHLSARLFPVAHDR
HHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]